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1. 发明申请

US20050152895A1 Prevention of adhesions 审中-公开
标题翻译：预防粘连
公开(公告)号：US20050152895A1
公开(公告)日：2005-07-14
申请号：US11002036
申请日：2004-12-02
申请人： Nasser Chegini , James Burns , Michael Diamond , Lena Holmdahl
发明人： Nasser Chegini , James Burns , Michael Diamond , Lena Holmdahl
IPC分类号： C07K16/38 , A61K48/00 , A61K31/728 , A61K39/395 , C07K16/28
CPC分类号： C07K16/38
摘要： Methods for the prevention of adhesion formation involve the administration of therapeutic formulations to a patient which include antibodies to TIMP-1 or TIMP-1 antisense oligonucleotides. The formulations can also include suitable carriers, such as a hyaluronic acid matrix, for optimal administration. The treatment procedure can be initiated and monitored by a diagnostic procedure which involves the detection of elevated levels of TIMP-1 in a patient.
摘要翻译：用于预防粘连形成的方法包括向包括TIMP-1或TIMP-1反义寡核苷酸的抗体的患者施用治疗制剂。制剂还可以包括合适的载体，例如透明质酸基质，用于最佳施用。可以通过涉及检测患者中TIMP-1水平升高的诊断程序来启动和监测治疗程序。

2. 发明授权

US08035645B2 Graphics processing system including at least three bus devices 有权
标题翻译：图形处理系统包括至少三个总线设备
公开(公告)号：US08035645B2
公开(公告)日：2011-10-11
申请号：US12615802
申请日：2009-11-10
申请人： Franck R. Diard , Michael Diamond
发明人： Franck R. Diard , Michael Diamond
IPC分类号： G06T1/20 , G06F15/16 , G06F16/80
CPC分类号： G06T15/005 , G06T1/20 , G06T2210/52
摘要： Multichip graphics processing subsystems include at least three distinct graphics devices (e.g., expansion cards) coupled to a high-speed bus (e.g., a PCI Express bus) and operable in a distributed rendering mode. One of the graphics devices provides pixel data to a display device, and at least one of the other graphics devices transfers the pixel data it generates to another of the devices via the bus to be displayed. Where the high-speed bus provides data transfer lanes, allocation of lanes among the graphics devices can be optimized.
摘要翻译：多芯片图形处理子系统包括耦合到高速总线（例如，PCI Express总线）并可在分布式渲染模式下操作的至少三个不同的图形设备（例如，扩展卡）。其中一个图形设备向显示设备提供像素数据，并且至少其中一个图形设备经由要显示的总线将其生成的像素数据传送到另一设备。在高速总线提供数据传输通道的地方，可以优化图形设备之间的通道分配。

3. 发明申请

US20090164908A1 USING A SCALABLE GRAPHICS SYSTEM TO ENABLE A GENERAL-PURPOSE MULTI-USER COMPUTER SYSTEM 有权
标题翻译：使用可扩展的图形系统启用一般用途的多用户计算机系统
公开(公告)号：US20090164908A1
公开(公告)日：2009-06-25
申请号：US12395685
申请日：2009-03-01
申请人： Michael Diamond
发明人： Michael Diamond
IPC分类号： G06F3/048 , G06T15/00 , G06F15/16
CPC分类号： G06T1/20
摘要： A graphics system is disclosed. The graphics system includes at least one GPU (graphics processing unit) for processing a compute workload. The graphics system uses a multi-user manager for allocating the compute workload capability for each one of a plurality of users. Each user will use an access terminal.
摘要翻译：公开了一种图形系统。图形系统包括用于处理计算工作负载的至少一个GPU（图形处理单元）。图形系统使用多用户管理器来为多个用户中的每个用户分配计算工作负载能力。每个用户将使用接入终端。

