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11. 发明授权

US08182739B2 Process for producing concentric-circular-gradient functional material for biogenic use and apparatus for producing the same 失效
标题翻译：生产用生物同心圆梯度功能材料的方法及其制造方法
公开(公告)号：US08182739B2
公开(公告)日：2012-05-22
申请号：US12139105
申请日：2008-06-13
申请人： Michiharu Okano , Hiroshi Izui
发明人： Michiharu Okano , Hiroshi Izui
IPC分类号： B22F7/00
CPC分类号： A61F2/28 , A61C8/0012 , A61F2/3094 , A61F2/4644 , A61F2002/30004 , A61F2002/30118 , A61F2002/3024 , A61F2002/30957 , A61F2002/30971 , A61F2230/0006 , A61F2230/0069 , A61F2250/0014 , A61F2310/00023 , A61F2310/00293 , A61L27/06 , A61L27/12 , A61L27/50 , B22F3/10 , B22F2999/00 , B30B15/302 , C04B35/447 , C22C29/12 , C22C32/0089 , B22F2207/01 , B22F2202/13
摘要： A concentric-circular-gradient functional material for biogenic use is produced using first, second, third and forth cylindrical partitions, and a cylindrical dice which are concentrically stood on a supporting stand. Ti powder (A) fills the first cylindrical partition. A first mixed powder including Ti powder (A) and biogenic material powder (B) fills between the first and second cylindrical partitions. A second mixed powder including a smaller amount of Ti powder (A) than the first mixed powder fills between the second and third cylindrical partitions. A third mixed powder including a smaller amount of Ti powder (A) than the second mixed powder fills between the third and fourth cylindrical partitions. The biogenic material powder (B) fills between the fourth cylindrical partition and the dice. The first to fourth partitions are pulled out. The dice is capped using a punch. The powders are sintered using a discharge plasma sintering machine.
摘要翻译：使用第一，第二，第三和第四圆柱形分隔件和同心地站在支撑架上的圆柱形骰子产生用于生物来源的同心圆梯度功能材料。 Ti粉末（A）填充第一圆柱形分隔物。包括Ti粉末（A）和生物原料粉末（B）的第一混合粉末填充在第一和第二圆柱形分隔件之间。包含比第一混合粉末少的Ti粉末（A）的第二混合粉末填充在第二和第三圆柱形分隔件之间。包含比第二混合粉末少的Ti粉末（A）的第三混合粉末填充在第三和第四圆柱形分隔件之间。生物源材料粉末（B）填充在第四圆柱形分隔件和骰子之间。第一至第四个分区被拉出。骰子用打孔机盖住。使用放电等离子体烧结机烧结粉末。

12. 发明授权

US08168430B2 Method for preparation of hepatocyte using ES cell 有权
标题翻译：使用ES细胞制备肝细胞的方法
公开(公告)号：US08168430B2
公开(公告)日：2012-05-01
申请号：US12225411
申请日：2006-03-24
申请人： Toyohiko Ariga , Taiichiro Seki , Go Watanabe , Hiroto Nakashima , Yuichi Hasebe
发明人： Toyohiko Ariga , Taiichiro Seki , Go Watanabe , Hiroto Nakashima , Yuichi Hasebe
IPC分类号： C12N5/00 , A01N63/00
CPC分类号： C12N5/067 , A61K38/49 , C12N2501/113 , C12N2501/70 , C12N2506/03
摘要： This invention relates to an agent for promoting differentiation of an ES cell, preferably an agent for promoting differentiation of an ES cell into a hepatocyte or a prophylactic agent for teratoma, comprising uPA. Furthermore this invention relates to a method of promoting differentiation of an ES cell, preferably a method of promoting differentiation of an ES cell into a hepatocyte, comprising the step of contacting uPA with the ES cell, or a method of preparing a hepatocyte comprising the step of contacting uPA with an ES cell to differentiate the ES cell into a hepatocyte.
摘要翻译：本发明涉及一种用于促进ES细胞分化的试剂，优选用于促进ES细胞分化为肝细胞或用于畸胎瘤的预防药物的试剂，其包含uPA。此外，本发明涉及促进ES细胞分化的方法，优选促进ES细胞分化为肝细胞的方法，包括使uPA与ES细胞接触的步骤，或包含步骤将uPA与ES细胞接触以将ES细胞分化为肝细胞。

