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21. 发明授权

US08709418B2 Pharmaceutical composition for treating CAPRIN-1 expressing cancer 有权
标题翻译：用于治疗表达CAPRIN-1的癌症的药物组合物
公开(公告)号：US08709418B2
公开(公告)日：2014-04-29
申请号：US13576955
申请日：2011-02-04
申请人： Fumiyoshi Okano , Takanori Saito
发明人： Fumiyoshi Okano , Takanori Saito
IPC分类号： A61K39/395 , C07K16/30 , A61K35/02
CPC分类号： C07K16/30 , A61K2039/505 , C07K16/3015 , C07K16/3053 , C07K2317/23 , C07K2317/24 , C07K2317/34 , C07K2317/732 , C07K2317/734
摘要： According to the present invention, a cancer antigen protein to be specifically expressed on the surfaces of cancer cells is identified and thus the use of an antibody targeting the cancer antigen protein as an agent for treating and/or preventing a cancer is provided. Specifically, the present invention provides a pharmaceutical composition for treating and/or preventing a cancer, which comprises an antibody comprising a heavy chain variable region that comprises SEQ ID NOS: 39, 40, and 41 and a light chain variable region that comprises SEQ ID NOS: 43, 44, and 45 or a fragment thereof as an active ingredient and having immunological reactivity with a CAPRIN-1 protein.
摘要翻译：根据本发明，鉴定在癌细胞表面特异性表达的癌抗原蛋白，因此提供了靶向癌抗原蛋白的抗体作为治疗和/或预防癌症的药剂的用途。具体而言，本发明提供了用于治疗和/或预防癌症的药物组合物，其包含含有包含SEQ ID NO：39,40和41的重链可变区的抗体和包含SEQ ID NO：39,40和41的轻链可变区， NOS：43,44和45或其片段作为活性成分，并与CAPRIN-1蛋白具有免疫反应性。

22. 发明申请

US20120064469A1 VERTICAL-TYPE HEAT TREATMENT APPARATUS, AND CONTROL METHOD FOR SAME 审中-公开
标题翻译：垂直式热处理装置及其控制方法
公开(公告)号：US20120064469A1
公开(公告)日：2012-03-15
申请号：US13221209
申请日：2011-08-30
申请人： Koji YOSHII , Tatsuya Yamaguchi , Wenling Wang , Takanori Saito
发明人： Koji YOSHII , Tatsuya Yamaguchi , Wenling Wang , Takanori Saito
IPC分类号： F27D19/00 , F27D7/00 , F27D11/02 , F27B1/24
CPC分类号： F27B17/0025 , H01L21/67109 , H01L21/67248
摘要： A heat treatment apparatus and control method enabling the apparatus to settle down the internal temperature of a treating vessel to a target temperature accurately and quickly. The apparatus includes a furnace body with a heater on an inner circumferential surface thereof, a treating vessel disposed inside the furnace body, a cooling medium supply blower and cooling medium release blower connected to the furnace body, and a temperature sensor provided inside the treating vessel. A signal from the temperature sensor is sent to a heater output computing unit of a controller. The computing unit determines a heater output level to be obtained during temperature regulation with the heater only, the heater output level being based on a preset temperature that has been determined by a temperature determining unit and temperature detected by the temperature sensor. A blower output computing unit activates blower output based on the heater output level.
摘要翻译：一种热处理装置和控制方法，使得该装置能够准确而快速地将处理容器的内部温度降至目标温度。该装置包括在炉体内部具有加热器的炉体，设置在炉体内的处理容器，与炉体连接的冷却介质供给鼓风机和冷却介质排出鼓风机，以及设置在处理容器内的温度传感器。来自温度传感器的信号被发送到控制器的加热器输出计算单元。计算单元确定仅在加热器的温度调节期间获得的加热器输出水平，加热器输出水平基于由温度确定单元确定的预设温度和由温度传感器检测的温度。鼓风机输出计算单元基于加热器输出电平激活鼓风机输出。