4. 发明申请

US20080106328A1 Semiconductor die micro electro-mechanical switch management system and method 有权
标题翻译：半导体模具微机电开关管理系统及方法
公开(公告)号：US20080106328A1
公开(公告)日：2008-05-08
申请号：US12005691
申请日：2007-12-28
申请人： Michael Diamond
发明人： Michael Diamond
IPC分类号： G05F1/10 , H01L21/62
CPC分类号： G06F1/3203 , G06F1/3287 , H01H1/0036 , H01H2001/0084 , Y02D10/171
摘要： A die micro electro-mechanical switch management system and method facilitate power conservation by selectively preventing electrical current from flowing in designated components. A present invention semiconductor die comprises a block of transistors for performing switching operations, a bus (e.g., a power bus, a signal bus, etc.) for conveying electrical current and a micro electro-mechanical switch that couples and decouples the block of transistors to and from the bus. The micro electro-mechanical switch is opened and closed depending upon operations (e.g., switching operations) being performed by the block of transistors. Electrical current is prevented from flowing to the block of transistors when the micro electro-mechanical switch is open and the block of transistors is electrically isolated. The micro electro-mechanical switch can interrupt electrical current flow in a plurality of the bus lines and/or can be included in a relay array.
摘要翻译：模具微机电开关管理系统和方法通过选择性地防止电流在指定部件中流动来促进功率节省。本发明的半导体管芯包括用于执行开关操作的晶体管块，用于传送电流的总线（例如，电源总线，信号总线等）和耦合和去耦合晶体管的微机电开关往返公车。根据由晶体管块执行的操作（例如，开关操作），微机电开关被打开和关闭。当微机电开关断开并且晶体管块电隔离时，防止电流流向晶体管块。微机电开关可以中断多个总线中的电流和/或可以包括在中继阵列中。

5. 发明申请

US20050285865A1 Method and system for a scalable discrete graphics system 有权
标题翻译：可扩展离散图形系统的方法和系统
公开(公告)号：US20050285865A1
公开(公告)日：2005-12-29
申请号：US10877723
申请日：2004-06-25
申请人： Michael Diamond
发明人： Michael Diamond
IPC分类号： G06F3/14 , G06F13/14 , G06F13/40
CPC分类号： G06F13/4027 , G06F3/14 , G06F2213/0026
摘要： A scalable discrete graphics system (DGS) is disclosed. The DGS includes a serial bus bridge configured to couple a plurality of GPUs to a serial bus. A serial bus connector is coupled to the serial bus bridge. A system chassis coupled to the serial bus bridge and the serial bus connector and configured to house the GPUs. The serial bus connector is configured to removably connect to a computer system. The GPUs access the computer system via the serial bus bridge and the serial bus connector to cooperatively execute 3-D graphics instructions from the computer system.
摘要翻译：公开了可扩展的分立图形系统（DGS）。 DGS包括被配置为将多个GPU耦合到串行总线的串行总线桥。串行总线连接器耦合到串行总线桥。耦合到串行总线桥和串行总线连接器并被配置为容纳GPU的系统机箱。串行总线连接器被配置为可移除地连接到计算机系统。 GPU通过串行总线桥接器和串行总线连接器访问计算机系统，从计算机系统协同执行3-D图形指令。

6. 发明申请

US20050285864A1 Method and system for stand alone graphics independent of computer system form factor 有权
标题翻译：独立显卡的方法和系统独立于计算机系统外形
公开(公告)号：US20050285864A1
公开(公告)日：2005-12-29
申请号：US10877642
申请日：2004-06-25
申请人： Michael Diamond , Cesar Carrera
发明人： Michael Diamond , Cesar Carrera
IPC分类号： G06F13/14 , G06F15/00 , G06F15/16 , G06T1/00
CPC分类号： G06F1/3203 , A63F2300/203 , G06F1/18 , G06F1/206 , G06F1/3281 , G06F3/14 , G09G5/363 , Y02D10/158
摘要： A discrete graphics system (DGS) for executing 3D graphics instructions for a computer system is disclosed. The discrete graphics system includes a GPU for executing 3D graphics instructions and a DGS system chassis configured to house the GPU. A serial bus connector coupled is to the GPU and the DGS chassis. The serial bus connector is configured to removably connect the DGS and the GPU to the computer system. The GPU of the DGS accesses the computer system via the serial bus connector to execute the 3D graphics instructions for the computer system.
摘要翻译：公开了一种用于执行计算机系统的3D图形指令的分立图形系统（DGS）。分立图形系统包括用于执行3D图形指令的GPU和被配置为容纳GPU的DGS系统机箱。串行总线连接器耦合到GPU和DGS机箱。串行总线连接器被配置为将DGS和GPU可拆卸地连接到计算机系统。 DGS的GPU通过串行总线连接器访问计算机系统，以执行计算机系统的3D图形指令。