13. 发明申请

US20120012593A1 STRUCTURE AND MANUFACTURING METHOD FOR PRESSURE VESSEL 有权
标题翻译：压力容器结构与制造方法
公开(公告)号：US20120012593A1
公开(公告)日：2012-01-19
申请号：US13258986
申请日：2010-04-01
申请人： Natsuki Kuroiwa , Kentaro Kono , Takatade Usami , Goichi Ben , Kazuhiro Sakata
发明人： Natsuki Kuroiwa , Kentaro Kono , Takatade Usami , Goichi Ben , Kazuhiro Sakata
IPC分类号： B65D6/00
CPC分类号： B29C70/32 , B29L2031/7156 , F17C1/16 , F17C2209/2163 , Y02E60/321
摘要： A pressure vessel structure includes a vessel main body, and a grid layer provided on a periphery of the vessel main body and including a plurality of grid lines formed by intersecting strip-form raw materials so as to overlap alternately. Thus, a burst pressure of the pressure vessel is increased.
摘要翻译：压力容器结构包括容器主体和设置在容器主体的周边上的栅格层，并且包括多个由带状原料交替形成的网格线，以便交替重叠。因此，压力容器的爆破压力增加。

14. 发明授权

US08071842B2 Method of constructing novel higher plant and method of promoting the growth of higher plant 有权
标题翻译：构建新型高等植物的方法和促进高等植物生长的方法
公开(公告)号：US08071842B2
公开(公告)日：2011-12-06
申请号：US11883240
申请日：2006-02-01
申请人： Tadatake Oku , Toshiyuki Nishio , Ryu Kawachi , Hirotaka Chida , Aiko Nakazawa
发明人： Tadatake Oku , Toshiyuki Nishio , Ryu Kawachi , Hirotaka Chida , Aiko Nakazawa
IPC分类号： C12N15/30 , C12N15/52 , C12N15/82
CPC分类号： C07K14/415 , C12N15/8261 , Y02A40/146
摘要： The present invention provides a method of producing a higher plant having cytochrome c6 in the thylakoid space of chloroplast, which is characterized in that it comprises introducing a gene encoding a fused protein formed by adding a signal peptide consisting of 50 to 80 amino acid residues to a cytochrome c6 protein into the genome of a higher plant.
摘要翻译：本发明提供了一种在叶绿体类囊体中产生具有细胞色素c6的较高植物的方法，其特征在于，其包括将编码通过将由50至80个氨基酸残基组成的信号肽加成的融合蛋白的基因导入细胞色素c6蛋白进入高等植物的基因组。

