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21. 发明授权

US5993396A Method and apparatus for determining a minimum wait time between blood pressure determinations 失效
标题翻译：用于确定血压测定之间的最小等待时间的方法和装置
公开(公告)号：US5993396A
公开(公告)日：1999-11-30
申请号：US21869
申请日：1998-02-11
申请人： Bruce Friedman , Richard Avoy , Richard Medero
发明人： Bruce Friedman , Richard Avoy , Richard Medero
IPC分类号： A61B5/022 , A61N5/00
CPC分类号： A61B5/02225 , A61B5/022
摘要： An automated non-invasive blood pressure (NIBP) monitor having a stat mode of operation wherein several cycles of blood pressure measurement are undertaken in rapid succession by inflating a cuff on an appendage of the patient in order to quickly provide a clinician with readings of blood pressure and pulse rate. The NIBP monitor adaptively determines a minimum wait time between stat mode blood pressure measurement cycles by recognizing that the minimum wait time is proportional to the area under the pressure-time curve of the previous inflation/deflation measurement cycle. The calculated area is divided by a clinical constant derived from sampled patient data to determine the minimum wait time. The minimum wait time between blood measurement cycles so determined allows for venous return of blood that has accumulated in a patient's extremity and minimizes the discomfort experienced by the patient while maximizing the amount of collected data.
摘要翻译：一种具有统计操作模式的自动无创血压（NIBP）监测器，其中通过在患者的附属物上充气袖带来快速连续地进行几个周期的血压测量，以便快速向临床医生提供血液读数压力和脉率。 NIBP监视器通过识别最小等待时间与先前的充气/放气测量周期的压力 - 时间曲线下的面积成比例，自适应地确定在stat模式血压测量周期之间的最小等待时间。计算的面积除以从采样患者数据得出的临床常数，以确定最小等待时间。如此确定的血液测量循环之间的最小等待时间允许在患者的肢体中累积的血液的静脉回流并且最小化患者经历的不适，同时最大化收集的数据量。

22. 发明授权

US08137273B2 Systems and methods for integrating hemodynamic and imaging examinations 有权
标题翻译：整合血流动力学和影像学检查的系统和方法
公开(公告)号：US08137273B2
公开(公告)日：2012-03-20
申请号：US12362942
申请日：2009-01-30
申请人： Deborah Ann Everett , Bruce Friedman , Paul Lawrence Mullen , William Alphonsus Zang
发明人： Deborah Ann Everett , Bruce Friedman , Paul Lawrence Mullen , William Alphonsus Zang
IPC分类号： A61B8/00
CPC分类号： A61B5/022 , A61B5/02007 , A61B8/06
摘要： Hemodynamic data and imaging data are obtained about a patient, and the data is combined to generate a single report integrating same. While a hemodynamic system obtains the hemodynamic data, an imaging system obtains the imaging data. Preferably, the report confirms the absence or presence (and/or severity) of peripheral arterial disease, including quantitative data. The hemodynamic system and the imaging system can communicate directly, indirectly, and/or wirelessly. They may be contained within a common enclosure and/or integrated into a single apparatus. Either or both of the hemodynamic system and/or the imaging system can also be configured to measure the blood pressure of the patient. Preferably, the imaging system is an ultrasound imaging system, and improved workflows for diagnosing peripheral arterial disease result.
摘要翻译：获得关于患者的血流动力学数据和成像数据，并且将数据组合以产生整合相同的单个报告。当血液动力学系统获得血液动力学数据时，成像系统获得成像数据。优选地，报告证实了外周动脉疾病的不存在或存在（和/或严重性），包括定量数据。血液动力学系统和成像系统可以直接，间接和/或无线地进行通信。它们可以包含在公共外壳内和/或被集成到单个设备中。血液动力学系统和/或成像系统中的任一个或两者也可以被配置成测量患者的血压。优选地，成像系统是超声成像系统，并且用于诊断外周动脉疾病结果的改进的工作流程。

