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1. 发明授权

US06259097B1 Use of transmission pre-scan of an object to be imaged to determine duration of transmission scan 失效
标题翻译：使用要成像对象的传输预扫描来确定传输扫描的持续时间
公开(公告)号：US06259097B1
公开(公告)日：2001-07-10
申请号：US09322295
申请日：1999-05-28
申请人： Lingxiong Shao , Jinghan Ye , Soo Kuen Hom
发明人： Lingxiong Shao , Jinghan Ye , Soo Kuen Hom
IPC分类号： G01T120
CPC分类号： G01T1/1644 , A61B6/037 , A61B6/4258
摘要： A transmission pre-scan of a patient is used in a nuclear medicine imaging system to determine the duration of a subsequent transmission scan of the patient. The transmission scan is for acquiring an attenuation map of the patient to correct emission data of the patient for non-uniform attenuation. As a result, the patient's exposure to radiation during the transmission scan is not excessive, yet transmission image quality is maintained. A radiation transmission source and a radiation detector are operated to perform the transmission pre-scan of the object, during which the transmission source remains in a fixed position. Downscatter correction is applied to correct the transmission pre-scan data for emission contamination. Count values from the pre-scan data are integrated axially. A water-equivalent cross-section value of the patient is then determined based on data acquired from the transmission pre-scan, and the duration of the transmission scan is computed based on the water-equivalent cross-section value.
摘要翻译：在核医学成像系统中使用患者的透射预扫描来确定患者的后续透射扫描的持续时间。透射扫描用于获取患者的衰减图，以校正患者的不均匀衰减的发射数据。结果，患者在透射扫描期间的辐射暴露并不过分，而是保持透射图像质量。操作辐射透射源和辐射检测器以执行物体的透射预扫描，在此期间透射源保持在固定位置。应用向下散射校正来校正发射预扫描数据以发射污染。来自预扫描数据的计数值被轴向积分。然后，基于从发送预扫描获取的数据来确定患者的水当量横截面值，并且基于水当量横截面值计算发送扫描的持续时间。

2. 发明授权

US08208599B2 Iterative reconstruction with enhanced noise control filtering 有权
标题翻译：具有增强噪声控制滤波的迭代重建
公开(公告)号：US08208599B2
公开(公告)日：2012-06-26
申请号：US12067185
申请日：2006-08-21
申请人： Jinghan Ye , Lingxiong Shao , Zuo Zhao , Mary K. Durbin
发明人： Jinghan Ye , Lingxiong Shao , Zuo Zhao , Mary K. Durbin
IPC分类号： G06K9/00
CPC分类号： G01T1/2985 , A61B6/037 , G06T5/002 , G06T11/006 , G06T2207/10081 , G06T2207/10104 , G06T2207/10108 , G06T2207/30004 , G06T2211/424
摘要： An imaging system (10) comprises at least one radiation detector (20) disposed adjacent a subject receiving aperture (18) to detect radiation from a subject, receive the radiation and generate measured data. An image processor (38) iteratively reconstructs the detected radiation into image representations, in each reconstruction iteration the image processor (38) applies noise reduction algorithms to at least a difference between the measured data and a portion of a previous iteration image representation.
摘要翻译：成像系统（10）包括邻近对象接收孔（18）设置的至少一个辐射检测器（20），以检测来自对象的辐射，接收辐射并产生测量数据。图像处理器（38）将检测到的辐射重建成图像表示，在每个重建迭代中，图像处理器（38）将噪声降低算法应用于至少测量数据与先前迭代图像表示的一部分之间的差异。

