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21. 发明授权

US09575186B2 Multi-segment reconstruction 有权
标题翻译：多段重建
公开(公告)号：US09575186B2
公开(公告)日：2017-02-21
申请号：US12812040
申请日：2009-01-07
申请人： Xiyun Song , Zuo Zhao , Jinghan Ye , Lingxiong Shao
发明人： Xiyun Song , Zuo Zhao , Jinghan Ye , Lingxiong Shao
IPC分类号： G01T1/164 , A61B6/03 , A61B6/00 , G06T11/00
CPC分类号： G01T1/1642 , A61B6/037 , A61B6/5241 , G06T11/005
摘要： A medical imaging system includes a view transformation component (210) and a segment combiner (212). The transformation component (210) transforms projection data in each view of a plurality of individual segments, which each includes at least one view. The transformed projection data for substantially similar views across the plurality of individual segments have a common radius of rotation. The segment combiner (212) combines the transformed projection data to produce a single data set that includes the transformed projection data for each of the views of each of the plurality of individual segments.
摘要翻译：医疗成像系统包括视角变换组件（210）和段组合器（212）。转换组件（210）在多个单独的段的每个视图中转换投影数据，每个段各自包括至少一个视图。用于跨越多个单独段的基本类似视图的变换的投影数据具有公共的旋转半径。段组合器（212）组合变换的投影数据以产生单个数据集，其包括用于多个单独段中的每一个的每个视图的变换的投影数据。

22. 发明授权

US09025846B2 Sparse data reconstruction for gated X-ray CT imaging 有权
标题翻译：门控X线CT成像的稀疏数据重建
公开(公告)号：US09025846B2
公开(公告)日：2015-05-05
申请号：US13576823
申请日：2011-01-12
申请人： Hongjie Liang , Jinghan Ye , Jiong Wang , Lingxiong Shao
发明人： Hongjie Liang , Jinghan Ye , Jiong Wang , Lingxiong Shao
IPC分类号： G06K9/00 , G06T7/00 , G06T11/00
CPC分类号： G06T7/0012 , G06T11/006 , G06T2211/412
摘要： When imaging a compact structure, such as a calcium deposit in a patient's heart, a slow scan (e.g., less than approximately 6 rpm) CT data acquisition is performed, wherein data is continuously but sparsely acquired during around a 360° revolution around the patient. Arc segments are defined that equate to one heart cycle (e.g., heartbeat) given the patient's heart rate and the speed of the CT gantry. Electrocardiogram signal data is used to identify sets of acquired projection data that correspond to each of a plurality of heart cycle phases during which the heart is relatively still. A sparse reconstruction algorithm is executed on the identified sets of sparse projection data to generate images for each heart cycle phase from the scan data acquired for that phase across all heart cycles.
摘要翻译：当对紧密结构（例如患者心脏中的钙沉积物）进行成像时，执行慢扫描（例如，小于约6rpm）CT数据采集，其中数据在围绕患者的360度旋转周围连续但稀疏地获取。定义弧段，其等同于给定患者的心率和CT台架的速度的一个心脏周期（例如，心跳）。心电图信号数据用于识别与心脏相对静止的多个心脏周期阶段中的每一个相对应的获取的投影数据集。对所识别的稀疏投影数据集执行稀疏重建算法，以从针对所述心脏周期的该阶段获取的扫描数据生成每个心脏周期相位的图像。

23. 发明申请

US20130142411A1 DUAL MODALITY IMAGING INCLUDING QUALITY METRICS 有权
标题翻译：双重模态成像，包括质量度量
公开(公告)号：US20130142411A1
公开(公告)日：2013-06-06
申请号：US13817150
申请日：2011-08-17
申请人： Angela Da Silva , Horace Hines , Lingxiong Shao , Hongjie Liang , Anna Exner , Andreas Goedicke
发明人： Angela Da Silva , Horace Hines , Lingxiong Shao , Hongjie Liang , Anna Exner , Andreas Goedicke
IPC分类号： G06T11/00
CPC分类号： G06T11/003 , G06T7/33 , G06T11/008 , G06T2207/10084 , G06T2207/30048
摘要： An anatomical image data set and an emission image data set are acquired for a subject. An attenuation map is generated from the anatomical image data set. The emission image data set is reconstructed to generate an emission image. The reconstructing includes correcting for attenuation of emission radiation in the subject using the attenuation map. A value is calculated for a quality assurance (QA) metric quantifying alignment of the attenuation map with the emission image. The emission image is displayed or printed together with the calculated quality assurance metric. In some embodiments, prior to the reconstructing the attenuation map is registered with the emission image data set by performing a global rigid registration followed by a local non-rigid registration of a region of interest.
摘要翻译：获取对象的解剖图像数据集和发射图像数据集。从解剖图像数据集生成衰减图。重建发射图像数据集以产生发射图像。重建包括使用衰减图校正受试者中发射辐射的衰减。针对质量保证（QA）量度计算衰减图与发射图像的对准的值。排放图像与计算的质量保证度量一起显示或打印。在一些实施例中，在重建之前，通过执行全局刚性配准，随后是感兴趣区域的局部非刚性配准，将衰减图与发射图像数据集进行配准。

