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21. 发明申请

US20090120555A1 Novel amylolytic enzyme extracted from Bacillus sp. A 7-7 (DSM 12368) and washing and cleaning agents containing this novel amylolytic enzyme 有权
标题翻译：从芽孢杆菌提取的新型淀粉分解酶 A 7-7（DSM 12368）和含有该新型淀粉分解酶的洗涤和清洁剂
公开(公告)号：US20090120555A1
公开(公告)日：2009-05-14
申请号：US11975898
申请日：2007-10-22
申请人： Roland Breves , Karl-Heinz Maurer , Beatrix Kottwitz , Laura Polanyi-Bald , Angela Hellebrandt , Irmgard Schmidt , Regina Stehr , Angrit Weber
发明人： Roland Breves , Karl-Heinz Maurer , Beatrix Kottwitz , Laura Polanyi-Bald , Angela Hellebrandt , Irmgard Schmidt , Regina Stehr , Angrit Weber
IPC分类号： B29C65/00 , C12N1/20 , C12P1/00
CPC分类号： C12N9/2417 , C11D3/386 , Y02E50/17 , Y10T156/10 , Y10T156/1111
摘要： The invention relates to a novel amylolytic enzyme extracted from the microorganism Bacillus sp. A 7-7 (DSM 12368), to sufficiently similar proteins having an amylolytic function, to methods for the production thereof and to diverse fields of application for these proteins. In addition, the aforesaid can be further developed beyond the implemented fields of application for other technical purposes. The invention particularly relates to washing and cleaning agents containing amylolytic proteins of the aforementioned type, to methods for cleaning textiles or hard surfaces that involve the use of the amylolytic proteins or analogous agents, and to their use for cleaning textiles or hard surfaces.
摘要翻译：本发明涉及一种从微生物芽孢杆菌中提取的新型淀粉分解酶。 A7-7（DSM12368），具有具有淀粉分解功能的足够相似的蛋白质，其制备方法以及这些蛋白质的应用领域。此外，上述可以进一步开发超出其他技术目的的实施应用领域。本发明特别涉及含有上述类型的淀粉分解蛋白质的洗涤和清洁剂，涉及使用淀粉分解蛋白质或类似剂的纺织品或硬质表面的清洁方法及其用于清洁纺织品或硬质表面的用途。

22. 发明授权

US07320887B2 Alkaline protease variants 失效
标题翻译：碱性蛋白酶变体
公开(公告)号：US07320887B2
公开(公告)日：2008-01-22
申请号：US10836959
申请日：2004-04-30
申请人： Beatrix Kottwitz , Karl-Heinz Maurer , Roland Breves
发明人： Beatrix Kottwitz , Karl-Heinz Maurer , Roland Breves
IPC分类号： C12N9/54 , C12N15/57 , C12N15/74 , C11D3/386
CPC分类号： C12N9/54 , C11D3/38681
摘要： The invention relates to novel alkaline protease variants. These variants have, when enumerating the alkaline protease from Bacillus lentus, variations in amino acid position 61, positions 199 and/or 211 and, optionally, at least one modification that contributes to the stabilization of the molecule, said modification preferably being point mutations in positions 3 and/or 4. Particularly preferred are variants S3T/V41/G61A/V199] and S3T/V41/G61A/V1991/L211D of B. lentus alkaline protease. The invention also relates to the possible use of these enzymes in diverse technical processes and, in particular, to detergents and cleansers containing these novel alkaline protease variants.
摘要翻译：本发明涉及新的碱性蛋白酶变体。当列举来自迟缓芽孢杆菌的碱性蛋白酶时，这些变体具有氨基酸位置61，位置199和/或211的变化，和任选地至少一个有助于分子稳定化的修饰，所述修饰优选是点突变位置3和/或4.特别优选的是变形芽孢杆菌碱性蛋白酶的变体S3T / V41 / G61A / V199]和S3T / V41 / G61A / V1991 / L211D。本发明还涉及这些酶在不同技术过程中的可能用途，特别涉及含有这些新型碱性蛋白酶变体的洗涤剂和清洁剂。

