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21. 发明授权

US07344549B2 Expandable cages for embolic filtering devices 有权
标题翻译：用于栓塞过滤装置的可膨胀笼
公开(公告)号：US07344549B2
公开(公告)日：2008-03-18
申请号：US10066314
申请日：2002-01-31
申请人： William J. Boyle , William J. Harrison , Benjamin C. Huter , Scott J. Huter , Paul F. Muller , John E. Papp
发明人： William J. Boyle , William J. Harrison , Benjamin C. Huter , Scott J. Huter , Paul F. Muller , John E. Papp
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/008
摘要： A self-expanding cage for use in conjunction with an embolic filtering device includes a circumferential member adapted to expand from an unexpanded position to a expanded position within the patient's body vessel. A proximal strut and distal strut are attached to the circumferential member to form the cage. A plurality of proximal and distal struts may be attached the circumferential member. Additionally, a second circumferential member can be attached to the first circumferential member. Each circumferential member can be connected by a single or a plurality of connecting struts. One embodiment of the cage utilizes a single wire to form to the cage. A delivery system attached to the single wire cage moves the cage and its associated filter element between the expanded and unexpanded positions through relative movement of the distal delivery system. This can be accomplished by either torquing the guide wire onto which the expandable cage is mounted or by longitudinally moving a tubular member which forms part of the delivery system longitudinally in relation to the guide wire.
摘要翻译：用于与栓塞过滤装置结合使用的自膨胀笼包括适于从未膨胀位置膨胀到患者体内容器内的扩张位置的周向构件。近端支柱和远侧支柱附接到周向构件以形成保持架。多个近端和远侧支柱可以附接在周向构件上。此外，第二周向构件可以附接到第一圆周构件。每个周向构件可以通过单个或多个连接支柱连接。笼的一个实施例使用单个线来形成笼。附接到单线笼的输送系统通过远端输送系统的相对运动使笼及其相关联的过滤元件在膨胀位置和未膨胀位置之间移动。这可以通过扭转其上安装有可膨胀笼的引导线或通过纵向移动相对于导丝纵向移动形成输送系统的一部分的管状构件来实现。

22. 发明授权

US07331973B2 Guide wire with embolic filtering attachment 有权
标题翻译：导丝与栓塞过滤附件
公开(公告)号：US07331973B2
公开(公告)日：2008-02-19
申请号：US10260718
申请日：2002-09-30
申请人： Douglas H. Gesswein , Wayne E. Cornish , Scott J. Huter , Benjamin C. Huter , John E. Papp
发明人： Douglas H. Gesswein , Wayne E. Cornish , Scott J. Huter , Benjamin C. Huter , John E. Papp
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/008
摘要： A separate deliverable embolic protection device filter that attaches to a helical coil at a distal end of a conventional guide, for use in a blood vessel when an interventional procedure is being performed to capture any embolic material which may be created and released into the bloodstream during the procedure. The device includes a filter assembly with a proximal end and a distal end, and a guide wire connector attached to the distal end of the filter assembly. The guide wire connector is able to couple with the helical coil of the guide wire. A restraining sheath placed over the filter assembly in a coaxial arrangement maintains the filter assembly in a collapsed position and delivers the filter assembly separately to the helical coil of the guide wire, and then the guide wire connector is joined to the helical coil. Alternatively, the guide wire can include a rotatable coil section forming a portion of the distal tip coil on the guide wire which is adapted to be coupled to the filter assembly. This arrangement allows the filter assembly to be rotatably mounted onto the guide wire.
摘要翻译：一种单独的可输送栓塞保护装置过滤器，其连接到常规引导件的远端处的螺旋线圈，用于血管中，当进行介入手术以捕获可能产生并释放到血流中的任何栓塞物质时步骤。该装置包括具有近端和远端的过滤器组件和连接到过滤器组件的远端的导丝连接器。导丝连接器能够与导丝的螺旋线圈耦合。以同轴布置放置在过滤器组件上方的限制护套将过滤器组件保持在折叠位置并将过滤器组件分别输送到导丝的螺旋线圈，然后导丝连接器连接到螺旋线圈。或者，引导线可以包括可旋转的线圈部分，其形成导丝上的远端尖端线圈的一部分，其适于联接到过滤器组件。这种布置允许过滤器组件可旋转地安装在导丝上。

