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    • 21. 发明授权
    • Vehicle seat housing apparatus
    • 车辆座椅设备
    • US09381836B2
    • 2016-07-05
    • US14006216
    • 2012-03-22
    • Makoto SawadaTadao KitagawaJunichi Yoshioka
    • Makoto SawadaTadao KitagawaJunichi Yoshioka
    • B60N2/30B60N2/36
    • B60N2/30B60N2/3011B60N2/305B60N2/3065B60N2/3079B60N2/36
    • A vehicle seat housing apparatus wherein a seat is swung back from a seatable position by a support mechanism and housed in a housing recess part such that the bottom is oriented upward, the housing recess part is formed on the floor behind the seat. The support mechanism includes a first support member, a second support member, a coupling shaft, and a folding mechanism. The first support member extends from either the floor or the housing recess part. The second support member extends from the bottom surface of the seat to the first support member. The coupling shaft couples the second support member to the first support member so as to allow back and forth swinging movement. The folding mechanism, when the seat is housed in the housing recess part, folds the first and second support members in a direction eliminating protrusion to the passenger compartment from the floor.
    • 一种车辆座椅收纳装置,其中座椅通过支撑机构从座椅位置摆回并容纳在壳体凹部中,使得底部朝向上方,壳体凹部形成在座椅后面的地板上。 支撑机构包括第一支撑构件,第二支撑构件,联接轴和折叠机构。 第一支撑构件从地板或壳体凹部延伸。 第二支撑构件从座的底表面延伸到第一支撑构件。 联接轴将第二支撑构件联接到第一支撑构件,以允许来回摆动。 折叠机构,当座椅容纳在壳体凹部中时,折叠第一和第二支撑构件的方向,以消除从地板到乘客舱的突出的方向。
    • 22. 发明申请
    • VEHICLE SEAT HOUSING APPARATUS
    • 车辆座椅外壳设备
    • US20140015273A1
    • 2014-01-16
    • US14006216
    • 2012-03-22
    • Makoto SawadaTadao KitagawaJunichi Yoshioka
    • Makoto SawadaTadao KitagawaJunichi Yoshioka
    • B60N2/30
    • B60N2/30B60N2/3011B60N2/305B60N2/3065B60N2/3079B60N2/36
    • A vehicle seat housing apparatus wherein a seat is swung back from a seatable position by a support mechanism and housed in a housing recess part such that the bottom is oriented upward, the housing recess part is formed on the floor behind the seat. The support mechanism includes a first support member, a second support member, a coupling shaft, and a folding mechanism. The first support member extends from either the floor or the housing recess part. The second support member extends from the bottom surface of the seat to the first support member. The coupling shaft couples the second support member to the first support member so as to allow back and forth swinging movement. The folding mechanism, when the seat is housed in the housing recess part, folds the first and second support members in a direction eliminating protrusion to the passenger compartment from the floor.
    • 一种车辆座椅收纳装置,其中座椅通过支撑机构从座椅位置摆回并容纳在壳体凹部中,使得底部朝向上方,壳体凹部形成在座椅后面的地板上。 支撑机构包括第一支撑构件,第二支撑构件,联接轴和折叠机构。 第一支撑构件从地板或壳体凹部延伸。 第二支撑构件从座的底表面延伸到第一支撑构件。 联接轴将第二支撑构件联接到第一支撑构件,以允许来回摆动。 折叠机构,当座椅容纳在壳体凹部中时,折叠第一和第二支撑构件的方向,以消除从地板到乘客舱的突出的方向。
    • 25. 发明申请
    • Ornament device, display device and electronic apparatus
    • 装饰装置,显示装置和电子装置
    • US20050254226A1
    • 2005-11-17
    • US11050925
    • 2005-02-04
    • Makoto SawadaShunji MimamiToshihiko Miyamura
    • Makoto SawadaShunji MimamiToshihiko Miyamura
    • F21V33/00G01D11/28
    • G01D11/28
    • An ornament device includes a light transmittable dye sensitizing solar battery having a pair of light transmittable plates and a solar battery element between the light transmittable plates, and a light-projecting member provided in the side of the battery opposite to the sunlight incident side thereof and projecting light to the battery. A display device further includes, in addition to the solar battery and light-projecting member of the ornament device, a liquid crystal portion provided in an area between the light transmittable plates being different from an area in which the solar battery element is provided between them, and the light-projecting member projects light both of the solar battery liquid and the liquid crystal portion. An electronics apparatus includes a case for housing all of the structural elements of the ornament device and the display device.
