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21. 发明申请

US20190117887A1 NEEDLE ASSEMBLY AND DRUG DELIVERY DEVICE HAVING SUCH NEEDLE ASSEMBLY 审中-公开
公开(公告)号：US20190117887A1
公开(公告)日：2019-04-25
申请号：US16093184
申请日：2017-04-13
申请人： Sanofi-Aventis Deutschland GMBH
发明人： Michael Jugl , Axel Teucher , Stefan Blancke
IPC分类号： A61M5/168 , A61J1/20 , A61M5/162
摘要： Described herein are specialized needle assemblies for injection systems. One example injection system includes a needle assembly configured to removably attach to a drug delivery device and a housing configured to receive a drug cartridge. The needle assembly includes a needle configured to extend through an outlet port of the drug delivery device and establish fluid communication with the drug cartridge within the housing of the drug delivery device. The needle assembly may include a fluid flow sensor monitoring the fluid flow and/or occlusions within the needle assembly, and provide indications of an occluded or clogged needle and/or one or more indications of proper flow through the needle, e.g., non-occlusion of the needle. In some examples, the arrangement of the needle assembly includes sensors to detect an occlusion within a portion of a needle.

22. 发明申请

US20180353702A1 SYSTEM FOR CAP REMOVAL 审中-公开
公开(公告)号：US20180353702A1
公开(公告)日：2018-12-13
申请号：US15778513
申请日：2016-11-21
申请人： Sanofi-Aventis Deutschland GMBH
发明人： Michael Jugl , Stefan Blancke , Axel Teucher , Claudia Biedermann
IPC分类号： A61M5/32
摘要： The present invention relates to a pen injecting device for delivering a liquid medicament comprising a pen body, a needle received in a first end of the pen body, an inner needle shield removeably located over the needle to enclose the needle, an outer needle shield removeably located over the inner needle shield to enclose the inner needle shield and a pen cap removeably attached to the first end of the pen body so as to enclose the outer needle shield. The pen cap comprises an arm depending from an inside surface of the cap and extending away from the first end of the pen body toward the inner and outer needle shields, the arm having a sharp end so that, as the cap is removed from the body, the sharp end of the arm grips the inner or outer needle shield to retain it in the cap and expose the needle.

23. 发明授权

US10117998B2 Assembly for a drug delivery device 有权
公开(公告)号：US10117998B2
公开(公告)日：2018-11-06
申请号：US14770835
申请日：2014-03-10
申请人： Sanofi-Aventis Deutschland GmbH
发明人： Michael Jugl , Axel Teucher
IPC分类号： A61M5/00 , A61M5/315
摘要： An assembly for a drug delivery device is provided, the assembly comprising an actuator which is configured to perform a setting movement in a proximal direction in order to set a dose of a drug, and which is configured to perform a dispense movement in a distal direction in order to dispense a dose of a drug. The assembly further comprises stop mechanism acting after a maximum amount of a drug has been delivered, which is configured to axially constrain the setting movement of the actuator such that the setting of a dose is inhibited, wherein a limited axial movement of the actuator is allowed.

24. 发明申请

US20180036492A1 Medicament delivery device and method for assembling same 审中-公开
公开(公告)号：US20180036492A1
公开(公告)日：2018-02-08
申请号：US15552194
申请日：2016-02-25
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Marc Schader , Axel Teucher
IPC分类号： A61M5/32 , A61M5/20
摘要： The disclosure relates to a medicament delivery device, comprising: a tubular body having a distal end, a cap adapted to be connected to the distal end (of the body, wherein the body comprises a first clip having a first stop and a first ramp, wherein the cap comprises a second clip having a second stop and a second ramp, wherein the first ramp and the second ramp are adapted to be mutually engaged when the cap is connected to the body in a first position, wherein the first ramp and the second ramp are adapted to resiliently deflect at least one of the first clip and the second clip when the cap is being moved from the first position towards a second position, wherein in the second position the first stop and the second stop abut each other to prevent the cap from being moved into the first position. Furthermore, the disclosure relates to a method for assembling the medicament delivery device.

