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11. 发明申请

US20050152895A1 Prevention of adhesions 审中-公开
标题翻译：预防粘连
公开(公告)号：US20050152895A1
公开(公告)日：2005-07-14
申请号：US11002036
申请日：2004-12-02
申请人： Nasser Chegini , James Burns , Michael Diamond , Lena Holmdahl
发明人： Nasser Chegini , James Burns , Michael Diamond , Lena Holmdahl
IPC分类号： C07K16/38 , A61K48/00 , A61K31/728 , A61K39/395 , C07K16/28
CPC分类号： C07K16/38
摘要： Methods for the prevention of adhesion formation involve the administration of therapeutic formulations to a patient which include antibodies to TIMP-1 or TIMP-1 antisense oligonucleotides. The formulations can also include suitable carriers, such as a hyaluronic acid matrix, for optimal administration. The treatment procedure can be initiated and monitored by a diagnostic procedure which involves the detection of elevated levels of TIMP-1 in a patient.
摘要翻译：用于预防粘连形成的方法包括向包括TIMP-1或TIMP-1反义寡核苷酸的抗体的患者施用治疗制剂。制剂还可以包括合适的载体，例如透明质酸基质，用于最佳施用。可以通过涉及检测患者中TIMP-1水平升高的诊断程序来启动和监测治疗程序。

12. 发明申请

US20080025991A1 Use of Aromatase Inhibitors for Treatment of Ectopic Pregnancy 有权
标题翻译：使用芳香酶抑制剂治疗异位妊娠
公开(公告)号：US20080025991A1
公开(公告)日：2008-01-31
申请号：US11664768
申请日：2005-10-04
申请人： Mohamed Mitwally , Michael Diamond , Robert Casper
发明人： Mohamed Mitwally , Michael Diamond , Robert Casper
IPC分类号： A61K31/4196 , A61K31/335 , A61K31/519 , A61K31/566 , A61K31/575 , A61K31/7004 , A61K33/00 , A61K38/12 , A61K39/395 , A61P15/00
CPC分类号： A61K31/4196 , A61K31/56 , A61K31/5685
摘要： Following a diagnosis of ectopic pregnancy, at least one aromatase inhibitor, is administered to a patient, either alone or in combination with other aromatase inhibitors or therapeutic agents or as an adjuvant to conservative surgical treatment, such as laparoscopy, to prevent the establishment and/or continuation of the ectopic pregnancy. In certain preferred embodiments, the aromatase inhibitor is administered in conjunction with methotrexate.
摘要翻译：诊断为异位妊娠后，将至少一种芳香酶抑制剂单独或与其它芳香酶抑制剂或治疗剂组合施用于患者，或作为保守手术治疗如腹腔镜检查的佐剂，以防止建立和/ 或继续宫外孕。在某些优选的实施方案中，芳香酶抑制剂与甲氨蝶呤一起施用。

13. 发明申请

US20080007552A1 Field Changeable Rendering System For A Computing Device 有权
标题翻译：用于计算设备的现场可变渲染系统
公开(公告)号：US20080007552A1
公开(公告)日：2008-01-10
申请号：US11779231
申请日：2007-07-17
申请人： Michael Diamond , Luc Bisson , Ludger Mimberg , Joseph Walters
发明人： Michael Diamond , Luc Bisson , Ludger Mimberg , Joseph Walters
IPC分类号： G06F17/00
CPC分类号： G06F13/409
摘要： One embodiment of a field changeable rendering system includes an output device interfaced to a motherboard, a fixed rendering device mounted to the motherboard for generating information to be output on said output device, a connector for attaching a field-changeable rendering card to the motherboard, said field-changeable rendering card capable of housing a discrete rendering device for generating information to be output on said output device and detection circuitry for detecting that a field-changeable rendering card housing a discrete rendering device is coupled to said connector and causing information from said field-changeable rendering card housing a discrete rendering device to be output on said output device. One advantage of the disclosed edge connector is that it is compatible with a plurality of graphics cards and systems, thereby enabling a computing device user to upgrade the existing device's graphics system. Thus, the user is not forced to purchase an entirely new computing device in order to take advantage of graphics innovations. A further advantage of the disclosed edge connector is that it enables upgrades to low voltage differential signaling (LVDS) features, without the need for additional costly devices capable of operating at LVDS data rates.
摘要翻译：现场可变绘制系统的一个实施例包括与主板接口的输出设备，安装到母板上的固定渲染设备，用于产生要在所述输出设备上输出的信息;连接器，用于将现场可变渲染卡连接到主板; 所述现场可变绘制卡能够容纳用于产生要在所述输出设备上输出的信息的离散渲染设备和用于检测容纳离散渲染设备的现场可变渲染卡耦合到所述连接器并检测来自所述连接器的信息的检测电路现场可变绘制卡，其容纳要在所述输出设备上输出的离散渲染设备。所公开的边缘连接器的一个优点是它与多个图形卡和系统兼容，从而使得计算设备用户能够升级现有设备的图形系统。因此，为了利用图形创新，用户不被迫购买全新的计算设备。所公开的边缘连接器的另一个优点是能够升级到低电压差分信号（LVDS）特征，而不需要能够以LVDS数据速率操作的额外昂贵的设备。