7. 发明申请

US20050285863A1 Discrete graphics system unit for housing a GPU 有权
标题翻译：用于容纳GPU的分立图形系统单元
公开(公告)号：US20050285863A1
公开(公告)日：2005-12-29
申请号：US10877724
申请日：2004-06-25
申请人： Michael Diamond
发明人： Michael Diamond
IPC分类号： G06F13/14 , G06T15/00 , G09G5/00 , G09G5/36 , G09G5/395
CPC分类号： G09G5/363 , G06F3/1438 , G06T15/00 , G09G3/003 , G09G5/003 , G09G5/395 , G09G2330/021 , G09G2360/06
摘要： A DGS (discrete graphics system) unit is disclosed. The DGS unit includes a system chassis configured to house a GPU, the GPU for executing 3-D graphics instructions, and a GPU mounting unit coupled to the system chassis and configured to receive the GPU. A serial bus connector is coupled to the chassis and is coupled to the GPU mounting unit, wherein the serial bus connector is configured removably connect the GPU to a computer system to enable the GPU to access the computer system via the serial bus connector and execute the 3-D graphics instructions for the computer system. A power supply coupled to the system chassis for supplying power to the GPU independent of the computer system.
摘要翻译：公开了一种DGS（分立图形系统）单元。 DGS单元包括被配置为容纳GPU的系统机箱，用于执行3-D图形指令的GPU和耦合到系统机箱并被配置为接收GPU的GPU安装单元。串行总线连接器耦合到机箱并且耦合到GPU安装单元，其中串行总线连接器被配置为可拆卸地将GPU连接到计算机系统，以使GPU能够经由串行总线连接器访问计算机系统，并执行计算机系统的3-D图形指令。耦合到系统机箱的电源，用于独立于计算机系统向GPU供电。

8. 发明申请

US20080045484A1 Use of Aromatase Inhibitors for Endometrial Thinning in Preparation for Surgical Procedures on the Endometrial Cavity and Uterus 有权
标题翻译：使用芳香酶抑制剂进行子宫内膜变薄制备子宫内膜和子宫外科手术
公开(公告)号：US20080045484A1
公开(公告)日：2008-02-21
申请号：US11661948
申请日：2005-10-04
申请人： Mohamed Mitwally , Michael Diamond , Robert Casper
发明人： Mohamed Mitwally , Michael Diamond , Robert Casper
IPC分类号： A61K31/4192 , A61K31/56 , A61K31/655 , A61P15/00 , A61P41/00
CPC分类号： A61K31/56 , A61K31/4196 , A61K31/5685 , A61K45/06 , A61K2300/00
摘要： Aromatase inhibitors are administered to a female patient prior to endometrial ablation or resection procedures in order to thin the endometrium to a thickness of less than 6 mm, and preferably less than 4 mm, so as to enhance the treatment outcome. Of course, administration of aromatase inhibitors would be useful for other surgical procedures on the endometrial cavity and the uterus. Commercially available aromatase inhibitors, including, the nonsteroidal preparations, anastrozole and letrozole, and a steroidal agent, exemestane, are well-tolerated, and have been shown to decrease serum estrogen levels. The aromatase inhibitor can be used alone, or in combination with other aromatase inhibitors or pharmaceutical agents, such as hormones.
摘要翻译：在子宫内膜消融或切除手术之前，向女性患者施用芳香酶抑制剂，以将子宫内膜稀薄至小于6mm，优选小于4mm的厚度，以增强治疗结果。当然，芳香酶抑制剂的施用对于子宫内膜和子宫上的其它外科手术是有用的。包括非甾体制剂，阿那曲唑和来曲唑和类固醇剂依西美坦的市售芳香酶抑制剂具有良好的耐受性，并已显示降低血清雌激素水平。芳香酶抑制剂可以单独使用或与其它芳香酶抑制剂或药剂如激素组合使用。

