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11. 发明授权

US5310873A Cyclohexapeptide compound 失效
标题翻译：环六肽化合物
公开(公告)号：US5310873A
公开(公告)日：1994-05-10
申请号：US492001
申请日：1990-03-12
申请人： Dennis M. Schmatz , Jan S. Tkacz , Robert E. Schwartz , Mervyn Turner
发明人： Dennis M. Schmatz , Jan S. Tkacz , Robert E. Schwartz , Mervyn Turner
IPC分类号： A61K38/00 , A61P31/10 , A61P35/00 , C07K1/113 , C07K7/56 , C07K14/195 , C07K14/41 , C12N9/80 , C12P21/02 , C12P21/04 , C12R1/01 , C12R1/38 , A61K37/02 , C07K5/12 , C07K7/06
CPC分类号： C07K7/56
摘要： A cyclohexapeptide base which is the nucleus of closely related antibiotics obtained by culturing Zalerion arboricola and its salts are described. They are useful intermediates for the preparation of new semisynthetic compounds having antimicrobial activity.
摘要翻译：描述了通过培养Zalerion arboricola及其盐获得的紧密相关抗生素核的环己肽基。它们是制备具有抗微生物活性的新的半合成化合物的有用中间体。

12. 发明授权

US5194377A Antibiotic agent 失效
标题翻译：抗生素
公开(公告)号：US5194377A
公开(公告)日：1993-03-16
申请号：US742968
申请日：1991-08-09
申请人： Robert E. Schwartz , Raymond F. White
发明人： Robert E. Schwartz , Raymond F. White
IPC分类号： A61K38/00 , C07K7/56 , C12P21/04
CPC分类号： C07K7/56 , A61K38/00 , Y10S435/911
摘要： An antibiotic agent produced by the cultivation of Zalerion arboricola which is a cyclic lipopeptide with very high activity against human pathogens and of very low mammalian toxicity is described. Its production and isolation are also described.
摘要翻译：描述了通过培养作为对人类病原体具有非常高的活性且具有非常低的哺乳动物毒性的环状脂肽的Zalerion arboricola产生的抗生素。还描述了其生产和分离。

13. 发明授权

US5386009A Lipopeptide derivatives 失效
公开(公告)号：US5386009A
公开(公告)日：1995-01-31
申请号：US495200
申请日：1990-03-19
申请人： Milton L. Hammond , Robert E. Schwartz , James M. Balkovec
发明人： Milton L. Hammond , Robert E. Schwartz , James M. Balkovec
IPC分类号： A61K38/00 , C07K7/56 , A61K37/02 , C07K5/12 , C07K7/06
CPC分类号： C07K7/56 , A61K38/00
摘要： The present invention is directed to water-soluble derivatives of antibiotic lipopeptides. The derivatives have good solubility properties in aqueous medium, rendering them more useful as therapeutic agents.

14. 发明授权

US5385884A Lipopeptide derivatives 失效
标题翻译：脂肽衍生物
公开(公告)号：US5385884A
公开(公告)日：1995-01-31
申请号：US750380
申请日：1991-08-27
申请人： Milton L. Hammond , Robert E. Schwartz , James M. Balkovec
发明人： Milton L. Hammond , Robert E. Schwartz , James M. Balkovec
IPC分类号： A61K38/00 , C07K7/56 , C07K5/12 , C07K7/06 , A61K37/02
CPC分类号： C07K7/56 , A61K38/00
摘要： There are disclosed lipopeptide derviatives of the general formula: ##STR1## where the substituents are defined herein which have antifungal and antiprotozoal activity. There are also disclosed pharmaceutical compositions containing these compounds.
摘要翻译：已经公开了以下通式的脂肽衍生物：其中本文定义的取代基具有抗真菌和抗原虫活性的（A）。还公开了含有这些化合物的药物组合物。