3. 发明申请

US20100284598A1 IMAGE REGISTRATION ALIGNMENT METRIC 审中-公开
标题翻译：图像注册对齐度
公开(公告)号：US20100284598A1
公开(公告)日：2010-11-11
申请号：US12812045
申请日：2009-01-07
申请人： Zuo Zhao , Lingxiong Shao , Jinghan Ye , Xiyun Song
发明人： Zuo Zhao , Lingxiong Shao , Jinghan Ye , Xiyun Song
IPC分类号： G06K9/32 , G06K9/00
CPC分类号： G06T7/33 , G06T2207/10081 , G06T2207/10108 , G06T2207/30048
摘要： A method includes obtaining a combined data set that includes first and second imaging data sets. The first and second imaging data sets correspond to different imaging modalities. The method further includes determining a metric indicative of an alignment between the first and second imaging data sets in the combined data set. The method further includes presenting the metric in a human readable format.
摘要翻译：一种方法包括获得包括第一和第二成像数据集的组合数据集。第一和第二成像数据集对应于不同的成像模态。该方法还包括确定指示组合数据集中的第一和第二成像数据集之间的对准的度量。该方法还包括以人类可读格式呈现度量。

4. 发明申请

US20100278412A1 MULTI-SEGMENT RECONSTRUCTION 有权
标题翻译：多部门重建
公开(公告)号：US20100278412A1
公开(公告)日：2010-11-04
申请号：US12812040
申请日：2009-01-07
申请人： Xiyun Song , Zuo Zhao , Jinghan Ye , Lingxiong Shao
发明人： Xiyun Song , Zuo Zhao , Jinghan Ye , Lingxiong Shao
IPC分类号： G06T7/00
CPC分类号： G01T1/1642 , A61B6/037 , A61B6/5241 , G06T11/005
摘要： A medical imaging system includes a view transformation component (210) and a segment combiner (212). The transformation component (210) transforms projection data in each view of a plurality of individual segments, which each includes at least one view. The transformed projection data for substantially similar views across the plurality of individual segments have a common radius of rotation. The segment combiner (212) combines the transformed projection data to produce a single data set that includes the transformed projection data for each of the views of each of the plurality of individual segments.
摘要翻译：医疗成像系统包括视角变换组件（210）和段组合器（212）。转换组件（210）在多个单独的段的每个视图中转换投影数据，每个段各自包括至少一个视图。用于跨越多个单独段的基本类似视图的变换的投影数据具有公共的旋转半径。段组合器（212）组合变换的投影数据以产生单个数据集，其包括用于多个单独段中的每一个的每个视图的变换的投影数据。

5. 发明申请

US20070183642A1 ITERATIVE RECONSTRUCTION OF MULTIPLE-PEAK ISOTOPE IMAGES 有权
标题翻译：多峰同位素图像的迭代重建
公开(公告)号：US20070183642A1
公开(公告)日：2007-08-09
申请号：US11627087
申请日：2007-01-25
申请人： Jinghan Ye , Mary K. Durbin , Xiyun Song , Lingxiong Shao
发明人： Jinghan Ye , Mary K. Durbin , Xiyun Song , Lingxiong Shao
IPC分类号： G06K9/00
CPC分类号： G06T11/006 , G06T2211/408 , G06T2211/424
摘要： In an imaging method, estimated data is iteratively projected and backprojected. The iterative projecting and backprojecting includes projecting or backprojecting the estimated data along parallel paths each employing energy-dependent parameters appropriate for a different energy. During each iteration, the estimated data is adjusted based on comparison of the estimated data with measured data.
摘要翻译：在成像方法中，估计数据被迭代地投影并反向投影。迭代投影和反向投影包括沿着并行路径投影或反投影估计数据，每个并行路径采用适用于不同能量的能量相关参数。在每次迭代期间，基于估计数据与测量数据的比较来调整估计数据。