23. 发明申请

US20050113273A1 Alkaline protease from bacillus gibsonii (DSM 14393) and washing and cleaning products comprising said alkaline protease 失效
标题翻译：碱性蛋白酶（DSM 14393）和含有所述碱性蛋白酶的洗涤和清洁产品
公开(公告)号：US20050113273A1
公开(公告)日：2005-05-26
申请号：US10872162
申请日：2004-06-18
申请人： Angrit Weber , Angela Hellebrandt , Susanne Wieland , Karl-Heinz Maurer , Beatrix Kottwitz
发明人： Angrit Weber , Angela Hellebrandt , Susanne Wieland , Karl-Heinz Maurer , Beatrix Kottwitz
IPC分类号： G03C11/24 , A23C9/12 , A23J3/34 , A61K8/64 , A61K8/66 , A61K8/72 , A61K8/99 , A61Q5/02 , A61Q19/00 , A61Q19/10 , C07K19/00 , C11D3/386 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/54 , C12N15/09 , C12N15/57 , C12P21/06 , C12Q1/37 , C12R1/10 , D06L1/20 , D06L3/11 , C07H21/04 , C12N9/16 , C12N15/74
CPC分类号： A61K8/64 , A61K8/66 , A61Q5/02 , A61Q19/10 , C11D3/386 , C12N9/54
摘要： Described herein are novel alkaline proteases of the subtilisin type from Bacillus gibsonii (DSM 14393), and sufficiently related proteins and derivatives thereof. Also described are washing and cleaning products with this novel alkaline protease of the subtilisin type, sufficiently related proteins and derivatives thereof, corresponding washing and cleaning methods and the use thereof in washing and cleaning products and further possible technical use.
摘要翻译：本文描述了来自芽孢杆菌（DSM 14393）的枯草杆菌蛋白酶类型的新碱性蛋白酶，以及足够相关的蛋白质及其衍生物。还描述了使用这种新型的枯草杆菌蛋白酶型碱性蛋白酶，足够相关的蛋白质及其衍生物，相应的洗涤和清洁方法以及其在洗涤和清洁产品中的用途以及进一步可能的技术用途的洗涤和清洁产品。

24. 发明申请

US20050003985A1 Alkaline protease variants 失效
标题翻译：碱性蛋白酶变体
公开(公告)号：US20050003985A1
公开(公告)日：2005-01-06
申请号：US10836959
申请日：2004-04-30
申请人： Beatrix Kottwitz , Karl-Heinz Maurer , Roland Breves
发明人： Beatrix Kottwitz , Karl-Heinz Maurer , Roland Breves
IPC分类号： A23K1/165 , A23C19/032 , A23L1/00 , A61K8/00 , A61K8/66 , A61K8/72 , A61Q19/10 , C11D3/386 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/54 , C12N15/09 , C12N15/57 , C12P21/06 , C12Q1/37 , C14C11/00 , D06L4/40 , D06M16/00 , D06M101/12 , C07H21/04 , C12N15/74
CPC分类号： C12N9/54 , C11D3/38681
摘要： The invention relates to novel alkaline protease variants. These variants have, when enumerating the alkaline protease from Bacillus lentus, variations in amino acid position 61, positions 199 and/or 211 and, optionally, at least one modification that contributes to the stabilization of the molecule, said modification preferably being point mutations in positions 3 and/or 4. Particularly preferred are variants S3T/V41/G61A/V199] and S3T/V41/G61A/V1991/L211D of B. lentus alkaline protease. The invention also relates to the possible use of these enzymes in diverse technical processes and, in particular, to detergents and cleansers containing these novel alkaline protease variants.
摘要翻译：本发明涉及新的碱性蛋白酶变体。当列举来自迟缓芽孢杆菌的碱性蛋白酶时，这些变体具有氨基酸位置61，位置199和/或211的变化，和任选地至少一个有助于分子稳定化的修饰，所述修饰优选是点突变位置3和/或4.特别优选的是变形芽孢杆菌碱性蛋白酶的变体S3T / V41 / G61A / V199]和S3T / V41 / G61A / V1991 / L211D。本发明还涉及这些酶在不同技术过程中的可能用途，特别涉及含有这些新型碱性蛋白酶变体的洗涤剂和清洁剂。

