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11. 发明申请

US20160215254A1 SYSTEM AND METHOD FOR LASER LYSIS 审中-公开
标题翻译：激光雷达系统和方法
公开(公告)号：US20160215254A1
公开(公告)日：2016-07-28
申请号：US14909195
申请日：2014-09-23
申请人： Deirdre MELDRUM , Shih-Hui (Joseph) CHAO , Thai TRAN , Laimonas BAUSKAS , Jeff HOUKAL , Andrew HATCH , Weimin GAO , David Wayne RICHARDSON
发明人： Deirdre Meldrum , Shih-Hui (Joseph) Chao , Thai Tran , Laimonas Kelbauskas , Jeff Houkal , Andrew Hatch , Weimin Gao , David Richardson
IPC分类号： C12M1/00 , G01N1/28 , C12Q1/68
CPC分类号： C12Q1/6806 , B01L3/0293 , B01L3/502761 , B01L2200/0668 , B01L2300/0816 , B01L2300/0829 , B01L2300/0864 , C12M47/06 , C12Q1/6841 , C12Q1/6848 , C12Q1/686 , G01N1/286 , G01N2001/2886 , C12Q2547/101
摘要： The present invention provides a system and method for lysing individual cells in situ, including the steps of capturing a tissue sample comprising a cellular content, subjecting the tissue sample to a stream of continuous fluid flow, lysing a selected area of the tissue sample with a laser, thereby releasing at least a portion of the cellular content from the tissue sample, recovering at least one target molecule from the cellular content in the stream, and processing the at least one target molecule.
摘要翻译：本发明提供了一种用于原位裂解个体细胞的系统和方法，包括以下步骤：捕获包含细胞内容物的组织样品，使组织样品经受连续流体流动的流动，将组织样品的选定区域用激光，从而从组织样品中释放至少一部分细胞含量，从流中的细胞含量回收至少一种靶分子，以及处理该至少一种靶分子。

12. 发明授权

US08849796B2 Search system using search subdomain and hints to subdomains in search query statements and sponsored results on a subdomain-by-subdomain basis 有权
标题翻译：搜索系统使用搜索子域和提示到子域中的搜索查询语句和赞助结果在子域名的子域
公开(公告)号：US08849796B2
公开(公告)日：2014-09-30
申请号：US13599688
申请日：2012-08-30
申请人： Ali Diab , Scott A. Gatz , Shyam Kapur , David Ku , Chuck Kung , Phu Hoang , Qi Lu , Lynne Pogue , Yuan Kui Shen , Norman Shi , Thai Tran , Eckart Walther , Jeff Weiner
发明人： Ali Diab , Scott A. Gatz , Shyam Kapur , David Ku , Chuck Kung , Phu Hoang , Qi Lu , Lynne Pogue , Yuan Kui Shen , Norman Shi , Thai Tran , Eckart Walther , Jeff Weiner
IPC分类号： G06F7/00 , G06F17/30
CPC分类号： G06F17/3087 , G06F17/30554 , G06F17/3056 , G06F17/30864 , G06F17/30967 , G06Q30/0256 , G06Q30/0261 , H04W4/025 , Y10S707/99933 , Y10S707/99934 , Y10S707/99935 , Y10S707/99936
摘要： A method and apparatus for generating search results including searching by subdomain and providing sponsored results by subdomain is provided. A search system according to embodiments of the present invention analyzes search queries to determine if they are to be routed to subdomains and presents results include sponsored hits sponsored on a subdomain by subdomain basis.
摘要翻译：提供了一种产生搜索结果的方法和装置，包括由子域搜索并由子域提供赞助结果。根据本发明的实施例的搜索系统分析搜索查询以确定它们是否被路由到子域并且呈现结果包括通过子域为基础在子域上资助的赞助的点击。

