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11. 发明申请

US20120307238A1 MICROSCOPE AND OBSERVATION METHOD 有权
标题翻译：显微镜和观察方法
公开(公告)号：US20120307238A1
公开(公告)日：2012-12-06
申请号：US13578164
申请日：2011-02-08
申请人： Katsumasa Fujita , Shogo Kawano , Masahito Yamanaka , Satoshi Kawata
发明人： Katsumasa Fujita , Shogo Kawano , Masahito Yamanaka , Satoshi Kawata
IPC分类号： G02B21/14 , G01J3/44 , G01N21/59 , G01N21/17 , G01N21/47 , G01J3/50
CPC分类号： G02B21/002 , G01N2021/653 , G01N2021/655 , G02B2207/114
摘要： Provided is a microscope and an observation method which can improve spatial resolution. A microscope according to an aspect of the invention includes a laser light source (10), an objective lens (16) that focuses light from the laser light source on a sample, and a detector (22) that detects the laser light as signal light from a sample (17) when the sample (17) is irradiated with the laser light. The light is applied to the sample with an intensity changed to obtain a nonlinear region where intensities of the light and the signal light have a nonlinear relation due to occurrence of saturation or nonlinear increase of the signal light when the light has a maximum intensity, and the detector (22) detects the signal light according to the intensity of the laser light to perform observation based on a saturation component or a nonlinear increase component of the signal light.
摘要翻译：提供了可以提高空间分辨率的显微镜和观察方法。根据本发明的一个方面的显微镜包括激光源（10），将来自激光光源的光聚焦在样本上的物镜（16）以及检测器（22），其将激光检测为信号光来自样品（17）当样品（17）被激光照射时。将光以强度变化的方式施加到样品，以获得非线性区域，其中当光具有最大强度时，光和信号光的强度由于饱和度的发生或信号光的非线性增加而具有非线性关系，以及检测器（22）根据激光的强度检测信号光，以基于信号光的饱和分量或非线性增加分量进行观察。

12. 发明申请

US20120107960A1 NONLINEAR LUMINESCENT MOLECULE, FLUORESCENT STAIN, AND OBSERVATION METHOD(AS AMENDED) 有权
标题翻译：非线性荧光分子，荧光染料和观察方法（如修改）
公开(公告)号：US20120107960A1
公开(公告)日：2012-05-03
申请号：US13380749
申请日：2010-06-21
申请人： Katsumasa Fujita , Shin Mizukami , Kazuya Kikuchi , Satoshi Kawata , Shogo Kawano
发明人： Katsumasa Fujita , Shin Mizukami , Kazuya Kikuchi , Satoshi Kawata , Shogo Kawano
IPC分类号： G01N21/64 , C09K11/06 , C09B51/00
CPC分类号： C07F5/022 , C09B23/04 , C09B57/10 , G01N21/6428 , G01N2021/6432 , G01N2021/6439 , G01N2021/6441
摘要： The present invention relates to a nonlinear fluorescent molecule that generates a nonlinear fluorescence reaction by incidence of excitation light. This nonlinear fluorescence molecule includes donors and, and an acceptor that is coupled to the donors and. As the donor is excited by the incidence of the excitation light, electric charge moves from the donor to the acceptor. Then, the donor and the acceptor form a charge separated state. In a state in which the charge separated state is maintained, the donor fluoresces when transiting from an excited state to a ground state.
摘要翻译：本发明涉及通过激发光的入射产生非线性荧光反应的非线性荧光分子。这种非线性荧光分子包括供体和与供体偶联的受体。当供体被激发光的发生激发时，电荷从供体移动到受体。然后，供体和受体形成电荷分离状态。在保持电荷分离状态的状态下，当从激发态转变为基态时，供体发荧光。

