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11. 发明授权

US09014448B2 Associating acquired images with objects 有权
标题翻译：将获取的图像与对象相关联
公开(公告)号：US09014448B2
公开(公告)日：2015-04-21
申请号：US13516576
申请日：2010-11-24
申请人： Thomas Buelow , Kirsten Meetz , Martin Bergtholdt , Johannes Buurman , Axel Saalbach
发明人： Thomas Buelow , Kirsten Meetz , Martin Bergtholdt , Johannes Buurman , Axel Saalbach
IPC分类号： G06K9/00 , G06F19/00
CPC分类号： G06F19/321 , G06F19/00 , G16H30/20
摘要： A system for associating acquired images with objects is disclosed. It comprises an image selector (1) for selecting a stored image from a database (5) comprising a plurality of stored images, the database (5) comprising an association (21) between the stored image (6) and an object of interest; an image scanner (2) for acquiring a new image (9) comprising a representation (10) of at least part of the object of interest, during an imaging session; a user interface (3) for enabling a user, during the imaging session, to indicate that the new image (9) is to be associated with the object of interest; and an associating subsystem (4) for creating an association (23) between the new image (9) and the object of interest in the database. The user interface (3) is arranged for enabling a user to select the object of interest from a plurality of objects of interest associated with the stored image (6).
摘要翻译：公开了一种用于将获取的图像与对象相关联的系统。它包括用于从包括多个存储的图像的数据库（5）中选择存储的图像的图像选择器（1），所述数据库（5）包括存储的图像（6）和感兴趣对象之间的关联（21）用于在成像会话期间获取包括所述感兴趣对象的至少一部分的表示（10）的新图像（9）的图像扫描仪（2）用于在成像会话期间使用户能够指示新图像（9）与感兴趣对象相关联的用户界面（3）以及用于在新图像（9）和数据库中的感兴趣对象之间创建关联（23）的关联子系统（4）。用户界面（3）被布置为使得用户能够从与所存储的图像（6）相关联的多个感兴趣对象中选择感兴趣的对象。

12. 发明授权

US08145012B2 Device and process for multimodal registration of images 有权
标题翻译：图像多模式注册的设备和过程
公开(公告)号：US08145012B2
公开(公告)日：2012-03-27
申请号：US10598005
申请日：2005-02-04
申请人： Kirsten Meetz , Heinrich Schulz , Jens Berg , Joerg Sabczynski
发明人： Kirsten Meetz , Heinrich Schulz , Jens Berg , Joerg Sabczynski
IPC分类号： G06K9/32 , G06K9/00 , G06K9/40 , G06K9/20 , A61B5/05
CPC分类号： G06T3/4061 , G06T7/30 , G06T2207/10072 , G06T2207/10116 , G06T2207/10132 , G06T2207/30016 , Y10S128/922
摘要： The invention relates to a device and a process, with which images of different imaging methods can be registered, for example preoperatively obtained 3D X-ray images (A) and intra operatively obtained ultrasound images (B). First transformed images (A′,B′) are then generated in a data processing device (10), which are aligned to each other with regard to the peculiarities of each imaging method. Particularly from the three dimensional CT-image (A), can be generated a two dimensional image (A′) which adheres to the characteristic means of representation of an ultrasound system, while shaded areas behind bones and/or gas-filled volumes can be blended out. With a feature-based registration of the transformed images (A′, B′) errors are avoided, which are traced back to artifacts and peculiarities of the respective imaging methods.
摘要翻译：本发明涉及可以登记不同成像方法的图像的装置和方法，例如，术前获得的3D X射线图像（A）和经操作获得的超声图像（B）。然后，在数据处理装置（10）中生成第一变换图像（A'，B'），这些数据处理装置相对于每个成像方法的特性彼此对准。特别是从三维CT图像（A）可以产生一个二维图像（A'），它粘附在超声系统的表征的特征上，而在骨骼和/或充气体积之后的阴影区可以是混合了通过改变的图像（A'，B'）的基于特征的注册，避免了错误，这些错误被追溯到各个成像方法的伪影和特征。