15. 发明授权

US5200079A Circular clarifier including improved skimmer clarifier 失效
标题翻译：圆形澄清器，包括改进的撇渣器澄清器
公开(公告)号：US5200079A
公开(公告)日：1993-04-06
申请号：US540835
申请日：1990-06-20
申请人： Robert E. Schwartz , Donald C. Vock
发明人： Robert E. Schwartz , Donald C. Vock
IPC分类号： B01D21/06 , B01D21/24
CPC分类号： B01D21/2433 , B01D21/06 , B01D21/2427 , B01D21/307
摘要： A circular clarifier includes a skimmer assembly mounted on a rotatable arm of the clarifier. The skimmer assembly includes a parallelogram linkage having a pair of end links pivotably connected between upper and lower intermediate links. The skimmer blade is mounted to one of the end links to skim the liquid containing volume of the clarifier. The parallelogram linkage is mounted to the rotating arm by a support assembly at upper and lower pivot connections. These pivot connections are positioned at central portions of the respective intermediate links such that both of the intermediate links extend outwardly on both sides of the respective pivot connection. Either a counterweight or a floatation element is mounted to the parallelogram linkage to bias the linkage for rotation about the pivot connections to position the skimmer blade in an upper position.
摘要翻译：圆形澄清器包括安装在澄清器的可旋转臂上的撇渣器组件。撇渣器组件包括平行四边形连杆机构，其具有可枢转地连接在上部和下部中间连杆之间的一对端部连杆。撇渣器叶片安装到一个端部连接件上，以清除澄清池的容纳液体的容积。平行四边形连杆通过上部和下部枢轴连接处的支撑组件安装到旋转臂。这些枢转连接件位于相应的中间连杆的中心部分处，使得两个中间连接件在相应的枢轴连接的两侧向外延伸。配重或浮动元件安装到平行四边形连杆机构以偏置连杆机构以围绕枢转连接件旋转以将撇渣器刀片定位在上部位置。

16. 发明授权

US4798150A Apparatus for handling ash 失效
标题翻译：灰处理装置
公开(公告)号：US4798150A
公开(公告)日：1989-01-17
申请号：US125249
申请日：1987-11-25
申请人： Dale W. Pressnall , Michael R. Keller , Robert E. Schwartz
发明人： Dale W. Pressnall , Michael R. Keller , Robert E. Schwartz
IPC分类号： F23J1/02
CPC分类号： F23J1/02
摘要： Apparatus for handling ash. A tank is filled with water and has the lower end thereof located at a substantial angle from horizontal. The tank is positioned beneath an incinerator to receive ash therefrom. An ash wheel having sectors defined by upright paddle elements has a portion thereof received beneath the water into which the ash falls and a portion thereof which extends over one edge of the tank. As the wheel rotates, ash is swept over the edge of the tank and onto a conveyor for disposal.
摘要翻译：灰处理装置水箱充满水并且其下端位于与水平方向大致的角度。油箱位于焚化炉下方以接收灰分。具有由直立叶片元件限定的扇区的灰轮具有容纳在水下的部分，灰分落入其中，并且其部分在罐的一个边缘上延伸。当车轮旋转时，灰尘被扫过罐的边缘并传送到传送带上以便处理。

17. 发明授权

US4457696A Large capacity air-powered smokeless flare 失效
标题翻译：大容量空中无烟火炬
公开(公告)号：US4457696A
公开(公告)日：1984-07-03
申请号：US300175
申请日：1981-09-08
申请人： Robert E. Schwartz , Roger K. Noble , Michael R. Keller
发明人： Robert E. Schwartz , Roger K. Noble , Michael R. Keller
IPC分类号： F23G7/08 , F23D13/20
CPC分类号： F23G7/08
摘要： A large capacity air-powered flare for smokeless combustion of very large volumes of vented waste gases, comprises a first inner vertical conduit of diameter D1, for the flow of waste gas, and a second larger coaxial conduit of diameter D2, for the flow of primary combustion air, at a selected velocity in the annular space therebetween. Above the top the inner conduit there is a cylindrical obstruction of diameter D3 which is greater than D1, but less than D2. This forces the upwardly flowing gases to be deflected outwardly and upwardly into the second annular space between the obstruction and the outer conduit. The velocity of primary combustion air in the second annular space is at least 50 f.p.s., which serves to thoroughly mix with the inflowing gases so that as they rise through the second annular space they continue flowing above the top of the flare as an annular wall of high velocity gas, air and flame. This high velocity annular flow has large surface area on the outside and inside. Because of the high velocity of flow, secondary air is induced into the outside wall of this column, and also axially downwardly into the interior of this flow, where it moves radially outwardly to intersect the flowing gas and provide additional combustion air.
摘要翻译：用于非常大量排放的废气的无烟燃烧的大容量空气动力火炬包括用于废气流的直径为D1的第一内垂直导管和直径为D2的第二较大同轴导管，初级燃烧空气以选定的速度在它们之间的环形空间中。在顶部上方，内部管道具有直径D3的圆柱形阻塞物，其大于D1，但小于D2。这迫使向上流动的气体向外和向上偏转到阻塞物和外导管之间的第二环形空间中。初级燃烧空气在第二环形空间中的速度为至少50fps，其用于与流入的气体充分混合，使得当它们通过第二环形空间上升时，它们继续流过火炬顶部的上方作为环形壁高速气体，空气和火焰。这种高速环形流动在外部和内部具有大的表面积。由于流速高，二次空气被引入该塔的外壁，并且也轴向向下进入该流动的内部，其中径向向外移动以与流动的气体相交并提供额外的燃烧空气。