23. 发明授权

US06599307B1 Filter device for embolic protection systems 有权
标题翻译：用于栓塞保护系统的过滤装置
公开(公告)号：US06599307B1
公开(公告)日：2003-07-29
申请号：US09919503
申请日：2001-07-31
申请人： Benjamin C. Huter , John E. Papp , Anuja Patel , John D. Whitfield
发明人： Benjamin C. Huter , John E. Papp , Anuja Patel , John D. Whitfield
IPC分类号： A61M2900
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/0065 , A61F2230/008
摘要： A system for enabling the insertion and removal of an embolic protection device, for capturing and retaining embolic debris which may be created during the performance of a therapeutic interventional procedure in a stenosed or occluded region of a blood vessel. The system, in an embodiment thereof, enables the device to be snap-fitted so as to engage the distal end of a guide wire, to provide a reference for positioning the device at a location distal to the interventional procedure site, and to enable an end of the device to be in tension, enabling a portion of the device to be in tension and another portion to be in compression, so as to assist in bending thereof in tortuous vasculature.
摘要翻译：一种能够插入和移除栓塞保护装置的系统，用于捕获和保留在血管的狭窄或阻塞区域中执行治疗介入手术期间可产生的栓塞碎片。该系统在其一个实施例中使得装置能够被卡扣配合以便与导丝的远端接合，以提供用于将装置定位在远离介入手术部位的位置处的参考，并使得能够所述装置的端部处于张紧状态，使得所述装置的一部分处于张紧位置，另一部分被压缩，从而有助于弯曲弯曲的脉管系统。

24. 发明授权

US06592606B2 Hinged short cage for an embolic protection device 有权
标题翻译：铰链短笼为栓塞保护装置
公开(公告)号：US06592606B2
公开(公告)日：2003-07-15
申请号：US09944633
申请日：2001-08-31
申请人： Benjamin C. Huter , Kevin M. Magrini , John E. Papp
发明人： Benjamin C. Huter , Kevin M. Magrini , John E. Papp
IPC分类号： A61M2900
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： A filtering device for capturing and removing embolic debris from a body vessel and a system for insertion and removal of the filtering device to facilitate an interventional procedure in a stenosed or occluded region of a body vessel. The filtering device is adapted to be expandable in the body vessel, allowing blood to pass therethrough while maintaining apposition with the body vessel wall and capturing embolic material released into the bloodstream during the interventional procedure, and to be collapsible to remove the captured embolic material from the body vessel. The filtering device includes a guide wire, an expandable cage assembly secured to the guide wire, filter material secured to the expandable cage assembly, and at least one hinge, the hinge allowing the expandable cage assembly to bend independent from the guide wire. The system, which includes a delivery sheath and filtering device, is adapted to retain the expandable cage assembly in a collapsed condition and deliver and deploy the filtering device at a location in the body vessel distal the treatment site.
摘要翻译：一种用于从身体容器捕获和去除栓塞碎片的过滤装置，以及用于插入和移除过滤装置的系统，以便于在体内容器的狭窄或阻塞区域进行介入手术。过滤装置适于在身体容器中扩张，允许血液通过其中，同时保持与身体血管壁的配合并且在介入手术过程中捕获释放到血流中的栓塞物质，并且可收缩以将捕获的栓塞材料从身体血管。过滤装置包括引导线，固定到引导线的可膨胀保持架组件，固定到可膨胀保持架组件的过滤材料以及至少一个铰链，铰链允许可膨胀笼组件独立于导丝弯曲。包括输送护套和过滤装置的系统适于将可膨胀笼组件保持在折叠状态，并将过滤装置输送并部署在远离治疗部位的体内血管的位置。

25. 发明申请

US20110245908A1 Mandrels Supporting Medical Devices During Processing of the Medical Devices 有权
标题翻译：在医疗器械加工过程中支持医疗器械的心轴
公开(公告)号：US20110245908A1
公开(公告)日：2011-10-06
申请号：US12752983
申请日：2010-04-01
申请人： John E. Papp
发明人： John E. Papp
IPC分类号： A61F2/82 , B23Q1/00 , B05D7/00
CPC分类号： B23Q3/062 , A61F2/82 , B05D1/002 , B05D1/02
摘要： An apparatus and method for applying a coating composition to a stent. A mandrel for supporting the stent has one or more drive pins and other supporting structure that loosely supports the stent, in an unstable position. The support permits freedom of movement of the stent relative to the mandrel to cause the stent to frequently re-position itself over the mandrel during a spraying process. When a coating composition is applied, the stent randomly or periodically moves about relative to the mandrel due to intermittent contact between the stent and the rotating mandrel and fluidic forces applied through the sprayed coating composition.
摘要翻译：一种将涂料组合物施用于支架的装置和方法。用于支撑支架的心轴具有在不稳定位置松散地支撑支架的一个或多个驱动销和其它支撑结构。该支撑件允许支架相对于心轴的移动自由度，使得支架在喷涂过程中自动频繁地重新定位在心轴上。当施加涂料组合物时，支架随着或周期性地相对于心轴移动，这是由于支架和旋转心轴之间的间歇接触以及通过喷涂组合物施加的流体力。

