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11. 发明申请

US20060009785A1 Shape memory polymer medical device 有权
标题翻译：形状记忆聚合物医疗器械
公开(公告)号：US20060009785A1
公开(公告)日：2006-01-12
申请号：US11172668
申请日：2005-06-30
申请人： Duncan Maitland , William Benett , Jane Bearinger , Thomas Wilson , Ward Small , Daniel Schumann , Wayne Jensen , Jason Ortega , John Marion , Jeffrey Loge
发明人： Duncan Maitland , William Benett , Jane Bearinger , Thomas Wilson , Ward Small , Daniel Schumann , Wayne Jensen , Jason Ortega , John Marion , Jeffrey Loge
IPC分类号： A61B17/24
CPC分类号： A61B17/221 , A61B2017/00867 , A61B2017/22034 , A61B2017/2215 , A61B2017/2217
摘要： A system for removing matter from a conduit. The system includes the steps of passing a transport vehicle and a shape memory polymer material through the conduit, transmitting energy to the shape memory polymer material for moving the shape memory polymer material from a first shape to a second and different shape, and withdrawing the transport vehicle and the shape memory polymer material through the conduit carrying the matter.
摘要翻译：用于从管道中去除物质的系统。该系统包括使运输车辆和形状记忆聚合物材料通过导管的步骤，将能量传递到形状记忆聚合物材料，以将形状记忆聚合物材料从第一形状移动到第二形状和不同形状，并且将运送车辆和形状记忆聚合物材料通过导管携带物质。

12. 发明申请

US20070135907A1 Stent with expandable foam 审中-公开
标题翻译：支架可扩张泡沫
公开(公告)号：US20070135907A1
公开(公告)日：2007-06-14
申请号：US11606620
申请日：2006-11-29
申请人： Thomas Wilson , Duncan Maitland , Ward Small , Patrick Buckley , William Benett , Jonathan Hartman , David Saloner
发明人： Thomas Wilson , Duncan Maitland , Ward Small , Patrick Buckley , William Benett , Jonathan Hartman , David Saloner
IPC分类号： A61F2/06
CPC分类号： A61F2/06 , A61B17/12022 , A61B17/12031 , A61B17/12113 , A61B17/12118 , A61B17/1214 , A61B17/12181 , A61B2017/00867 , A61B2017/00871 , A61B2017/12054 , A61B2017/12072 , A61B2017/12077 , A61F2/82 , A61F2/95 , A61F2002/823
摘要： A stent for treating a physical anomaly. The stent includes a skeletal support structure for expanding in the physical anomaly and a shape memory material coupled to the skeletal support structure.
摘要翻译：用于治疗身体异常的支架。支架包括用于在物理异常中膨胀的骨架支撑结构和耦合到骨骼支撑结构的形状记忆材料。

13. 发明授权

US06379325B1 Opto-acoustic transducer for medical applications 失效
标题翻译：用于医疗应用的光学传感器
公开(公告)号：US06379325B1
公开(公告)日：2002-04-30
申请号：US09350494
申请日：1999-07-09
申请人： William Benett , Peter Celliers , Luiz Da Silva , Michael Glinsky , Richard London , Duncan Maitland , Dennis Matthews , Peter Krulevich , Abraham Lee
发明人： William Benett , Peter Celliers , Luiz Da Silva , Michael Glinsky , Richard London , Duncan Maitland , Dennis Matthews , Peter Krulevich , Abraham Lee
IPC分类号： A61B1720
CPC分类号： A61B18/26 , A61B17/2202 , A61B2017/00106 , A61B2017/22084 , A61B2090/378
摘要： This invention is an optically activated transducer for generating acoustic vibrations in a biological medium. The transducer is located at the end of a fiber optic which may be located within a catheter. Energy for operating the transducer is provided optically by laser light transmitted through the fiber optic to the transducer. Pulsed laser light is absorbed in the working fluid of the transducer to generate a thermal pressure and consequent adiabatic expansion of the transducer head such that it does work against the ambient medium. The transducer returns to its original state by a process of thermal cooling. The motion of the transducer within the ambient medium couples acoustic energy into the medium. By pulsing the laser at a high repetition rate (which may vary from CW to 100 kHz) an ultrasonic radiation field can be established locally in the medium. This method of producing ultrasonic vibrations can be used in vivo for the treatment of stroke-related conditions in humans, particularly for dissolving thrombus. The catheter may also incorporate anti-thrombolytic drug treatments as an adjunct therapy and it may be operated in conjunction with ultrasonic detection equipment for imaging and feedback control.
摘要翻译：本发明是用于在生物介质中产生声振动的光学激活换能器。传感器位于可以位于导管内的光纤的端部。用于操作换能器的能量由通过光纤传输到换能器的激光光学地提供。脉冲激光被吸收在换能器的工作流体中，以产生热压力并随之导致换能器头部的绝热膨胀，使其对环境介质起作用。传感器通过热冷却过程返回到其原始状态。传感器在环境介质中的运动将声能耦合到介质中。通过以高重复率脉冲激光（其可以从CW变化到100kHz），可以在介质中局部地建立超声辐射场。这种生产超声波振动的方法可以在体内用于治疗人类中风相关病症，特别是用于溶解血栓。导管还可以掺入抗血栓溶解药物治疗作为辅助治疗，并且其可以与用于成像和反馈控制的超声波检测设备结合操作。