24. 发明申请

US20130070994A1 SPARSE DATA RECONSTRUCTION FOR GATED X-RAY CT IMAGING 有权
标题翻译：用于定位X射线CT成像的稀疏数据重建
公开(公告)号：US20130070994A1
公开(公告)日：2013-03-21
申请号：US13576823
申请日：2011-01-12
申请人： Hongjie Liang , Jinghan Ye , Jiong Wang , Lingxiong Shao
发明人： Hongjie Liang , Jinghan Ye , Jiong Wang , Lingxiong Shao
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , G06T11/006 , G06T2211/412
摘要： When imaging a compact structure, such as a calcium deposit in a patient's heart, a slow scan (e.g., less than approximately 6 rpm) CT data acquisition is performed, wherein data is continuously but sparsely acquired during around a 360° revolution around the patient. Arc segments are defined that equate to one heart cycle (e.g., heartbeat) given the patient's heart rate and the speed of the CT gantry. Electrocardiogram signal data is used to identify sets of acquired projection data that correspond to each of a plurality of heart cycle phases during which the heart is relatively still. A sparse reconstruction algorithm is executed on the identified sets of sparse projection data to generate images for each heart cycle phase from the scan data acquired for that phase across all heart cycles.
摘要翻译：当对紧密结构（例如患者心脏中的钙沉积物）进行成像时，执行慢扫描（例如，小于约6rpm）CT数据采集，其中数据在围绕患者的360度旋转周围连续但稀疏地获取。定义弧段，其等同于给定患者的心率和CT台架的速度的一个心脏周期（例如，心跳）。心电图信号数据用于识别与心脏相对静止的多个心脏周期阶段中的每一个相对应的获取的投影数据集。对所识别的稀疏投影数据集执行稀疏重建算法，以从针对所述心脏周期的该阶段获取的扫描数据生成每个心脏周期相位的图像。

25. 发明申请

US20090202125A1 RESTORATION OF THE NUCLEAR MEDICINE 2D PLANAR IMAGE BY ITERATIVE CONSTRAINED DECONVOLUTION 有权
标题翻译：通过迭代约束解卷积恢复核医学2D平面图像
公开(公告)号：US20090202125A1
公开(公告)日：2009-08-13
申请号：US11719420
申请日：2005-11-04
申请人： Zuo Zhao , Lingxiong Shao , Jinghan Ye
发明人： Zuo Zhao , Lingxiong Shao , Jinghan Ye
IPC分类号： G06K9/00 , G06T5/00 , G01T1/29
CPC分类号： G06T5/003 , G06T2207/10072 , G06T2207/30004
摘要： A medical imaging system (10) includes at least one radiation detection head (16) disposed adjacent a subject receiving aperture (18) to detect radiation from a subject. The detected radiation is reconstructed into at least one initial 2D projection image (μ). Resolution in each initial 2D image (μ) is restored by using the extended iterative constrained deconvolution algorithm by incorporating different estimates of the system response function which estimates correspond to different distances between the detection head and the origins of the detected radiation. Measured response functions are used to restore a series of images. The optimal image is determined by automatic searching with the figure of merit, by user's observation, or by using blind deconvolution for a concurrent estimating of the system response function and updating the original image.
摘要翻译：医疗成像系统（10）包括邻近被检体接收孔（18）设置的至少一个放射线检测头（16），以检测来自受试者的辐射。将检测到的辐射重建为至少一个初始2D投影图像（μ）。通过使用扩展迭代约束去卷积算法，通过并入系统响应函数的不同估计值来恢复每个初始2D图像（mu）中的分辨率，该估计对应于检测头与检测到的辐射源之间的不同距离。测量的响应功能用于恢复一系列图像。通过用户的观察自动搜索，通过使用盲解卷积来同时估计系统响应函数和更新原始图像来确定最佳图像。

