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    • 13. 发明授权
    • Intravascularly implantable integrated circuits
    • 血管内植入式集成电路
    • US07935056B2
    • 2011-05-03
    • US11731247
    • 2007-03-29
    • Mark J. Zdeblick
    • Mark J. Zdeblick
    • A61N1/08
    • A61N1/372A61B5/04011A61B5/0422A61N1/056A61N1/36185A61N1/368A61N1/3684A61N1/3686A61N1/37211A61N1/37276A61N1/37288A61N2001/0585
    • Techniques for controlling one or more modular circuits (“satellites”) that are intended for placement in a subject's body. The one or more satellites are controlled by sending signals over a bus that includes first and second conduction paths. Also coupled to the bus in system embodiments is a device such as a pacemaker that provides power and includes control circuitry. Each satellite includes satellite circuitry and one or more effectors that interact with the tissue. The satellite circuitry is coupled to the bus, and thus interfaces the controller to the one or more effectors, which may function as actuators, sensors, or both. The effectors may be electrodes that are used to introduce analog electrical signals (e.g., one or more pacing pulses) into the tissue in the local areas where the electrodes are positioned (e.g., heart muscles) or to sense analog signals (e.g., a propagating depolarization signal) within the tissue.
    • 用于控制用于放置在受检者体内的一个或多个模块化电路(“卫星”)的技术。 通过在包括第一和第二导电路径的总线上发送信号来控制一个或多个卫星。 在系统实施例中还耦合到总线的是诸如提供电力并包括控制电路的起搏器的装置。 每个卫星包括卫星电路和与组织相互作用的一个或多个效应器。 卫星电路耦合到总线,并且因此使控制器与一个或多个效应器接合,这些效应器可以用作致动器,传感器或两者。 效应器可以是用于将模拟电信号(例如,一个或多个起搏脉冲)引入电极定位的局部区域(例如,心脏肌肉)中的组织中或用于感测模拟信号(例如,传播 去极化信号)。
    • 16. 发明授权
    • Methods and apparatus for tissue activation and monitoring
    • 组织活化和监测的方法和装置
    • US08700148B2
    • 2014-04-15
    • US11731236
    • 2007-03-29
    • Mark J. Zdeblick
    • Mark J. Zdeblick
    • A61N1/372
    • A61N1/372A61B5/04011A61B5/0422A61N1/056A61N1/36185A61N1/368A61N1/3684A61N1/3686A61N1/37211A61N1/37276A61N1/37288A61N2001/0585
    • Techniques for controlling one or more modular circuits (“satellites”) that are intended for placement in a subject's body. The one or more satellites are controlled by sending signals over a bus that includes first and second conduction paths. Also coupled to the bus in system embodiments is a device such as a pacemaker that provides power and includes control circuitry. Each satellite includes satellite circuitry and one or more effectors that interact with the tissue. The satellite circuitry is coupled to the bus, and thus interfaces the controller to the one or more effectors, which may function as actuators, sensors, or both. The effectors may be electrodes that are used to introduce analog electrical signals (e.g., one or more pacing pulses) into the tissue in the local areas where the electrodes are positioned (e.g., heart muscles) or to sense analog signals (e.g., a propagating depolarization signal) within the tissue.
    • 用于控制用于放置在受检者体内的一个或多个模块化电路(“卫星”)的技术。 通过在包括第一和第二导电路径的总线上发送信号来控制一个或多个卫星。 在系统实施例中还耦合到总线的是诸如提供电力并包括控制电路的起搏器的装置。 每个卫星包括卫星电路和与组织相互作用的一个或多个效应器。 卫星电路耦合到总线,并且因此使控制器与一个或多个效应器接合,这些效应器可以用作致动器,传感器或两者。 效应器可以是用于将模拟电信号(例如,一个或多个起搏脉冲)引入电极定位的局部区域(例如,心脏肌肉)中的组织中或用于感测模拟信号(例如,传播 去极化信号)。
    • 19. 发明授权
    • Methods for configuring satellite electrodes
    • 配置卫星电极的方法
    • US07713194B2
    • 2010-05-11
    • US11731034
    • 2007-03-29
    • Mark J. Zdeblick
    • Mark J. Zdeblick
    • A61N1/08
    • A61N1/372A61B5/04011A61B5/0422A61N1/056A61N1/36185A61N1/368A61N1/3684A61N1/3686A61N1/37211A61N1/37276A61N1/37288A61N2001/0585
    • Techniques for controlling one or more modular circuits (“satellites”) that are intended for placement in a subject's body. The one or more satellites are controlled by sending signals over a bus that includes first and second conduction paths. Also coupled to the bus in system embodiments is a device such as a pacemaker that provides power and includes control circuitry. Each satellite includes satellite circuitry and one or more effectors that interact with the tissue. The satellite circuitry is coupled to the bus, and thus interfaces the controller to the one or more effectors, which may function as actuators, sensors, or both. The effectors may be electrodes that are used to introduce analog electrical signals (e.g., one or more pacing pulses) into the tissue in the local areas where the electrodes are positioned (e.g., heart muscles) or to sense analog signals (e.g., a propagating depolarization signal) within the tissue.
    • 用于控制用于放置在受检者体内的一个或多个模块化电路(“卫星”)的技术。 通过在包括第一和第二导电路径的总线上发送信号来控制一个或多个卫星。 在系统实施例中还耦合到总线的是诸如提供电力并包括控制电路的起搏器的装置。 每个卫星包括卫星电路和与组织相互作用的一个或多个效应器。 卫星电路耦合到总线,并且因此使控制器与一个或多个效应器接合,这些效应器可以用作致动器,传感器或两者。 效应器可以是用于将模拟电信号(例如,一个或多个起搏脉冲)引入电极定位的局部区域(例如,心脏肌肉)中的组织中或用于感测模拟信号(例如,传播 去极化信号)。
    • 20. 发明申请
    • DESIGN-RULE MEDIATED LEAD PLACEMENT
    • 设计规则介绍的铅排
    • US20090018632A1
    • 2009-01-15
    • US12171986
    • 2008-07-11
    • Mark J. ZdeblickOlivier Colliou
    • Mark J. ZdeblickOlivier Colliou
    • A61N1/05
    • A61N1/056A61N1/3627A61N1/36578
    • Aspects of the invention include design rule mediated lead placement methods. Also disclosed are methods of using the resultant positioned leads, e.g., e.g., during evaluation of tissue motion, such as of a cardiac tissue motion, e.g., heart wall motion, via electric tomography, are provided. Also provided are devices and systems for practicing the subject methods. In certain embodiments, innovative data processing and display protocols, as well as systems that provided for the same, are provided. The subject methods, devices and systems find use in a variety of different applications, such as cardiac related applications, e.g., cardiac resynchronization therapy, and other applications.
    • 本发明的方面包括设计规则介导的铅放置方法。 还公开了使用所得到的定位引线的方法,例如,例如在评估组织运动期间,例如通过电断层摄影术的心脏组织运动,例如心脏壁运动。 还提供了用于实践主题方法的装置和系统。 在某些实施例中,提供了创新的数据处理和显示协议以及为其提供的系统。 主题方法,装置和系统可用于各种不同的应用,例如心脏相关应用,例如心脏再同步治疗和其它应用。