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1. 发明授权

US07981422B2 Antibodies against West Nile Virus and therapeutic and prophylactic uses thereof 有权
标题翻译：抗西尼罗病毒抗体及其治疗和预防用途
公开(公告)号：US07981422B2
公开(公告)日：2011-07-19
申请号：US12385346
申请日：2009-04-06
申请人： Michael Diamond , Theodore Oliphant , Christopher Michael Doane
发明人： Michael Diamond , Theodore Oliphant , Christopher Michael Doane
IPC分类号： A61K39/42
CPC分类号： C07K16/1081 , A61K2039/505 , C07K2317/734 , C07K2317/76 , Y02A50/394
摘要： The present invention relates to compositions comprising antibodies or fragments thereof that immunospecifically bind to one or more antigens of a flavivirus, particularly of West Nile Virus (WNV), and methods for preventing, treating or ameliorating symptoms associated with a flavivirus, particularly of West Nile Virus (WNV), infection utilizing said compositions. In particular, the present invention relates to methods for preventing, treating or ameliorating symptoms associated with WNV infection, said methods comprising administering to a human subject an effective amount of one or more antibodies or fragments thereof that immunospecifically bind to a WNV antigen. The present invention also relates to detectable or diagnostic compositions comprising antibodies or fragments thereof that immunospecifically bind to a WNV antigen and methods for detecting or diagnosing WNV infection utilizing said compositions.
摘要翻译：本发明涉及包含免疫特异性结合黄病毒，特别是西尼罗病毒（WNV）的一种或多种抗原的抗体或其片段的组合物，以及用于预防，治疗或改善黄病毒特别是西尼罗病毒症状的方法病毒（WNV），利用所述组合物的感染。特别地，本发明涉及用于预防，治疗或改善与WNV感染相关的症状的方法，所述方法包括向人类受试者施用有效量的一种或多种免疫特异性结合WNV抗原的抗体或其片段。本发明还涉及包含免疫特异性结合WNV抗原的抗体或其片段的可检测或诊断组合物，以及利用所述组合物检测或诊断WNV感染的方法。

2. 发明申请

US20090258011A1 Antibodies against west nile virus and therapeutic and prophylactic uses thereof 有权
标题翻译：抗西尼罗病毒的抗体及其治疗和预防用途
公开(公告)号：US20090258011A1
公开(公告)日：2009-10-15
申请号：US12385346
申请日：2009-04-06
申请人： Michael Diamond , Theodore Oliphant , Christopher Michael Doane
发明人： Michael Diamond , Theodore Oliphant , Christopher Michael Doane
IPC分类号： A61K39/42 , A61P31/12
CPC分类号： C07K16/1081 , A61K2039/505 , C07K2317/734 , C07K2317/76 , Y02A50/394
摘要： The present invention relates to compositions comprising antibodies or fragments thereof that immunospecifically bind to one or more antigens of a flavivirus, particularly of West Nile Virus (WNV), and methods for preventing, treating or ameliorating symptoms associated with a flavivirus, particularly of West Nile Virus (WNV), infection utilizing said compositions. In particular, the present invention relates to methods for preventing, treating or ameliorating symptoms associated with WNV infection, said methods comprising administering to a human subject an effective amount of one or more antibodies or fragments thereof that immunospecifically bind to a WNV antigen. The present invention also relates to detectable or diagnostic compositions comprising antibodies or fragments thereof that immunospecifically bind to a WNV antigen and methods for detecting or diagnosing WNV infection utilizing said compositions.
摘要翻译：本发明涉及包含免疫特异性结合黄病毒，特别是西尼罗病毒（WNV）的一种或多种抗原的抗体或其片段的组合物，以及用于预防，治疗或改善黄病毒特别是西尼罗病毒症状的方法病毒（WNV），利用所述组合物的感染。特别地，本发明涉及用于预防，治疗或改善与WNV感染相关的症状的方法，所述方法包括向人类受试者施用有效量的一种或多种免疫特异性结合WNV抗原的抗体或其片段。本发明还涉及包含免疫特异性结合WNV抗原的抗体或其片段的可检测或诊断组合物，以及利用所述组合物检测或诊断WNV感染的方法。

3. 发明授权

US07527973B2 Antibodies against West Nile Virus and therapeutic and prophylactic uses thereof 有权
标题翻译：抗西尼罗病毒抗体及其治疗和预防用途
公开(公告)号：US07527973B2
公开(公告)日：2009-05-05
申请号：US11159046
申请日：2005-06-21
申请人： Michael Diamond , Theodore Oliphant , Christopher Michael Doane
发明人： Michael Diamond , Theodore Oliphant , Christopher Michael Doane
IPC分类号： C12N5/06 , C12N5/10 , C12P21/01 , A61K49/00 , A61K39/395 , A61K39/42 , A61K39/12 , A61K39/193
CPC分类号： C07K16/1081 , A61K2039/505 , C07K2317/734 , C07K2317/76 , Y02A50/394
摘要： The present invention relates to compositions comprising antibodies or fragments thereof that immunospecifically bind to one or more antigens of a flavivirus, particularly of West Nile Virus (WNV), and methods for preventing, treating or ameliorating symptoms associated with a flavivirus, particularly of West Nile Virus (WNV), infection utilizing said compositions. In particular, the present invention relates to methods for preventing, treating or ameliorating symptoms associated with WNV infection, said methods comprising administering to a human subject an effective amount of one or more antibodies or fragments thereof that immunospecifically bind to a WNV antigen. The present invention also relates to detectable or diagnostic compositions comprising antibodies or fragments thereof that immunospecifically bind to a WNV antigen and methods for detecting or diagnosing WNV infection utilizing said compositions.
摘要翻译：本发明涉及包含免疫特异性结合黄病毒，特别是西尼罗病毒（WNV）的一种或多种抗原的抗体或其片段的组合物，以及用于预防，治疗或改善黄病毒特别是西尼罗病毒症状的方法病毒（WNV），利用所述组合物的感染。特别地，本发明涉及用于预防，治疗或改善与WNV感染相关的症状的方法，所述方法包括向人类受试者施用有效量的一种或多种免疫特异性结合WNV抗原的抗体或其片段。本发明还涉及包含免疫特异性结合WNV抗原的抗体或其片段的可检测或诊断组合物，以及利用所述组合物检测或诊断WNV感染的方法。

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