13. 发明授权

US08316078B2 Inter-domain communication system using remote procedure calls for message communications between applications in different domains 有权
标题翻译：使用远程过程调用的域间通信系统在不同域中的应用之间进行消息通信
公开(公告)号：US08316078B2
公开(公告)日：2012-11-20
申请号：US13251917
申请日：2011-10-03
申请人： Benjamin Charles Appleton , Steffen Meschkat , Thai Tran , Adam Sah , Zheng Wang , Adam Paul Schuck , James Robert Macgill
发明人： Benjamin Charles Appleton , Steffen Meschkat , Thai Tran , Adam Sah , Zheng Wang , Adam Paul Schuck , James Robert Macgill
IPC分类号： G06F15/16
CPC分类号： G06Q30/02 , H04L67/28
摘要： A computer-implemented method for performing inter-domain communication in a web browser includes receiving first data from a first domain at a router associated with one or more domains other than the first domain, identifying at the router the one or more domains for receiving data associated with the received data, and transmitting second data associated with the received data to the one or more domains.
摘要翻译：用于在web浏览器中执行域间通信的计算机实现的方法包括从与第一域以外的一个或多个域相关联的路由器处接收来自第一域的第一数据，在路由器处标识用于接收数据的一个或多个域与所接收的数据相关联，以及将与所接收的数据相关联的第二数据发送到所述一个或多个域。

14. 发明申请

US20100082243A1 Method and apparatus to select city name associated with street located on border of two cities 有权
标题翻译：选择与两个城市边界上的街道相关的城市名称的方法和装置
公开(公告)号：US20100082243A1
公开(公告)日：2010-04-01
申请号：US12286197
申请日：2008-09-29
申请人： Thai Tran
发明人： Thai Tran
IPC分类号： G01C21/26 , G06F3/048
CPC分类号： G01C21/3611
摘要： A method and apparatus for identifying correct city involving a street that borders on two or more cities for a navigation system. The navigation system identifies a correct city name associated with such a border street based on a direction of a vehicle travelling on the border street. In another aspect, the navigation system identifies a correct city name associated with such a border street based on a cursor point on the map image as to which side of the street and city is more proximate to the cursor point. Further, the navigation system identifies a correct city name associated with such a border street based on an address number as to whether it is an odd number or even number thereby determining the side of the street and city.
摘要翻译：一种用于识别与两个或更多个城市相邻的街道的正确城市的导航系统的方法和装置。导航系统基于在边境街道上行驶的车辆的方向来识别与这样的边界街道相关联的正确的城市名称。在另一方面，导航系统基于地图图像上的光标点来识别与这样的边界街道相关联的正确的城市名称，即街道和城市的哪一侧更靠近光标点。此外，导航系统基于关于是奇数还是偶数的地址号来识别与这样的边界街道相关联的正确的城市名称，从而确定街道和城市的一侧。

15. 发明申请

US20100023397A1 Video Promotion In A Video Sharing Site 审中-公开
标题翻译：视频分享网站中的视频推广
公开(公告)号：US20100023397A1
公开(公告)日：2010-01-28
申请号：US12508460
申请日：2009-07-23
申请人： Jonathan Goldman , Aaron Lee , Matthew Liu , Thai Tran
发明人： Jonathan Goldman , Aaron Lee , Matthew Liu , Thai Tran
IPC分类号： G06Q30/00 , G06F17/30 , G06F7/10
CPC分类号： G06Q30/0257 , G06F16/78 , G06Q30/02 , G06Q30/0249 , G06Q30/0255 , G06Q30/0256
摘要： A promoter wishing to promote video content on a video hosting website selects the video and associates it with an advertising creative. The promoter selects associated keywords and indicates financial terms for the promotion, for example by agreeing to a cost-per-click or cost-per-impression payment arrangement with the video hosting site. When a user of the video hosting site performs a search on the keywords (or similar words) associated with the promoted video, the video hosting website includes the creative for the promoted video with the other search results returned. The user can then select to view any of the search results or the promoted video identified by the creative. When the user clicks on the indicia for the promoted video, the video hosting site serves to the user a watch page on which the user views the promoted video. The promoter is charged according to the payment mechanism selected.
摘要翻译：希望在视频托管网站上宣传视频内容的促销者选择该视频并将其与广告创意相关联。促销者选择相关联的关键字并指示促销的财务条款，例如通过同意视频托管网站的每次点击费用或每次展示费用付款安排。当视频托管站点的用户对与推荐视频相关联的关键字（或类似单词）执行搜索时，视频托管网站包括所推出的视频的创意，并返回其他搜索结果。然后，用户可以选择查看由广告素材识别的任何搜索结果或促销视频。当用户点击促销视频的标记时，视频托管站点向用户提供用户观看推荐视频的观看页面。根据所选择的支付机制对该启动子进行充电。