14. 发明申请

US20070162253A1 QUILTING AND SEWING CALCULATOR 审中-公开
标题翻译：查询和缝纫计算器
公开(公告)号：US20070162253A1
公开(公告)日：2007-07-12
申请号：US11610812
申请日：2006-12-14
申请人： Susan Blades , Michael Diamond
发明人： Susan Blades , Michael Diamond
IPC分类号： G06F15/00
CPC分类号： G06F15/02
摘要： The present invention comprises a calculator for performing sewing calculations. The calculator includes a processor and an input device connected to the processor. A display is connected to the processor. Software operates on the processor to receive quilt function operands from the input device. The software calculates quilt function results and displays the quilt function results on the display. A method of performing calculations is also disclosed. The method includes receiving data related to quilt calculations. The results related to the quilt calculations are calculated and the results related to the quilt calculations are displayed.
摘要翻译：本发明包括用于进行缝纫计算的计算器。计算器包括处理器和连接到处理器的输入设备。显示器连接到处理器。软件在处理器上运行，以从输入设备接收被子功能操作数。软件计算被子功能结果，并在显示屏上显示被子功能结果。还公开了执行计算的方法。该方法包括接收与被子计算有关的数据。计算与被子计算相关的结果，并显示与被子计算相关的结果。

15. 发明申请

US20060004536A1 System and method for remotely configuring semiconductor functional circuits 有权
标题翻译：远程配置半导体功能电路的系统和方法
公开(公告)号：US20060004536A1
公开(公告)日：2006-01-05
申请号：US10740779
申请日：2003-12-18
申请人： Michael Diamond , John Montrym , James Van Dyke , Michael Nagy , Sean Treichler
发明人： Michael Diamond , John Montrym , James Van Dyke , Michael Nagy , Sean Treichler
IPC分类号： G01M19/00
CPC分类号： G01R31/318544 , G01R31/31704 , G01R31/3185 , G05B99/00 , G06F11/2289 , G06F11/267 , G06F19/00 , H01L22/22 , H01L2924/0002 , H01L2924/00
摘要： The present invention systems and methods facilitate configuration of functional components included in a remotely located integrated circuit die. In one exemplary implementation, a die functional component reconfiguration request process is engaged in wherein a system requests a reconfiguration code from a remote centralized resource. A reconfiguration code production process is executed in which a request for a reconfiguration code and a permission indicator are received, validity of permission indicator is analyzed, and a reconfiguration code is provided if the permission indicator is valid. A die functional component configuration process is performed on the die when an appropriate reconfiguration code is received by the die. The functional component configuration process includes directing alteration of a functional component configuration. Workflow is diverted from disabled functional components to enabled functional components.
摘要翻译：本发明的系统和方法有助于配置在远程定位的集成电路管芯中的功能部件。在一个示例性实现中，引入管芯功能部件重新配置请求过程，其中系统从远程集中资源请求重新配置代码。执行重新配置代码生成处理，其中接收到重新配置代码和许可指示符的请求，分析许可指示符的有效性，并且如果许可指示符有效，则提供重新配置代码。当芯片接收到适当的重新配置代码时，在管芯上执行管芯功能部件配置处理。功能组件配置过程包括引导功能组件配置的改变。工作流程从禁用的功能组件转移到启用的功能组件。