18. 发明授权

US3982881A Invisible flare burner 失效
标题翻译：隐形火炬燃烧器
公开(公告)号：US3982881A
公开(公告)日：1976-09-28
申请号：US546210
申请日：1975-02-03
申请人： Robert E. Schwartz , Roger K. Noble
发明人： Robert E. Schwartz , Roger K. Noble
IPC分类号： F23G7/08 , F23D13/20
CPC分类号： F23G7/08 , F23G7/085
摘要： An improved low pollution invisible flare burner comprises a tall stack lined with ceramic. The stack is supported above the ground level and has a wind screen surrounding the open portion below the stack floor. Primary air is introduced under pressure in a tube below and coaxial with the stack. The top of the tube contains a burner for the vented hydrocarbon gases. The top of the tube and the burner are at the level of the floor of the stack. Secondary air is introduced into the stack in the annular space between the primary air conduit and an opening in the floor of the stack. Turbulent mixing of the primary air and the vent gas, plus the availability of sufficient atmospheric air for complete combustion, plus the effect of heated ceramic in the vicinity of the flame, provide means for complete combustion of the vented gases with low emission of smoke and light.
摘要翻译：改进的低污染隐形火炬燃烧器包括一个内衬陶瓷的高堆叠。堆叠被支撑在地面上方，并且具有围绕堆叠地板下方的开口部分的风屏。一次空气在压力下被引入到下面的管中并且与堆叠同轴。管的顶部包含用于排出的烃气体的燃烧器。管和燃烧器的顶部位于堆叠的地板的高度。二次空气被引入堆叠中的主空气导管和堆叠底板的开口之间的环形空间中。初级空气和排放气体的紊流混合，以及足够的大气空气用于完全燃烧，以及加热陶瓷在火焰附近的影响，提供了用于完全燃烧具有低排放烟雾的排出气体的装置，以及光。

