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21. 发明申请

US20050149077A1 Devices and methods for performing a vascular anastomosis 审中-公开
标题翻译：用于进行血管吻合的装置和方法
公开(公告)号：US20050149077A1
公开(公告)日：2005-07-07
申请号：US11059169
申请日：2005-02-16
申请人： Hanson Gifford , Lee Bolduc , Jeffrey Stein , Paul DiCesare , Peter Costa , William Holmes
发明人： Hanson Gifford , Lee Bolduc , Jeffrey Stein , Paul DiCesare , Peter Costa , William Holmes
IPC分类号： A61B17/00 , A61B17/064 , A61B17/11 , A61B17/115 , A61B17/12 , A61F2/00 , A61B17/08
CPC分类号： A61B17/12109 , A61B17/064 , A61B17/0643 , A61B17/11 , A61B17/115 , A61B17/12036 , A61B17/12045 , A61B17/12136 , A61B2017/00243 , A61B2017/0641 , A61B2017/1135 , A61B2017/12127 , A61F2002/30092 , A61F2210/0014
摘要： A system for performing an end-to-side vascular anastomosis including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis
摘要翻译：一种用于执行端对侧血管吻合的系统，包括吻合装置，应用仪器和用于进行血管吻合的方法。该系统适用于在冠状动脉旁路手术中进行血管移植物和升主动脉之间的吻合，特别是在进入CABG手术中。本发明的第一方面包括血管吻合缝。第一构造具有两部分：锚定构件，与目标血管壁形成附件和联接构件，与旁路移植血管形成附件。通过将连接构件插入到锚定构件中来完成吻合。第二种结构将锚定构件和联接构件的功能结合成一体式吻合钉。本发明的第二方面包括一种吻合装置，其具有内部凸缘，移植物容器在其上延伸，外部凸缘接触靶容器的外表面。由内外法兰施加的定制的压缩量夹住目标血管壁，并在移植血管和靶血管之间产生防漏密封。本发明的第三方面具有凸缘，移植管通过使移植物容器穿过凸缘而附接到该凸缘上，以及多个钉状构件，其将该移植物容器的凸缘和脱出端附接到靶血管形成吻合

22. 发明申请

US20050113906A9 MULTI-LUMEN PROSTHESIS SYSTEMS AND METHODS 有权
标题翻译：多元预测系统和方法
公开(公告)号：US20050113906A9
公开(公告)日：2005-05-26
申请号：US10693255
申请日：2003-10-24
申请人： Lee Bolduc , Andrew Chiang
发明人： Lee Bolduc , Andrew Chiang
IPC分类号： A61B17/064 , A61B17/068 , A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2220/0075
摘要： Systems and methods introduce and deploy a multi-lumen prosthesis into a blood vessel or hollow body organ. The prosthesis has a trunk divided by an internal septum, which defines, within at least a portion of the trunk interior, a multi-lumen flow channel configuration. A lumen extension component can be sized and configured to be fitted within at least one of the interior lumens to define an extended lumen.
摘要翻译：系统和方法将多腔假体引入和部署到血管或中空体器官中。假体具有被内部隔膜分隔的躯干，内部隔膜限定在主干内部的至少一部分内的多腔流动通道结构。管腔延伸部件的尺寸和构造可以安装在至少一个内部腔内，以限定延伸的内腔。