16. 发明申请

US20050278666A1 System and method for testing and configuring semiconductor functional circuits 有权
标题翻译：用于测试和配置半导体功能电路的系统和方法
公开(公告)号：US20050278666A1
公开(公告)日：2005-12-15
申请号：US10876340
申请日：2004-06-23
申请人： Michael Diamond
发明人： Michael Diamond
IPC分类号： G06F11/00 , G06F17/50 , G06F19/00
CPC分类号： G06F11/267 , G01R31/31704 , G01R31/3185 , G06F11/27 , H01L22/22 , H01L2924/0002 , H01L2924/00
摘要： The present invention systems and methods enable configuration of functional components in integrated circuits. A present invention system and method can flexibly change the operational characteristics of functional components in an integrated circuit die based upon a variety of factors including manufacturing defects, compatibility characteristics, performance requirements, and system health (e.g., the number of components operating properly). Functional component operational behavior is tested and analyzed at various levels of configuration abstraction and component organization (e.g., topological inversion analysis). The testing and analysis can be performed in parallel on numerous functional components. Functional component configuration related information is presented in a graphical user interface (GUI) at various levels of granularity and in real time. The graphical user interface can facilitate user interaction in recognizing failure patterns, production test tuning and field configuration algorithm adjustment. The testing and analysis information can also be organized in a variety of convenient database formats.
摘要翻译：本发明的系统和方法能够在集成电路中配置功能部件。本发明的系统和方法可以基于包括制造缺陷，兼容特性，性能要求和系统健康性（例如，正确地操作的部件的数量）的各种因素灵活地改变集成电路管芯中的功能部件的操作特性。功能组件操作行为在各种配置抽象和组件组织级别（例如，拓扑反演分析）下进行测试和分析。测试和分析可以在许多功能组件上并行执行。功能组件配置相关信息以不同的粒度级别和实时呈现在图形用户界面（GUI）中。图形用户界面可以方便用户在识别故障模式，生产测试调整和现场配置算法调整时进行交互。测试和分析信息也可以以各种方便的数据库格式进行组织。

17. 发明申请

US20090258011A1 Antibodies against west nile virus and therapeutic and prophylactic uses thereof 有权
标题翻译：抗西尼罗病毒的抗体及其治疗和预防用途
公开(公告)号：US20090258011A1
公开(公告)日：2009-10-15
申请号：US12385346
申请日：2009-04-06
申请人： Michael Diamond , Theodore Oliphant , Christopher Michael Doane
发明人： Michael Diamond , Theodore Oliphant , Christopher Michael Doane
IPC分类号： A61K39/42 , A61P31/12
CPC分类号： C07K16/1081 , A61K2039/505 , C07K2317/734 , C07K2317/76 , Y02A50/394
摘要： The present invention relates to compositions comprising antibodies or fragments thereof that immunospecifically bind to one or more antigens of a flavivirus, particularly of West Nile Virus (WNV), and methods for preventing, treating or ameliorating symptoms associated with a flavivirus, particularly of West Nile Virus (WNV), infection utilizing said compositions. In particular, the present invention relates to methods for preventing, treating or ameliorating symptoms associated with WNV infection, said methods comprising administering to a human subject an effective amount of one or more antibodies or fragments thereof that immunospecifically bind to a WNV antigen. The present invention also relates to detectable or diagnostic compositions comprising antibodies or fragments thereof that immunospecifically bind to a WNV antigen and methods for detecting or diagnosing WNV infection utilizing said compositions.
摘要翻译：本发明涉及包含免疫特异性结合黄病毒，特别是西尼罗病毒（WNV）的一种或多种抗原的抗体或其片段的组合物，以及用于预防，治疗或改善黄病毒特别是西尼罗病毒症状的方法病毒（WNV），利用所述组合物的感染。特别地，本发明涉及用于预防，治疗或改善与WNV感染相关的症状的方法，所述方法包括向人类受试者施用有效量的一种或多种免疫特异性结合WNV抗原的抗体或其片段。本发明还涉及包含免疫特异性结合WNV抗原的抗体或其片段的可检测或诊断组合物，以及利用所述组合物检测或诊断WNV感染的方法。

18. 发明授权

US07527973B2 Antibodies against West Nile Virus and therapeutic and prophylactic uses thereof 有权
标题翻译：抗西尼罗病毒抗体及其治疗和预防用途
公开(公告)号：US07527973B2
公开(公告)日：2009-05-05
申请号：US11159046
申请日：2005-06-21
申请人： Michael Diamond , Theodore Oliphant , Christopher Michael Doane
发明人： Michael Diamond , Theodore Oliphant , Christopher Michael Doane
IPC分类号： C12N5/06 , C12N5/10 , C12P21/01 , A61K49/00 , A61K39/395 , A61K39/42 , A61K39/12 , A61K39/193
CPC分类号： C07K16/1081 , A61K2039/505 , C07K2317/734 , C07K2317/76 , Y02A50/394
摘要： The present invention relates to compositions comprising antibodies or fragments thereof that immunospecifically bind to one or more antigens of a flavivirus, particularly of West Nile Virus (WNV), and methods for preventing, treating or ameliorating symptoms associated with a flavivirus, particularly of West Nile Virus (WNV), infection utilizing said compositions. In particular, the present invention relates to methods for preventing, treating or ameliorating symptoms associated with WNV infection, said methods comprising administering to a human subject an effective amount of one or more antibodies or fragments thereof that immunospecifically bind to a WNV antigen. The present invention also relates to detectable or diagnostic compositions comprising antibodies or fragments thereof that immunospecifically bind to a WNV antigen and methods for detecting or diagnosing WNV infection utilizing said compositions.
摘要翻译：本发明涉及包含免疫特异性结合黄病毒，特别是西尼罗病毒（WNV）的一种或多种抗原的抗体或其片段的组合物，以及用于预防，治疗或改善黄病毒特别是西尼罗病毒症状的方法病毒（WNV），利用所述组合物的感染。特别地，本发明涉及用于预防，治疗或改善与WNV感染相关的症状的方法，所述方法包括向人类受试者施用有效量的一种或多种免疫特异性结合WNV抗原的抗体或其片段。本发明还涉及包含免疫特异性结合WNV抗原的抗体或其片段的可检测或诊断组合物，以及利用所述组合物检测或诊断WNV感染的方法。