25. 发明授权

US09849246B2 Housing of a drug delivery device 有权
公开(公告)号：US09849246B2
公开(公告)日：2017-12-26
申请号：US14388550
申请日：2013-03-20
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Michael Jugl , Axel Teucher
IPC分类号： A61M5/24 , A61M5/315
CPC分类号： A61M5/24 , A61M5/31525 , A61M2005/2407
摘要： A housing for a drug delivery device is disclosed having a first housing component adapted to receive a cartridge at least partially filled with a medicament, and a second housing component adapted to receive a drive mechanism to operably engage with the cartridge for dispensing of a dose of the medicament, wherein the first housing component comprises an insert portion to be inserted in an axial direction into a corresponding receptacle of the second housing component, and wherein the insert portion comprises at least one radially outwardly extending first interlock member to positively engage and to rotationally lock with a correspondingly shaped second interlock member of the receptacle of the second housing component.

26. 发明授权

US09789258B2 Dose setting mechanism for a drug delivery device 有权
公开(公告)号：US09789258B2
公开(公告)日：2017-10-17
申请号：US14435797
申请日：2013-11-05
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Marc Holtwick , Michael Jugl , Axel Teucher
IPC分类号： A61M5/315 , A61M5/20
CPC分类号： A61M5/3155 , A61M5/20 , A61M5/31583 , A61M2205/42 , A61M2205/581 , A61M2205/583
摘要： The present invention is directed at a dose setting mechanism for a drug delivery device, comprising an outer sleeve and an inner sleeve located at least partially within the outer sleeve wherein the outer sleeve is connected to the inner sleeve. To reduce noise excitations of the dose setting mechanism, at least one intermediate element is at least partially located in a clearance between the inner sleeve and the outer sleeve in such way that it reduces the relative movement of the inner sleeve and the outer sleeve along a play between the inner sleeve and the outer sleeve. The invention is further directed to a pen-type injector equipped with a respective dose setting mechanism.

27. 发明授权

US09486586B2 Drug delivery device and method for detecting a contact 有权
标题翻译：用于检测接触的药物输送装置和方法
公开(公告)号：US09486586B2
公开(公告)日：2016-11-08
申请号：US14421019
申请日：2013-08-15
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Michael Jugl , Axel Teucher
IPC分类号： A61M5/315 , A61M5/31 , G01B5/14 , G01M13/04
CPC分类号： A61M5/31515 , A61M5/3146 , A61M2205/3306 , A61M2205/3327 , A61M2205/583 , G01B5/146 , G01M13/04
摘要： The present invention is directed to a drug delivery device with a drive mechanism including a piston rod with a bearing for driving a bung in a cartridge in a distal direction. A movable element is disposed displacably in an axial direction within the drive mechanism. The moveable element is movable between a first position in which a distal end of said movable element protrudes from said bearing and a second position in which a distal end of said movable element lies flush with the distal end of said bearing. The invention is further directed to a method for detecting the contact between the bearing and the movable bung.
摘要翻译：本发明涉及具有驱动机构的药物输送装置，该驱动机构包括具有用于沿远端方向驱动药筒中的栓的轴承的活塞杆。可移动元件沿驱动机构内的轴向可置换地设置。可移动元件可在其中所述可移动元件的远端从所述轴承突出的第一位置和所述可移动元件的远端与所述轴承的远端齐平的第二位置之间移动。本发明还涉及一种用于检测轴承和活动塞之间的接触的方法。