23. 发明授权

US07846106B2 Atrial fibrillation detection using SPO2 有权
标题翻译：使用SPO2进行心房颤动检测
公开(公告)号：US07846106B2
公开(公告)日：2010-12-07
申请号：US11411714
申请日：2006-04-26
申请人： Angela Andrews , Bruce Friedman , Donald Brodnick , George Hutchinson
发明人： Angela Andrews , Bruce Friedman , Donald Brodnick , George Hutchinson
IPC分类号： A61B5/02
CPC分类号： A61B5/14551 , A61B5/02416 , A61B5/046 , A61B5/7207
摘要： The method and system includes detecting atrial fibrillation in a patient by monitoring the blood oxygen saturation level over a period of time. The method and system produces a plethysmographic waveform from the monitored blood oxygen saturation level and analyzes the plethysmographic waveform and detected intervals and determines whether the patient is in atrial fibrillation. The method and system is preferably implemented in a software application and may be configured to report to the user on the current state of atrial fibrillation (AFIB) and a current trend.
摘要翻译：该方法和系统包括通过在一段时间内监测血氧饱和度水平来检测患者的房颤。该方法和系统从监测的血氧饱和度水平产生体积描记图波形，并分析体积描记波形和检测间隔，并确定患者是否处于心房颤动。该方法和系统优选地在软件应用中实现，并且可以被配置为向用户报告当前的房颤状态（AFIB）和当前趋势。

24. 发明申请

US20080281164A1 APPARATUS AND METHOD FOR A PATIENT MONITOR 审中-公开
标题翻译：患者监护仪的装置和方法
公开(公告)号：US20080281164A1
公开(公告)日：2008-11-13
申请号：US11747423
申请日：2007-05-11
申请人： Andrea Stebor , Bruce Friedman , John W. Booth
发明人： Andrea Stebor , Bruce Friedman , John W. Booth
IPC分类号： A61B5/00
CPC分类号： A61B5/02055 , A61B5/021 , A61B5/0402 , A61B5/0476 , A61B5/14551 , A61B5/7405 , A61B2560/04
摘要： A patient monitoring apparatus is disclosed herein. The patient monitoring apparatus includes a controller, and a speaker operatively connected to the controller. The speaker is configured to selectively produce a sound adapted to audibly entertain, distract and/or soothe a patient such that the patient can be conveniently and accurately monitored. A corresponding method for monitoring one or more of a patient's vital signs is also provided.
摘要翻译：本文公开了一种患者监测装置。患者监视装置包括控制器和可操作地连接到控制器的扬声器。扬声器被配置为选择性地产生适于听觉地娱乐，分散和/或抚慰患者的声音，使得可以方便和准确地监视患者。还提供了用于监测患者生命体征中的一个或多个的相应方法。

25. 发明申请

US20080243009A1 METHOD OF CONTROLLING INFLATION OF A CUFF IN BLOOD PRESSURE DETERMINATION 审中-公开
标题翻译：控制血压在血压测定中的运动方法
公开(公告)号：US20080243009A1
公开(公告)日：2008-10-02
申请号：US11694178
申请日：2007-03-30
申请人： Lawrence T. Hersh , Sai Kolluri , Bruce Friedman , Richard Medero
发明人： Lawrence T. Hersh , Sai Kolluri , Bruce Friedman , Richard Medero
IPC分类号： A61B5/02
CPC分类号： A61B5/02255 , A61B5/02225
摘要： The present application discloses a method of calculating an initial inflation pressure during a blood pressure determination using an NIB system. The cuff provided with the system is inflated towards a default initial inflation pressure and a plurality of oscillometric pulses are obtained during inflation. A quick systolic pressure is estimated from a pre-defined function having a physiologically- expected shape of an oscillometric envelope fitted to oscillometric data obtained during the inflation. In an embodiment, the parameters within the function are specifically found by fitting a plurality of oscillometric pulse amplitudes along with their corresponding cuff pressures obtained during inflation to the pre-defined function. The cuff is inflated up to a calculated initial inflation pressure, which is found from the estimated quick systolic pressure. After the cuff is brought to the initial inflation pressure, deflation is begun for determining the actual systolic and diastolic pressures for output to a user.
摘要翻译：本申请公开了一种使用NIB系统计算在血压测定期间的初始充气压力的方法。提供有系统的袖带朝向默认的初始充气压力充气，并且在充气期间获得多个示波脉冲。从预先定义的功能估计出快速的收缩压，该功能具有适应于在充气期间获得的示波数据的示波包络的生理预期形状。在一个实施例中，功能中的参数通过将多个示波脉冲幅度及其在充气期间获得的相应袖带压力拟合到预定义功能而具体发现。袖带充气到计算的初始充气压力，这是从估计的快速收缩压中发现的。在袖带被带到初始通货膨胀压力之后，开始通货紧缩来确定输出给用户的实际收缩压和舒张压。