19. 发明申请

US20050251761A1 Integrated circuit configuration system and method 有权
标题翻译：集成电路配置系统及方法
公开(公告)号：US20050251761A1
公开(公告)日：2005-11-10
申请号：US10740722
申请日：2003-12-18
申请人： Michael Diamond , John Montrym , James Van Dyke , Michael Nagy , Sean Treichler
发明人： Michael Diamond , John Montrym , James Van Dyke , Michael Nagy , Sean Treichler
IPC分类号： G01M19/00 , G01R31/26 , G06F11/00 , G06F11/267 , G06F17/50 , G09G5/02
CPC分类号： G01R31/318544 , G01R31/31704 , G01R31/3185 , G05B99/00 , G06F11/2289 , G06F11/267 , G06F19/00 , H01L22/22 , H01L2924/0002 , H01L2924/00
摘要： The present invention systems and methods enable configuration of functional components in integrated circuits. A present invention system and method can flexibly change the operational characteristics of functional components in an integrated circuit die based upon a variety of factors. In one embodiment, manufacturing yields, compatibility characteristics, performance requirements, and system health (e.g., the number of components operating properly) are factored into changes to the operational characteristics of functional components. In one exemplary implementation, the changes to operational characteristics of a functional component are coordinated with changes to other functional components. Workflow scheduling and distribution is also adjusted based upon the changes to the operational characteristics of the functional components. For example, a functional component configuration controller changes the operational characteristics settings and provides an indication to a workflow distribution component. The workflow distribution component changes the workflow schedule based upon the operational characteristics settings (e.g., work flow is diverted to or away from functional components).
摘要翻译：本发明的系统和方法能够在集成电路中配置功能部件。本发明的系统和方法可以基于各种因素灵活地改变集成电路管芯中的功能部件的操作特性。在一个实施例中，制造产量，兼容性特性，性能要求和系统健康状况（例如，正确操作的组件的数量）被归因于对功能组件的操作特性的改变。在一个示例性实现中，对功能组件的操作特性的改变与对其他功能组件的改变协调。工作流程调度和分配也会根据功能组件的运行特性的变化进行调整。例如，功能组件配置控制器改变操作特征设置并向工作流分发组件提供指示。工作流分发组件根据操作特性设置（例如，工作流被转移到或远离功能组件）改变工作流调度。

20. 发明申请

US20050228928A1 Method and apparatus for routing graphics processing signals to a stand-alone module 有权
标题翻译：将图形处理信号路由到独立模块的方法和装置
公开(公告)号：US20050228928A1
公开(公告)日：2005-10-13
申请号：US10879877
申请日：2004-06-28
申请人： Michael Diamond
发明人： Michael Diamond
IPC分类号： G06F13/00 , G06F13/14 , G06F13/40
CPC分类号： G06F13/409
摘要： One embodiment of a connector for a stand-alone graphics module is adapted for coupling a computing device to the stand-alone graphics module, which is external to the computing device. The connector is adapted for receiving a PCI express signal from the computing device and for delivering the PCI express signal to the stand-alone graphics module. The connector is further adapted for receiving display output signals from the stand-alone graphics module and delivering the display output signals to the computing system, e.g., for use in accordance with one or more output display panels coupled to said computing device.
摘要翻译：用于独立图形模块的连接器的一个实施例适于将计算设备耦合到在计算设备外部的独立图形模块。连接器适于从计算设备接收PCI express信号，并将PCI express信号传送到独立图形模块。连接器还适于从独立图形模块接收显示输出信号，并将显示输出信号传送到计算系统，例如用于根据耦合到所述计算设备的一个或多个输出显示面板使用。

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