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21. 发明授权

US07918848B2 Tissue welding and cutting apparatus and method 有权
标题翻译：组织焊接和切割设备及方法
公开(公告)号：US07918848B2
公开(公告)日：2011-04-05
申请号：US11090330
申请日：2005-03-25
申请人： Liming Lau , Arnold M. Escano , Jerry Jarrard , Sam Ho , Ryan C. Abbott , Arthur M. Lin , Jesse McQuiston , Peter L. Callas , Geoffrey H. Willis , Michael C. Stewart , Kimberly D. Barkman , Joseph N. Lamberti , Kenny L. Dang
发明人： Liming Lau , Arnold M. Escano , Jerry Jarrard , Sam Ho , Ryan C. Abbott , Arthur M. Lin , Jesse McQuiston , Peter L. Callas , Geoffrey H. Willis , Michael C. Stewart , Kimberly D. Barkman , Joseph N. Lamberti , Kenny L. Dang
IPC分类号： A61B18/04
CPC分类号： A61B18/085 , A61B17/29 , A61B18/082 , A61B18/1445 , A61B90/03 , A61B2017/00084 , A61B2017/00353 , A61B2017/00504 , A61B2017/2912 , A61B2017/2936 , A61B2017/2945 , A61B2017/3445 , A61B2018/00089 , A61B2018/00601 , A61B2018/00607 , A61B2018/00619 , A61B2018/1432
摘要： A surgical apparatus and methods for severing and welding tissue, in particular blood vessels, include a pair of relatively movable jaws at a distal end of an elongated shaft. A first heating element on one of the jaws is adapted to heat up to a first temperature and form a welded region within the tissue, while a second heating element on one of the jaws is adapted to heat up to a second temperature and sever the tissue within the welded region. A force-limiting mechanism is provided to limit the pressure applied to the tissue by the jaws to ensure that the tissue is severed and the ends effectively welded within a short amount of time.
摘要翻译：用于切断和焊接组织，特别是血管的手术装置和方法包括在细长轴的远端处的一对相对可动的钳口。其中一个钳口上的第一加热元件适于加热至第一温度并在组织内形成焊接区域，而其中一个钳口上的第二加热元件适于加热至第二温度并切断组织在焊接区域内。提供力限制机构以限制由钳口施加到组织的压力，以确保组织被切断并且端部在短时间内有效地焊接。

22. 发明授权

US06808534B1 Collapsible jacket guard 失效
标题翻译：可折叠夹克护卫
公开(公告)号：US06808534B1
公开(公告)日：2004-10-26
申请号：US10023027
申请日：2001-12-17
申请人： Arnold M. Escano
发明人： Arnold M. Escano
IPC分类号： A61F206
CPC分类号： A61F2/07 , A61F2/89 , A61F2/954 , A61F2/958 , A61F2002/065 , A61F2002/075 , A61F2230/0054
摘要： An improved reduced diameter intraluminal grafting system capable of deploying a bifurcated graft into a bifurcated vessel is described. The system having a pliable jacket guard configured to ensure atraumatic delivery and deployment of the bifurcated graft. The bifurcated graft is comprised of a main tubular member and two tubular legs with attachment systems configured into each of the three ends of the graft. The bifurcated graft along with the mechanisms required to position and attach the bifurcated graft fit within a single delivery catheter for intraluminal delivery. The bifurcated graft, positioning mechanisms and attaching mechanisms are configured such that a small diameter delivery catheter can be utilized. The methods of positioning and attaching the bifurcated graft are also described.
摘要翻译：描述了能够将分叉移植物部署到分叉血管中的改进的减小的腔内植入系统。该系统具有柔软的护套护罩，其构造成确保分叉移植物的无创性递送和展开。分叉移植物包括主管状构件和两个管状腿，其中附接系统构造成移植物的三个端部中的每一个。分叉移植物以及将分叉移植物定位和连接所需的机制适合于用于腔内递送的单个输送导管。分叉移植物，定位机构和连接机构被构造成可以使用小直径输送导管。还描述了定位和连接分叉移植物的方法。

