会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 16. 发明申请
    • Hgf production accelerator containing heparin-like oligosaccharide
    • 含有肝素寡糖的Hgf生产促进剂
    • US20060293275A1
    • 2006-12-28
    • US10565301
    • 2005-03-28
    • Toshikazu NakamuraKunio MatsumotoKazuhiro Fukuta
    • Toshikazu NakamuraKunio MatsumotoKazuhiro Fukuta
    • A61K31/727
    • C08B37/0075A61K31/7016A61K31/702A61K31/715C07H11/00C08B37/0078C08L5/10C12P19/04
    • The present invention aims to provide an agent for promoting HGF production comprising, as an effective ingredient, a disaccharide comprised of an uronic acid residue (wherein an uronic acid means an iduronic acid or a glucuronic acid, and has the same meaning hereinafter) and a glucosamine residue that are connected by α1,4-glycosidic linkage or β1,4-glycosidic linkage, or an oligosaccharide of tri- to hexadeca-saccharides having a structure in which uronic acid residues and glucosamine residues are alternately and repeatedly connected by α1,4-glycosidic linkage or β1,4-glycosidic linkage, wherein at least one hydroxy group of the uronic acid residues and/or the glucosamine residues may be sulfated, alkylated, acylated or aminated, and/or the amino group at position 2 of at least one of the glucosamine residue(s) may be sulfated, alkylated or acylated, or a salt thereof. The agent of the present invention for promoting HGF production is useful to promote healing of damaged tissues or organs of a living body.
    • 本发明的目的在于提供一种促进HGF生产的试剂,其包含由糖醛酸残基(其中糖醛酸表示艾杜糖醛酸或葡糖醛酸,并且具有下述相同含义)的二糖作为有效成分,和 通过α1,4-糖苷键或β1,4-糖苷键连接的葡糖胺残基或具有其中糖醛酸残基和葡糖胺残基被α1,44交替并重复连接的结构的三十六碳糖的寡糖 - 糖苷键或β1,4-糖苷键,其中所述糖醛酸残基和/或所述葡糖胺残基的至少一个羟基可以被硫酸化,烷基化,酰化或胺化,和/或至少在第2位的氨基 一种或多种葡糖胺残基可被硫酸化,烷基化或酰化,或其盐。 用于促进HGF产生的本发明的药剂可用于促进活体损伤的组织或器官的愈合。