6. 发明授权

US09575186B2 Multi-segment reconstruction 有权
标题翻译：多段重建
公开(公告)号：US09575186B2
公开(公告)日：2017-02-21
申请号：US12812040
申请日：2009-01-07
申请人： Xiyun Song , Zuo Zhao , Jinghan Ye , Lingxiong Shao
发明人： Xiyun Song , Zuo Zhao , Jinghan Ye , Lingxiong Shao
IPC分类号： G01T1/164 , A61B6/03 , A61B6/00 , G06T11/00
CPC分类号： G01T1/1642 , A61B6/037 , A61B6/5241 , G06T11/005
摘要： A medical imaging system includes a view transformation component (210) and a segment combiner (212). The transformation component (210) transforms projection data in each view of a plurality of individual segments, which each includes at least one view. The transformed projection data for substantially similar views across the plurality of individual segments have a common radius of rotation. The segment combiner (212) combines the transformed projection data to produce a single data set that includes the transformed projection data for each of the views of each of the plurality of individual segments.
摘要翻译：医疗成像系统包括视角变换组件（210）和段组合器（212）。转换组件（210）在多个单独的段的每个视图中转换投影数据，每个段各自包括至少一个视图。用于跨越多个单独段的基本类似视图的变换的投影数据具有公共的旋转半径。段组合器（212）组合变换的投影数据以产生单个数据集，其包括用于多个单独段中的每一个的每个视图的变换的投影数据。

7. 发明授权

US09025846B2 Sparse data reconstruction for gated X-ray CT imaging 有权
标题翻译：门控X线CT成像的稀疏数据重建
公开(公告)号：US09025846B2
公开(公告)日：2015-05-05
申请号：US13576823
申请日：2011-01-12
申请人： Hongjie Liang , Jinghan Ye , Jiong Wang , Lingxiong Shao
发明人： Hongjie Liang , Jinghan Ye , Jiong Wang , Lingxiong Shao
IPC分类号： G06K9/00 , G06T7/00 , G06T11/00
CPC分类号： G06T7/0012 , G06T11/006 , G06T2211/412
摘要： When imaging a compact structure, such as a calcium deposit in a patient's heart, a slow scan (e.g., less than approximately 6 rpm) CT data acquisition is performed, wherein data is continuously but sparsely acquired during around a 360° revolution around the patient. Arc segments are defined that equate to one heart cycle (e.g., heartbeat) given the patient's heart rate and the speed of the CT gantry. Electrocardiogram signal data is used to identify sets of acquired projection data that correspond to each of a plurality of heart cycle phases during which the heart is relatively still. A sparse reconstruction algorithm is executed on the identified sets of sparse projection data to generate images for each heart cycle phase from the scan data acquired for that phase across all heart cycles.
摘要翻译：当对紧密结构（例如患者心脏中的钙沉积物）进行成像时，执行慢扫描（例如，小于约6rpm）CT数据采集，其中数据在围绕患者的360度旋转周围连续但稀疏地获取。定义弧段，其等同于给定患者的心率和CT台架的速度的一个心脏周期（例如，心跳）。心电图信号数据用于识别与心脏相对静止的多个心脏周期阶段中的每一个相对应的获取的投影数据集。对所识别的稀疏投影数据集执行稀疏重建算法，以从针对所述心脏周期的该阶段获取的扫描数据生成每个心脏周期相位的图像。

8. 发明申请

US20130070994A1 SPARSE DATA RECONSTRUCTION FOR GATED X-RAY CT IMAGING 有权
标题翻译：用于定位X射线CT成像的稀疏数据重建
公开(公告)号：US20130070994A1
公开(公告)日：2013-03-21
申请号：US13576823
申请日：2011-01-12
申请人： Hongjie Liang , Jinghan Ye , Jiong Wang , Lingxiong Shao
发明人： Hongjie Liang , Jinghan Ye , Jiong Wang , Lingxiong Shao
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , G06T11/006 , G06T2211/412
摘要： When imaging a compact structure, such as a calcium deposit in a patient's heart, a slow scan (e.g., less than approximately 6 rpm) CT data acquisition is performed, wherein data is continuously but sparsely acquired during around a 360° revolution around the patient. Arc segments are defined that equate to one heart cycle (e.g., heartbeat) given the patient's heart rate and the speed of the CT gantry. Electrocardiogram signal data is used to identify sets of acquired projection data that correspond to each of a plurality of heart cycle phases during which the heart is relatively still. A sparse reconstruction algorithm is executed on the identified sets of sparse projection data to generate images for each heart cycle phase from the scan data acquired for that phase across all heart cycles.
摘要翻译：当对紧密结构（例如患者心脏中的钙沉积物）进行成像时，执行慢扫描（例如，小于约6rpm）CT数据采集，其中数据在围绕患者的360度旋转周围连续但稀疏地获取。定义弧段，其等同于给定患者的心率和CT台架的速度的一个心脏周期（例如，心跳）。心电图信号数据用于识别与心脏相对静止的多个心脏周期阶段中的每一个相对应的获取的投影数据集。对所识别的稀疏投影数据集执行稀疏重建算法，以从针对所述心脏周期的该阶段获取的扫描数据生成每个心脏周期相位的图像。