16. 发明授权

US07640099B2 Method and apparatus for inputting data indicating tentative destination for navigation system 有权
标题翻译：用于输入表示用于导航系统的暂定目的地的数据的方法和装置
公开(公告)号：US07640099B2
公开(公告)日：2009-12-29
申请号：US11732564
申请日：2007-04-04
申请人： Thai Tran
发明人： Thai Tran
IPC分类号： G01C21/30
CPC分类号： G01C21/3611
摘要： A method and apparatus allows a user to input a tentative destination which is proximate to an intended destination when the address data for the intended destination is not found in the map database. The method includes the steps of allowing a user to specifying an intended destination in the navigation system and searching address data for the intended destination, notifying the user that the address data is not found in the map database, selecting a method for inputting data indicating a tentative destination which is considered proximate to the intended destination, allowing the user to specify the tentative destination through the selected input method, and determining a location of the tentative destination and detecting address data indicating the location of the tentative destination.
摘要翻译：当在地图数据库中没有找到预期目的地的地址数据时，方法和装置允许用户输入接近预定目的地的暂定目的地。该方法包括以下步骤：允许用户在导航系统中指定预定的目的地并搜索预期目的地的地址数据，通知用户地图数据未在地图数据库中找到，选择用于输入指示认为接近预定目的地的暂定目的地，允许用户通过所选择的输入方法指定暂定目的地，以及确定暂定目的地的位置并检测指示暂定目的地的位置的地址数据。

17. 发明授权

US07639163B2 Method and apparatus for displaying route guidance list for navigation system 有权
标题翻译：显示导航系统路线指引清单的方法和装置
公开(公告)号：US07639163B2
公开(公告)日：2009-12-29
申请号：US11732545
申请日：2007-04-04
申请人： Thai Tran
发明人： Thai Tran
IPC分类号： G08G1/123
CPC分类号： G01C21/36
摘要： A method and apparatus for a navigation system displays a route guidance list that lists information on roads that intersect with a calculated route to the destination in an organized and simplified manner. The method includes the steps of calculating a route to a destination specified by a user, retrieving information on intersecting roads that intersect with the calculated route; and displaying a route guidance list which lists road names on which the calculated route is established and a distance associated with the intersecting road. The route guidance list shows one integrated road name if there are two or more identical road names consecutively on the calculated route and an overall distance of the identical road names that intersect with the calculated route.
摘要翻译：一种用于导航系统的方法和装置，以有组织和简化的方式显示路线指引列表，该路线指引列表将与计算出的路线相交的道路信息列入目的地。该方法包括以下步骤：计算由用户指定的目的地的路由，检索与所计算的路线相交的相交道路的信息; 并且显示列出建立了所计算的路线的道路名称和与相交道路相关联的距离的路线引导列表。如果在计算出的路线上连续地有两个或更多个相同的道路名称，并且与所计算的路线相交的相同道路名称的总距离，则路线指南列表显示一个综合道路名称。

18. 发明申请

US20080249709A1 Method and apparatus for inputting data indicating tentative destination for navigation system 有权
标题翻译：用于输入表示用于导航系统的暂定目的地的数据的方法和装置
公开(公告)号：US20080249709A1
公开(公告)日：2008-10-09
申请号：US11732564
申请日：2007-04-04
申请人： Thai Tran
发明人： Thai Tran
IPC分类号： G01C21/34
CPC分类号： G01C21/3611
摘要： A method and apparatus for inputting a tentative destination which is proximate to an intended destination when the address data for the intended destination is not found in the map database. The method includes the steps of allowing a user to specifying an intended destination in the navigation system and searching address data for the intended destination, notifying the user that the address data is not found in the map database, selecting a method for inputting data indicating a tentative destination which is considered proximate to the intended destination, allowing the user to specify the tentative destination through the selected input method, and determining a location of the tentative destination and detecting address data indicating the location of the tentative destination.
摘要翻译：当在地图数据库中没有找到预期目的地的地址数据时，输入临时目的地的方法和装置。该方法包括以下步骤：允许用户在导航系统中指定预定的目的地并搜索预期目的地的地址数据，通知用户地图数据未在地图数据库中找到，选择用于输入指示认为接近预定目的地的暂定目的地，允许用户通过所选择的输入方法指定暂定目的地，以及确定暂定目的地的位置并检测指示暂定目的地的位置的地址数据。