    • 装饰装置包括具有一对透光板的光透射性染料敏化太阳能电池和可透光板之间的太阳能电池元件,以及设置在电池的与阳光入射侧相对的侧面的投光构件, 将光投射到电池。 除了太阳能电池和装饰装置的投光构件之外,显示装置还包括设置在可透光板之间的区域中的液晶部分与在它们之间提供太阳能电池元件的区域不同 并且所述投光构件投射所述太阳能电池液体和所述液晶部分的光。 电子设备包括用于容纳装饰装置和显示装置的所有结构元件的壳体。
    • 29. 发明申请
    • TIMEPIECE DEVICE WITH MULTIPLE-HAND
    • 具有多个手柄的定时器件
    • US20110317525A1
    • 2011-12-29
    • US13164842
    • 2011-06-21
    • Makoto Sawada
    • Makoto Sawada
    • G04B19/06
    • G04B19/02G04C3/146
    • A timepiece device with multiple-hand which can be miniaturized and made thin as a whole has a configuration where a hour hand hour wheel positioned close to an hour hand to which a rotation movement of a 3rd motor via an hour hand gear train mechanism and a functional hand hour wheel positioned close to a functional hand to which a rotation movement of a 4th motor via a functional hand gear train mechanism are arranged on a front side of a support plate, and a 4th wheel positioned close to a second hand and a 2nd wheel positioned close to a minute hand are arranged on a rear side of the support plate.
    • 具有能够小型化,薄型化的多功能手表装置具有如下构造:时针轮位于接近时针的时刻,第三马达经由时针齿轮机构和 功能手轮位于靠近功能手的位置,第四马达通过功能手轮系机构的旋转运动布置在支撑板的前侧,第四轮位于靠近秒针和第二 靠近分针的车轮布置在支撑板的后侧。
    • 30. 发明授权
    • Polypeptides having brain-localizing activity and uses thereof
    • 具有脑定位活性的多肽及其用途
    • US07927811B2
    • 2011-04-19
    • US10567328
    • 2004-08-06
    • Makoto Sawada
    • Makoto Sawada
    • G01N33/53A61K38/08A61K38/12C07K17/02A61K49/00A61K47/00C12P21/02
    • C07K7/06A61K38/00C07K16/44
    • The present invention relates to polypeptides having a brain-localizing activity, molecules comprising these polypeptides, and pharmaceutical agents that confer brain-localizing activity. The present inventors are the first to reveal amino acid motif sequences involved in brain-localizing activity. Polypeptides that comprise such motif sequences and have brain localizing activity were discovered as follows: DNAs encoding polypeptides comprising random amino acid sequences were synthesized, and incorporated into a phage library. The phage library produced was used to screen for polypeptides having brain-localized activity, which yielded such several polypeptides. These polypeptides comprised common sequences, which lead to the successful discovery of amino acid motif sequences involved in brain-localizing activity. The polypeptides of the present invention comprising the motif sequences specifically bind to cerebrovascular endothelial cells, and induce a transcellular pathway that enables brain-specific targeting and transport of substances in the cerebral parenchyma, which was not possible prior to the present invention.
    • 本发明涉及具有脑定位活性的多肽,包含这些多肽的分子和赋予脑定位活性的药物。 本发明人首先揭示涉及脑定位活性的氨基酸序列序列。 包含这种基序序列并具有脑定位活性的多肽被发现如下:编码包含随机氨基酸序列的多肽的DNA,并并入噬菌体文库中。 产生的噬菌体文库用于筛选具有脑定位活性的多肽,其产生这样的多种多肽。 这些多肽包含通用序列,其导致成功发现涉及脑定位活性的氨基酸基序序列。 包含基序序列的本发明的多肽特异性结合脑血管内皮细胞,并诱导能够在脑实质中实现脑特异性靶向和运输物质的跨细胞途径,这在本发明之前是不可能的。