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21. 发明申请

US20110270051A1 Cardiovascular Disease Screening Method and Apparatus 审中-公开
标题翻译：心血管疾病筛查方法与装置
公开(公告)号：US20110270051A1
公开(公告)日：2011-11-03
申请号：US13099606
申请日：2011-05-03
申请人： Morteza Naghavi , Albert Andrew Yen , Haider Ali Hassan , David S. Panthagani
发明人： Morteza Naghavi , Albert Andrew Yen , Haider Ali Hassan , David S. Panthagani
IPC分类号： A61B5/00
CPC分类号： A61B5/0205 , A61B5/02007 , A61B5/02028 , A61B5/02108 , A61B5/022 , A61B5/029 , A61B5/0402 , A61B5/0535 , A61B5/145 , A61B5/7275 , A61B8/0883 , A61B8/0891 , A61B8/485 , G16H40/63 , G16H50/20 , G16H50/30
摘要： The disclosure teaches non-invasive, inexpensive and reproducible tests that provide improved measurement of risk assessment by measurement of the following parameters of a subject. The disclosure includes intima-media thickness, augmentation index, arterial wall elasticity, central arterial pressure, electrocardiogram impedance, cardiograph blood pressure measurement, ankle-brachial index, 3D (three dimensional) plaque volume, vessel wall volume, and diameter waveform pattern characterization. Further, the disclosure teaches that satisfactory measurement of risk assessment may be achieved by conducting any four of the aforementioned tests.
摘要翻译：该公开内容教导了非侵入性，廉价和可再现的测试，其通过测量受试者的以下参数来提供对风险评估的改进的测量。该公开内容包括内膜 - 中膜厚度，增大指数，动脉壁弹性，中心动脉压，心电图阻抗，心电图血压测量，踝肱指数，3D（三维）斑块体积，血管壁体积和直径波形图表征。此外，该公开内容教导了可以通过进行上述任何四个测试来实现令人满意的风险评估测量。

22. 发明授权

US06451044B1 Method and apparatus for heating inflammed tissue 失效
公开(公告)号：US06451044B1
公开(公告)日：2002-09-17
申请号：US09473919
申请日：1999-12-28
申请人： Morteza Naghavi , Bujin Guo , Birendra Lal , S. Ward Casscells, III , James T. Willerson
发明人： Morteza Naghavi , Bujin Guo , Birendra Lal , S. Ward Casscells, III , James T. Willerson
IPC分类号： A61N100
CPC分类号： A61F2/86 , A61B2017/22001 , A61F2007/0088 , A61N5/0601 , A61N7/02
摘要： The present invention relates to methods for treating inflammation in body tissues. More specifically, certain disclosed methods relate to selectively inducing apoptosis in inflammatory immune cells by heating cells for a sufficient time and at a sufficient temperature to induce programmed cell death. The disclosed stents can be placed in contact with the inflammatory cells and heated under controlled conditions. The disclosed apparatus and methods are particularly suitable for treating athersclerotic plaques.