13. 发明申请

US20130064437A1 HANDLING A SPECIMEN IMAGE 审中-公开
标题翻译：处理样本图像
公开(公告)号：US20130064437A1
公开(公告)日：2013-03-14
申请号：US13698905
申请日：2011-05-16
申请人： Kirsten Meetz , Thomas Buelow , Ingwer Curt Carlsen , Martin Bergtholdt
发明人： Kirsten Meetz , Thomas Buelow , Ingwer Curt Carlsen , Martin Bergtholdt
IPC分类号： G06K9/46
CPC分类号： G06T7/33 , G06T2207/10081 , G06T2207/10088 , G06T2207/10116 , G06T2207/10132 , G06T2207/10136 , G06T2207/30004 , G06T2207/30068 , G06T2207/30096
摘要： A system for handling a specimen image is disclosed. An image input (1) is configured to receive a body image representing at least a portion of a living body and a specimen image representing a dissected portion of the living body. An alignment unit (2) is configured to compute an alignment of the specimen image with the body image, based on image content of the specimen image and/or the body image. A border detector (3) is operatively connected to the alignment unit (2) and configured to detect at least part of an outer border of the dissected portion in the specimen image.
摘要翻译：公开了一种处理标本图像的系统。图像输入（1）被配置为接收表示生物体的至少一部分的身体图像和表示生物体的解剖部分的标本图像。对准单元（2）被配置为基于标本图像和/或身体图像的图像内容来计算样本图像与身体图像的对准。边界检测器（3）可操作地连接到对准单元（2）并且被配置为检测样本图像中的解剖部分的外部边界的至少一部分。

14. 发明申请

US20120243765A1 ASSOCIATING ACQUIRED IMAGES WITH OBJECTS 有权
标题翻译：与对象相关的获取图像
公开(公告)号：US20120243765A1
公开(公告)日：2012-09-27
申请号：US13516576
申请日：2010-11-24
申请人： Thomas Buelow , Kirsten Meetz , Martin Bergtholdt , Johannes Buurman , Axel Saalbach
发明人： Thomas Buelow , Kirsten Meetz , Martin Bergtholdt , Johannes Buurman , Axel Saalbach
IPC分类号： G06K9/00
CPC分类号： G06F19/321 , G06F19/00 , G16H30/20
摘要： A system for associating acquired images with objects is disclosed. It comprises an image selector (1) for selecting a stored image from a database (5) comprising a plurality of stored images, the database (5) comprising an association (21) between the stored image (6) and an object of interest; an image scanner (2) for acquiring a new image (9) comprising a representation (10) of at least part of the object of interest, during an imaging session; a user interface (3) for enabling a user, during the imaging session, to indicate that the new image (9) is to be associated with the object of interest; and an associating subsystem (4) for creating an association (23) between the new image (9) and the object of interest in the database. The user interface (3) is arranged for enabling a user to select the object of interest from a plurality of objects of interest associated with the stored image (6).
摘要翻译：公开了一种用于将获取的图像与对象相关联的系统。它包括用于从包括多个存储的图像的数据库（5）中选择存储的图像的图像选择器（1），所述数据库（5）包括存储的图像（6）和感兴趣对象之间的关联（21）用于在成像会话期间获取包括所述感兴趣对象的至少一部分的表示（10）的新图像（9）的图像扫描器（2）用于在成像会话期间使用户能够指示新图像（9）与感兴趣对象相关联的用户界面（3）以及用于在新图像（9）和数据库中的感兴趣对象之间创建关联（23）的关联子系统（4）。用户界面（3）被布置为使得用户能够从与所存储的图像（6）相关联的多个感兴趣对象中选择感兴趣的对象。

15. 发明授权

US09159127B2 Detecting haemorrhagic stroke in CT image data 有权
标题翻译：检测CT图像数据中的出血性中风
公开(公告)号：US09159127B2
公开(公告)日：2015-10-13
申请号：US12665422
申请日：2008-06-17
申请人： Kirsten Meetz , Thomas Buelow , Stewart Young
发明人： Kirsten Meetz , Thomas Buelow , Stewart Young
IPC分类号： G06T7/00 , A61B6/00 , G06T7/40
CPC分类号： G06T7/0012 , A61B6/032 , A61B6/12 , A61B6/501 , A61B2576/026 , G06T7/44 , G06T2207/10081 , G06T2207/20156 , G06T2207/30016 , G06T2207/30096 , G06T2210/41
摘要： The invention relates to a system (100) arranged to delineate the acute intracerebral haematoma in non-contrasted CT images in two stages. The first stage, performed by the extraction unit (110), employs an analysis of gray values of the image data in order to extract the candidate region. The candidate region may comprise both an acute haematoma and other regions having similar gray values, e.g., regions resulting from partial volume effects at the interface of the bony structures of the skull and the brain. The novel second stage, performed by the classification unit (120), analyzes spatial features of the candidate region such as, for example, the size, shape, and connectedness to the skull bone of the candidate region. Using spatial features of the candidate region improves the correctness of classification of the candidate region as a true or false acute haematoma.
摘要翻译：本发明涉及一种系统（100），其被布置成在两个阶段中描绘非对照CT图像中的急性脑内血肿。由提取单元（110）执行的第一阶段对图像数据的灰度值进行分析，以提取候选区域。候选区域可以包括急性血肿和具有相似灰度值的其它区域，例如由头骨和脑的骨骼结构的界面处的部分体积效应产生的区域。由分类单元（120）执行的新颖的第二阶段分析候选区域的空间特征，例如与候选区域的颅骨的尺寸，形状和连接性。使用候选区域的空间特征将候选区域的分类的正确性提高为真的或假的急性血肿。

