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21. 发明授权

US06900446B2 Charged particle beam irradiation equipment and control method thereof 失效
标题翻译：带电粒子束照射设备及其控制方法
公开(公告)号：US06900446B2
公开(公告)日：2005-05-31
申请号：US10287656
申请日：2002-11-05
申请人： Hiroshi Akiyama , Hiroshi Kubo , Kazuo Hiramoto
发明人： Hiroshi Akiyama , Hiroshi Kubo , Kazuo Hiramoto
IPC分类号： A61N5/10 , G01Q10/00 , G01Q60/00 , G01Q60/50 , G09G3/10 , G21K1/08 , G21K1/093 , G21K5/00 , H01J7/28 , H05H7/04
CPC分类号： H05H7/04 , A61N5/10 , A61N5/1043 , A61N2005/1087 , G21K1/093
摘要： A power supply for applying a voltage to a scanning electromagnet for deflecting a charged particle beam has a first power supply unit having no filter and a second power supply unit having a filter. When an irradiation position of the charged particle beam in an irradiation object is moved, the first power supply unit, namely a power supply unit having no filter, is used to apply the voltage to the scanning electromagnet, so that an exciting current flowing in the scanning electromagnet can be changed in a short time. Further, when the irradiation position of the charged particle beam is maintained, the second power supply is used to apply a voltage whose pulsating component was removed to the scanning electromagnet, so that the exciting current flowing in the scanning electromagnet can be controlled precisely. Consequently, the charged particle beam can be applied uniformly to the irradiation object and an irradiation time of the charged particle beam to the irradiation object can be curtailed.
摘要翻译：用于向扫描电磁体施加电压以使带电粒子束偏转的电源具有不具有滤波器的第一电源单元和具有滤波器的第二电源单元。当照射物体中的带电粒子束的照射位置移动时，使用第一电源单元即不具有滤波器的电源单元将电压施加到扫描电磁体，使得在扫描电磁铁可以在短时间内改变。此外，当保持带电粒子束的照射位置时，使用第二电源将脉冲分量除去的电压施加到扫描电磁体，使得可以精确地控制在扫描电磁体中流动的激励电流。因此，可以将带电粒子束均匀地施加到照射物体，并且可以减少带电粒子束对照射物体的照射时间。

22. 发明授权

US06881970B2 Charged particle beam irradiation equipment and control method thereof 失效
公开(公告)号：US06881970B2
公开(公告)日：2005-04-19
申请号：US10716472
申请日：2003-11-20
申请人： Hiroshi Akiyama , Hiroshi Kubo , Kazuo Hiramoto
发明人： Hiroshi Akiyama , Hiroshi Kubo , Kazuo Hiramoto
IPC分类号： A61N5/10 , G01Q10/00 , G01Q60/00 , G01Q60/50 , G09G3/10 , G21K1/08 , G21K1/093 , G21K5/00 , H01J7/28 , H05H7/04 , G01M23/00
CPC分类号： H05H7/04 , A61N5/10 , A61N5/1043 , A61N2005/1087 , G21K1/093
摘要： A power supply for applying a voltage to a scanning electromagnet for deflecting a charged particle beam has a first power supply unit having no filter and a second power supply unit having a filter. When an irradiation position of the charged particle beam in an irradiation object is moved, the first power supply unit, namely a power supply unit having no filter, is used to apply the voltage to the scanning electromagnet, so that an exciting current flowing in the scanning electromagnet can be changed in a short time. Further, when the irradiation position of the charged particle beam is maintained, the second power supply is used to apply a voltage whose pulsating component was removed to the scanning electromagnet, so that the exciting current flowing in the scanning electromagnet can be controlled precisely. Consequently, the charged particle beam can be applied uniformly to the irradiation object and an irradiation time of the charged particle beam to the irradiation object can be curtailed.

23. 发明授权

US06472834B2 Accelerator and medical system and operating method of the same 有权
标题翻译：加速器与医疗系统及操作方法相同
公开(公告)号：US06472834B2
公开(公告)日：2002-10-29
申请号：US09791697
申请日：2001-02-26
申请人： Kazuo Hiramoto , Hideaki Nishiuchi
发明人： Kazuo Hiramoto , Hideaki Nishiuchi
IPC分类号： H05H1304
CPC分类号： G21K5/04
摘要： The accelerator is a cyclic type accelerator having deflection electromagnets and four-pole electromagnets for making a charged particle beam circulate, a multi-pole electromagnet for generating a stability limit of resonance of betatron oscillation for the production of the charged particle beam, and a high frequency source for applying a high frequency electromagnetic field to the beam to move the beam to the outside of the stability limit, thus exciting resonance in the betatron oscillation. The high frequency source generates a sum signal of a plurality of AC signals of which the instantaneous frequencies change with respect to time, and of which the average values of the instantaneous frequencies with respect to time are different, and applies the sum signal via electrodes to the beam.
摘要翻译：加速器是具有用于使带电粒子束循环的偏转电磁体和四极电磁体的循环型加速器，用于产生用于产生带电粒子束的贝塔振荡的共振稳定极限的多极电磁体和高用于将高频电磁场施加到光束以将光束移动到稳定极限的外部的频率源，从而激发贝塔振荡中的谐振。高频源产生瞬时频率相对于时间变化的多个AC信号的和信号，并且其瞬时频率相对于时间的平均值不同，并且将经过电极的和信号施加到梁。