26. 发明申请

US20080082007A1 METHOD FOR MONITORING PRE-ECLAMPTIC PATIENTS 失效
标题翻译：监测预激活患者的方法
公开(公告)号：US20080082007A1
公开(公告)日：2008-04-03
申请号：US11948564
申请日：2007-11-30
申请人： Bruce Friedman
发明人： Bruce Friedman
IPC分类号： A61B5/0205 , A61B5/02
CPC分类号： A61B5/022 , A61B5/02225 , A61B5/082
摘要： A system and method for monitoring and estimating the blood pressure of a pregnant patient that modifies the blood pressure estimating algorithm when the patient is pre-eclamptic. The level of carbon monoxide within a patient's bloodstream or exhaled breath can be analyzed to determine whether a pregnant patient is pre-eclamptic. After the patient has been diagnosed as pre-eclamptic, the NIBP monitoring system adjusts its algorithm for estimating the patient's blood pressure to compensate for the physical changes that occur in the patient during pre-eclampsia. The adjusted blood pressure estimates calculated by the NIBP monitoring system can be calculated using different adjustment techniques and methods and are displayed on the NIBP monitor.
摘要翻译：一种用于监测和估计怀孕患者的血压的系统和方法，所述系统和方法在患者是先兆子痫时修改血压估计算法。可以分析患者血液或呼出气中的一氧化碳水平，以确定怀孕患者是否为先兆子痫。在患者被诊断为先兆子痫之后，NIBP监测系统调整其估计患者血压的算法，以补偿患者先兆子痫期间发生的物理变化。由NIBP监控系统计算出的调整血压估计可以使用不同的调整技术和方法进行计算，并显示在NIBP监视器上。

27. 发明授权

US6050951A NIBP trigger in response to detected heart rate variability 失效
标题翻译： NIBP触发响应于检测到的心率变异性
公开(公告)号：US6050951A
公开(公告)日：2000-04-18
申请号：US966719
申请日：1997-11-10
申请人： Bruce Friedman , Lawrence T. Hersh , Richard Medero
发明人： Bruce Friedman , Lawrence T. Hersh , Richard Medero
IPC分类号： A61B5/022 , A61N5/00
CPC分类号： A61B5/02405 , A61B5/022 , A61B5/02225 , A61B5/7285 , Y10S128/90
摘要： An automated sphygmomanometer which triggers a blood pressure determination upon detection of a significant change in the patient's heart rate variability (HRV). The HRV can be measured directly from the NIBP signal or, when a multiparameter monitor is used, the HRV can be measured from the ECG signal or the NIBP signal. HRV is continuously monitored and the baseline HRV is correlated with baseline blood pressure values. Changes in HRV are displayed continuously on a display so that the clinician can determine whether to initiate an NIBP measurement or, on the other hand, the NIBP measurement can be triggered automatically in response to a change in HRV without any intervention by the clinician. Alternatively, the patient monitor can "learn" the correlation between HRV and blood pressure changes and only alert the clinician when a significant change in HRV has taken place. The technique of the invention allows the clinician to monitor NIBP at less frequent intervals without the concern of missing physiologically significant changes in blood pressure and without the requirement of "check inflates" in a guard mode.
摘要翻译：一种自动血压计，其在检测到患者心率变异性（HRV）的显着变化时触发血压测定。可以直接从NIBP信号测量HRV，或者当使用多参数监视器时，可以从ECG信号或NIBP信号测量HRV。持续监测HRV，基线HRV与基线血压值相关。在显示器上连续显示HRV的变化，以便临床医生可以确定是否启动NIBP测量，或者另一方面可以响应于HRV的变化而自动地触发NIBP测量，而无需临床医师的任何干预。或者，患者监护仪可以“学习”HRV与血压变化之间的相关性，并且只有在发生HRV的显着变化时才向临床医生发出警报。本发明的技术允许临床医生以不太频繁的间隔监测NIBP，而不考虑血压的生理学显着变化，并且不需要在保护模式下“检查膨胀”。