23. 发明申请

US20050090843A1 Catheter-based fastener implantation apparatus and methods 有权
标题翻译：基于导管的紧固件植入装置和方法
公开(公告)号：US20050090843A1
公开(公告)日：2005-04-28
申请号：US10692282
申请日：2003-10-23
申请人： Lee Bolduc
发明人： Lee Bolduc
IPC分类号： A61B17/064 , A61B17/068 , A61B17/08 , A61B17/122 , A61F2/06 , A61B17/00
CPC分类号： A61F2/07 , A61B17/064 , A61B17/068 , A61B17/122 , A61B2017/0647 , A61B2017/0649 , A61B2017/081 , A61F2/848 , A61F2/89 , A61F2002/065 , A61F2002/075 , A61F2220/0008 , A61F2220/0016 , A61F2230/0013
摘要： Systems and methods implant one or more fastening structure(s) in a targeted body region, e.g., within a hollow body organ or an intraluminal space. The fastening structure(s) are implanted to a vessel wall, and serve to secure a prosthesis within the hollow body organ or intraluminal space.
摘要翻译：系统和方法将一个或多个紧固结构植入目标身体区域，例如在中空身体器官或管腔内空间内。将紧固结构植入血管壁，并用于将假体固定在中空身体器官或腔内空间内。

24. 发明申请

US20050070992A1 Prosthesis systems and methods sized and configured for the receipt and retention of fasteners 审中-公开
标题翻译：假体系统和尺寸和配置用于收紧和保持紧固件的方法
公开(公告)号：US20050070992A1
公开(公告)日：2005-03-31
申请号：US10752435
申请日：2004-01-06
申请人： Lee Bolduc , Juan Parodi
发明人： Lee Bolduc , Juan Parodi
IPC分类号： A61B17/00 , A61B17/064 , A61B17/068 , A61F2/00 , A61F2/06 , A61F2/90
CPC分类号： A61B17/064 , A61B17/068 , A61B2017/003 , A61B2017/0646 , A61B2017/0649 , A61F2/064 , A61F2/07 , A61F2/89 , A61F2/90 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2250/0017 , A61F2250/0023 , A61F2250/0039
摘要： Systems and methods introduce and deploy prosthesis into a blood vessel or hollow body organ. The prosthesis is secured in place by fasteners, and includes a region or regions specially sized and configured to receive and retain the fasteners.
摘要翻译：系统和方法将假体引入和部署到血管或中空体器官中。假体通过紧固件固定就位，并且包括特别尺寸和构造成接收和保持紧固件的区域或区域。

25. 发明申请

US20050021132A1 Multi-lumen prosthesis systems and methods 有权
公开(公告)号：US20050021132A1
公开(公告)日：2005-01-27
申请号：US10693255
申请日：2003-10-24
申请人： Lee Bolduc , Andrew Chiang
发明人： Lee Bolduc , Andrew Chiang
IPC分类号： A61B17/064 , A61B17/068 , A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2220/0075
摘要： Systems and methods introduce and deploy a multi-lumen prosthesis into a blood vessel or hollow body organ. The prosthesis has a trunk divided by an internal septum, which defines, within at least a portion of the trunk interior, a multi-lumen flow channel configuration. A lumen extension component can be sized and configured to be fitted within at least one of the interior lumens to define an extended lumen.

26. 发明授权

US09848869B2 Prosthesis systems and methods 有权
公开(公告)号：US09848869B2
公开(公告)日：2017-12-26
申请号：US11981112
申请日：2007-10-31
申请人： Lee Bolduc , Juan Parodi
发明人： Lee Bolduc , Juan Parodi
IPC分类号： A61F2/82 , A61B17/064 , A61B17/068 , A61F2/07 , A61B17/00 , A61F2/06 , A61F2/90 , A61F2/89
CPC分类号： A61B17/064 , A61B17/068 , A61B2017/003 , A61B2017/0646 , A61B2017/0649 , A61F2/064 , A61F2/07 , A61F2/89 , A61F2/90 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2250/0017 , A61F2250/0023 , A61F2250/0039
摘要： Systems and methods for deploying a prosthesis in a tissue region in a hollow body organ or blood vessel provide a first prosthesis and a second prosthesis, each having a prosthetic material and a scaffold that supports the prosthetic material. The first prosthesis has a proximal neck region, and the second prosthesis has an end region. The end region is sized and configured to telescopically fit with the proximal neck region to form a composite prosthesis. The systems and methods manipulate a fastener attachment assembly to implant at least one fastener to secure the composite prosthesis in the tissue region.

