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    • 22. 发明授权
    • Therapy of estrogen-associated disorders
    • 雌激素相关疾病的治疗
    • US06599536B1
    • 2003-07-29
    • US09647092
    • 2000-12-05
    • Graham Edmund KellyAlan James Husband
    • Graham Edmund KellyAlan James Husband
    • A61K3578
    • A61K31/35A61K36/48A61K2300/00
    • A method for the treatment, prophylaxis, amelioration or prevention of disorders associated with abnormally high activity of steroidal estrogens, which includes administering to a human subject a composition comprising an isoflavone-containing extract of clover or chick peas, said extract comprising primarily biochanin, or a ratio of biochanin to one or more of the isoflavones from the group formononetin, daidzein and genistein in the range of from about 2:1 to about 5:1, optionally in association with one or more pharmaceutically acceptable carriers, excipients, auxiliaries and/or diluents is described. Also described are compositions and uses comprising the isoflavone containing extracts.
    • 一种用于治疗,预防,改善或预防与异常高活性的甾族雌激素相关的疾病的方法,其包括向人类受试者施用包含含有异黄酮的三叶草或鹰嘴豆提取物的组合物,所述提取物主要包含生长激素或 花呢素与一种或多种异黄酮组合的比例,其范围为约2:1至约5:1,任选与一种或多种药学上可接受的载体,赋形剂,助剂和/ 或稀释剂。 还描述了包含含异黄酮的提取物的组合物和用途。