23. 发明授权

US06729356B1 Endovascular graft for providing a seal with vasculature 失效
标题翻译：血管内移植物用于提供脉管系统的密封
公开(公告)号：US06729356B1
公开(公告)日：2004-05-04
申请号：US09559681
申请日：2000-04-27
申请人： Steven G. Baker , Tamara L. Trayer , Arnold M. Escano , Mark LeMere , Elizabeth A. McDermott
发明人： Steven G. Baker , Tamara L. Trayer , Arnold M. Escano , Mark LeMere , Elizabeth A. McDermott
IPC分类号： D03D300
CPC分类号： A61F2/07 , A61B17/12022 , A61B17/12118 , A61B17/12136 , A61B17/1219 , A61B2017/1205 , A61F2/848 , A61F2/89 , A61F2002/075 , A61F2002/077 , A61F2230/0067 , A61F2250/0003 , D03D3/02 , D03D3/08 , D03D27/00 , Y10S623/921
摘要： A graft provided with a flexible sealing member to substantially prevent blood from leaking between the graft a lumen into which the graft is placed. In one embodiment, the flexible sealing member may be pressed against the vascular wall by an outwardly biased spring means attached to the sealing member. In other embodiments, the sealing member may be self-positioning upon deployment of the graft. The sealing member also may be formed into the shape of a toroid, which may be filled with thrombogenic material causing blood permeating into the toroid-shaped space to coagulate therein and hold the sealing member in place. It is also contemplated that the sealing member be formed from tufts of frayed yarn protruding circumferentially from the outer surface of the graft. A method of manufacturing such tufted yarn sealing members is also disclosed.
摘要翻译：移植物设置有柔性密封构件，以基本上防止血液在移植物之间泄漏，移植物被置于其中。在一个实施例中，柔性密封构件可以通过附接到密封构件的向外偏置的弹簧装置压靠在血管壁上。在其它实施例中，密封构件可以在移植物展开时自我定位。密封构件也可以形成为环形的形状，其可以填充血栓形成材料，导致血液渗透到环形空间中以凝结在其中并将密封构件保持在适当位置。还可以设想，密封构件由从移植物的外表面周向突出的磨粒纱线形成。还公开了这种簇绒纱线密封件的制造方法。

24. 发明申请

US20130018373A1 APPARATUS AND METHOD FOR REGULATING TISSUE WELDER JAWS 有权
公开(公告)号：US20130018373A1
公开(公告)日：2013-01-17
申请号：US13549367
申请日：2012-07-13
申请人： Liming Lau , Arthur M. Lin , Samuel Ho , Ryan C. Abbott , Kenny L. Dang , Jesse McQuiston , Arnold M. Escano , Jerry Jarrard
发明人： Liming Lau , Arthur M. Lin , Samuel Ho , Ryan C. Abbott , Kenny L. Dang , Jesse McQuiston , Arnold M. Escano , Jerry Jarrard
IPC分类号： A61B18/14
CPC分类号： A61B18/085 , A61B17/29 , A61B18/082 , A61B18/1445 , A61B90/03 , A61B2017/00084 , A61B2017/00353 , A61B2017/00504 , A61B2017/2912 , A61B2017/2936 , A61B2017/2945 , A61B2017/3445 , A61B2018/00089 , A61B2018/00601 , A61B2018/00607 , A61B2018/00619 , A61B2018/1432
摘要： A surgical apparatus and methods for severing and welding tissue, in particular blood vessels. The apparatus includes an elongated shaft having a pair of relatively movable jaws at a distal end thereof. A first heating element on one of the jaws is adapted to heat up to a first temperature and form a welded region within the tissue, while a second heating element on one of the jaws is adapted to heat up to a second temperature and sever the tissue within the welded region. The first and second heating elements may be provided on the same or opposite jaws. A control handle provided on the proximal end of the elongated shaft includes controls for opening and closing the jaws, and may include an actuator for sending current through the first and second heating elements. The first and second heating elements may be electrically connected in series, and the first heating element may be bifurcated such that it conducts about one half of the current as the second heating element. A force-limiting mechanism provided either within the control handle, in the elongated shaft, or at the jaws limits the pressure applied to the tissue by the jaws to ensure that the tissue is severed and the ends effectively welded within a short amount of time.