9. 发明申请

US20090202125A1 RESTORATION OF THE NUCLEAR MEDICINE 2D PLANAR IMAGE BY ITERATIVE CONSTRAINED DECONVOLUTION 有权
标题翻译：通过迭代约束解卷积恢复核医学2D平面图像
公开(公告)号：US20090202125A1
公开(公告)日：2009-08-13
申请号：US11719420
申请日：2005-11-04
申请人： Zuo Zhao , Lingxiong Shao , Jinghan Ye
发明人： Zuo Zhao , Lingxiong Shao , Jinghan Ye
IPC分类号： G06K9/00 , G06T5/00 , G01T1/29
CPC分类号： G06T5/003 , G06T2207/10072 , G06T2207/30004
摘要： A medical imaging system (10) includes at least one radiation detection head (16) disposed adjacent a subject receiving aperture (18) to detect radiation from a subject. The detected radiation is reconstructed into at least one initial 2D projection image (μ). Resolution in each initial 2D image (μ) is restored by using the extended iterative constrained deconvolution algorithm by incorporating different estimates of the system response function which estimates correspond to different distances between the detection head and the origins of the detected radiation. Measured response functions are used to restore a series of images. The optimal image is determined by automatic searching with the figure of merit, by user's observation, or by using blind deconvolution for a concurrent estimating of the system response function and updating the original image.
摘要翻译：医疗成像系统（10）包括邻近被检体接收孔（18）设置的至少一个放射线检测头（16），以检测来自受试者的辐射。将检测到的辐射重建为至少一个初始2D投影图像（μ）。通过使用扩展迭代约束去卷积算法，通过并入系统响应函数的不同估计值来恢复每个初始2D图像（mu）中的分辨率，该估计对应于检测头与检测到的辐射源之间的不同距离。测量的响应功能用于恢复一系列图像。通过用户的观察自动搜索，通过使用盲解卷积来同时估计系统响应函数和更新原始图像来确定最佳图像。

10. 发明授权

US09420974B2 Method and apparatus for attenuation correction 有权
标题翻译：用于衰减校正的方法和装置
公开(公告)号：US09420974B2
公开(公告)日：2016-08-23
申请号：US12995679
申请日：2009-05-29
申请人： Jinghan Ye , Hongjie Liang , John Vesel , David Sowards-Emmerd , Lingxiong Shao , Jody L. Garrard
发明人： Jinghan Ye , Hongjie Liang , John Vesel , David Sowards-Emmerd , Lingxiong Shao , Jody L. Garrard
IPC分类号： G06K9/00 , A61B6/03 , A61B6/00 , G01T1/161
CPC分类号： A61B6/032 , A61B6/037 , A61B6/466 , A61B6/503 , A61B6/5235 , A61B6/541 , G01T1/1611
摘要： A method and apparatus of image reconstruction attenuation correction in PET or SPECT cardiac imaging is provided. A volumetric attenuation imaging scan by an X-ray source may be used to generate a gamma ray attenuation map. The volumetric attenuation imaging scan may be randomized, and may be performed while the imaged subject is breathing.
摘要翻译：提供PET或SPECT心脏成像中图像重建衰减校正的方法和装置。可以使用X射线源的体积衰减成像扫描来产生伽马射线衰减图。体积衰减成像扫描可以是随机化的，并且可以在成像对象呼吸时执行。

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