23. 发明申请

US20120177631A1 Composition for Health Promoting Compounds 审中-公开
标题翻译：健康促进化合物的组成
公开(公告)号：US20120177631A1
公开(公告)日：2012-07-12
申请号：US13346811
申请日：2012-01-10
申请人： Morteza Naghavi , Albert Andrew Yen , Mortaza Mark Naghavi
发明人： Morteza Naghavi , Albert Andrew Yen , Mortaza Mark Naghavi
IPC分类号： A61K33/30 , A61P3/00 , A61P3/06 , A61K36/899 , A61P9/00
CPC分类号： A61K36/899 , A23L33/10 , A23L33/105 , A23L33/11 , A23L33/12 , A23L33/15 , A23V2002/00 , A61K31/05 , A61K31/352 , A61K31/4415 , A61K31/445 , A61K31/519 , A61K31/592 , A61K31/714 , A61K33/06 , A61K33/30 , A61K2300/00 , A23V2200/326 , A23V2200/3262 , A23V2250/0606 , A23V2250/0644 , A23V2250/161 , A23V2250/1642 , A23V2250/1882 , A23V2250/21168 , A23V2250/213 , A23V2250/2136 , A23V2250/7046 , A23V2250/7052 , A23V2250/706 , A23V2250/7106
摘要： This invention relates to orally ingested compositions for improving cardiovascular health and reducing the overall levels of cholesterol by lowering the levels of low density lipoprotein (LDL) and triglycerides, increasing the level and density of high density lipoprotein (HDL), assisting with blood pressure control, or improve some aspect of cardiovascular function, and thus preferably assisting with cardiovascular health when administered to mammals, including humans.
摘要翻译：本发明涉及通过降低低密度脂蛋白（LDL）和甘油三酸酯的水平，增加高密度脂蛋白（HDL）的水平和密度来改善心血管健康并降低胆固醇水平的口服摄取组合物，辅助血压控制或改善心血管功能的某些方面，因此优选在对包括人在内的哺乳动物施用时辅助心血管健康。

24. 发明授权

US08212554B2 Intraluminal magneto sensor system and method of use 有权
标题翻译：管腔内磁传感器系统及其使用方法
公开(公告)号：US08212554B2
公开(公告)日：2012-07-03
申请号：US11918205
申请日：2006-05-11
申请人： Audrius Brazdeikis , Jaroslaw Wosik , Paul Cherukuri , Morteza Naghavi
发明人： Audrius Brazdeikis , Jaroslaw Wosik , Paul Cherukuri , Morteza Naghavi
IPC分类号： G01R33/02
CPC分类号： G01R33/02 , A61B5/05 , A61B5/06
摘要： A system (100) including a catheter mounted magneto sensor (114), such as a superconducting quantum interference device (SQUID), and methods using the system are disclosed, where the system and method are designed to detect changes in a magnetic field in a body of interest, such as a patient, to detect changes in a magnetic field in a patient, to identify loci in a target body that accumulate magnetic particles or to identify vulnerable plague in a patient.
摘要翻译：公开了一种包括诸如超导量子干涉装置（SQUID）的导管安装的磁传感器（114）的系统（100）以及使用该系统的方法，其中该系统和方法被设计为检测一个磁场中的磁场的变化感兴趣的身体，例如患者，以检测患者的磁场的变化，以识别靶体内存在磁性颗粒的位点或识别患者中易受伤害的瘟疫。

25. 发明授权

US08109982B2 Non-invasive modulation of the autonomic nervous system 失效
标题翻译：无创调制的自主神经系统
公开(公告)号：US08109982B2
公开(公告)日：2012-02-07
申请号：US11425919
申请日：2006-06-22
申请人： Morteza Naghavi
发明人： Morteza Naghavi
IPC分类号： A61F7/00
CPC分类号： A61N2/002 , A61B18/14 , A61F7/007 , A61N2/006 , A61N7/02
摘要： The present invention is directed to methods and apparatus for modulation of the sympathetic-parasympathetic balance by application of heat, carotid and/or ocular message to reduce sympathetic tone or increase parasympathetic tone in a target muscle system to relieve a symptom of urinary hesitancy, shy bladder syndrome, DESD, urinary retention, or laryngeal spasm, as well as to monitor the efficacy of treatments for bladder conditions and to assist in the passage of medical devices through bodily sphincters as well as to treat congestive heart failure.
摘要翻译：本发明涉及通过应用热，颈动脉和/或眼睛信息来调节交感神经副交感神经平衡的方法和装置，以减少交感神经紧张或增加目标肌肉系统中的副交感神经紧张以减轻尿犹豫症状，害羞膀胱综合征，DESD，尿潴留或喉痉挛，以及监测治疗膀胱状况的功效，并帮助医疗器械通过身体括约肌以及治疗充血性心力衰竭。