9. 发明申请

US20060067940A1 Antibodies against West Nile Virus and therapeutic and prophylactic uses thereof 有权
公开(公告)号：US20060067940A1
公开(公告)日：2006-03-30
申请号：US11159046
申请日：2005-06-21
申请人： Michael Diamond , Theodore Oliphant , Christopher Doane
发明人： Michael Diamond , Theodore Oliphant , Christopher Doane
IPC分类号： A61K39/42 , C12Q1/70 , C07H21/04 , C12P21/06 , C12N15/86 , C12N5/06 , C07K16/08
CPC分类号： C07K16/1081 , A61K2039/505 , C07K2317/734 , C07K2317/76 , Y02A50/394
摘要： The present invention relates to compositions comprising antibodies or fragments thereof that immunospecifically bind to one or more antigens of a flavivirus, particularly of West Nile Virus (WNV), and methods for preventing, treating or ameliorating symptoms associated with a flavivirus, particularly of West Nile Virus (WNV), infection utilizing said compositions. In particular, the present invention relates to methods for preventing, treating or ameliorating symptoms associated with WNV infection, said methods comprising administering to a human subject an effective amount of one or more antibodies or fragments thereof that immunospecifically bind to a WNV antigen. The present invention also relates to detectable or diagnostic compositions comprising antibodies or fragments thereof that immunospecifically bind to a WNV antigen and methods for detecting or diagnosing WNV infection utilizing said compositions.

10. 发明申请

US20050225549A1 Field changeable rendering system for a computing device 有权
标题翻译：用于计算设备的现场可变绘制系统
公开(公告)号：US20050225549A1
公开(公告)日：2005-10-13
申请号：US10822015
申请日：2004-04-09
申请人： Michael Diamond , Luc Bisson , Ludger Mimberg , Joseph Walters
发明人： Michael Diamond , Luc Bisson , Ludger Mimberg , Joseph Walters
IPC分类号： G06F13/00 , G06F13/14 , G06F13/40
CPC分类号： G06F13/409
摘要： One embodiment of a field changeable rendering system includes an output device interfaced to a motherboard, a fixed rendering device mounted to the motherboard for generating information to be output on said output device, a connector for attaching a field-changeable rendering card to the motherboard, said field-changeable rendering card capable of housing a discrete rendering device for generating information to be output on said output device and detection circuitry for detecting that a field-changeable rendering card housing a discrete rendering device is coupled to said connector and causing information from said field-changeable rendering card housing a discrete rendering device to be output on said output device. One advantage of the disclosed edge connector is that it is compatible with a plurality of graphics cards and systems, thereby enabling a computing device user to upgrade the existing device's graphics system. Thus, the user is not forced to purchase an entirely new computing device in order to take advantage of graphics innovations. A further advantage of the disclosed edge connector is that it enables upgrades to low voltage differential signaling (LVDS) features, without the need for additional costly devices capable of operating at LVDS data rates.
摘要翻译：现场可变绘制系统的一个实施例包括与主板接口的输出设备，安装到母板上的固定渲染设备，用于产生要在所述输出设备上输出的信息;连接器，用于将现场可变渲染卡连接到主板; 所述现场可变绘制卡能够容纳用于产生要在所述输出设备上输出的信息的离散渲染设备和用于检测容纳离散渲染设备的现场可变渲染卡耦合到所述连接器并检测来自所述连接器的信息的检测电路现场可变绘制卡，其容纳要在所述输出设备上输出的离散渲染设备。所公开的边缘连接器的一个优点是它与多个图形卡和系统兼容，从而使得计算设备用户能够升级现有设备的图形系统。因此，为了利用图形创新，用户不被迫购买全新的计算设备。所公开的边缘连接器的另一个优点是能够升级到低电压差分信号（LVDS）特征，而不需要能够以LVDS数据速率操作的额外昂贵的设备。

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