23. 发明授权

US08128567B2 Ultrasonic imaging apparatus 有权
标题翻译：超声波成像装置
公开(公告)号：US08128567B2
公开(公告)日：2012-03-06
申请号：US12342185
申请日：2008-12-23
申请人： Sei Kato , Takanori Saito
发明人： Sei Kato , Takanori Saito
IPC分类号： A61B8/14 , A61B8/00
CPC分类号： A61B8/467 , A61B8/461 , A61B8/469 , A61B8/481 , A61B8/56
摘要： An ultrasonic imaging apparatus includes an image obtaining unit for irradiating an imaging region and obtaining tomographic image information that draws the imaging region, an input unit for inputting scan parameter value information and a target sound pressure parameter value as an index of an estimated sound pressure in the subject, an estimated maximum sound pressure parameter value calculating device for calculating an estimated maximum sound pressure parameter value in the subject on the basis of the scan parameter value information and maximum drive voltage information of a piezoelectric transducer group for generating an ultrasonic wave, and a maximum drive voltage optimization device for comparing the estimated maximum sound pressure parameter value and the target sound pressure parameter value and optimizing the maximum drive voltage value of the maximum drive voltage information.
摘要翻译：超声波成像装置包括图像获取单元，用于照射成像区域并获得绘制成像区域的断层图像信息;输入单元，用于输入扫描参数值信息和目标声压参数值作为估计声压的指标所述被摄体，估计的最大声压参数值计算装置，用于根据用于产生超声波的压电换能器组的扫描参数值信息和最大驱动电压信息来计算被摄体中的估计最大声压参数值;以及最大驱动电压优化装置，用于比较估计的最大声压参数值和目标声压参数值，并优化最大驱动电压信息的最大驱动电压值。

24. 发明申请

US20110123492A1 IMMUNITY-INDUCING AGENT 有权
标题翻译：免疫诱导剂
公开(公告)号：US20110123492A1
公开(公告)日：2011-05-26
申请号：US13056122
申请日：2009-08-05
申请人： Fumiyoshi Okano , Masaki Shimizu , Takanori Saito
发明人： Fumiyoshi Okano , Masaki Shimizu , Takanori Saito
IPC分类号： A61K38/20 , C12N15/63 , C07K14/47 , A61K39/00 , A61K38/21 , C12N5/078 , C12N5/0783 , A61P35/00 , A61P37/04 , C07K7/06 , A61P35/02
CPC分类号： A61K39/0011 , A61K38/00 , A61K38/19 , A61K2039/53 , C07K14/47 , C07K14/4748 , C12N5/0634 , C12N5/0636 , A61K2300/00
摘要： The invention relates to an immunity-inducing agent comprising, as an active ingredient, at least one polypeptide having immunity-inducing activity that is selected from among polypeptides (a), (b), and (c): (a) a polypeptide of at least seven contiguous amino acids of the amino acid sequence shown by any even SEQ ID number selected from SEQ ID NOs: 2 to 30 listed in the Sequence Listing; (b) a polypeptide of at least seven amino acids having 90% or more sequence identity with the polypeptide (a); and (c) a polypeptide comprising the polypeptide (a) or (b) as a partial sequence thereof, or a recombinant vector comprising a polynucleotide encoding said polypeptide and capable of expressing said polypeptide in vivo.
摘要翻译：本发明涉及一种免疫诱导剂，其包含作为活性成分的至少一种具有免疫诱导活性的多肽，其选自多肽（a），（b）和（c）：（a）多肽氨基酸序列的至少七个连续氨基酸由选自序列表中所列的SEQ ID NO：2至30的任何偶数SEQ ID号表示; （b）与多肽（a）具有90％或更多序列同一性的至少7个氨基酸的多肽; 以及（c）包含多肽（a）或（b）作为其部分序列的多肽，或包含编码所述多肽并能够在体内表达所述多肽的多核苷酸的重组载体。

25. 发明申请

US20050028738A1 Thermal treating apparatus 有权
标题翻译：热处理设备
公开(公告)号：US20050028738A1
公开(公告)日：2005-02-10
申请号：US10494970
申请日：2002-09-27
申请人： Takanori Saito , Toshiyuki Makiya , Hisaei Osanai , Tsuyoshi Takizawa , Tomohisa Shimazu , Kazuhide Hasebe , Hiroyuki Yamamoto , Yukimasa Saito , Kenichi Yamaga
发明人： Takanori Saito , Toshiyuki Makiya , Hisaei Osanai , Tsuyoshi Takizawa , Tomohisa Shimazu , Kazuhide Hasebe , Hiroyuki Yamamoto , Yukimasa Saito , Kenichi Yamaga
IPC分类号： C23C16/44 , C23C16/455 , H01L21/00 , H01L21/205 , H01L21/22 , C23C16/00
CPC分类号： H01L21/67109 , H01L21/67098
摘要： The present invention is a thermal processing unit including: a heating-furnace body whose upper end has an opening; a heating unit provided on an inside wall of the heating-furnace body; a reaction container consisting of a single tube contained in the heating-furnace body; a gas-discharging-pipe connecting portion formed at an upper portion of the reaction container; and a first temperature controlling unit provided around the gas-discharging-pipe connecting portion.
摘要翻译：本发明是一种热处理单元，包括：上端具有开口的加热炉体; 设置在所述加热炉体的内壁上的加热单元; 由包含在加热炉体内的单个管构成的反应容器; 形成在反应容器的上部的气体排出管连接部; 以及设置在气体排出管连接部周围的第一温度控制单元。