24. 发明授权

US06316776B1 Charged particle beam apparatus and method for operating the same 有权
标题翻译：带电粒子束装置及其操作方法
公开(公告)号：US06316776B1
公开(公告)日：2001-11-13
申请号：US09388437
申请日：1999-09-02
申请人： Kazuo Hiramoto , Hiroshi Akiyama , Koji Matsuda , Tetsuro Norimine , Masahiro Tadokoro
发明人： Kazuo Hiramoto , Hiroshi Akiyama , Koji Matsuda , Tetsuro Norimine , Masahiro Tadokoro
IPC分类号： H05H900
CPC分类号： A61N5/1042 , A61N5/1049 , A61N2005/1087 , A61N2005/1095
摘要： A method of irradiation with a charged particle beam and an irradiation apparatus wherein the charged particle beam supplied from an accelerator and extracted from the irradiation apparatus. The irradiation apparatus includes an electromagnet for scanning with the charged particle beam. The method includes the steps of stopping the extraction of the charged particle beam from the irradiation apparatus, changing an irradiation point of the charged particle beam by controlling the electromagnet under a condition when the extraction is stopped, and resuming the extraction of the charged particle beam from the irradiation apparatus after changing the irradiation point.
摘要翻译：一种带电粒子束照射的方法和照射装置，其中从加速器提供并从照射装置中提取的带电粒子束。照射装置包括用于用带电粒子束扫描的电磁体。该方法包括以下步骤：停止从照射装置提取带电粒子束，通过在提取停止的条件下控制电磁体来改变带电粒子束的照射点，并恢复提取带电粒子束改变照射点后从照射装置。

25. 发明授权

US08253113B2 Charged particle beam irradiation system and charged particle beam extraction method 有权
标题翻译：带电粒子束照射系统和带电粒子束提取方法
公开(公告)号：US08253113B2
公开(公告)日：2012-08-28
申请号：US12490696
申请日：2009-06-24
申请人： Hideaki Nishiuchi , Kazuyoshi Saito , Masahiro Tadokoro , Hiroshi Akiyama , Kazuo Hiramoto
发明人： Hideaki Nishiuchi , Kazuyoshi Saito , Masahiro Tadokoro , Hiroshi Akiyama , Kazuo Hiramoto
IPC分类号： G21K5/04
CPC分类号： A61N5/10 , A61N2005/1087 , H05H7/10 , H05H13/04
摘要： A charged particle beam irradiation system includes a synchrotron which accelerates an ion beam, an irradiation apparatus for irradiating an object with the ion beam introduced from the synchrotron, detection means for measuring an amount of accumulated charge of the ion beam that orbits in the synchrotron immediately before an extraction control period in an operating cycle of the synchrotron, and beam extraction control means for controlling extraction of the ion beam based on the measurement result of the accumulated beam charge amount so that extraction of a total amount of the ion beam is to be completed with an expiration of an extraction control time, the extraction control time representing a length of the extraction control period of the synchrotron and being set in advance.
摘要翻译：带电粒子束照射系统包括加速离子束的同步加速器，用于从同步加速器引入的离子束照射物体的照射装置，用于测量在同步加速器中轨道运动的离子束的累积电荷量的检测装置在同步加速器的操作循环中的提取控制期间之前，以及根据累积的光束电荷量的测量结果控制离子束的提取的光束提取控制装置，使得离子束的总量的提取为在提取控制时间到期时完成，提取控制时间表示同步加速器的提取控制周期的长度，并且预先设定。