28. 发明申请

US20120198341A1 System and Method of Automatic Scaling of Clinical Data for Varied Display Size 审中-公开
标题翻译：自动缩放不同显示尺寸临床数据的系统和方法
公开(公告)号：US20120198341A1
公开(公告)日：2012-08-02
申请号：US13015840
申请日：2011-01-28
申请人： Matthew R. Pekarske , Michael J. Palmer , Brian Bayer , Bruce Friedman , Antti Ylostalo , David Meier
发明人： Matthew R. Pekarske , Michael J. Palmer , Brian Bayer , Bruce Friedman , Antti Ylostalo , David Meier
IPC分类号： G06F3/048
CPC分类号： G06F3/04886 , G06F3/0481 , G06F19/3418 , G06F2203/04803 , G16H40/63
摘要： The system and method of the present application allows for the configurable display of a number of physiological parameters on a wide variety of display sizes, usually those displays that are smaller than the bedside monitor display. The system and method organizes data in a grid of displayable elements, each displayable element including a piece of information corresponding to a collected physiological parameter of a patient. Depending upon the size of the display, an appropriate number of displayable elements are organized in a grid on the display and the size of each grid on the display is configurable and adjustable by a user.
摘要翻译：本申请的系统和方法允许在各种各样的显示器尺寸（通常是比床边显示器显示器小的显示器）上可配置地显示多个生理参数。该系统和方法将数据组织在可显示元件的网格中，每个可显示元素包括对应于患者的收集的生理参数的一条信息。根据显示器的尺寸，适当数量的可显示元件被组织在显示器上的网格中，并且显示器上的每个网格的大小可由用户配置和调节。

29. 发明授权

US5704362A Method for oscillometric blood pressure determination employing curve fitting 失效
标题翻译：使用曲线拟合的示波血压测定方法
公开(公告)号：US5704362A
公开(公告)日：1998-01-06
申请号：US106280
申请日：1993-08-13
申请人： Lawrence T. Hersh , Bruce Friedman , Richard Medero
发明人： Lawrence T. Hersh , Bruce Friedman , Richard Medero
IPC分类号： G06F19/00 , G06K9/00 , A61B5/00
CPC分类号： G06K9/00536
摘要： A method of measuring blood pressure where a plurality of oscillometric data values are measured from a subject at a plurality pressure levels, a function curve having the shape of an oscillometric envelope is selected and computational model fit to the data, using the Gauss-Marquardt method of model fitting. Once the curve is model fit, blood pressure is measured using the oscillometric method. Included in the step of model fitting is the step of computing the parameter of the function curve that minimizes the error between the function curve and the data values at the respective pressure levels thereby approximating the oscillometric envelope based upon data values.
摘要翻译：一种测量血压的方法，其中从多个压力水平上的对象测量多个示波数据值，选择具有示波包络形状的函数曲线，并使用高斯 - 马夸特方法对计算模型拟合数据的模型拟合。曲线拟合后，使用示波法测量血压。包括在模型拟合步骤中的步骤是计算函数曲线的参数的步骤，其使功能曲线和各压力水平下的数据值之间的误差最小化，从而基于数据值近似示波包络。

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