16. 发明申请

US20100183211A1 DETECTING HAEMORRHAGIC STROKE IN CT IMAGE DATA 有权
标题翻译：检测CT图像数据中的血流动力学
公开(公告)号：US20100183211A1
公开(公告)日：2010-07-22
申请号：US12665422
申请日：2008-06-17
申请人： Kirsten Meetz , Thomas Buelow , Stewart Young
发明人： Kirsten Meetz , Thomas Buelow , Stewart Young
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , A61B6/032 , A61B6/12 , A61B6/501 , A61B2576/026 , G06T7/44 , G06T2207/10081 , G06T2207/20156 , G06T2207/30016 , G06T2207/30096 , G06T2210/41
摘要： The invention relates to a system (100) arranged to delineate the acute intracerebral haematoma in non-contrasted CT images in two stages. The first stage, performed by the extraction unit (110), employs an analysis of gray values of the image data in order to extract the candidate region. The candidate region may comprise both an acute haematoma and other regions having similar gray values, e.g., regions resulting from partial volume effects at the interface of the bony structures of the skull and the brain. The novel second stage, performed by the classification unit (120), analyzes spatial features of the candidate region such as, for example, the size, shape, and connectedness to the skull bone of the candidate region. Using spatial features of the candidate region improves the correctness of classification of the candidate region as a true or false acute haematoma.
摘要翻译：本发明涉及一种系统（100），其被布置成在两个阶段中描绘非对照CT图像中的急性脑内血肿。由提取单元（110）执行的第一阶段对图像数据的灰度值进行分析，以提取候选区域。候选区域可以包括急性血肿和具有相似灰度值的其它区域，例如由头骨和脑的骨骼结构的界面处的部分体积效应产生的区域。由分类单元（120）执行的新颖的第二阶段分析候选区域的空间特征，例如与候选区域的颅骨的尺寸，形状和连接性。使用候选区域的空间特征将候选区域的分类的正确性提高为真的或假的急性血肿。

17. 发明授权

US09600883B2 Plausible reference curves for dynamic, contrast-enhanced imaging studies 有权
公开(公告)号：US09600883B2
公开(公告)日：2017-03-21
申请号：US13262836
申请日：2010-03-09
申请人： Ingwer C. Carlsen , Kirsten Meetz , Joerg Bredno , Mark Olszewski
发明人： Ingwer C. Carlsen , Kirsten Meetz , Joerg Bredno , Mark Olszewski
IPC分类号： G06K9/00 , G06T7/00 , G01R33/563 , G01R33/56 , A61B6/00
CPC分类号： G06T7/0016 , A61B6/507 , G01R33/5601 , G01R33/56366 , G06T2207/10081 , G06T2207/10088 , G06T2207/10104 , G06T2207/10108 , G06T2207/20108 , G06T2207/30016 , G06T2207/30104
摘要： A comprehensive strategy is used to determine valid reference time-concentration curves (TCCs) from image data. The image data corresponds to a series of image scans acquired over time for an area of interest of a patient to which a contrast agent was previously administered. The image scans are initially registered to a common coordinate system. Then, observed potential reference TCCs in the image scans are compared to modeled reference TCCs to determine if the potential reference TCCs are plausible reference TCCs. Thereafter, any plausible reference TCCs are evaluated to determine if they contain residual, isolated motion artifacts. If a plausible reference TCC does not include any motion artifacts, the plausible reference TCC is considered a valid reference TCC. If a plausible reference TCC is determined to include motion artifacts, the plausible reference TCC is modified to a valid reference TCC by removing the motion artifacts, or otherwise the plausible reference TCC is rejected. The valid reference TCCs can be used to improve the effectiveness of dynamic, contrast-enhanced imaging studies.