28. 发明申请

US20160296701A1 HOUSING OF A DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置的住房
公开(公告)号：US20160296701A1
公开(公告)日：2016-10-13
申请号：US15100369
申请日：2014-12-08
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Stefan Blancke , Axel Teucher , Michael Jugl
IPC分类号： A61M5/24 , A61M5/315 , A61M5/32
CPC分类号： A61M5/24 , A61M5/2459 , A61M5/28 , A61M5/3155 , A61M5/3158 , A61M5/32 , A61M5/3286 , A61M2005/2407 , A61M2005/2433 , A61M2005/2462 , A61M2005/2485 , A61M2005/2488
摘要： The present invention relates to a housing of a drug delivery device comprising a cylindrically shaped body (12) to accommodate a drive mechanism (13) and comprising a cartridge holder (14) to accommodate a cartridge (16) containing a dispensable medicament, the housing further comprising a connector assembly (20) to releasably interconnect body (12) and cartridge holder (14), the connector assembly (20) comprising: a tangentially extending recessed structure (30) with a tangential opening (31) to receive a radially extending pin (26), wherein the recessed structure (30) is fastened to one of body (12) and cartridge holder (14) and wherein the pin (26) is fastened to the other one of body (12) and cartridge holder (14), a release member (40) having a retaining portion (42) to cover the opening (31) in a locking configuration (60), wherein the release member (40) is displaceable in tangential direction (3) against a restoring force away from the recessed structure (30) into a release configuration (62), in which the opening (31) is uncovered to tangentially remove the pin (26) therefrom.
摘要翻译：本发明涉及药物输送装置的壳体，其包括圆柱形主体（12），以容纳驱动机构（13）并且包括用于容纳包含可分配药物的药筒（16）的药筒保持器（14），所述外壳还包括用于可释放地互连主体（12）和盒保持器（14）的连接器组件（20），所述连接器组件（20）包括：切向延伸的凹陷结构（30），其具有切向开口（31）销（26），其中所述凹陷结构（30）紧固到主体（12）和盒保持器（14）中的一个，并且其中所述销（26）紧固到主体（12）和盒保持器（14）中的另一个），具有在锁定构型（60）中覆盖所述开口（31）的保持部分（42）的释放构件（40），其中所述释放构件（40）可沿切向方向（3）移动以抵抗恢复力从凹陷结构（30）到释放组件配置（62），其中开口（31）未被覆盖以切向地从其上切除销（26）。

29. 发明申请

US20150238700A1 Method for Assembling a Drug Delivery Device 审中-公开
标题翻译：药物输送装置的组装方法
公开(公告)号：US20150238700A1
公开(公告)日：2015-08-27
申请号：US14421123
申请日：2013-08-15
申请人： Sanofi-Aventis Deutschland GmbH
发明人： Michael Jugl , Axel Teucher
IPC分类号： A61M5/315
CPC分类号： A61M5/31515 , A61M5/3146 , A61M5/31583 , A61M2205/332 , A61M2205/3327 , A61M2205/581 , A61M2207/00 , Y10T29/49826
摘要： The present invention is directed to a method for assembling a drug delivery device with a drive mechanism and a bung movably provided in a cartridge. The drive mechanism includes a piston rod and a bearing for driving the bung in a distal direction, wherein the bearing and the piston rod are configured to be connected via a snap connection and wherein the contact between the drive mechanism and the bung is indicated by a detectable signal produced by the engaging snap connection. The method includes the steps of placing the bearing on the bung, displacing the piston rod towards the bearing such that the snap connection is established, monitoring for the signal and stopping displacement of the piston rod upon detection of the signal. The invention is further directed to drug delivery device produced according to the respective method.
摘要翻译：本发明涉及一种用于组装具有可移动地设置在药筒中的驱动机构和栓的药物输送装置的方法。驱动机构包括活塞杆和用于沿远端方向驱动栓的轴承，其中轴承和活塞杆构造成通过卡扣连接连接，并且其中驱动机构和塞子之间的接触由由接合卡扣连接产生的可检测信号。该方法包括以下步骤：将轴承放置在塞子上，将活塞杆朝向轴承移动，使得卡扣连接被建立，监测信号并且在检测到信号时停止活塞杆的位移。本发明还涉及根据各自方法生产的药物输送装置。

30. 发明申请

US20150224262A1 Medical Device with Impact Resistant Housing 审中-公开
标题翻译：带抗冲击外壳的医疗器械
公开(公告)号：US20150224262A1
公开(公告)日：2015-08-13
申请号：US14424298
申请日：2013-08-25
申请人： Sanofi-Aventis Deutschland GmbH
发明人： Michae Jugl , Axel Teucher
IPC分类号： A61M5/31 , B29D22/00 , B29C65/70
摘要： The present invention relates to a housing of a medical device and to a respective medical device, wherein the housing comprises a body to receive at least one device component and wherein the body is flexibly deformable in response to mechanical impact above a predefined threshold.
摘要翻译：本发明涉及医疗装置的壳体和相应的医疗装置，其中壳体包括容纳至少一个装置部件的主体，并且其中主体响应于高于预定阈值的机械冲击而可灵活地变形。

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