15. 发明授权

US08064569B2 X-ray CT imaging apparatus and imaging control method therefor 有权
标题翻译： X射线CT成像装置及其成像控制方法
公开(公告)号：US08064569B2
公开(公告)日：2011-11-22
申请号：US12584150
申请日：2009-08-31
申请人： Yoshinori Arai , Takahiro Yoshimura , Hideki Yoshikawa
发明人： Yoshinori Arai , Takahiro Yoshimura , Hideki Yoshikawa
IPC分类号： A61B6/00
CPC分类号： A61B6/14 , A61B6/032 , A61B6/542 , A61B6/544
摘要： An X-ray CT imaging apparatus includes an X-ray generating section, an X-ray image capturing section, a supporting section, a holding section, a rotation driving section, and an X-ray controlling section, wherein the X-ray generating section generates an X-ray cone beam, the X-ray image capturing section detects the X-ray cone beam having passed through an object, the supporting section supports the X-ray generating section and the X-ray image capturing section with the object positioned therebetween, the holding section holds the object, the rotation driving section rotates the supporting section relatively to the object, and the X-ray controlling section alleviates an influence of a high X-ray absorption region, present inside the object, in the X-ray image capturing section by means of a control model formed based upon information on the high X-ray absorption region.
摘要翻译： X射线CT成像装置包括X射线产生部，X射线摄像部，支撑部，保持部，旋转驱动部，X射线控制部， X射线成像部生成X射线锥形束，X射线图像拍摄部检测已经穿过物体的X射线锥形束，支撑部将X射线产生部和X射线图像拍摄部与物体所述保持部保持所述物体，所述旋转驱动部使所述支撑部相对于所述物体旋转，并且所述X射线控制部减轻所述物体内部的高X射线吸收区域对所述X的影响通过基于关于高X射线吸收区域的信息形成的控制模型的射线图像捕获部分。

16. 发明申请

US20110086342A1 Hepatocellular Carcinoma-Associated Gene 审中-公开
标题翻译：肝细胞癌相关基因
公开(公告)号：US20110086342A1
公开(公告)日：2011-04-14
申请号：US10568533
申请日：2004-08-23
申请人： Mariko Esumi , Tadatoshi Takayama , Keiko Takagi
发明人： Mariko Esumi , Tadatoshi Takayama , Keiko Takagi
IPC分类号： C12Q1/68 , C07H21/04
CPC分类号： G01N33/57438 , C12Q1/6886 , C12Q2600/118 , C12Q2600/158
摘要： The present invention provides a method for evaluating cancer, which comprises the following steps of: (a) collecting total RNA from an analyte; (b) measuring the expression level of at least one gene selected from among the genes shown in Tables 1 to 8; and (c) evaluating cancer using the measurement result as an indicator.
摘要翻译：本发明提供了一种评估癌症的方法，包括以下步骤：（a）从分析物中收集总RNA; （b）测量表1〜8所示基因中至少一种基因的表达量; 和（c）使用测量结果作为指标评估癌症。

17. 发明授权

US07888014B2 Method of detecting Haemophilus influenzae type b, primer set and kit for the use in the method 失效
标题翻译：方法检测流感嗜血杆菌b型，引物组和试剂盒用于该方法
公开(公告)号：US07888014B2
公开(公告)日：2011-02-15
申请号：US11665566
申请日：2005-05-16
申请人： Mitsuko Seki , Hirotaka Torigoe
发明人： Mitsuko Seki , Hirotaka Torigoe
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/04
CPC分类号： C12Q1/701
摘要： The present invention provides a method of detecting Haemophilus influenzae, which enables accurate and rapid detection of H. influenzae, a primer set for detecting H. influenzae, and a kit for detecting H. influenzae. Nucleic acid amplification is carried out using the DNA of H. influenzae as a template, and also using the LAMP primers as shown in SEQ ID NOS: 1 to 5 given as examples of the present invention. Thus, the presence or absence of the amplified product is detected. When primers having sequences that are complementary to the sequences as shown in SEQ ID NOS: 1 to 5 are used, such primers are excellent in terms of detection sensitivity and promptness of detection, as well as specificity. In addition, as another example of the present invention, nucleic acid amplification is carried out using LAMP primers as shown in SEQ ID NOS: 43 to 47, and the presence or absence of the amplified product is detected. Thereby, H. influenzae Type b can be distinguished from other capsular serotype and non-encapsulated type H. influenzae, and it can be detected rapidly, simply, and accurately.
摘要翻译：本发明提供了一种检测流感嗜血杆菌的方法，其能够准确和快速地检测流感嗜血杆菌，用于检测流感嗜血杆菌的引物组和用于检测流感嗜血杆菌的试剂盒。使用流感嗜血杆菌的DNA作为模板进行核酸扩增，并且也使用如本发明的实施例给出的SEQ ID NO：1至5所示的LAMP引物。因此，检测到扩增产物的存在或不存在。当使用具有与SEQ ID NO：1至5所示的序列互补的序列的引物时，这种引物在检测灵敏度和检测时间以及特异性方面是优异的。此外，作为本发明的另一个实例，使用如SEQ ID NO：43至47所示的LAMP引物进行核酸扩增，并检测扩增产物的存在或不存在。因此，流感嗜血杆菌B型可以与其他荚膜血清型和非包囊型流感嗜血杆菌区分开来，可以快速，简便，准确地检测。