14. 发明申请

US20060281101A1 Biobriefcase 审中-公开
标题翻译：生物百科全书
公开(公告)号：US20060281101A1
公开(公告)日：2006-12-14
申请号：US11154975
申请日：2005-06-15
申请人： John Dzenitis , William Benett , Raymond Mariella , Steven Visuri , Kodumudi Venkateswaran
发明人： John Dzenitis , William Benett , Raymond Mariella , Steven Visuri , Kodumudi Venkateswaran
IPC分类号： C12Q1/68 , G01N33/53 , C12M1/34
CPC分类号： G01N35/00 , B01L1/52 , B01L3/5027 , G01N1/28 , G01N33/543 , G01N2001/027
摘要： A bio-briefcase system for analyzing a sample for the presence of biological agents. The bio-briefcase system comprises a housing, an immunoassay section operatively connected to the housing, and/or a nucleic acid assay section operatively connected to the housing.
摘要翻译：用于分析样品存在生物制剂的生物公文包系统。生物公文包系统包括壳体，可操作地连接到壳体的免疫测定部分和/或可操作地连接到壳体的核酸测定部分。

15. 发明授权

US5944687A Opto-acoustic transducer for medical applications 失效
公开(公告)号：US5944687A
公开(公告)日：1999-08-31
申请号：US639018
申请日：1996-04-24
申请人： William Benett , Peter Celliers , Luiz Da Silva , Michael Glinsky , Richard London , Duncan Maitland , Dennis Matthews , Peter Krulevich , Abraham Lee
发明人： William Benett , Peter Celliers , Luiz Da Silva , Michael Glinsky , Richard London , Duncan Maitland , Dennis Matthews , Peter Krulevich , Abraham Lee
IPC分类号： A61B17/22 , A61B17/00 , A61B18/00 , A61B18/26 , A61B19/00 , A61B17/20
CPC分类号： A61B18/26 , A61B17/2202 , A61B2017/00106 , A61B2017/22084 , A61B2090/378
摘要： This invention is an optically activated transducer for generating acoustic vibrations in a biological medium. The transducer is located at the end of a fiber optic which may be located within a catheter. Energy for operating the transducer is provided optically by laser light transmitted through the fiber optic to the transducer. Pulsed laser light is absorbed in the working fluid of the transducer to generate a thermal pressure and consequent adiabatic expansion of the transducer head such that it does work against the ambient medium. The transducer returns to its original state by a process of thermal cooling. The motion of the transducer within the ambient medium couples acoustic energy into the medium. By pulsing the laser at a high repetition rate (which may vary from CW to 100 kHz) an ultrasonic radiation field can be established locally in the medium. This method of producing ultrasonic vibrations can be used in vivo for the treatment of stroke-related conditions in humans, particularly for dissolving thrombus. The catheter may also incorporate anti-thrombolytic drug treatments as an adjunct therapy and it may be operated in conjunction with ultrasonic detection equipment for imaging and feedback control.

16. 发明授权

US06368318B1 Opto-acoustic recanilization delivery system 失效
标题翻译：光声补偿输送系统
公开(公告)号：US06368318B1
公开(公告)日：2002-04-09
申请号：US09012379
申请日：1998-01-23
申请人： Steven R. Visuri , Luiz B. Da Silva , Peter M. Celliers , Richard A. London , William Benett , Kathryn Broughton , Victor Esch
发明人： Steven R. Visuri , Luiz B. Da Silva , Peter M. Celliers , Richard A. London , William Benett , Kathryn Broughton , Victor Esch
IPC分类号： A61B1818
CPC分类号： A61B18/26 , A61B18/245 , A61B2017/22061 , A61B2018/00029 , A61B2018/2211
摘要： Fiber delivered laser pulses emulsify thrombus by mechanical stresses that include a combination of pressure, tension and shear stress. Laser radiation is delivered to the locality of a thrombus and the radiation is absorbed by blood, blood dot, or other present materials. The combination of a leading pressure wave and subsequent vapor bubble cause efficient, emulsification of thrombus. Operating the laser in a low average power mode alleviates potential thermal complications. The laser is operated in a high repetition rate mode to take advantage of ultrasound frequency effects of thrombus dissolution as well as to decrease the total procedure time. Specific parameter ranges for operation are described. The device includes optical fibers surrounding a lumen intended for flow of a cooling agent. The fibers may be arranged concentrically around the lumen to deliver radiation and heat over as large an area as possible. An alternative design approach incorporates the optical fibers into the wall of the guiding catheter and utilizes the catheter lumen as the cooling channel. An eccentric tip enables rotation of the device to address all parts of the vasculature. The eccentricity can be provided via a variety of means: spring dip, balloon, protrusion, etc.
摘要翻译：纤维传递的激光脉冲通过机械应力乳化血栓，包括压力，张力和剪切应力的组合。激光辐射被输送到血栓的位置，并且辐射被血液，血液点或其他现有材料吸收。导致压力波和随后的蒸汽气泡的组合导致血栓的有效的乳化。以较低的平均功率模式操作激光可以减轻潜在的并发症。激光以高重复率模式运行，以利用血栓溶解的超声频率效应以及减少总的手术时间。描述操作的具体参数范围。该装置包括围绕用于冷却剂流动的内腔的光纤。纤维可以围绕内腔同心地布置，以在尽可能大的面积上传送辐射和热量。另一种设计方法将光纤结合到引导导管的壁中并利用导管内腔作为冷却通道。偏心的尖端能够使装置旋转以解决脉管系统的所有部分。偏心度可以通过各种方式提供：弹簧浸渍，气球，突起等

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