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1. 发明申请

US20080243009A1 METHOD OF CONTROLLING INFLATION OF A CUFF IN BLOOD PRESSURE DETERMINATION 审中-公开
标题翻译：控制血压在血压测定中的运动方法
公开(公告)号：US20080243009A1
公开(公告)日：2008-10-02
申请号：US11694178
申请日：2007-03-30
申请人： Lawrence T. Hersh , Sai Kolluri , Bruce Friedman , Richard Medero
发明人： Lawrence T. Hersh , Sai Kolluri , Bruce Friedman , Richard Medero
IPC分类号： A61B5/02
CPC分类号： A61B5/02255 , A61B5/02225
摘要： The present application discloses a method of calculating an initial inflation pressure during a blood pressure determination using an NIB system. The cuff provided with the system is inflated towards a default initial inflation pressure and a plurality of oscillometric pulses are obtained during inflation. A quick systolic pressure is estimated from a pre-defined function having a physiologically- expected shape of an oscillometric envelope fitted to oscillometric data obtained during the inflation. In an embodiment, the parameters within the function are specifically found by fitting a plurality of oscillometric pulse amplitudes along with their corresponding cuff pressures obtained during inflation to the pre-defined function. The cuff is inflated up to a calculated initial inflation pressure, which is found from the estimated quick systolic pressure. After the cuff is brought to the initial inflation pressure, deflation is begun for determining the actual systolic and diastolic pressures for output to a user.
摘要翻译：本申请公开了一种使用NIB系统计算在血压测定期间的初始充气压力的方法。提供有系统的袖带朝向默认的初始充气压力充气，并且在充气期间获得多个示波脉冲。从预先定义的功能估计出快速的收缩压，该功能具有适应于在充气期间获得的示波数据的示波包络的生理预期形状。在一个实施例中，功能中的参数通过将多个示波脉冲幅度及其在充气期间获得的相应袖带压力拟合到预定义功能而具体发现。袖带充气到计算的初始充气压力，这是从估计的快速收缩压中发现的。在袖带被带到初始通货膨胀压力之后，开始通货紧缩来确定输出给用户的实际收缩压和舒张压。

2. 发明授权

US07288070B2 Method and apparatus for determining extreme blood pressure values 失效
标题翻译：用于确定极端血压值的方法和装置
公开(公告)号：US07288070B2
公开(公告)日：2007-10-30
申请号：US10847934
申请日：2004-05-18
申请人： Sai Kolluri , Lawrence T. Hersh , Bruce Friedman , Richard Medero
发明人： Sai Kolluri , Lawrence T. Hersh , Bruce Friedman , Richard Medero
IPC分类号： A61B5/02 , A61B5/04
CPC分类号： A61B5/02225 , A61B5/0225 , A61B5/0456
摘要： In a method and apparatus for measuring extreme blood pressure values during a single non-invasive blood measurement, the time intervals between sequential heartbeats are measured for a series of heartbeats in an oscillometric blood pressure measurement time period. Oscillometric blood pressure measurement data for the heartbeats of the series is obtained and associated with the heartbeat time intervals. An average time interval between heartbeats is also determined. A first data bin may be defined for blood pressure data associated with time intervals that are longer as compared to the average time interval. A second data bin is defined for blood pressure data with time intervals that are shorter as compared to the average time interval. The measured oscillometric blood pressure data is sorted into the data bins in accordance with the associated time intervals. The data in the first data bin is used to derive a high systolic blood pressure value and a low diastolic blood pressure value. The data in the second bin is used to derive a low systolic blood pressure value and a high diastolic blood pressure value. A typical blood pressure value may also be determined.
摘要翻译：在用于在单次非侵入性血液测量期间测量极端血压值的方法和装置中，测量在示波血压测量时间段内的一系列心跳的连续心跳之间的时间间隔。获得该系列心跳的示波血压测量数据，并与心跳时间间隔相关联。心跳之间的平均时间间隔也被确定。可以为与与平均时间间隔相比较长的时间间隔相关联的血压数据定义第一数据箱。第二个数据仓被定义为与平均时间间隔相比时间间隔更短的血压数据。测量的示波血压数据根据相关联的时间间隔被分类到数据箱中。第一数据箱中的数据用于导出高收缩压值和低舒张压值。第二个仓中的数据用于导出低收缩压值和高舒张压值。也可以确定典型的血压值。