27. 发明申请

US20150142016A1 MULTI-FIRE FASTENER DELIVERY SYSTEM AND METHOD 审中-公开
标题翻译：多功能紧固件输送系统及方法
公开(公告)号：US20150142016A1
公开(公告)日：2015-05-21
申请号：US14546766
申请日：2014-11-18
申请人： Lee Bolduc , Joshua Stafford
发明人： Lee Bolduc , Joshua Stafford
IPC分类号： A61B17/10
摘要： A prosthesis fastener applier includes a handle, a plurality of input controls, and a fastener delivery shaft. The handle contains a motor and a control circuit. The input controls are connected to the handle and communicatively connected to the control circuit. The fastener delivery shaft includes a fastener cartridge and a driver shaft. The fastener cartridge includes a plurality of internal threads configured to receive a plurality of helical fasteners in stacked relationship. The driver shaft is operatively connected to the motor, disposed within the fastener cartridge, and configured to pass through respective inner diameters of the helical fasteners. The control circuit is configured to control the motor in response to signals from one or more of the input controls to rotate the driver shaft to cause one or more of the helical fasteners to be advanced axially relative to the fastener cartridge.
摘要翻译：假体紧固件施加器包括手柄，多个输入控制器和紧固件输送轴。手柄包含电机和控制电路。输入控制连接到手柄并且通信地连接到控制电路。紧固件输送轴包括紧固件卡盘和驱动器轴。紧固件卡盘包括多个内螺纹，其构造成以堆叠关系接收多个螺旋紧固件。驾驶员轴可操作地连接到设置在紧固件卡盘内的马达，并且构造成穿过螺旋紧固件的相应的内径。控制电路被配置为响应于来自一个或多个输入控制器的信号来控制电动机以旋转驱动器轴，以使一个或多个螺旋紧固件相对于紧固件卡盘轴向前进。

28. 发明授权

US08690897B2 Devices, systems, and methods for prosthesis delivery and implantation, including the use of a fastener tool 有权
标题翻译：用于假体递送和植入的装置，系统和方法，包括使用紧固件工具
公开(公告)号：US08690897B2
公开(公告)日：2014-04-08
申请号：US12917842
申请日：2010-11-02
申请人： Lee Bolduc
发明人： Lee Bolduc
IPC分类号： A61B17/10 , B23P11/00
CPC分类号： A61F2/0095 , A61B17/00234 , A61B17/0401 , A61B17/068 , A61B17/105 , A61B17/3415 , A61B17/3468 , A61B2017/00292 , A61B2017/003 , A61B2017/0441 , A61B2017/0649 , A61B2017/0688 , A61B2090/3966 , A61F2/064 , A61F2/07 , A61F2/88 , A61F2/95 , A61F2/954 , A61F2002/067 , A61F2002/9511 , A61F2002/9517 , A61M25/0136 , Y10T29/49947 , Y10T29/53487 , Y10T29/53491
摘要： Devices, systems, and methods for implanting radially expandable prostheses in the body lumens rely on tacking or anchoring the prostheses with separately introduced fasteners. The prostheses may be self-expanding or balloon expandable, and may include a single lumen or more than one lumen. After initial placement, a fastener applier system is introduced within the expanded prostheses to deploy a plurality of fasteners to at least one prosthesis end. The fasteners are usually helical fasteners which are releasably restrained on the fastener driver, and are delivered by rotation of the fastener driver. The fasteners may be applied singly, typically in circumferentially spaced-apart patterns about the interior of at least one end of the prosthesis. A lumen extension or lumens may be coupled to the prosthesis to extend the reach of the prosthesis within the implantation site. Fasteners may also be applied to the lumen extensions.
摘要翻译：用于将可径向扩张的假体植入体腔内的装置，系统和方法依赖于使用单独引入的紧固件固定或固定假体。假体可以是自膨胀或气囊扩张的，并且可以包括单个腔或多于一个腔。在初始放置之后，将紧固件施加器系统引入到扩展的假体内以将多个紧固件展开到至少一个假体末端。紧固件通常是可释放地约束在紧固件驱动器上的螺旋紧固件，并且通过紧固件驱动器的旋转而被输送。紧固件可以单独施加，通常围绕假体的至少一端的内部沿周向间隔开的图案施加。管腔延伸部或内腔可以联接到假体以延长假体在植入部位内的距离。紧固件也可以应用于管腔延伸部。