26. 发明授权

US07838855B2 Charged particle irradiation system 有权
标题翻译：带电粒子照射系统
公开(公告)号：US07838855B2
公开(公告)日：2010-11-23
申请号：US12141603
申请日：2008-06-18
申请人： Yusuke Fujii , Hisataka Fujimaki , Kazuo Hiramoto
发明人： Yusuke Fujii , Hisataka Fujimaki , Kazuo Hiramoto
IPC分类号： A61N5/00 , H05H13/04 , G21K5/10
CPC分类号： A61N5/1048 , A61N2005/1087 , G21K5/04
摘要： A charged particle irradiation system that positions the beam at a target position to avoid irradiation of normal tissue includes an acceleration system 6 for extracting a charged particle beam, scanning magnets 24 and 25, and charged particle beam position monitors 26 and 27. On the basis of signals received from the charged particle beam position monitors 26 and 27, the control unit 70 calculates a beam position at a target position and then controls the scanning magnets 24 and 25 so that the charged particle beam is moved to a desired irradiation position at the target position. The control unit 70 corrects the value of an excitation current applied to each of the scanning magnets 24 and 25 on a specified cycle basis on the basis of information about the position and the angle of the charged particle beam.
摘要翻译：将光束定位在目标位置以避免正常组织照射的带电粒子照射系统包括用于提取带电粒子束的加速系统6，扫描磁体24和25以及带电粒子束位置监视器26和27.在此基础上从充电的粒子束位置监视器26和27接收的信号，控制单元70计算目标位置处的光束位置，然后控制扫描磁体24和25，使得带电粒子束移动到所需的照射位置目标位置。控制单元70基于关于带电粒子束的位置和角度的信息，在指定的周期基础上校正施加到每个扫描磁体24和25的激励电流的值。

27. 发明授权

US07709818B2 Particle beam irradiation apparatus and particle beam irradiation method 有权
标题翻译：粒子束照射装置和粒子束照射方法
公开(公告)号：US07709818B2
公开(公告)日：2010-05-04
申请号：US11239073
申请日：2005-09-30
申请人： Koji Matsuda , Kazuo Hiramoto , Kunio Moriyama
发明人： Koji Matsuda , Kazuo Hiramoto , Kunio Moriyama
IPC分类号： A61N5/10
CPC分类号： A61N5/1048 , A61N5/1043 , A61N5/1079 , A61N2005/1074 , A61N2005/1087
摘要： To ensure irradiation accuracy and safety, even when an irradiation device employing a different irradiation method is used, disclosed is herein a charged particle beam irradiation apparatus that irradiates an irradiation target with charged particle beams includes: a charged particle beam generator for generating the charged particle beams; a passive scattering irradiation device and a scanning irradiation device, both for irradiating the irradiation target with the charged particle beams; a beam transport system for transporting the charged particles beam extracted from the charged particle beam generator, to selected one of the two irradiation devices; and a central controller that modifies operating parameters on the charged particle beam generator, according to the irradiation method adopted for the selected irradiation device.
摘要翻译：为了确保照射精度和安全性，即使使用采用不同的照射方式的照射装置，在此公开了一种带电粒子束照射被照射靶的带电粒子束照射装置，包括：带电粒子束发生器，用于产生带电粒子梁; 被动散射照射装置和扫描照射装置，用于向照射目标照射带电粒子束; 用于将从带电粒子束发生器提取的带电粒子束传送到两个照射装置中的一个的光束传输系统; 以及根据所选择的照射装置采用的照射方法修改带电粒子束发生器的工作参数的中央控制器。

28. 发明申请

US20090039256A1 CHARGED PARTICLE IRRADIATION SYSTEM 有权
标题翻译：充电颗粒辐照系统
公开(公告)号：US20090039256A1
公开(公告)日：2009-02-12
申请号：US12141603
申请日：2008-06-18
申请人： Yusuke FUJII , Hisataka Fujimaki , Kazuo Hiramoto
发明人： Yusuke FUJII , Hisataka Fujimaki , Kazuo Hiramoto
IPC分类号： G01N23/00
CPC分类号： A61N5/1048 , A61N2005/1087 , G21K5/04
摘要： A charged particle irradiation system that positions the beam at a target position to avoid irradiation of normal tissue includes an acceleration system 6 for extracting a charged particle beam, scanning magnets 24 and 25, and charged particle beam position monitors 26 and 27. On the basis of signals received from the charged particle beam position monitors 26 and 27, the control unit 70 calculates a beam position at a target position and then controls the scanning magnets 24 and 25 so that the charged particle beam is moved to a desired irradiation position at the target position. The control unit 70 corrects the value of an excitation current applied to each of the scanning magnets 24 and 25 on a specified cycle basis on the basis of information about the position and the angle of the charged particle beam.
摘要翻译：将光束定位在目标位置以避免正常组织照射的带电粒子照射系统包括用于提取带电粒子束的加速系统6，扫描磁体24和25以及带电粒子束位置监视器26和27.在此基础上从充电的粒子束位置监视器26和27接收的信号，控制单元70计算目标位置处的光束位置，然后控制扫描磁体24和25，使得带电粒子束移动到所需的照射位置目标位置。控制单元70基于关于带电粒子束的位置和角度的信息，在指定的周期基础上校正施加到每个扫描磁体24和25的激励电流的值。