25. 发明授权

US06417151B1 Activators for peroxide compounds in detergents and cleaning agents 失效
标题翻译：过氧化物在洗涤剂和清洁剂中的活化剂
公开(公告)号：US06417151B1
公开(公告)日：2002-07-09
申请号：US09402404
申请日：1999-10-04
申请人： Marita Grothus , Albrecht Weiss , Beatrix Kottwitz , Ulrich Pegelow , Guenter Uphues , Inken Prueser
发明人： Marita Grothus , Albrecht Weiss , Beatrix Kottwitz , Ulrich Pegelow , Guenter Uphues , Inken Prueser
IPC分类号： C11D300
CPC分类号： C11D3/38654 , C11D3/3927 , D06L4/12
摘要： A detergent or disinfectant composition comprising is presented having 0.5 to 10 percent by weight of an activator compound which under perhydrolysis conditions forms a percarboxylic acid, and releases a leaving group capable of being used as a substrate for enzymes, and up to 50 percent by weight of a peroxygen compound. The composition increases the oxidation of peroxide compounds in oxidation, bleaching, detergent, cleaning and disinfecting solutions, especially at low temperatures.
摘要翻译：含有洗涤剂或消毒剂组合物的组合物含有0.5至10重量％的活化剂化合物，其在过水解条件下形成过羧酸，并释放出能够用作酶底物的离去基团，最高达50重量％的过氧化合物。该组合物增加了氧化，漂白，洗涤剂，清洁和消毒溶液中过氧化物化合物的氧化，特别是在低温下。

26. 发明授权

US06380147B1 Detergents containing amylase and protease 失效
标题翻译：含有淀粉酶和蛋白酶的洗涤剂
公开(公告)号：US06380147B1
公开(公告)日：2002-04-30
申请号：US09701645
申请日：2001-02-09
申请人： Horst-Dieter Speckmann , Beatrix Kottwitz , Karl-Heinz Maurer , Christian Nitsch
发明人： Horst-Dieter Speckmann , Beatrix Kottwitz , Karl-Heinz Maurer , Christian Nitsch
IPC分类号： C11D300
CPC分类号： C11D3/386
摘要： The invention relates to detergents characterized in that they contain &agr;-amylase from Bacillus amyloliquefaciens and protease from Bacillus lentus, optionally modified by genetic engineering, in addition to our usual ingredients compatible with said enzymes.
摘要翻译：本发明涉及洗涤剂，其特征在于除了我们与所述酶相容的常规成分之外，它们还包含来自解淀粉芽孢杆菌的α-淀粉酶和来自迟缓芽孢杆菌的蛋白酶，任选经遗传工程修饰。

27. 发明授权

US06313081B1 Detergents comprising cellulases 失效
标题翻译：含有纤维素酶的洗涤剂
公开(公告)号：US06313081B1
公开(公告)日：2001-11-06
申请号：US08945574
申请日：1998-02-27
申请人： Hermanus Bernardus Maria Lenting , Rudolf Franciscus Wilhelmus Cornelis Van Beckhoven , Karl-Heinz Maurer , Beatrix Kottwitz , Albrecht Weiss , Pieter Van Solingen
发明人： Hermanus Bernardus Maria Lenting , Rudolf Franciscus Wilhelmus Cornelis Van Beckhoven , Karl-Heinz Maurer , Beatrix Kottwitz , Albrecht Weiss , Pieter Van Solingen
IPC分类号： C11D3386
CPC分类号： C12N9/2437 , C12Y302/01004 , D06M2200/20
摘要： A laundry detergent composition comprises a cellulase having a ratio of tensile strength loss to antipilling properties of less than 1. A method of laundering cotton-containing fabrics with the composition is also disclosed.
摘要翻译：衣物洗涤剂组合物包含具有小于1的拉伸强度损失与抗起绒性能的比率的纤维素酶。还公开了对含有该组合物的含棉织物进行洗涤的方法。

28. 发明授权

US5691295A Detergent compositions 失效
标题翻译：洗涤剂组合物
公开(公告)号：US5691295A
公开(公告)日：1997-11-25
申请号：US373818
申请日：1995-01-17
申请人： Karl-Heinz Maurer , Winfried Pochandke , Beatrix Kottwitz , Jorg Poethkow , Albrecht Weiss , Irmgard Schmidt , Horst Upadek
发明人： Karl-Heinz Maurer , Winfried Pochandke , Beatrix Kottwitz , Jorg Poethkow , Albrecht Weiss , Irmgard Schmidt , Horst Upadek
IPC分类号： C11D3/386 , C12N9/54
CPC分类号： C11D3/386 , C12N9/54
摘要： A laundry detergent for washing fabrics composed of proteinogenic fibers is comprised of at least one surfactant and a proteolytically active amount of a protease having a keratinase/caseinase activity ratio of less than about 0.80.
摘要翻译：由蛋白质纤维组成的用于洗涤织物的衣物洗涤剂由至少一种表面活性剂和蛋白水解活性量的蛋白酶组成，其中角蛋白酶/酪蛋白酶活性比小于约0.80。