13. 发明申请

US20100232459A1 Pulse Laser Light Timing Adjusting Device, Adjusting Method, and Optical Microscope 审中-公开
标题翻译：脉冲激光定时调节装置，调节方法和光学显微镜
公开(公告)号：US20100232459A1
公开(公告)日：2010-09-16
申请号：US12227412
申请日：2006-11-20
申请人： Mamoru Hashimoto , Takeo Minamikawa , Naoki Tanimoto , Minoru Kobayashi , Katsumasa Fujita , Satoshi Kawata , Tsutomu Araki
发明人： Mamoru Hashimoto , Takeo Minamikawa , Naoki Tanimoto , Minoru Kobayashi , Katsumasa Fujita , Satoshi Kawata , Tsutomu Araki
IPC分类号： G02F1/35
CPC分类号： G01J3/44 , G01J3/10 , G01J11/00 , G01N2021/653 , H01S3/139 , H01S3/2383
摘要： To provide a pulse laser light timing adjusting device capable of easily adjusting pulse laser light timing, a timing adjusting method, and an optical microscope. An optical microscope in accordance with the present invention includes mirror pairs 21 and 31 to generates the first timing adjusting optical beam in which the first pulse laser light ω1 is delayed from the second pulse laser light ω2 and the second timing adjusting optical beam in which the second pulse laser light ω2 is delayed from the first pulse laser light having a first wavelength from the optical beam extracted at the beam samplers 15 and 16, a first detector 23 and a second detector 33 to output a first detection signal and a second detection signal based on a nonlinear optical effect, and timing adjusting means 42 to adjust the timing based on the first detection signal and the second detection signal.
摘要翻译：提供能够容易地调整脉冲激光定时的脉冲激光定时调整装置，定时调整方法和光学显微镜。根据本发明的光学显微镜包括镜对21和31，用于产生第一定时调整光束，其中第一脉冲激光光源ω1从第二脉冲激光光源ω2延迟，第二定时调整光束第二脉冲激光器ω2从具有第一波长的第一脉冲激光从在光束采样器15和16处提取的光束被延迟，第一检测器23和第二检测器33输出第一检测信号和第二检测信号以及基于第一检测信号和第二检测信号来调整定时的定时调整装置42。

14. 发明申请

US20080215272A1 Fluorescence Microscope and Fluorescence Microscope Method 有权
标题翻译：荧光显微镜和荧光显微镜法
公开(公告)号：US20080215272A1
公开(公告)日：2008-09-04
申请号：US11792304
申请日：2005-10-14
申请人： Katsumasa Fujita , Satoshi Kawata , Naoko Nakamura , Osamu Nakamura , Minoru Kobayashi
发明人： Katsumasa Fujita , Satoshi Kawata , Naoko Nakamura , Osamu Nakamura , Minoru Kobayashi
IPC分类号： G06F15/00
CPC分类号： G01N21/6458 , G01N21/6408 , G01N21/6428 , G01N2201/0697 , G02B21/16
摘要： To increase spatial resolution by observing a sample based on saturated fluorescence components. A fluorescence microscope according to the present invention includes: a laser light source 10 emitting laser light as excitation light; an objective lens 13 focusing the laser light and applying the focused laser light to a sample 14; a detector 22 detecting fluorescence generated in the sample 14 with the laser light; and a stage 15 scanning the sample 14 while moving the sample 14 relative to the laser light, wherein the laser light is applied to the sample with varying intensities such that saturation of fluorescence occurs at the maximum intensity of the laser light, and fluorescence is detected with the detector in accordance with intensity of the laser light, and the sample is observed based on the saturation components of fluorescence.
摘要翻译：通过观察基于饱和荧光成分的样品来增加空间分辨率。根据本发明的荧光显微镜包括：发射激光作为激发光的激光光源10; 聚焦激光并将聚焦的激光施加到样品14的物镜13; 用激光检测样品14中产生的荧光的检测器22; 以及在样品14相对于激光移动的同时扫描样品14的阶段15，其中激光以不同的强度施加到样品，使得在激光的最大强度下发生荧光饱和，并且检测到荧光与检测器根据激光的强度，并且基于荧光的饱和分量观察样品。

15. 发明授权

US07781711B2 Fluorescence microscope for which a sample is observed based on the saturation components of fluorescence and fluorescence microscopy method 有权
标题翻译：基于荧光和荧光显微镜法的饱和组分观察样品的荧光显微镜
公开(公告)号：US07781711B2
公开(公告)日：2010-08-24
申请号：US11792304
申请日：2005-10-14
申请人： Katsumasa Fujita , Satoshi Kawata , Osamu Nakamura , Naoko Nakamura, legal representative , Minoru Kobayashi
发明人： Katsumasa Fujita , Satoshi Kawata , Osamu Nakamura , Minoru Kobayashi
IPC分类号： G02B7/04
CPC分类号： G01N21/6458 , G01N21/6408 , G01N21/6428 , G01N2201/0697 , G02B21/16
摘要： To increase spatial resolution by observing a sample based on saturated fluorescence components. A fluorescence microscope according to the present invention includes: a laser light source 10 emitting laser light as excitation light; an objective lens 13 focusing the laser light and applying the focused laser light to a sample 14; a detector 22 detecting fluorescence generated in the sample 14 with the laser light; and a stage 15 scanning the sample 14 while moving the sample 14 relative to the laser light, wherein the laser light is applied to the sample with varying intensities such that saturation of fluorescence occurs at the maximum intensity of the laser light, and fluorescence is detected with the detector in accordance with intensity of the laser light, and the sample is observed based on the saturation components of fluorescence.
摘要翻译：通过观察基于饱和荧光成分的样品来增加空间分辨率。根据本发明的荧光显微镜包括：发射激光作为激发光的激光光源10; 聚焦激光并将聚焦的激光施加到样品14的物镜13; 用激光检测样品14中产生的荧光的检测器22; 以及在样品14相对于激光移动的同时扫描样品14的阶段15，其中激光以不同的强度施加到样品，使得在激光的最大强度下发生荧光饱和，并且检测到荧光与检测器根据激光的强度，并且基于荧光的饱和分量观察样品。