29. 发明授权

US07405407B2 Ion beam therapy system and its couch positioning method 有权
标题翻译：离子束治疗系统及其沙发定位方法
公开(公告)号：US07405407B2
公开(公告)日：2008-07-29
申请号：US11704372
申请日：2007-02-09
申请人： Kazuo Hiramoto , Hiroshi Akiyama , Yoshihiko Nagamine , Alfred Smith , Wayne Newhauser
发明人： Kazuo Hiramoto , Hiroshi Akiyama , Yoshihiko Nagamine , Alfred Smith , Wayne Newhauser
IPC分类号： H01L25/00 , A61N5/01 , A61N5/10
CPC分类号： A61N5/1049 , A61N5/1069 , A61N2005/1061 , A61N2005/1087
摘要： A therapy system using an ion beam, which can shorten the time required for positioning a couch (patient). The therapy system using the ion beam comprises a rotating gantry provided with an ion beam delivery unit including an X-ray tube. An X-ray detecting device having a plurality of X-ray detectors can be moved in the direction of a rotation axis of the rotating gantry. A couch on which a patient is lying is moved until a tumor substantially reaches an extension of an ion beam path in the irradiating unit. The X-ray tube is positioned on the ion beam path and the X-ray detecting device is positioned on the extension of the ion beam path. With rotation of the rotating gantry, both the X-ray tube emitting an X-ray and the X-ray detecting device revolve around the patient. The X-ray is emitted to the patient and detected by the X-ray detectors after penetrating the patient. Tomographic information of the patient is formed based on signals outputted from the X-ray detectors. Information for positioning the couch is generated by using the tomographic information.
摘要翻译：使用离子束的治疗系统，其可以缩短定位沙发（患者）所需的时间。使用离子束的治疗系统包括设置有包括X射线管的离子束输送单元的旋转台架。具有多个X射线检测器的X射线检测装置能够沿旋转机架的旋转轴线的方向移动。将患者躺在其上的沙发移动直到肿瘤基本上到达照射单元中的离子束路径的延伸。 X射线管位于离子束路径上，X射线检测装置位于离子束路径的延伸部上。通过旋转机架的旋转，发射X射线的X射线管和X射线检测装置都围绕患者转动。 X射线发射到患者身上，并在穿透患者后由X射线检测器进行检测。基于从X射线检测器输出的信号形成病人的层析信息。通过使用层析信息生成用于定位沙发的信息。

30. 发明申请

US20070252093A1 Ion beam delivery equipment and an ion beam delivery method 有权
标题翻译：离子束输送设备和离子束输送方法
公开(公告)号：US20070252093A1
公开(公告)日：2007-11-01
申请号：US11414204
申请日：2006-05-01
申请人： Hisataka Fujimaki , Koji Matsuda , Hiroshi Akiyama , Masaki Yanagisawa , Alfred Smith , Kazuo Hiramoto
发明人： Hisataka Fujimaki , Koji Matsuda , Hiroshi Akiyama , Masaki Yanagisawa , Alfred Smith , Kazuo Hiramoto
IPC分类号： G21K1/10 , A61N5/10
CPC分类号： A61N5/1048 , A61N2005/1087 , A61N2005/1095 , G21K1/10 , G21K5/04
摘要： The invention is intended to confirm whether the SOBP (spread-out Bragg peak) width is a desired value in real time during beam irradiation, and to improve safety in treatment. Ion beam delivery equipment comprises a beam generator including a synchrotron, an RMW (range modulation wheel) device for forming an SOBP width of an ion beam extracted from the beam generator, a beam delivery nozzle including a reference dose monitor and a main dose monitor which are installed respectively upstream and downstream of the RMW device in the direction of travel of the ion beam, and an SOBP width computing unit for computing the SOBP width of the ion beam, which is formed by the RMW device, based on values detected by both the reference dose monitor and the main dose monitor.
摘要翻译：本发明旨在确认在光束照射期间SOBP（展开布拉格峰）宽度是否是实时的期望值，并且提高了处理中的安全性。离子束输送设备包括一个光束发生器，它包括同步加速器，用于形成从光束发生器提取的离子束的SOBP宽度的RMW（范围调制轮）装置，包括参考剂量监测器和主剂量监测器分别安装在RMW装置的上游和下游沿着离子束行进的方向;以及SOBP宽度计算单元，用于根据由两个检测到的值计算由RMW装置形成的离子束的SOBP宽度参考剂量监测仪和主剂量监测仪。

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