29. 发明授权

US08685044B2 Systems and methods for attaching a prosthesis with a body lumen or hollow organ 有权
标题翻译：用于将假体附接到体腔或中空器官的系统和方法
公开(公告)号：US08685044B2
公开(公告)日：2014-04-01
申请号：US13495836
申请日：2012-06-13
申请人： Lee Bolduc , Phil Houle
发明人： Lee Bolduc , Phil Houle
IPC分类号： A61B17/10
CPC分类号： A61B17/10 , A61B17/064 , A61B17/068 , A61B17/08 , A61B17/083 , A61B17/115 , A61B2017/0649 , A61B2090/037 , A61F2/07 , A61F2/848 , A61F2/89 , A61F2002/072 , A61F2002/075 , A61F2220/0016 , A61F2250/0017
摘要： Systems and methods introduce and deploy prosthesis into a blood vessel or hollow body organ by intra-vascular access. The prosthesis is secured in place by fasteners which are implanted by an applier that is also deployed by intra-vascular access. The applier is configured to permit controlled, selective release of the fastener in a step that is independent of the step of implantation.
摘要翻译：系统和方法通过血管内通路将假体引入和部署到血管或中空身体器官中。假体通过紧固件固定在一起，该紧固件由还通过血管内通路部署的施放器植入。施加器构造成允许在独立于植入步骤的步骤中可控制选择性地释放紧固件。

30. 发明授权

US08092519B2 Endovascular aneurysm repair system 有权
标题翻译：血管内动脉瘤修复系统
公开(公告)号：US08092519B2
公开(公告)日：2012-01-10
申请号：US11166411
申请日：2005-06-24
申请人： Lee Bolduc
发明人： Lee Bolduc
IPC分类号： A61F2/06
CPC分类号： A61B17/10 , A61B17/064 , A61B17/068 , A61B17/072 , A61B2017/00292 , A61B2017/00778 , A61B2017/0646 , A61B2017/0649 , A61F2/06 , A61F2/064 , A61F2/07 , A61F2/848 , A61F2/90 , A61F2002/061 , A61F2002/065 , A61F2002/067 , A61F2002/075 , Y10S623/903
摘要： Method and apparatus for implanting radially expandable prostheses in the body lumens rely on tacking or anchoring of the prostheses with separately introduced fasteners. The prostheses may be self-expanding or balloon expandable. After initial placement, a fastener applier system is introduced within the expanded prostheses to deploy a plurality of fasteners at least one prosthesis end, usually as each end of the prosthesis. The fasteners are usually helical fasteners which are delivered from a helical track in the fastener applier by rotation with a rotator wire. The fasteners will be applied singly, typically in circumferentially spaced-apart patterns about the interior of each end of the prosthesis.
摘要翻译：用于将可径向扩张的假体植入体腔内的方法和装置依赖于使用单独引入的紧固件来修补或锚定假体。假体可以是自膨胀的或球囊可膨胀的。在初始放置之后，将紧固件施加器系统引入到扩展的假体内以将至少一个假体端部（通常作为假体的每个端部）展开多个紧固件。紧固件通常是螺旋形紧固件，其通过旋转线旋转而从紧固件施加器中的螺旋轨道输送。紧固件将单独施加，通常围绕假体的每个端部的内部沿周向间隔开的图案。

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