18. 发明授权

US07883477B2 Human body backbone measuring/displaying system 失效
标题翻译：人体骨干测量/显示系统
公开(公告)号：US07883477B2
公开(公告)日：2011-02-08
申请号：US11718368
申请日：2005-10-26
申请人： Eiichi Ichikawa , Morio Ichikawa
发明人： Eiichi Ichikawa , Morio Ichikawa
IPC分类号： A61B5/103 , A61B5/117 , G01C9/00 , G01C17/00 , G01C19/00
CPC分类号： A61B5/103 , A61B5/4561
摘要： A human spinal column measuring and displaying system includes a spinal column measuring apparatus capable of measuring bending or a circumflex (twist) angle of the spinal column of the human body as a detaching amount measuring data from a reference value, an input apparatus for inputting gender, height data of the measurement subject, an image processing apparatus for inputting the detaching amount measuring data from the spinal column measuring apparatus and data from the input apparatus and generating a three-dimensional spinal column image of the measurement subject based on the detaching amount measuring data and the gender, height data of the measurement subject, and a display apparatus for displaying an image data from the image processing apparatus. The system can calculate a measured data of three-dimensional coordinates and a circumflex angle of the spinal column by scanning a predetermined probe along the spinal column, and simulate a shape of the spinal column from the measured data to be able to display a three-dimensional pseudonymous spinal column image by utilizing computer graphics.
摘要翻译：人体脊柱测量和显示系统包括能够测量人体脊柱的弯曲或扭转（扭转）角度的脊柱测量装置，作为从参考值测量数据的分离量，用于输入性别的输入装置，测量对象的高度数据，用于从脊柱测量装置输入分离量测量数据的图像处理装置和来自输入装置的数据，并且基于分离量测量生成测量对象的三维脊柱图像数据和测量对象的性别，高度数据，以及用于从图像处理装置显示图像数据的显示装置。该系统可以通过沿着脊柱扫描预定的探针来计算脊柱的三维坐标和回旋角的测量数据，并且根据测量数据模拟脊柱的形状以能够显示三维坐标，利用计算机图形的三维假名脊柱图像。