29. 发明授权

US5273674A 2,5-diacyloxy-2,5-dihydrofuran activators for inorganic per compounds 失效
标题翻译： 2,5-二酰氧基-2,5-二氢呋喃活化剂，用于无机化合物
公开(公告)号：US5273674A
公开(公告)日：1993-12-28
申请号：US952908
申请日：1992-11-17
申请人： Beatrix Kottwitz , Thomas Merz , Rudolf Lehmann
发明人： Beatrix Kottwitz , Thomas Merz , Rudolf Lehmann
IPC分类号： C11D3/39 , A61K31/19 , C11D3/395 , C11D7/54 , D06L3/02
CPC分类号： C11D3/391
摘要： 2,5-diacyloxy-2,5-dihydrofurans corresponding to formula (I) ##STR1## wherein R is a C.sub.1 -C.sub.8 alkyl radical or a phenyl radical are useful as activators for inorganic per compounds in oxidizing, cleaning or disinfecting solutions.
摘要翻译： PCT No.PCT / EP91 / 00864 Sec。 371日期：1992年11月17日 102（e）日期：1992年11月17日PCT 1991年5月8日PCT PCT。出版物WO91 / 18082 日本1991年11月28日对应于式（I）的2,5-二酰氧基-2,5-二氢呋喃其中R是C1-C8烷基或苯基可用作无机化合物的活化剂氧化，清洁或消毒溶液。

30. 发明授权

US07985570B2 Alkaline proteases and detergents and cleaners comprising these alkaline proteases 有权
标题翻译：包含这些碱性蛋白酶的碱性蛋白酶和洗涤剂和清洁剂
公开(公告)号：US07985570B2
公开(公告)日：2011-07-26
申请号：US12718086
申请日：2010-03-05
申请人： Susanne Wieland , Karl-Heinz Maurer , Beatrix Kottwitz , Frank Niehaus , Patrick Lorenz
发明人： Susanne Wieland , Karl-Heinz Maurer , Beatrix Kottwitz , Frank Niehaus , Patrick Lorenz
IPC分类号： C12N9/48 , C11D3/386
CPC分类号： C12N9/52 , C11D3/38609 , C11D3/38618
摘要： The present application relates to two novel proteases (SEQ ID NO: 4 and 7) which are similar to one another. The DNA of the two proteases, was obtained from soil samples, and C-terminally deleted, producing proteolytically active fragments thereof (SEQ ID NO: 5 and 8). The invention also provides all alkaline proteases similar at least to 90% to SEQ ID NO: 4 or to 87.5% to SEQ ID NO: 7, and those which can be summarized under a consensus sequence (SEQ ID NO: 9) derived from SEQ ID NO: 4 and 7. Furthermore, it relates to all nucleic acids which have a homology of at least 85% identity to the associated nucleic acids (SEQ ID NO: 3 and 6) or the fragments concerned. Furthermore, it defines technical possibilities of use for these proteases and especially describes their use in detergents and cleaners.
摘要翻译：本申请涉及两个彼此相似的新型蛋白酶（SEQ ID NO：4和7）。两种蛋白酶的DNA从土壤样品获得，并且C末端缺失，产生其蛋白水解活性片段（SEQ ID NO：5和8）。本发明还提供了类似于SEQ ID NO：4至少90％或SEQ ID NO：7至87.5％的所有碱性蛋白酶，以及可归纳于SEQ ID NO：7衍生的共有序列（SEQ ID NO：9）此外，它涉及与相关核酸（SEQ ID NO：3和6）或相关片段具有至少85％同一性的同源性的所有核酸。此外，它定义了用于这些蛋白酶的技术可能性，特别描述了它们在洗涤剂和清洁剂中的应用。

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