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21. 发明授权

US4511017A Elevator system 失效
标题翻译：电梯系统
公开(公告)号：US4511017A
公开(公告)日：1985-04-16
申请号：US534005
申请日：1983-09-20
申请人： Robert C. MacDonald
发明人： Robert C. MacDonald
IPC分类号： B66B1/18 , B66B5/02
CPC分类号： B66B5/02
摘要： An elevator system, and method of operating same, in which emergency back-up service is provided all floors of a building when normal service is degraded, such as due to a dispatcher malfunction, a communication failure between the elevator cars of a bank of cars and a group supervisory controller or dispatcher, failure of the hall call circuits, and the like. When the emergency service is provided, a different initial block of floors is assigned to each elevator car, and as each elevator car completes a round trip its block of assignments are revised in a rotational manner. Thus, all floors are guaranteed service as long as at least one elevator car is operational.
摘要翻译：一种电梯系统及其操作方法，其中当正常服务劣化时，建筑物的所有楼层都提供紧急备用服务，例如由于调度员故障，一排汽车的电梯轿厢之间的通信故障以及组管理控制器或调度员，门厅呼叫电路的故障等。当提供紧急服务时，向每个电梯轿厢分配不同的初始楼层，并且当每个电梯轿厢完成往返时，其轮转方式被修改。因此，只要至少一台电梯轿厢正在运行，所有楼层都能得到保证。

22. 发明授权

US07732420B2 Combinations of transfection lipids exhibiting increased transfection efficiencies 有权
标题翻译：具有提高转染效率的转染脂质的组合
公开(公告)号：US07732420B2
公开(公告)日：2010-06-08
申请号：US10957977
申请日：2004-10-04
申请人： Robert C. MacDonald , Li Wang
发明人： Robert C. MacDonald , Li Wang
IPC分类号： A01N43/04 , A61K31/70 , C12N5/00 , C12N5/02 , G01N33/92
CPC分类号： C12N15/88
摘要： The present invention provides optimized transfection reagents comprising mixtures of cationiclipoids. In particular, the present invention provides DNA delivery vehicles based on identifying the optimal hydrophobicity of novel cationic phospholipid derivatives that, alone or in combination, form complexes with DNA (lipoplexes) and exhibit enhanced transfection activity.
摘要翻译：本发明提供包含阳离子脂质混合物的优化的转染试剂。特别地，本发明提供了基于鉴定与DNA单独或组合形成复合物（lipoplexes）并显示增强的转染活性的新型阳离子磷脂衍生物的最佳疏水性的DNA递送载体。

23. 发明授权

US5891714A Cationic phospholipids for transfection 失效
标题翻译：用于转染的阳离子磷脂
公开(公告)号：US5891714A
公开(公告)日：1999-04-06
申请号：US470923
申请日：1995-06-06
申请人： Gary W. Ashley , Robert C. MacDonald , Miho Shida
发明人： Gary W. Ashley , Robert C. MacDonald , Miho Shida
IPC分类号： C12P9/00 , A61K9/127 , C07F9/09 , C07F9/10 , C07F9/113 , C07F9/653 , C12N15/88 , C12N15/63
CPC分类号： C12N15/88 , A61K9/1272 , B82Y5/00 , C07F9/10 , C07F9/113 , C07F9/65324
摘要： Cationic phospholipids and their use in treating pathogen-associated disease are disclosed. The class of phospholipids comprises the phosphotriester derivatives of phosphoglycerides and sphingolipids. Liposomes comprising one or more of the cationic phospholipids are effective in the lipofection of nuclidic acids and are therefore useful in methods of treating disease.
摘要翻译：公开了阳离子磷脂及其在治疗病原体相关疾病中的用途。磷脂类包括磷酸甘油酯和鞘脂的磷酸三酯衍生物。包含一种或多种阳离子磷脂的脂质体在核苷酸的脂质转染中是有效的，因此可用于治疗疾病的方法。

24. 发明授权

US4782921A Coincident call optimization in an elevator dispatching system 失效
标题翻译：电梯调度系统中的重合调用优化
公开(公告)号：US4782921A
公开(公告)日：1988-11-08
申请号：US168791
申请日：1988-03-16
申请人： Robert C. MacDonald , Elsa Abrego
发明人： Robert C. MacDonald , Elsa Abrego
IPC分类号： B66B1/18 , B66B1/20 , B66B1/24
CPC分类号： B66B1/2458 , B66B2201/102 , B66B2201/211 , B66B2201/233
摘要： A method of optimizing the handling of coincident calls in an elevator system which employs ETA strategy in assigning hall calls to a plurality of elevator cars. The method dynamically biases the ETA value of a car having a car call for the floor of the hall call being assigned, with the bias being applied to favor assignment of the hall call to the car having the coincident car call. The amount of the bias is inversely proportional to the car travel distance between the advanced position (AVP floor) of the elevator car and the floor associated with the hall call (scan floor). The relative effect of the bias is predetermined for each floor by preselection of a constant K used in the bias calculation.
摘要翻译：一种在电梯系统中优化一致呼叫的处理方法，该电梯系统采用ETA策略来向多个电梯轿厢分配门厅呼叫。该方法动态地偏置具有被分配的门厅呼叫的楼层的轿厢呼梯的汽车的ETA值，并且施加偏压以有利于将门厅呼叫分配给具有重合汽车呼叫的汽车。偏置量与电梯轿厢的高级位置（AVP楼层）与门厅呼叫（扫描楼层）相关联的楼层之间的轿厢行驶距离成反比。通过预先选择偏差计算中使用的常数K，预定每个层的偏置的相对影响。

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