18. 发明授权

US09757083B2 Scanning method and system 有权
公开(公告)号：US09757083B2
公开(公告)日：2017-09-12
申请号：US12809080
申请日：2008-12-26
申请人： Kirsten Meetz , Ingwer Curt Carlsen
发明人： Kirsten Meetz , Ingwer Curt Carlsen
IPC分类号： A61B6/00
CPC分类号： A61B6/504 , A61B6/501
摘要： To improve the scanning effect, a scanning method is provided, which comprises the steps of performing at least one of an nCT scan and a CTA scan on an object so as to obtain a set of images; detecting characteristics of a region of interest based on the set of images; and performing a CTP scan on the region of interest by adopting the characteristics to obtain a CTP image. By deriving the characteristics of the region of interest, e.g. a lesion or an area covering the lesion, before performing the CTP scan, and by adapting the subsequent CTP scan based on the characteristics of the region of interest, the drawback introduced by a limited scan area of the CTP scanner is mitigated, or even overcome.

19. 发明授权

US08488857B2 Automated diagnosis and alignment supplemented with positron emission tomography (PET) and magnetic resonance (MR) flow estimation 有权
标题翻译：自动诊断和对准补充了正电子发射断层扫描（PET）和磁共振（MR）流量估计
公开(公告)号：US08488857B2
公开(公告)日：2013-07-16
申请号：US12529195
申请日：2008-02-14
申请人： Stewart M. Young , Michael Kuhn , Fabian Wenzel , Ingwer C. Carlsen , Kirsten Meetz , Ralph Buchert
发明人： Stewart M. Young , Michael Kuhn , Fabian Wenzel , Ingwer C. Carlsen , Kirsten Meetz , Ralph Buchert
IPC分类号： G06K9/00 , G06K9/62 , A61B5/02
CPC分类号： A61B6/5247 , A61B5/0035 , A61B5/055 , A61B5/4088 , A61B6/037 , A61B6/507
摘要： A scanner (10) is used to provide images for automated diagnoses of neurodegenerative diseases, such as Alzheimers disease. The images are registered (90) to a template (78). The aligned image is analyzed (60) in relation to reference image data (76, 80) which has been registered to the template which is contained in a knowledge maintenance engine (70) for similar patterns of hypo-intensity that would indicate (in the case of an FDG tracer) reduced glucose uptake in the brain. The most appropriate reference images for the analysis of the present study are chosen by a filter (74). The present study is then given a dementia score (84) as a diagnostic feature vector that indicates to a clinician the type and severity of the ailment based on the analysis. The scanner (10) can produce PET or other metabolic and MR images for diagnosis. The MR can be used to measure blood flow rate into the brain. From the blood flow rate and the metabolic image, tracer, e.g. FDG, uptake maps can be generated for use in the automated diagnoses.
摘要翻译：扫描仪（10）用于提供自动诊断神经变性疾病如阿尔茨海默病的图像。将图像（90）注册到模板（78）。对已经注册到包含在知识维护引擎（70）中的模板的参考图像数据（76,80）进行对准的图像的分析（60），用于类似的低强度模式，其将指示（在 FDG示踪剂的情况）降低了脑中的葡萄糖摄取。用于本研究分析的最合适的参考图像由滤波器（74）选择。然后，本研究给予痴呆评分（84）作为诊断特征向量，其基于分析向临床医生指示疾病的类型和严重程度。扫描仪（10）可以产生PET或其他代谢和MR图像进行诊断。 MR可用于测量进入脑部的血液流量。从血流速度和代谢图像，示踪剂，例如，可以生成FDG，摄影图可用于自动诊断。

20. 发明授权

US08045778B2 Hot spot detection, segmentation and identification in pet and spect images 有权
标题翻译：宠物和光谱图像中的热点检测，分割和识别
公开(公告)号：US08045778B2
公开(公告)日：2011-10-25
申请号：US11749218
申请日：2007-05-16
申请人： Thomas Blaffert , Kirsten Meetz , Zuo Zhao
发明人： Thomas Blaffert , Kirsten Meetz , Zuo Zhao
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , G06T7/11 , G06T2207/10104 , G06T2207/10108 , G06T2207/30004 , Y10S128/922
摘要： A potential region of interest segmentation device segments an image data into regions of potential interest. From the regions of potential interest, an identifying device identifies a region of interest including an object of interest based on a set of rules. A recognizing device differentiates among the identified objects of interest and selects at least one particular object of interest.
摘要翻译：潜在的兴趣区域分割装置将图像数据分割成潜在感兴趣的区域。从潜在兴趣的区域，识别装置基于一组规则来识别包括感兴趣对象的感兴趣区域。识别装置区分所识别的感兴趣对象，并选择至少一个特定的感兴趣对象。

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