3. 发明申请

US20100174202A1 METHOD AND SYSTEM FOR COMBINING OSCILLOMETRIC BLOOD PRESSURE ENVELOPE DATA OBTAINED FROM DIFFERENT SIGNAL PROCESSING PATHS 审中-公开
标题翻译：用于组合来自不同信号处理程序的OSCILOMETRIC BLOOD压力包数据的方法和系统
公开(公告)号：US20100174202A1
公开(公告)日：2010-07-08
申请号：US12350412
申请日：2009-01-08
申请人： Lawrence T. Hersh , Sai Kolluri , Bruce A. Friedman , Richard Medero
发明人： Lawrence T. Hersh , Sai Kolluri , Bruce A. Friedman , Richard Medero
IPC分类号： A61B5/0225
CPC分类号： A61B5/0225 , A61B5/02225 , A61B5/0402 , A61B5/1455
摘要： A blood pressure measurement system that utilizes a non-invasive blood pressure (NIBP) monitor having a blood pressure cuff and pressure transducer. The measurement system provides a plurality of separate processing techniques that each receive a plurality of oscillometric waveform sample values generated using the pressure transducer. Each of the processing techniques separately generates a set of envelope points based upon the oscillometric data values. The sets of envelope points are appropriately scaled such that the sets of scaled envelope points are combined with each other to create a set of combined, scaled envelope points. Various different methods can be used to scale the sets of envelope points prior to the combination of the scaled envelope points. Based upon the combination of scaled envelope points, the blood pressure is calculated and displayed by the NIBP monitor.
摘要翻译：一种血压测量系统，其利用具有血压袖带和压力换能器的非侵入性血压（NIBP）监测器。测量系统提供多个单独的处理技术，每个处理技术接收使用压力传感器产生的多个示波波形采样值。每个处理技术基于示波器数据值分别产生一组包络点。适当地缩放包络点集合，使得缩放包络点的集合彼此组合以创建一组组合的，缩放的包络点。可以使用各种不同的方法在缩放的包络点的组合之前缩放包络点集合。根据缩放的包络点的组合，由NIBP监视器计算和显示血压。

4. 发明授权

US06648828B2 Continuous, non-invasive technique for measuring blood pressure using impedance plethysmography 有权
标题翻译：使用阻抗体积描记法测量血压的连续，非侵入性技术
公开(公告)号：US06648828B2
公开(公告)日：2003-11-18
申请号：US09683916
申请日：2002-03-01
申请人： Bruce A. Friedman , Richard Medero , Lawrence T. Hersh , Sai Kolluri
发明人： Bruce A. Friedman , Richard Medero , Lawrence T. Hersh , Sai Kolluri
IPC分类号： A61B502
CPC分类号： A61B5/0285 , A61B5/021 , A61B5/02125 , A61B5/0295
摘要： Blood pressure is measured using the pulse transit time required for the blood volume pulse to propagate between two locations in an animal. Impedance plethysmography is employed to detect when the blood volume pulse occurs at one location. The plethysmograph may detect thoracic impedance to determine when the aortic heart valve opens or it may detect impedance at one location on a limb of the animal. Occurrence of the blood volume pulse at another location can be determined by impedance plethysmography or another technique, such as pulse oximetry. The calculation of cardiac stroke volume can be employed to compensate the derivation of the blood pressure for effects due to blood vessel compliance. A nonblood pressure monitor may periodically provide a reference blood pressure measurement that is used calibrate derivation of the blood pressure based on the pulse transit time.
摘要翻译：使用血液体积脉冲在动物的两个位置之间传播所需的脉搏传播时间来测量血压。采用阻抗体积描记法检测血液体积脉搏何时出现在一个位置。体积描记器可以检测胸部阻抗以确定主动脉瓣心脏瓣膜何时打开，或者可以在动物肢体的一个位置处检测阻抗。可以通过阻抗体积描记法或其他技术（例如脉搏血氧测定法）来确定另一位置处的血容量脉冲的发生。心脏搏动量的计算可用于补偿由于血管依从性引起的血压的推导。非血压监视器可以周期性地提供参考血压测量，其用于基于脉冲传播时间来校准血压的推导。