19. 发明授权

US06468314B2 Cartilage repair unit 有权
标题翻译：软骨修复单位
公开(公告)号：US06468314B2
公开(公告)日：2002-10-22
申请号：US09801450
申请日：2001-03-08
申请人： Robert E. Schwartz , Daniel A. Grande
发明人： Robert E. Schwartz , Daniel A. Grande
IPC分类号： A61F202
CPC分类号： A61B17/064 , A61B17/0642 , A61B17/0643 , A61B17/58 , A61B2017/00004 , A61B2017/0646 , A61B2017/0647 , A61F2/30749 , A61F2/30756 , A61F2/3094 , A61F2/30965 , A61F2/38 , A61F2002/2817 , A61F2002/30013 , A61F2002/30062 , A61F2002/30064 , A61F2002/30113 , A61F2002/30123 , A61F2002/30125 , A61F2002/3013 , A61F2002/30143 , A61F2002/30146 , A61F2002/30153 , A61F2002/30156 , A61F2002/30159 , A61F2002/30171 , A61F2002/30291 , A61F2002/30299 , A61F2002/30306 , A61F2002/30354 , A61F2002/30382 , A61F2002/30405 , A61F2002/30451 , A61F2002/30456 , A61F2002/30457 , A61F2002/30477 , A61F2002/30484 , A61F2002/30492 , A61F2002/30495 , A61F2002/305 , A61F2002/30502 , A61F2002/30565 , A61F2002/30579 , A61F2002/30593 , A61F2002/30594 , A61F2002/30598 , A61F2002/30604 , A61F2002/30611 , A61F2002/30751 , A61F2002/30761 , A61F2002/30777 , A61F2002/30785 , A61F2002/30841 , A61F2002/30878 , A61F2002/30879 , A61F2002/30881 , A61F2002/30891 , A61F2002/30892 , A61F2002/30904 , A61F2002/30952 , A61F2002/30971 , A61F2210/0004 , A61F2220/0025 , A61F2220/0033 , A61F2220/0058 , A61F2230/0006 , A61F2230/0008 , A61F2230/001 , A61F2230/0017 , A61F2230/0019 , A61F2230/0023 , A61F2230/0028 , A61F2230/005 , A61F2230/0091 , A61F2230/0093 , A61F2230/0097 , A61F2240/001 , A61F2250/0024 , A61F2250/0063 , A61F2310/00365
摘要： A bio-absorbable cartilage repair system is provided for regenerating damaged or destroyed articular cartilage on a joint surface of a bone by establishing a chondrogenic growth-supporting matrix between an area of damaged or destroyed articular cartilage that has been removed and an adjacent healthy area of articular cartilage and subchondral cancellous bone. The system is an assembly of a delivery unit and a porous insert. The delivery unit is formed of bio-absorbable material and configured and dimensioned to be mounted in both an area of damaged or destroyed articular cartilage that has been removed and an adjacent healthy area of articular cartilage and cancellous bone. The delivery unit has a central body and a plurality of radially extending, flexible support arms projecting outwardly from the central body and configured and dimensioned to support the insert at least partially thereover. The insert is supported by the delivery unit, formed of bio-absorbable material, and establishes communication between the removed area and the adjacent healthy area for a chondrogenic growth-supporting matrix.
摘要翻译：提供生物可吸收的软骨修复系统，用于通过在被去除的损伤或破坏的关节软骨的区域和相邻的健康区域之间建立软骨形成生长支持基质来再生骨骼的关节表面上的损伤或破坏的关节软骨关节软骨和软骨下松质骨。该系统是输送单元和多孔插入件的组件。递送单元由生物吸收材料形成，并且构造和尺寸被安装在被去除的损伤或破坏的关节软骨的区域中，以及相关的关节软骨和松质骨的健康区域。输送单元具有中心体和从中心体向外突出的多个径向延伸的柔性支撑臂，并且构造和尺寸设计成至少部分地支撑插入件。插入物由可生物吸收材料形成的递送单元支撑，并且在去除区域和相邻健康区域之间建立连接，用于软骨形成生长支持基质。

20. 发明授权

US06436395B1 Rosellinia subiculata ATCC 74386 and fungus ATCC 74387 for producing sordarin compounds for fungi control 失效
标题翻译： Rosellinia subiculata ATCC 74386和真菌ATCC 74387，用于生产用于真菌控制的sordarin化合物
公开(公告)号：US06436395B1
公开(公告)日：2002-08-20
申请号：US09269004
申请日：1999-06-23
申请人： Gerald F. Bills , Anne W. Dombrowski , Wendy S. Horn , Richard K. Jansson , Mark Rattray , Dennis Schmatz , Robert E. Schwartz
发明人： Gerald F. Bills , Anne W. Dombrowski , Wendy S. Horn , Richard K. Jansson , Mark Rattray , Dennis Schmatz , Robert E. Schwartz
IPC分类号： A01N6300
CPC分类号： C07H15/18 , A01N45/00 , A01N63/04 , C12N1/14 , C12P17/06 , C12P17/185 , C12P19/56 , Y10S435/911
摘要： Disclosed is a method for controlling phytopathogenic fungi using pure strains of Rosellinia subiculata ATCC 74386 and fungus ATCC 74387. Further, methods of producing a sordarin compound are disclosed. The method includes cultivating each strain separately in a nutrient medium containing assimilable sources of carbon and nitrogen and recovering the compound. A sordarin compound of formula I is also disclosed. Also an antifungal composition containing a sordarin compound is also disclosed.
摘要翻译：公开了一种使用纯化的Rosellinia subiculata ATCC 74386和真菌ATCC 74387的菌株来控制植物病原真菌的方法。此外，公开了生产桑德林化合物的方法。该方法包括在含有可同化碳源和氮源的营养培养基中分别培养各菌株并回收该化合物。还公开了式I的索尔定化合物。还公开了含有索尔纳林化合物的抗真菌组合物。

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