26. 发明申请

US20080004679A1 NON-INVASIVE MODULATION OF THE AUTONOMIC NERVOUS SYSTEM 审中-公开
标题翻译：自主神经系统的非侵入性调节
公开(公告)号：US20080004679A1
公开(公告)日：2008-01-03
申请号：US11779543
申请日：2007-07-18
申请人： Morteza Naghavi , Mortaza Naghavi , Mojtaba Naghavi , Mark Johnson , Timothy O'Brien
发明人： Morteza Naghavi , Mortaza Naghavi , Mojtaba Naghavi , Mark Johnson , Timothy O'Brien
IPC分类号： A61F7/08
CPC分类号： A61N2/006 , A61B18/14 , A61F7/007 , A61N2/002 , A61N7/02
摘要： The present invention is directed to methods and apparatus for modulation of the sympathetic-parasympathetic balance by application of heat, carotid and/or ocular message to reduce sympathetic tone or increase parasympathetic tone in a target muscle system to relieve a symptom of urinary hesitancy, shy bladder syndrome, DESD, urinary retention, or laryngeal spasm, as well as to monitor the efficacy of treatments for bladder conditions and to assist in the passage of medical devices through bodily sphincters as well as to treat congestive heart failure.
摘要翻译：本发明涉及通过应用热，颈动脉和/或眼睛信息来调节交感神经副交感神经平衡的方法和装置，以减少交感神经紧张或增加目标肌肉系统中的副交感神经紧张以减轻尿犹豫症状，害羞膀胱综合征，DESD，尿潴留或喉痉挛，以及监测治疗膀胱状况的功效，并帮助医疗器械通过身体括约肌以及治疗充血性心力衰竭。

27. 发明申请

US20060165596A1 Method and apparatus for noninvasively evaluating endothelial function 审中-公开
标题翻译：非侵入性评估内皮功能的方法和装置
公开(公告)号：US20060165596A1
公开(公告)日：2006-07-27
申请号：US10525255
申请日：2003-08-22
申请人： Nachiket Kharalkar , Morteza Naghavi
发明人： Nachiket Kharalkar , Morteza Naghavi
IPC分类号： A61K49/00
CPC分类号： A61K49/0004 , A61K49/00 , A61K49/22
摘要： The present invention relates to assessing and measuring endothelial functions. A vasodilating stimulant is provided to a patient to stimulate hemodynamic activity in a selected region of the patient's body. In an embodiment, endothelial function may then be assessed by monitoring a change in a hemodynamic parameter at the selected region and assessing the patient's endothelial function based upon that monitoring. In a further embodiment, endothelial function may then be measured by monitoring a change in blood oxygen content at the selected region and assessing the patient's endothelial function based upon that monitoring. In yet a further embodiment, endothelial function may then be measured by monitoring a change in blood flow rate at the selected region and assessing the patient's endothelial function based upon said monitoring. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.
摘要翻译：本发明涉及评估和测量内皮功能。向患者提供血管舒张刺激剂以刺激患者身体的选定区域中的血液动力学活性。在一个实施方案中，然后可以通过监测所选区域的血液动力学参数的变化来评估内皮功能，并且基于该监测来评估患者的内皮功能。在另一个实施方案中，然后可以通过监测所选区域的血氧含量变化并基于该监测来评估患者的内皮功能来测量内皮功能。在另一个实施方案中，然后可以通过监测所选区域的血流速率的变化并且基于所述监测来评估患者的内皮功能来测量内皮功能。要强调的是，该摘要被提供以符合要求摘要的规则，这将允许搜索者或其他读者快速确定技术公开的主题。提交它的理解是，它不会用于解释或限制权利要求的范围或含义。

28. 发明公开

US20240115415A1 TONGUE RING AND OTHER TONGUE-ATTACHED DEVICES FOR PREVENTION OF SLEEP APNEA 审中-公开
公开(公告)号：US20240115415A1
公开(公告)日：2024-04-11
申请号：US18483051
申请日：2023-10-09
申请人： Morteza Naghavi
发明人： Morteza Naghavi
IPC分类号： A61F5/56
CPC分类号： A61F5/566
摘要： According to an aspect of the present invention, there is provided a tongue retaining device configured for reducing obstructive sleep apnea, comprising: a tongue piercing device; and one or more threads attached to the tongue piercing device and anchoring it to an anterior anchor point.