16. 发明申请

US20130044956A1 IMAGE PROCESSING APPARATUS AND METHOD 有权
标题翻译：图像处理装置和方法
公开(公告)号：US20130044956A1
公开(公告)日：2013-02-21
申请号：US13569551
申请日：2012-08-08
申请人： Satoshi Kawata , Takuma Yamamoto , Yasunori Taguchi , Nobuyuki Matsumoto
发明人： Satoshi Kawata , Takuma Yamamoto , Yasunori Taguchi , Nobuyuki Matsumoto
IPC分类号： G06K9/46
CPC分类号： G06T5/002 , G06K9/66 , G06T5/20 , H04N1/409
摘要： According to one embodiment, an image processing apparatus includes following units. The correlation calculation unit calculates correlations between a first region and predetermined first basis vectors. The distance calculation unit calculates distances between the first region and second regions on a subspace generated by the second basis vectors selected from the first basis vectors. The feature quantity calculation unit calculates a feature quantity based on the correlations. The weight calculation unit calculates weights based on the distances and the feature quantity. The pixel value calculation unit calculates a weighted average of pixel values according to the weights to generate an output pixel value.
摘要翻译：根据一个实施例，图像处理装置包括以下单元。相关计算单元计算第一区域和预定的第一基本向量之间的相关性。距离计算单元计算由从第一基本向量中选择的第二基本向量生成的子空间上的第一区域和第二区域之间的距离。特征量计算单元基于相关性来计算特征量。权重计算单元基于距离和特征量计算权重。像素值计算单元根据权重来计算像素值的加权平均值，以生成输出像素值。

17. 发明授权

US08372249B2 Photoreduction processing method of three-dimensional metal nanostructure 有权
标题翻译：三维金属纳米结构的光还原处理方法
公开(公告)号：US08372249B2
公开(公告)日：2013-02-12
申请号：US13413852
申请日：2012-03-07
申请人： Takuo Tanaka , Nobuyuki Takeyasu , Satoshi Kawata
发明人： Takuo Tanaka , Nobuyuki Takeyasu , Satoshi Kawata
IPC分类号： B01J19/12 , B22F9/18
CPC分类号： C30B29/02 , B22F1/0018 , B22F9/24 , B22F2999/00 , B82Y30/00 , C23C18/14 , C30B7/00 , C30B29/605 , B22F2202/11
摘要： In a method of producing a metal structure by photoreducing metal ion, a substance capable of suppressing growth of metal crystal is added to a medium in which metal ion is dispersed to prevent growth of the metal crystal produced by photoreduction of the metal ion, thereby processing resolution of a metal structure formed of the metal crystal is improved.
摘要翻译：在通过光还原金属离子制造金属结构体的方法中，将能够抑制金属结晶生长的物质添加到分散有金属离子的介质中，以防止金属离子光还原产生的金属晶体的生长，由此加工提高了由金属晶体形成的金属结构的分辨率。