25. 发明授权

US08197472B2 Tissue welding and cutting apparatus and method 有权
标题翻译：组织焊接和切割设备及方法
公开(公告)号：US08197472B2
公开(公告)日：2012-06-12
申请号：US11090750
申请日：2005-03-25
申请人： Liming Lau , Arnold M. Escano , Jerry Jarrard , Samuel Ho , Ryan C. Abbott , Arthur M. Lin , Jesse McQuiston , Kelly L. Dang
发明人： Liming Lau , Arnold M. Escano , Jerry Jarrard , Samuel Ho , Ryan C. Abbott , Arthur M. Lin , Jesse McQuiston , Kelly L. Dang
IPC分类号： A61B18/04
CPC分类号： A61B18/085 , A61B17/29 , A61B18/1445 , A61B90/03 , A61B2017/00084 , A61B2017/00353 , A61B2017/00504 , A61B2017/2912 , A61B2017/2936 , A61B2017/2945 , A61B2017/3445 , A61B2018/1432
摘要： A surgical apparatus and methods for severing and welding tissue, in particular blood vessels. The apparatus includes an elongated shaft having a pair of relatively movable jaws at a distal end thereof. A first heating element on one of the jaws is adapted to heat up to a first temperature and form a welded region within the tissue, while a second heating element on one of the jaws is adapted to heat up to a second temperature and sever the tissue within the welded region. The first and second heating elements may be provided on the same or opposite jaws. A control handle provided on the proximal end of the elongated shaft includes controls for opening and closing the jaws, and may include an actuator for sending current through the first and second heating elements. The first and second heating elements may be electrically connected in series, and the first heating element may be bifurcated such that it conducts about one half of the current as the second heating element. A force-limiting mechanism provided either within the control handle, in the elongated shaft, or at the jaws limits the pressure applied to the tissue by the jaws to ensure that the tissue is severed and the ends effectively welded within a short amount of time.
摘要翻译：用于切断和焊接组织，特别是血管的手术设备和方法。该装置包括细长轴，其在其远端具有一对相对可动的钳口。其中一个钳口上的第一加热元件适于加热至第一温度并在组织内形成焊接区域，而其中一个钳口上的第二加热元件适于加热至第二温度并切断组织在焊接区域内。第一和第二加热元件可以设置在相同或相对的夹爪上。设置在细长轴的近端的控制手柄包括用于打开和关闭钳口的控制器，并且可以包括用于通过第一和第二加热元件发送电流的致动器。第一和第二加热元件可以串联电连接，并且第一加热元件可以分叉，使得其作为第二加热元件传导大约电流的一半。设置在控制手柄，细长轴或钳口内的力限制机构限制由钳口施加到组织上的压力，以确保组织被切断并且端部在短时间内有效地焊接。

26. 发明授权

US08118864B1 Drug delivery endovascular graft 失效
标题翻译：药物输送血管内移植物
公开(公告)号：US08118864B1
公开(公告)日：2012-02-21
申请号：US10854014
申请日：2004-05-25
申请人： Arnold M. Escano , Joanne L. Parker , Rodney Reinhardt
发明人： Arnold M. Escano , Joanne L. Parker , Rodney Reinhardt
IPC分类号： A61F2/82
CPC分类号： A61F2/07 , A61F2/848 , A61F2/89 , A61F2002/065 , A61F2002/075 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054 , A61F2250/0067
摘要： An endovascular graft of the present invention embodies a graft system utilizing the textile fabric of the prosthesis for drug storage and delivery. These drug-eluting devices involve treating the textile fabric with therapeutic agents to provide a method of delivery to both the outer surface of the graft and the inner surface of the graft. An endovascular graft system having a fuzz texturing on the outer periphery of the graft where the texturing includes a therapeutic agent coating applied to the texturing material is also contemplated. An expandable attachment frame further includes drug storage and delivery capabilities in the cavities formed in the V-hooks and apices. Therapeutic agents can also included in the radiopaque coating or loading to serve as a reservoir for controlled drug delivery.
摘要翻译：本发明的血管内移植物体现了利用假体的纺织织物进行药物储存和递送的移植系统。这些药物洗脱装置包括用治疗剂处理纺织织物以提供递送到移植物的外表面和移植物的内表面的方法。还考虑了在移植物的外周上具有绒毛纹理的血管内移植物系统，其中纹理包括施加到纹理材料的治疗剂涂层。可扩展的附接框架还包括在V形钩和顶点中形成的空腔中的药物储存和递送能力。治疗剂也可以包括在不透射线的涂层或装载中以用作用于受控药物递送的储库。

27. 发明授权

US07666221B2 Lock modular graft component junctions 失效
标题翻译：锁定模块化移植物组件接头
公开(公告)号：US07666221B2
公开(公告)日：2010-02-23
申请号：US10222728
申请日：2002-08-16
申请人： Arnold M. Escano
发明人： Arnold M. Escano
IPC分类号： A61F2/06 , A61M29/00
CPC分类号： A61F2/07 , A61F2/848 , A61F2/89 , A61F2002/067 , A61F2002/075 , A61F2002/30322 , A61F2002/8483 , A61F2220/0008 , A61F2220/0016 , A61F2220/0041 , A61F2220/0075 , A61F2230/0067 , A61F2250/0026
摘要： The present invention embodies an endovascular graft having an attachment frame connection mechanism that allows placement of the main body component in vasculature in combination with limb components. Various limb component-to-main body component attachment mechanisms are provided which ensure a reliable bond while facilitating a smaller delivery profile.
摘要翻译：本发明体现了具有附接框架连接机构的血管内移植物，其允许主体部件与肢体部件组合在脉管系统中。提供了各种肢体部件到主体部件附接机构，其确保了可靠的粘合，同时有助于较小的传送轮廓。

