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    • 30. 发明申请
    • METHODS OF IDENTIFYING BIOMARKERS FOR CANCER
    • 识别癌症生物标志物的方法
    • US20110195421A1
    • 2011-08-11
    • US12906158
    • 2010-10-18
    • Richard H. SelinfreundRakesh VigRichard P. Gill
    • Richard H. SelinfreundRakesh VigRichard P. Gill
    • C12Q1/68G01N33/53
    • G01N33/54393A61B10/0045C12Q1/40G01N33/50
    • Methods of Identifying Biomarkers for Cancer. According to at least one embodiment of a method of identifying diagnostic markers of cancer of the present disclosure, the method comprises the steps of contacting a body fluid of a diseased subject having a cancer with a stabilizing agent capable of completely or substantially preventing the degradation or inactivation of a diagnostic marker, analyzing the stabilized body fluid to determine at last one property of the diagnostic marker to create a cancer profile, comparing the cancer profile with a control profile of a healthy subject not having the cancer, wherein the control profile is created in a like manner to the cancer profile, and generating a cancer identifier panel from the compared cancer profile, wherein the cancer identifier panel contains at least one cancer diagnostic marker indicative of the cancer.
    • 识别癌症生物标志物的方法。 根据鉴定本公开内容的癌症诊断标记物的方法的至少一个实施方案,所述方法包括以下步骤:将具有癌症的患病患者的体液与能够完全或基本上防止降解的稳定剂接触,或 诊断标记物的失活,分析稳定的体液以确定诊断标记物的最后一个性质以产生癌症谱,将癌症谱与不具有癌症的健康受试者的对照谱进行比较,其中产生控制谱 以与癌症概况相似的方式,以及从所述比较的癌症谱中产生癌症识别器组,其中所述癌症识别器组包含至少一个指示癌症的癌症诊断标志物。