19. 发明申请

US20100237142A1 PAPER CONTAINER 有权
标题翻译：纸容器
公开(公告)号：US20100237142A1
公开(公告)日：2010-09-23
申请号：US12733856
申请日：2009-06-29
申请人： Fujio Koeda , Toshinari Shimizu , Osamu Tuchida , Youhei Tominaga , Atsushi Tanaka , Yoshihiro Urano
发明人： Fujio Koeda , Toshinari Shimizu , Osamu Tuchida , Youhei Tominaga , Atsushi Tanaka , Yoshihiro Urano
IPC分类号： B65D5/72
CPC分类号： B65D5/067 , B65D5/068 , B65D5/745
摘要： Provided is a paper container including four body portion panels (4, 5, 6, 7) forming a cylindrical body portion having a square section, the paper container being configured so that upper ends of the body portion panels are continuously provided with a pair of gable roof-forming panels (13, 14), which include exterior top seal panels (17, 18) and are opposed to each other, and provided with a pair of gable wall-forming panels (21, 22), which include interior top seal panels (25, 26) and are opposed to each other, and any one of which serves as a spout and is to be opened, the gable wall-forming panels (21, 22) are folded out between the gable roof-forming panels (13, 14), and the exterior top seal panels (17, 18) and the interior top seal panels (25, 26) are heated and sealed with each other at a predetermined position so as to be hermetically sealed, in which: a seal width on a non-opening side (B) of a top seal portion (30), which is formed by heating and sealing the exterior top seal panels (17, 18) and the interior top seal panels (25, 26) with each other at the predetermined position, is larger than a seal width on an opening side (A) serving as the spout, the seal width being downwardly enlarged from the opening side (A) to the non-opening side (B); and top-portion lateral-fold-lines (11, 12) serving as boundaries between the gable roof-forming panels (13, 14) and the body portion panels (4, 6) are downwardly tilted from the opening side (A) to the non-opening side (B). With this configuration, it is possible to provide a paper container including a top seal portion easy to be grasped without deteriorating capability of opening with ease of the top seal portion.
摘要翻译：本发明提供一种纸容器，其包括形成具有正方形截面的圆筒体部的四个主体部分面板（4,5,6,7），所述纸容器构造成使得主体部分面板的上端连续设置有一对山形屋顶形成板（13,14），其包括外部顶部密封板（17,18）并且彼此相对，并且设置有一对山形壁形成板（21,22），其包括内部顶部密封板（25,26）并且彼此相对，并且其中任何一个用作喷口并且要打开，山形壁形成板（21,22）在山墙屋顶形成板（13,14），并且外部顶部密封面板（17,18）和内部顶部密封面板（25,26）在预定位置彼此加热和密封以便被密封，其中：a 在顶部密封部分（30）的非开口侧（B）上的密封宽度，其通过加热和密封外部顶部（17,18）和内部顶部密封面板（25,26）在预定位置处彼此大于作为喷口的开口侧（A）上的密封宽度，密封件宽度向下扩大从开口侧（A）到非开口侧（B）; 并且用作山墙屋顶形成板（13,14）和主体部分面板（4,6）之间的边界的顶部侧向折叠线（11,12）从开口侧（A）向下倾斜到非开口侧（B）。利用这种构造，可以容易地提供一种容易被抓住的顶部密封部分的纸容器，而不会使顶部密封部分容易地打开的能力下降。

20. 发明申请

US20100186756A1 MOUTH GUARD AND PROCESS FOR PRODUCING THE SAME 审中-公开
标题翻译：道具及其生产方法
公开(公告)号：US20100186756A1
公开(公告)日：2010-07-29
申请号：US12667009
申请日：2008-06-26
申请人： Hiroyasu Koizumi , Takayuki Miyahara
发明人： Hiroyasu Koizumi , Takayuki Miyahara
IPC分类号： A61C5/14 , B29C39/12
CPC分类号： A63B71/085 , A61C7/08 , A63B2209/00 , A63B2243/007 , A63B2244/102
摘要： A mouth guard with a uniform shape adapts to occlusion shapes and fits closely to teeth at an occlusion position. The mouth guard is attached to a maxillary tooth row. The mouth guard is formed from a continuous pore high-polymer material to have a characteristic that includes a plateau region of a stress to a compression strain. The mouth guard utilizes the characteristic to fit closely to the tooth rows at the occlusion portion between upper and lower tooth rows, to apply even stress to the tooth rows contacting the occlusion portion. As this result, the mouth guard provides an excellently close-fitting degree and high safety owing to high impact absorption power.
摘要翻译：具有均匀形状的口罩适合于闭塞形状，并且在闭塞位置与牙齿紧密配合。口罩附着于上颌牙排。口罩由连续孔高分子材料形成，具有包括压应变应力平台区的特征。嘴罩利用该特征，紧密地配合在上下齿列之间的阻塞部分处的齿排，以对与接合部分接触的齿排施加均匀的应力。因此，由于高冲击吸收能力，护罩提供了非常好的紧密度和高安全性。

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