19. 发明授权

US07359893B2 Delivering items based on links to resources associated with search results 有权
标题翻译：根据与搜索结果相关联的资源链接提交项目
公开(公告)号：US07359893B2
公开(公告)日：2008-04-15
申请号：US10816460
申请日：2004-03-31
申请人： Pasha Sadri , Eckart Walther , Thai Tran
发明人： Pasha Sadri , Eckart Walther , Thai Tran
IPC分类号： G06F17/30
CPC分类号： G06F17/30861 , G06Q30/02 , Y10S707/99933 , Y10S707/99935
摘要： Techniques are described for delivering search results pages to the users of a search engine, where one or more search result listings on the search results pages include one or more items that are associated with links to resources that satisfy a related search and that satisfy a specified condition. The items that are delivered with the search results may be associated with a party that is different than the party that controls the resource to which the link is associated, and may be delivered such that any item that is displayed based on the item's association with a link to a resource is displayed in a frame of display that is different than a frame of the display in which the link to which the item is associated is displayed.
摘要翻译：描述了用于将搜索结果页面递送到搜索引擎的用户的技术，其中搜索结果页面上的一个或多个搜索结果列表包括与满足相关搜索的资源的链接相关联并满足指定的一个或多个项目的一个或多个项目条件。与搜索结果一起递送的项目可以与与控制链接所关联的资源的一方不同的一方相关联，并且可以被传送，使得基于该项目与一个链接到资源的显示器显示在不同于显示该项目的链接的显示器的帧的显示器框中。

20. 发明申请

US20160362472A1 CD20 THERAPIES, CD22 THERAPIES, AND COMBINATION THERAPIES WITH A CD19 CHIMERIC ANTIGEN RECEPTOR (CAR)- EXPRESSING CELL 审中-公开
标题翻译： CD20治疗方案，CD22治疗方案和与CD19基因抗体受体（CAR） - 表达细胞的联合治疗
公开(公告)号：US20160362472A1
公开(公告)日：2016-12-15
申请号：US15094674
申请日：2016-04-08
申请人： Hans Bitter , Jennifer Mary Bordeaux , Barbara Brannetti , Jennifer Brogdon , Naveen Kumar Dakappagari , Saar Gill , Steven Highfill , Lu Huang , Carl H. June , Ju Young Kim , Ming Lei , Na Li , Andreas Loew , Elena Orlando , Marco Ruella , Thai Tran , Jimin Zhang , Li Zhou
发明人： Hans Bitter , Jennifer Mary Bordeaux , Barbara Brannetti , Jennifer Brogdon , Naveen Kumar Dakappagari , Saar Gill , Steven Highfill , Lu Huang , Carl H. June , Ju Young Kim , Ming Lei , Na Li , Andreas Loew , Elena Orlando , Marco Ruella , Thai Tran , Jimin Zhang , Li Zhou
IPC分类号： C07K14/705 , A61K39/00
CPC分类号： C07K14/70596 , A61K38/00 , A61K39/0011 , A61K45/06 , A61K2039/5156 , A61K2039/5158 , A61K2039/70 , C07K14/7051 , C07K16/2803 , C07K16/2866 , C07K2317/24 , C07K2317/622 , C07K2319/00
摘要： The invention provides compositions and methods for treating diseases associated with expression of CD19, e.g., by administering a recombinant T cell comprising the CD19 CAR as described herein, in combination with one or more B-cell inhibitors, e.g., inhibitors of one or more of CD10, CD20, CD22, CD34, CD123, FLT-3, ROR1, CD79b, CD179b, or CD79a. The disclosure additionally features novel antigen binding domains and CAR molecules directed to CD20 and CD22, and uses, e.g., as monotherapies or in combination therapies. The invention also provides kits and compositions described herein.
摘要翻译：本发明提供了用于治疗与CD19表达相关的疾病的组合物和方法，例如通过与一种或多种B细胞抑制剂组合施用包含本文所述的CD19 CAR的重组T细胞，例如一种或多种 CD10，CD20，CD22，CD34，CD123，FLT-3，ROR1，CD79b，CD179b或CD79a。本公开另外具有指向CD20和CD22的新型抗原结合结构域和CAR分子，并且例如用作单一疗法或联合治疗。本发明还提供了本文所述的试剂盒和组合物。

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