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1. 发明授权

US06368318B1 Opto-acoustic recanilization delivery system 失效
标题翻译：光声补偿输送系统
公开(公告)号：US06368318B1
公开(公告)日：2002-04-09
申请号：US09012379
申请日：1998-01-23
申请人： Steven R. Visuri , Luiz B. Da Silva , Peter M. Celliers , Richard A. London , William Benett , Kathryn Broughton , Victor Esch
发明人： Steven R. Visuri , Luiz B. Da Silva , Peter M. Celliers , Richard A. London , William Benett , Kathryn Broughton , Victor Esch
IPC分类号： A61B1818
CPC分类号： A61B18/26 , A61B18/245 , A61B2017/22061 , A61B2018/00029 , A61B2018/2211
摘要： Fiber delivered laser pulses emulsify thrombus by mechanical stresses that include a combination of pressure, tension and shear stress. Laser radiation is delivered to the locality of a thrombus and the radiation is absorbed by blood, blood dot, or other present materials. The combination of a leading pressure wave and subsequent vapor bubble cause efficient, emulsification of thrombus. Operating the laser in a low average power mode alleviates potential thermal complications. The laser is operated in a high repetition rate mode to take advantage of ultrasound frequency effects of thrombus dissolution as well as to decrease the total procedure time. Specific parameter ranges for operation are described. The device includes optical fibers surrounding a lumen intended for flow of a cooling agent. The fibers may be arranged concentrically around the lumen to deliver radiation and heat over as large an area as possible. An alternative design approach incorporates the optical fibers into the wall of the guiding catheter and utilizes the catheter lumen as the cooling channel. An eccentric tip enables rotation of the device to address all parts of the vasculature. The eccentricity can be provided via a variety of means: spring dip, balloon, protrusion, etc.
摘要翻译：纤维传递的激光脉冲通过机械应力乳化血栓，包括压力，张力和剪切应力的组合。激光辐射被输送到血栓的位置，并且辐射被血液，血液点或其他现有材料吸收。导致压力波和随后的蒸汽气泡的组合导致血栓的有效的乳化。以较低的平均功率模式操作激光可以减轻潜在的并发症。激光以高重复率模式运行，以利用血栓溶解的超声频率效应以及减少总的手术时间。描述操作的具体参数范围。该装置包括围绕用于冷却剂流动的内腔的光纤。纤维可以围绕内腔同心地布置，以在尽可能大的面积上传送辐射和热量。另一种设计方法将光纤结合到引导导管的壁中并利用导管内腔作为冷却通道。偏心的尖端能够使装置旋转以解决脉管系统的所有部分。偏心度可以通过各种方式提供：弹簧浸渍，气球，突起等

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