5. 发明申请

US20080235058A1 VITAL SIGN MONITOR UTILIZING HISTORIC PATIENT DATA 审中-公开
标题翻译： VITAL SIGN MONITOR使用历史患者数据
公开(公告)号：US20080235058A1
公开(公告)日：2008-09-25
申请号：US12133922
申请日：2008-06-05
申请人： Bruce A. Friedman , John W. Booth , Richard Medero , Lawrence T. Hersh , Sai Kolluri
发明人： Bruce A. Friedman , John W. Booth , Richard Medero , Lawrence T. Hersh , Sai Kolluri
IPC分类号： G06Q50/00
CPC分类号： A61B5/022 , A61B5/0205 , A61B5/02225 , A61B5/0225 , A61B5/024 , G06Q50/24
摘要： A vital sign monitoring system that can be used with multiple patients and utilizes historic patient data information for the patient to optimize the process of obtaining current vital sign measurements. Each patient is identified with a unique patient identification device that is automatically detected by the vital sign monitor. The vital sign monitor communicates with a medical records database and obtains historic patient data information and previously diagnosed characteristics for the patient identified by the patient identification device. The historic patient data information and previously diagnosed characteristics of the patient can be utilized by the vital sign monitor to set alarm limits for the vital sign measurements and automatically adjust the blood pressure estimation algorithm of the NIBP monitor.
摘要翻译：一个生命体征监测系统，可与多个患者一起使用，并利用患者的历史患者数据信息来优化获取当前生命体征测量的过程。每个患者都有一个唯一的患者识别装置，由生命体征监测器自动检测。生命体征监测器与医疗记录数据库进行通信，并获得由患者识别装置识别的患者的历史患者数据信息和先前诊断的特征。患者的历史患者数据信息和先前诊断的特征可由生命体征监测器用于设置生命体征测量的报警限值，并自动调整NIBP监测器的血压估计算法。

6. 发明授权

US07300404B1 Method and system utilizing SpO2 plethysmograph signal to qualify NIBP pulses 失效
标题翻译：使用SpO2体积描记器信号来限定NIBP脉冲的方法和系统
公开(公告)号：US07300404B1
公开(公告)日：2007-11-27
申请号：US11470701
申请日：2006-09-07
申请人： Sai Kolluri , Lawrence T. Hersh , Richard Medero
发明人： Sai Kolluri , Lawrence T. Hersh , Richard Medero
IPC分类号： A61B5/00
CPC分类号： A61B5/02255 , A61B5/02225
摘要： A method and system for operating a non-invasive blood pressure monitor that utilizes an SpO2 plethysmographic signal to reduce the time required to obtain an estimation of a patient's blood pressure. During operation of the NIBP monitor, the NIBP monitor utilizes the SpO2 plethysmographic signal to determine a timing period and a deflation period for each pulse associated with the patient's heartbeat. Upon receiving an oscillation pulse, the NIBP monitor determines the oscillation amplitude during the timing period and deflates the blood pressure cuff during the deflation period immediately following the timing period. Preferably, the deflation period occurs during the same oscillation pulse used to calculate the oscillation pulse amplitude to decrease the amount of time required to obtain a blood pressure estimate from the patient.
摘要翻译：一种用于操作使用SpO 2体积描记信号的非侵入性血压监测器的方法和系统，以减少获得对患者血压的估计所需的时间。在NIBP监视器的操作期间，NIBP监视器利用SpO 2体积描记信号来确定与患者心跳相关联的每个脉冲的定时周期和放气周期。在接收到振荡脉冲时，NIBP监视器确定定时期间的振荡幅度，并且在定时周期之后的放气期间缩小血压袖带。优选地，放气周期发生在用于计算振荡脉冲幅度的相同振荡脉冲期间，以减少从患者获得血压估计所需的时间量。

7. 发明授权

US06893403B2 Oscillometric determination of blood pressure 失效
标题翻译：示波测定血压
公开(公告)号：US06893403B2
公开(公告)日：2005-05-17
申请号：US10374240
申请日：2003-02-25
申请人： Sai Kolluri , Lawrence T. Hersh , Richard Medero
发明人： Sai Kolluri , Lawrence T. Hersh , Richard Medero
IPC分类号： A61B5/022 , A61B5/00
CPC分类号： A61B5/02225
摘要： A method and system for eliminating artifacts in an oscillation envelope are disclosed. The method and system comprise evaluating conformance of the oscillometric envelope blood pressure data with a predetermined expected pattern and excluding one or more data points of the oscillometric envelope blood pressure data based on non-conformance with the expected pattern. The expected pattern is based upon generally known physiological principles relating to oscillometric envelopes, a curve fit representing an oscillometric envelope from a previous determination, or other types of criteria.
摘要翻译：公开了一种用于消除振荡包络中的假象的方法和系统。所述方法和系统包括评估所述示波包络血压数据与预定预期模式的一致性，并且基于与所述期望模式的不一致性排除所述示波包络血压数据的一个或多个数据点。预期模式基于与示波包络相关的通常已知的生理原理，表示来自先前确定的示波包络的曲线拟合或其他类型的标准。