26. 发明授权

US06235821B1 Cleansing thermoplastic resin composition 有权
标题翻译：清洁热塑性树脂组合物
公开(公告)号：US06235821B1
公开(公告)日：2001-05-22
申请号：US09402250
申请日：1999-12-08
申请人： Takanori Saito
发明人： Takanori Saito
IPC分类号： C08K542
CPC分类号： C08L55/02 , B29C33/722 , B29C47/0011 , B29C47/0877 , C08K5/42 , C08L23/06 , C08L23/10 , C08L25/06 , C08L25/14 , C08L101/00 , C08L2205/02 , C09D133/12 , C08L33/12 , C08L2666/04 , C08L2666/02
摘要： The invention provides thermoplastic resin compositions for purging which comprise a thermoplastic resin and a methyl methacrylate/styrene copolymer incorporated therein. According to the invention, thermoplastic resin compositions for purging molding machines, which have an excellent cleaning ability, can be obtained.
摘要翻译：本发明提供了包含热塑性树脂和其中加入的甲基丙烯酸甲酯/苯乙烯共聚物的用于清洗的热塑性树脂组合物。根据本发明，可以获得具有优异的清洗能力的用于吹扫成型机的热塑性树脂组合物。

27. 发明授权

US6043468A Carbon heater 失效
标题翻译：碳加热器
公开(公告)号：US6043468A
公开(公告)日：2000-03-28
申请号：US126847
申请日：1998-07-31
申请人： Eiichi Toya , Masahiko Ichishima , Tomio Konn , Tomohiro Nagata , Shigeru Yamamura , Norihiko Saito , Kouji Teraoka , Takeshi Inaba , Hiroyuki Honma , Ken Nakao , Takanori Saito , Hisaei Osanai , Toshiyuki Makiya
发明人： Eiichi Toya , Masahiko Ichishima , Tomio Konn , Tomohiro Nagata , Shigeru Yamamura , Norihiko Saito , Kouji Teraoka , Takeshi Inaba , Hiroyuki Honma , Ken Nakao , Takanori Saito , Hisaei Osanai , Toshiyuki Makiya
IPC分类号： C30B15/14 , C30B35/00 , H05B3/44
CPC分类号： C30B35/00 , C30B15/14 , H05B2203/003
摘要： A carbon heater comprising heater members (11, 111, 121 . . . 161, 212, 222, 315, 325 . . . 345, 411, 515, 612) in which a plurality of carbon fiber bundles having a plurality of carbon fibers whose diameter is 5 to 15 .mu.m bundled are woven into a longitudinally elongated shape such as a wire shape or a tape shape and the impurity content is less than 10 ppm in ashes.
摘要翻译：一种碳加热器，包括加热器构件（11,111,121,161,212,222,315,325,354,411,515,612），其中多个碳纤维束具有多个碳纤维，捆扎的直径为5〜15μm被编织成纵向细长形状，例如线状或带状，杂质含量在灰分中小于10ppm。