26. 发明授权

US07972356B2 Flexible and conformable embolic filtering devices 有权
标题翻译：灵活和适应性栓塞过滤装置
公开(公告)号：US07972356B2
公开(公告)日：2011-07-05
申请号：US11767784
申请日：2007-06-25
申请人： William J. Boyle , Benjamin C. Huter , Scott J. Huter , John E. Papp
发明人： William J. Boyle , Benjamin C. Huter , Scott J. Huter , John E. Papp
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0008 , A61F2230/008
摘要： A self-expanding cage for use in conjunction with an embolic filtering device includes one or more circumferential members adapted to expand from an unexpanded position to a expanded position within the patient's body vessel. At least one proximal strut and at least one distal strut are attached to the circumferential member to form the basket. The circumferential member may include a plurality of bending regions which enhance the ability of the circumferential member to move between the unexpanded and expanded positions. The proximal and distal struts can be attached to one of the bending regions. When two or more circumferential members are utilized, each member may be connected by a connecting strut which may be connected at a bending region. The connecting strut can be a straight segment or may have a non-linear shape to provide additional flexibility. The expandable cage can be mounted to a elongated member, such as a guide wire, and can be either permanently mounted or rotatably mounted thereto.
摘要翻译：用于与栓塞过滤装置结合使用的自膨胀笼包括适于从未膨胀位置扩展到患者体内容器内的扩张位置的一个或多个周向构件。至少一个近端支柱和至少一个远端支柱附接到周向构件以形成篮。周向构件可以包括多个弯曲区域，这些弯曲区域增强了圆周构件在未膨胀和膨胀位置之间移动的能力。近端和远端支柱可以附接到一个弯曲区域。当使用两个或更多个周向构件时，每个构件可以通过可在弯曲区域处连接的连接支柱连接。连接支柱可以是直线段，或者可以具有非线性形状以提供额外的灵活性。可扩展的保持架可以安装到诸如导丝的细长构件上，并且可以永久地安装或可旋转地安装在其上。

27. 发明授权

US07842064B2 Hinged short cage for an embolic protection device 有权
标题翻译：铰链短笼为栓塞保护装置
公开(公告)号：US07842064B2
公开(公告)日：2010-11-30
申请号：US11496854
申请日：2006-08-01
申请人： Benjamin C. Huter , Kevin M. Magrini , John E. Papp
发明人： Benjamin C. Huter , Kevin M. Magrini , John E. Papp
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： A filtering device for capturing and removing embolic debris from a body vessel and a system for insertion and removal of the filtering device to facilitate an interventional procedure in a stenosed or occluded region of a body vessel. The filtering device is adapted to be expandable in the body vessel, allowing blood to pass therethrough while maintaining apposition with the body vessel wall and capturing embolic material released into the bloodstream during the interventional procedure, and to be collapsible to remove the captured embolic material from the body vessel. The filtering device includes a guidewire, an expandable cage assembly secured to the guide wire, filter material secured to the expandable cage assembly, and at least one hinge, the hinge allowing the expandable cage assembly to bend independent from the guide wire. The system, which includes a delivery sheath and filtering device, is adapted to retain the expandable cage assembly in a collapsed condition and deliver and deploy the filtering device at a location in the body vessel distal the treatment site.
摘要翻译：一种用于从身体容器捕获和去除栓塞碎片的过滤装置，以及用于插入和移除过滤装置的系统，以便于在体内容器的狭窄或阻塞区域进行介入手术。过滤装置适于在身体容器中扩张，允许血液通过其中，同时保持与身体血管壁的配合并且在介入手术过程中捕获释放到血流中的栓塞物质，并且可收缩以将捕获的栓塞材料从身体血管。过滤装置包括导丝，固定到导丝的可膨胀保持架组件，固定到可膨胀笼组件的过滤材料以及至少一个铰链，该铰链允许可膨胀笼组件独立于导丝弯曲。包括输送护套和过滤装置的系统适于将可膨胀笼组件保持在折叠状态，并将过滤装置输送并部署在远离治疗部位的体内血管的位置。