26. 发明申请

US20090087065A1 ACCOUNTING FOR FOREIGN OBJECTS WHEN CREATING CT-BASED ATTENUATION MAPS 审中-公开
标题翻译：在创建基于CT的衰减准则时对外部对象的会计
公开(公告)号：US20090087065A1
公开(公告)日：2009-04-02
申请号：US12278001
申请日：2007-01-29
申请人： Angela J. DaSilva , Lingxiong Shao
发明人： Angela J. DaSilva , Lingxiong Shao
IPC分类号： G06K9/00
CPC分类号： G01T1/1615 , A61B6/037 , A61B6/4452 , A61B6/4458
摘要： In a method for generating an attenuation map (30), image elements of a reconstructed tomographic image (24) are segmented into at least first, second, and third classes (50, 52, 54). Each image element of the first class (50) is transformed using a first image element value-dependent attenuation transform (60). Each image element of the second class (52) is transformed using a second image element value-dependent attenuation transform (62) different from the first image element value-dependent attenuation transform. Each image element of the third class (54) is transformed using a third image element value-dependent attenuation transform (64) different from both the first and second image element value-dependent attenuation transforms.
摘要翻译：在用于产生衰减图（30）的方法中，重构断层图像（24）的图像元素被分割为至少第一，第二和第三类（50,52,54）。使用第一图像元素值依赖衰减变换（60）来变换第一类（50）的每个图像元素。使用与第一图像元素值相关的衰减变换不同的第二图像元素值依赖衰减变换（62）来变换第二类（52）的每个图像元素。使用与第一和第二图像元素值相关的衰减变换两者不同的第三图像元素值依赖衰减变换（64）来变换第三类（54）的每个图像元素。

27. 发明授权

US06410920B1 Method and apparatus for performing correction of emission contamination and deadtime loss in a medical imaging system 失效
标题翻译：用于执行医疗成像系统中的排放污染和死时间损失校正的方法和装置
公开(公告)号：US06410920B1
公开(公告)日：2002-06-25
申请号：US09400745
申请日：1999-09-21
申请人： Lingxiong Shao , Hugo Bertelsen , Peter Nelleman , Horace Hines
发明人： Lingxiong Shao , Hugo Bertelsen , Peter Nelleman , Horace Hines
IPC分类号： G01T1164
CPC分类号： G01T1/2985 , A61B6/00 , A61B6/037 , G01T1/1611 , G01T1/171
摘要： A method of correcting for deadtime and for emission contamination of a transmission scan in a nuclear camera system is provided. The transmission scan is used to correct positron emission tomography (PET) images for attenuation. The camera system includes two detectors and two corresponding single-photon point sources that are collimated to produce fanbeam illumination profiles. A transmission detection window and an emission contamination detection window is defined on each detector. Radiation from each source is scanned axially across the field of view of the corresponding detector in synchronization with the corresponding transmission detection window to acquire transmission projection data. The emission contamination detection windows are also scanned axially concurrently with, but offset from, the transmission detection windows to acquire emission data. Events detected in the transmission detection windows are used to add counts from appropriate locations of the transmission projection on an event-by-event basis in real-time. Events detected in the emission contamination detection windows are used to subtract counts from appropriate locations of the transmission projection on an event-by-event basis as those events are detected. The number of counts by which a given location is incremented or decremented for each detected event is determined event-by-event from a look-up table based on the current singles rate.
摘要翻译：提供了一种校正核相机系统中的发射扫描的死区时间和发射污染的方法。透射扫描用于校正正电子发射断层摄影（PET）图像以进行衰减。相机系统包括两个检测器和两个对准的单光子点源，其被准直以产生扇形照明轮廓。在每个检测器上定义传输检测窗口和排放污染检测窗口。与对应的传输检测窗口同步地从相应检测器的视野轴向扫描来自每个源的辐射以获取传输投影数据。排放污染检测窗口也与传输检测窗口轴向同时扫描但偏移以获取发射数据。在传输检测窗口中检测到的事件用于实时地逐个事件地从传输投影的适当位置添加计数。在发射污染检测窗口中检测到的事件用于在检测到事件时逐个事件基础上从传输投影的适当位置减去计数。基于当前单打率，从查找表中逐个事件确定给定位置对于每个检测到的事件递增或递减的计数次数。