29. 发明公开

US20230352181A1 AI-ENABLED EXPEDITED RISK ASSESSMENT OF PATIENTS WITH CHEST PAIN 审中-公开
公开(公告)号：US20230352181A1
公开(公告)日：2023-11-02
申请号：US18167852
申请日：2023-02-11
申请人： Morteza Naghavi
发明人： Morteza Naghavi
IPC分类号： G16H50/30 , G16H30/40 , G16H40/20 , G16H50/20
CPC分类号： G16H50/30 , G16H30/40 , G16H40/20 , G16H50/20
摘要： Risk assessment systems and methods for patients with chest pain include, in some embodiments, an assessor, a computed tomography (CT) scanner, an electrocardiogram device for providing electrocardiogram data, and an enzyme analyzer for analyzing the patient’s blood. A computer enabled risk calculator categorizes the patients as low, intermediate, or high risk. The computer enabled risk calculator, using electrocardiogram data, blood analyzer, patient’s age, other risk factors, and history, automatically generates orders for low and intermediate risk patients to undergo a CT scan. A CAC analyzer provides a CAC score and/or a cardiovascular volumetry index based on CT scan results. A risk score based on electrocardiogram, blood analyzer and patient’s age, other risk factors and history of symptoms, the CAC score and/or cardiovascular volumetry index is generated. Patients that are automatically assessed as being very low risk based on the risk score are recommended for discharge from the emergency room.

30. 发明授权

US08246548B2 Ischemic conditioning for improved athletic performance 失效
标题翻译：缺血调理，提高运动能力
公开(公告)号：US08246548B2
公开(公告)日：2012-08-21
申请号：US13229738
申请日：2011-09-11
申请人： Morteza Naghavi , Albert Andrew Yen , Haider Ali Hassan , David S. Panthagani
发明人： Morteza Naghavi , Albert Andrew Yen , Haider Ali Hassan , David S. Panthagani
IPC分类号： A61B5/02 , A61B17/00
CPC分类号： A61B17/1355 , A61B5/01 , A61B5/022 , A61B5/14551 , A61B5/417 , A61B17/135 , G06F19/00
摘要： Methods for ischemic conditioning treatments of a chronic medical condition are provided. Baseline disease-related parameters of a patient with a chronic medical condition are measured. Ischemia is induced in the patient by occluding and releasing arterial flow in one or more extremities of the patient. Post-ischemia parameters in the patient are measured. The baseline and post-ischemia parameters are compared to provide an assessment of an ischemic conditioning treatment of a chronic medical condition. The repeated, scheduled delivery of ischemic conditioning provides a beneficial, therapeutic effect on the chronic medical condition. Also provided is a device for pulse oximetry during periods of absent or low pulsatile blood flow including an artificial pulse generator as well as the use of said device in assessment of ischemic conditioning.
摘要翻译：提供了慢性医疗条件的缺血调理治疗方法。测量患有慢性疾病的患者的基线疾病相关参数。通过在患者的一个或多个末端闭塞和释放动脉血流在患者中诱发缺血。测量患者的缺血后参数。比较基线和局部后缺血参数，以评估慢性疾病的缺血调理治疗。重复的，定期的缺血性调理递送对慢性疾病状况提供了有益的治疗效果。还提供了一种用于脉搏血氧饱和度测量的装置，其在包括人造脉冲发生器的缺血或低搏动血流期间以及所述装置在评估缺血调理中的用途。

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