28. 发明授权

US07780694B2 Intravascular device and system 有权
标题翻译：血管内装置和系统
公开(公告)号：US07780694B2
公开(公告)日：2010-08-24
申请号：US10680602
申请日：2003-10-06
申请人： Olin Palmer , Christopher T. Shen , Robert LaDuca , Larry Voss , Saypin Phonthalasa , John E. Papp , Stephen A. Morales , Coeta K. Peloquin , Charles R. Peterson , Anuja H. Patel
发明人： Olin Palmer , Christopher T. Shen , Robert LaDuca , Larry Voss , Saypin Phonthalasa , John E. Papp , Stephen A. Morales , Coeta K. Peloquin , Charles R. Peterson , Anuja H. Patel
IPC分类号： A61M29/00
CPC分类号： A61B17/221 , A61B2017/00526 , A61B2017/2212 , A61F2/01 , A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： A device for use in capturing or collecting debris found in blood vessels or other body lumens. The devices can be fabricated from a tube and include longitudinally and circumferentially extending members. The device can further embody structure that provides enhanced radial opening and angular resistance to collapse and structure for absorbing or modifying forces applied thereto by an operator.
摘要翻译：用于捕获或收集在血管或其他体腔内发现的碎屑的装置。装置可以由管制成并且包括纵向和周向延伸的构件。该装置可以进一步具有提供增强的径向开口和角度抵抗力的结构，该结构用于塌缩和结构，用于吸收或修改由操作者施加到其上的力。

29. 发明申请

US20100174355A1 DELIVERY AND RECOVERY SHEATHS FOR MEDICAL DEVICES 失效
标题翻译：医疗器械的交付和恢复
公开(公告)号：US20100174355A1
公开(公告)日：2010-07-08
申请号：US12724140
申请日：2010-03-15
申请人： William J. Boyle , Andy E. Denison , Benjamin C. Huter , Scott J. Huter , John E. Papp , Charles R. Peterson , Kent C.B. Stalker
发明人： William J. Boyle , Andy E. Denison , Benjamin C. Huter , Scott J. Huter , John E. Papp , Charles R. Peterson , Kent C.B. Stalker
IPC分类号： A61F2/84
CPC分类号： A61F2/013 , A61F2/95 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： A deployment control system provides controlled deployment of an embolic protection device which may include a guide wire, an expandable filter attached to the guide wire near its distal end, and a restraining sheath that maintains the expanded filter in a collapsed position. The deployment control system includes a torque control device which allows the physician to torque the guide wire into the patient's anatomy and a mechanism for preventing the guide wire from buckling as the restraining sheath is being retracted to deploy the expandable filter. A recovery control system for recovering the embolic protection device includes an inner catheter which extends within a lumen of an outer recovery sheath in a coaxial arrangement. A distal portion of the inner catheter extends beyond another recovery sheath during advancement of the recovery system into the vasculature. The recovery sheath can be advanced over the inner catheter to collapse the expandable filter. The proximal ends of the inner catheter and recovery sheath include handle portions having snap mechanisms which hold the components together as the recovery system is being advanced into the patient's vasculature.
摘要翻译：部署控制系统提供栓塞保护装置的可控部署，该栓塞保护装置可以包括引导线，在其远端附近附接到导丝的可扩张过滤器，以及将扩张过滤器保持在折叠位置的限制护套。部署控制系统包括扭矩控制装置，该扭矩控制装置允许医师将导丝扭转到患者的解剖结构中，以及用于防止导线在收缩护套以展开可膨胀过滤器时弯曲的机构。用于回收栓塞保护装置的恢复控制系统包括在同轴布置中在外部恢复护套的内腔内延伸的内导管。在将回收系统推进脉管系统期间，内导管的远端部分延伸超过另一恢复护套。恢复护套可以在内导管上推进以使可膨胀过滤器折叠。内导管和恢复护套的近端包括手柄部分，其具有卡扣机构，当回收系统进入患者的脉管系统时，该部件将部件保持在一起。

30. 发明申请

US20100049305A1 CONVERTIBLE DELIVERY SYSTEMS FOR MEDICAL DEVICES 审中-公开
标题翻译：医疗设备可交换系统
公开(公告)号：US20100049305A1
公开(公告)日：2010-02-25
申请号：US12545602
申请日：2009-08-21
申请人： William J. Boyle , Benjamin C. Huter , John E. Papp , Jack Sahakian , Richard S. Stack
发明人： William J. Boyle , Benjamin C. Huter , John E. Papp , Jack Sahakian , Richard S. Stack
IPC分类号： A61F2/00
CPC分类号： A61M25/0668 , A61M2025/0681
摘要： A delivery system for a medical device or other devices to be deployed within a biological body including a sheath having a longitudinal joint. The joint can be either resealable or non-resealable. The joint remains intact during delivery of the medical device, thereby facilitating accurate delivery of the medical device. During removal of the sheath, the joint is separated, thereby permitting the sheath to be peeled from the medical device while maintaining the position of the device. The delivery system allows a single operator to deploy the medical device and remove the sheath.
摘要翻译：用于医疗装置或其他装置的递送系统，其将部署在包括具有纵向接头的护套的生物体内。接头可以重新密封或不可重新密封。在医疗装置的输送期间关节保持完整，从而有助于医疗装置的准确输送。在去除护套期间，接头被分离，从而允许护套在保持装置的位置的同时从医疗装置剥离。输送系统允许单个操作者部署医疗装置并移除护套。

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