28. 发明授权

US06259097B1 Use of transmission pre-scan of an object to be imaged to determine duration of transmission scan 失效
标题翻译：使用要成像对象的传输预扫描来确定传输扫描的持续时间
公开(公告)号：US06259097B1
公开(公告)日：2001-07-10
申请号：US09322295
申请日：1999-05-28
申请人： Lingxiong Shao , Jinghan Ye , Soo Kuen Hom
发明人： Lingxiong Shao , Jinghan Ye , Soo Kuen Hom
IPC分类号： G01T120
CPC分类号： G01T1/1644 , A61B6/037 , A61B6/4258
摘要： A transmission pre-scan of a patient is used in a nuclear medicine imaging system to determine the duration of a subsequent transmission scan of the patient. The transmission scan is for acquiring an attenuation map of the patient to correct emission data of the patient for non-uniform attenuation. As a result, the patient's exposure to radiation during the transmission scan is not excessive, yet transmission image quality is maintained. A radiation transmission source and a radiation detector are operated to perform the transmission pre-scan of the object, during which the transmission source remains in a fixed position. Downscatter correction is applied to correct the transmission pre-scan data for emission contamination. Count values from the pre-scan data are integrated axially. A water-equivalent cross-section value of the patient is then determined based on data acquired from the transmission pre-scan, and the duration of the transmission scan is computed based on the water-equivalent cross-section value.
摘要翻译：在核医学成像系统中使用患者的透射预扫描来确定患者的后续透射扫描的持续时间。透射扫描用于获取患者的衰减图，以校正患者的不均匀衰减的发射数据。结果，患者在透射扫描期间的辐射暴露并不过分，而是保持透射图像质量。操作辐射透射源和辐射检测器以执行物体的透射预扫描，在此期间透射源保持在固定位置。应用向下散射校正来校正发射预扫描数据以发射污染。来自预扫描数据的计数值被轴向积分。然后，基于从发送预扫描获取的数据来确定患者的水当量横截面值，并且基于水当量横截面值计算发送扫描的持续时间。

29. 发明授权

US5999588A Deadtime correction in a nuclear medicine imaging system 失效
标题翻译：核医学成像系统中的死时校正
公开(公告)号：US5999588A
公开(公告)日：1999-12-07
申请号：US62222
申请日：1998-04-17
申请人： Lingxiong Shao , Peter Nellemann , David Coles , Hugo Bertelsen , Jacobus Koster
发明人： Lingxiong Shao , Peter Nellemann , David Coles , Hugo Bertelsen , Jacobus Koster
IPC分类号： G01T1/164 , G01T20060101 , G01T1/161 , G01T1/20 , G06T5/00
CPC分类号： G01T1/1647 , G01T1/171
摘要： A method of correcting for deadtime in an attenuation map generated by a nuclear medicine imaging system is provided. The imaging system includes a gamma ray detector that is rotatable about an object to be imaged. A region is defined on the imaging surface of the detector, such as the edge of the field of view of the detector, such that during a transmission scan of the object, the radiation shadow of the object is substantially less likely to fall upon the defined region than upon other regions of the imaging surface. A blank transmission scan is then performed, including recording the radiation intensity level detected in the region as a reference intensity level. A transmission scan of the object is then performed to acquire an attenuation map of the object, including recording a radiation intensity level detected in the first region during the transmission scan. A correction value is then determined as the ratio of the reference intensity level to the intensity level detected in the region during the transmission scan. The attenuation map is then corrected for deadtime based on the correction value.
摘要翻译：提供了一种校正由核医学成像系统生成的衰减图中的死时间的方法。成像系统包括可围绕待成像对象旋转的伽马射线检测器。区域被定义在检测器的成像表面上，例如检测器视场的边缘，使得在物体的透射扫描期间，物体的辐射阴影实际上不太可能落在所定义的区域比成像表面的其他区域。然后执行空白传输扫描，包括将在该区域中检测到的辐射强度水平记录为参考强度水平。然后执行对象的传输扫描以获取对象的衰减图，包括记录在传输扫描期间在第一区域中检测到的辐射强度级别。然后将校正值确定为在透射扫描期间在该区域中检测到的基准亮度水平与强度水平的比率。然后根据校正值对衰减图进行死区校正。

30. 发明授权

US10043297B2 Method and system for managing imaging data 有权
公开(公告)号：US10043297B2
公开(公告)日：2018-08-07
申请号：US13991264
申请日：2011-11-25
申请人： Lingxiong Shao
发明人： Lingxiong Shao
IPC分类号： G06T11/60 , G06F19/00
摘要： A method and system for managing imaging data are provided. In one aspect, imaging data is stored in combination with user-generated information relating to the imaging data. In various other aspects, an image file header structure including user-generated information, a software editing tool to record user-generated information, and an imaging display tool to correlate imaging data and user-generated information are provided.

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