8. 发明授权

US06746403B2 Physiological-signal-analysis device for measuring a blood pressure and method 有权
标题翻译：用于测量血压和方法的生理信号分析装置
公开(公告)号：US06746403B2
公开(公告)日：2004-06-08
申请号：US09683911
申请日：2002-03-01
申请人： Sai Kolluri , Lawrence T. Hersh , Richard Medero
发明人： Sai Kolluri , Lawrence T. Hersh , Richard Medero
IPC分类号： A61B502
CPC分类号： A61B5/02225 , A61B5/021 , A61B5/02416 , A61B5/0402
摘要： A physiological-signal-analysis device for determining a blood pressure value of a patient and a method of operating the device. The device includes a cuff attachable to an extremity of the patient, a pneumatic system connected to the cuff that supplies a fluid to the cuff, a pressure transducer that measures the pressure signal having pressure oscillations, and a control unit connected to the pneumatic system and the pressure transducer. The control unit is operable to acquire a first oscillation having a first fiducial point, acquire a second oscillation having a second fiducial point, calculate a time interval representing a time from the first fiducial point to the second fiducial point, decide against selecting the second oscillation when the time interval is not a substantial integral multiple of a nominal oscillation period, and calculate a blood pressure value based on selected oscillations.
摘要翻译：一种用于确定患者的血压值的生理信号分析装置和操作该装置的方法。该装置包括可连接到患者的末端的袖带，连接到袖带的气动系统，其向袖带提供流体，测量具有压力振荡的压力信号的压力传感器，以及连接到气动系统的控制单元，压力传感器。控制单元可操作地获取具有第一基准点的第一振荡，获取具有第二基准点的第二振荡，计算表示从第一基准点到第二基准点的时间的时间间隔，决定不选择第二振荡当时间间隔不是标称振荡周期的实质整数倍时，并且基于所选择的振荡来计算血压值。

9. 发明授权

US08282567B2 Method and system for determination of pulse rate 有权
标题翻译：脉率测定方法及系统
公开(公告)号：US08282567B2
公开(公告)日：2012-10-09
申请号：US11406201
申请日：2006-04-18
申请人： Sai Kolluri , Lawrence T. Hersh , Richard Medero
发明人： Sai Kolluri , Lawrence T. Hersh , Richard Medero
IPC分类号： A61B5/02
CPC分类号： A61B5/02225 , A61B5/02 , A61B5/022
摘要： A method and system for determining pulse rate of a patient are disclosed. The method and system include acquiring measured information for at least one pulse at a pressure step, determining and storing quality values for the at least one pulse at the pressure step, analyzing pulse matching criteria for the pressure step, and determining pulse rate based on the measured information, quality values, and pulse matching criteria.
摘要翻译：公开了一种用于确定患者脉搏率的方法和系统。该方法和系统包括在压力步骤获取至少一个脉冲的测量信息，确定并存储压力步骤中的至少一个脉冲的质量值，分析压力步骤的脉冲匹配准则，以及基于测量信息，质量值和脉冲匹配标准。

10. 发明授权

US07462152B2 Method and system utilizing SpO2 plethysmograph signal to reduce NIBP determination time 有权
标题翻译：方法和系统利用SpO2体积描记信号降低NIBP测定时间
公开(公告)号：US07462152B2
公开(公告)日：2008-12-09
申请号：US11470698
申请日：2006-09-07
申请人： Sai Kolluri , Lawrence T. Hersh , Richard Medero , Heather Menshouse
发明人： Sai Kolluri , Lawrence T. Hersh , Richard Medero , Heather Menshouse
IPC分类号： A61B5/02
CPC分类号： A61B5/02255 , A61B5/02225
摘要： A method and system for operating a non-invasive blood pressure monitor that utilizes an SpO2 plethysmographic signal to reduce the time required to obtain an estimation of a patient's blood pressure. During operation of the NIBP monitor, the NIBP monitor utilizes the SpO2 plethysmographic signal to determine a timing period and a deflation period for each pulse associated with the patient's heartbeat. Upon receiving an oscillation pulse, the NIBP monitor determines the oscillation amplitude during the timing period and deflates the blood pressure cuff during the deflation period immediately following the timing period. Preferably, the deflation period occurs during the same oscillation pulse used to calculate the oscillation pulse amplitude to decrease the amount of time required to obtain a blood pressure estimate from the patient.
摘要翻译：一种用于操作无创血压监测器的方法和系统，其利用SpO2体积描记信号来减少获得患者血压估计所需的时间。在NIBP监测器的操作期间，NIBP监测器利用SpO2体积描记器信号确定与患者心跳相关联的每个脉冲的定时周期和放气周期。在接收到振荡脉冲时，NIBP监视器确定定时期间的振荡幅度，并且在定时周期之后的放气期间缩小血压袖带。优选地，放气周期发生在用于计算振荡脉冲幅度的相同振荡脉冲期间，以减少从患者获得血压估计所需的时间量。

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