28. 发明授权

US5426337A Sheet metal casing for a small electric motor 失效
标题翻译：用于小型电动机的钣金套管
公开(公告)号：US5426337A
公开(公告)日：1995-06-20
申请号：US753241
申请日：1991-08-30
申请人： Kyoji Kobayashi , Atsushi Inagaki , Takanori Saito , Yoshimi Takano , Junichi Sato
发明人： Kyoji Kobayashi , Atsushi Inagaki , Takanori Saito , Yoshimi Takano , Junichi Sato
IPC分类号： B21C37/10 , H02K5/04 , H02K5/15 , H02K7/08 , H02K7/116 , H02K5/00
CPC分类号： B21C37/104 , B21C37/108 , H02K5/04 , H02K5/15 , H02K7/081 , H02K7/1166 , H02K2205/03 , Y10T29/49009
摘要： A small-sized electric motor includes a yoke formed by bending a rectangular metallic plate into an oval shaped tube having a pair of flat parts and a pair of arcuate parts and joining opposite ends of the metallic plate. An end cap is secured on one end of the yoke and a gear casing is secured to the yoke by a tab formed on another end of the yoke. The joining faces of the metallic plate are located away from the center line of an arcuate part of the yoke and jagged faces are formed on the joining faces. The jagged faces are composed only of curved parts and straight parts having inclinations to the axis of the yoke. The end cap is secured by crimping a bendable tab formed on one end of the yoke by burring. A tab for securing the yoke to a gear box is formed by bending a tongue provided on the metallic plate together with notches on both sides of the tongue.
摘要翻译：小型电动机包括通过将矩形金属板弯曲成具有一对扁平部分和一对弓形部分并且与金属板的相对端相连接的椭圆形管而形成的轭。端盖固定在轭的一端，并且齿轮壳通过形成在轭的另一端上的突片固定到轭。金属板的接合面远离轭的弓形部分的中心线，并且在接合面上形成锯齿状的面。锯齿状的表面仅由弯曲部分和具有向轭的轴线倾斜的直线部分组成。端盖通过卷边形成在轭的一端上的可弯曲接头来固定。通过将设置在金属板上的舌片与舌头两侧的凹口一起弯曲来形成用于将轭固定到齿轮箱的突片。

29. 发明授权

US5413794A Percutaneous absorption promoter, a tape plaster and a method of promoting percutaneous absorpton 失效
标题翻译：经皮吸收促进剂，胶带膏和促进经皮吸收剂的方法
公开(公告)号：US5413794A
公开(公告)日：1995-05-09
申请号：US937783
申请日：1992-09-01
申请人： Eiji Suzuki , Hideaki Okabe , Takanori Saito
发明人： Eiji Suzuki , Hideaki Okabe , Takanori Saito
IPC分类号： A61K9/70 , A61K47/18 , C07C229/56 , C07C233/54 , A61F13/00
CPC分类号： A61K9/7061 , A61K47/18 , A61K47/183 , A61K9/0014 , Y10S514/946 , Y10S514/947
摘要： A percutaneous absorption promoter comprises a derivative of amino acid in which the amino group has or does not have an acyl substituent or a hydrocarbon substituent, the carboxylic group has a hydrocarbon substituent and the part between the amino group and the carboxylic group has a specified structure. A tape plaster comprises the percutaneous absorption promoter described above. The method utilizes the the percutaneous absorption promoter described above. The percutaneous promoter of the invention has excellent ability of promoting the percutaneous absorption of pharmacologically active substances and excellent safety simultaneously, capable of delivering the desired pharmacologically active substances rapidly to the location of treatment or to all parts of the body through the circulating system and effective for curing various kinds of disease. The tape plaster comprising it and the method of promoting percutaneous absorption by utilizing it have the same advantages.
摘要翻译：经皮吸收促进剂包括其中氨基具有或不具有酰基取代基或烃取代基的氨基酸衍生物，羧基具有烃取代基，氨基和羧基之间的部分具有特定的结构。胶带包含上述经皮吸收促进剂。该方法利用上述经皮吸收促进剂。本发明的经皮促进剂具有优异的促进药理活性物质的经皮吸收和同时具有优异安全性的能力，能够通过循环系统快速将期望的药理活性物质快速递送至身体的所有部位，用于治疗各种疾病。包含它的胶带膏和利用它促进经皮吸收的方法具有相同的优点。

30. 发明授权

US4738523A Retrieval control apparatus for microfilm reader 失效
标题翻译：微缩胶片读取器检索控制装置
公开(公告)号：US4738523A
公开(公告)日：1988-04-19
申请号：US89056
申请日：1987-08-25
申请人： Masaaki Ito , Yutaka Tanaka , Nobuo Ueda , Takanori Saito , Osami Kato
发明人： Masaaki Ito , Yutaka Tanaka , Nobuo Ueda , Takanori Saito , Osami Kato
IPC分类号： G03B21/11 , G06F17/30 , G03B23/12 , G03B27/52 , G03B27/70
CPC分类号： G03B21/113 , G03B21/118
摘要： The present invention relates to a reader printer having a plurality of mode selection keys, ten-keys and a character display which displays a message indicating contents of input manipulations to be executed next with the ten keys in accordance with the mode selected by the mode selection keys whereby operating conditions of the reader printer under the selected mode are set by way of operator-to-machine conversation.
摘要翻译：本发明涉及一种具有多个模式选择键，十键和字符显示的读取器打印机，该显示器根据由模式选择所选择的模式显示指示使用十个键执行的接下来执行的输入操作的内容的消息键，从而通过操作者到机器的对话来设置读取器打印机在所选模式下的操作条件。

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