28. 发明授权

US07591843B1 Delivery system for modular endograft with superior attachment system 失效
标题翻译：具有优良附件系统的模块化移植物输送系统
公开(公告)号：US07591843B1
公开(公告)日：2009-09-22
申请号：US10650477
申请日：2003-08-28
申请人： Arnold M. Escano , Patrick J. Massetti , Shuji Uemura , Michael F. Wei
发明人： Arnold M. Escano , Patrick J. Massetti , Shuji Uemura , Michael F. Wei
IPC分类号： A61F2/06 , A61F11/00
CPC分类号： A61F2/07 , A61F2/848 , A61F2/89 , A61F2002/067 , A61F2002/075 , A61F2002/30322 , A61F2002/8483 , A61F2220/0008 , A61F2220/0016 , A61F2220/0041 , A61F2220/0075 , A61F2230/0067 , A61F2250/0026
摘要： The present invention embodies delivery systems and methods of repairing vasculature. Various embodiments of bifurcated grafts and limb components can be delivered by delivery systems that provide enhanced control of self-expanding structure of a modular grafting system.
摘要翻译：本发明体现了输送系统和修复脉管系统的方法。分叉移植物和肢体组分的各种实施方案可以通过递送系统递送，其提供增强的对模块化接枝系统的自扩张结构的控制。

29. 发明授权

US07527645B2 Delivery system for endoluminal implant 失效
标题翻译：腔内植入物的输送系统
公开(公告)号：US07527645B2
公开(公告)日：2009-05-05
申请号：US11262145
申请日：2005-10-28
申请人： Juan I. Perez , Shuji Uemura , Arnold M. Escano , Mark Lemere , Richard Newhauser
发明人： Juan I. Perez , Shuji Uemura , Arnold M. Escano , Mark Lemere , Richard Newhauser
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/848 , A61F2/89 , A61F2/954 , A61F2002/067 , A61F2002/9511 , A61F2002/9665 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054
摘要： Delivery systems and methods for delivering modular endovascular graft devices that allow one portion of the repair device to be deployed while maintaining control of the other portions. One system includes an elongate inner member including an anchor stop ring, the anchor stop ring including a plurality of recesses, each sized to receive a portion of the trunk portion and embedding portion of a respective hook in the delivery configuration, each embedding portion extending radially outwardly at an acute angle relative to the trunk portion in the delivery configuration. The delivery systems are simpler to use, easier to manufacture and facilitate better packing of the repair device.
摘要翻译：用于递送模块化血管内移植装置的输送系统和方法，其允许修复装置的一部分被部署，同时保持对其它部分的控制。一个系统包括细长的内部构件，其包括锚定止动环，所述锚定止动环包括多个凹部，每个凹槽的尺寸设置成容纳相应钩子的主体部分和嵌入部分在输送构型中的一部分，每个嵌入部分径向延伸在输送构型中相对于躯干部分以锐角向外。输送系统使用起来更简单，更容易制造并促进修复装置的更好的包装。

30. 发明申请

US20090105805A1 ENDOVASCULAR GRAFT FOR PROVIDING A SEAL WITH VASCULATURE 失效
标题翻译：用于提供密封的血管内皮细胞
公开(公告)号：US20090105805A1
公开(公告)日：2009-04-23
申请号：US12339166
申请日：2008-12-19
申请人： Steven G. Baker , Tamara L. Trayer , Arnold M. Escano , Mark LeMere , Elizabeth A. McDermott
发明人： Steven G. Baker , Tamara L. Trayer , Arnold M. Escano , Mark LeMere , Elizabeth A. McDermott
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61B17/12022 , A61B17/12118 , A61B17/12136 , A61B17/1219 , A61B2017/1205 , A61F2/848 , A61F2/89 , A61F2002/075 , A61F2002/077 , A61F2230/0067 , A61F2250/0003 , D03D3/02 , D03D3/08 , D03D27/00 , Y10S623/921
摘要： A graft provided with a flexible sealing member to substantially prevent blood from leaking between the graft a lumen into which the graft is placed. In one embodiment, the flexible sealing member may be pressed against the vascular wall by an outwardly biased spring means attached to the sealing member. In other embodiments, the sealing member may be self-positioning upon deployment of the graft. The sealing member also may be formed into the shape of a toroid, which may be filled with thrombogenic material causing blood permeating into the toroid-shaped space to coagulate therein and hold the sealing member in place. It is also contemplated that the sealing member be formed from tufts of frayed yarn protruding circumferentially from the outer surface of the graft. A method of manufacturing such tufted yarn sealing members is also disclosed.
摘要翻译：移植物设置有柔性密封构件，以基本上防止血液在移植物之间泄漏，移植物被置于其中。在一个实施例中，柔性密封构件可以通过附接到密封构件的向外偏置的弹簧装置压靠在血管壁上。在其它实施例中，密封构件可以在移植物展开时自我定位。密封构件也可以形成为环形的形状，其可以填充血栓形成材料，导致血液渗透到环形空间中以凝结在其中并将密封构件保持在适当位置。还可以设想，密封构件由从移植物的外表面周向突出的磨粒纱线形成。还公开了这种簇绒纱线密封件的制造方法。

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