18. 发明授权

US07619958B2 Pickup apparatus for multi-layer optical disc 失效
标题翻译：多层光盘拾取装置
公开(公告)号：US07619958B2
公开(公告)日：2009-11-17
申请号：US11672815
申请日：2007-02-08
申请人： Masahiko Ujiie , Takayuki Hayashi , Takuo Tanaka , Satoshi Kawata
发明人： Masahiko Ujiie , Takayuki Hayashi , Takuo Tanaka , Satoshi Kawata
IPC分类号： G11B7/00
CPC分类号： G11B7/139 , G11B2007/0013
摘要： An optical pickup apparatus comprises an orbicular zone forming lens group 14 for forming the section of the laser beam, which is irradiated to an optical disc DK having plural recording layers, into an annular shape, a condenser lens 35 that converges the reflected beam from the optical disc DK, and a pinhole plate 36 having formed thereto a pinhole 36a with a size corresponding to a flux diameter of the reflected beam converged by the condenser lens 35. The orbicular zone forming lens group 14 refracts the laser beam irradiated to the optical disc DK so as to form the section of the laser beam into an annular shape in order that the internal diameter of the annular converged flux formed on the pinhole plate 36a by the reflected beam from the recording layers other than the recording layer having an optical spot formed thereon becomes greater than the diameter of the pinhole 36a.
摘要翻译：一种光学拾取装置，包括形成透镜组14的环形区域，用于将激光束的被照射到具有多个记录层的光盘DK的部分形成为环形，聚光透镜35使来自光盘DK和针孔板36，其具有针孔36a，针孔36a的尺寸对应于由聚光透镜35会聚的反射光束的通量直径。圆形区域形成透镜组14折射照射到光盘的激光束 DK，以便将激光束的截面形成为环形，以便通过形成在具有光点的记录层以外的记录层的反射光束形成在针孔板36a上的环形会聚通量的内径其上变得大于针孔36a的直径。

19. 发明授权

US07532397B2 Optical material, optical device fabricated therefrom, and method for fabricating the same 失效
标题翻译：光学材料，由其制造的光学器件及其制造方法
公开(公告)号：US07532397B2
公开(公告)日：2009-05-12
申请号：US11455092
申请日：2006-06-19
申请人： Takuo Tanaka , Satoshi Kawata
发明人： Takuo Tanaka , Satoshi Kawata
IPC分类号： G02B5/30
CPC分类号： G02F1/0136 , B82Y20/00 , G02B5/3066 , G02F2202/30 , Y10S977/834
摘要： In order to make a reflection coefficient in boundary surface between materials to be zero and permeate 100% of a light independent of a polarization direction, an optical device made of an optical material composed of a metamaterial prepared by arranging a plurality of at least either of electrical resonators or magnetic resonators each being smaller than a wavelength of a light wave in only a predetermined plane, and at least either of the electrical resonators and the magnetic resonators arranged functioning with respect to s-polarization, wherein at least either of the dielectric constant or the magnetic permeability is controlled in response to the function to induce a Brewster phenomenon in the s-polarization.
摘要翻译：为了使材料之间的边界面中的反射系数为零，并且透过与偏振方向无关的100％的光，由光学材料制成的光学装置由通过将多个至少一个电谐振器或磁谐振器各自小于仅在预定平面中的光波的波长，并且电谐振器和磁谐振器中的至少一个相对于s极化排列起作用，其中介电常数或者响应于在s极化中引起布鲁斯特现象的功能来控制磁导率。

20. 发明申请

US20090067028A1 OPTICAL NEAR-FIELD DISTRIBUTION TRANSFER DEVICE 有权
标题翻译：光学近场分布传输设备
公开(公告)号：US20090067028A1
公开(公告)日：2009-03-12
申请号：US12097999
申请日：2006-12-19
申请人： Satoshi Kawata , Jun-ichi Kato , Atsushi Ono
发明人： Satoshi Kawata , Jun-ichi Kato , Atsushi Ono
IPC分类号： G02F1/01
CPC分类号： G02B6/1226 , G01Q60/22 , G02B5/008
摘要： Long-distance transfer of a super-resolution near field can be performed with a wavelength condition of high degree of freedom. Not only an image in same size can be merely transferred, but also a magnified image can be transferred. Thus the processing technique of a near-field image is improved. Small rods are erected at predetermined spacing with one another on a two-dimensional plane. At least the exterior surface of each small rod is made of a predetermined material having a dielectric constant ∈m meeting the condition “∈m≦−∈d” where ∈d is the dielectric constant of the surrounding medium. The axes of the small rods can be extended to a predetermined direction with respect to the two-dimensional plane. An optical near-field is incidented to one end of each small rod.
摘要翻译：能够以高自由度的波长条件进行超分辨率近场的长距离传送。不仅可以转移相同尺寸的图像，还可以转移放大图像。因此，近场图像的处理技术得到改善。在二维平面上以预定间隔彼此竖立小杆。每个小杆的至少外表面由具有介电常数∈m的预定材料制成，满足条件“∈m<= - ∈d”，其中∈d是周围介质的介电常数。小杆的轴线可以相对于二维平面延伸到预定方向。光学近场被入射到每个小杆的一端。

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