专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

US4202340A Method and apparatus for monitoring heart activity, detecting abnormalities, and cardioverting a malfunctioning heart 失效
标题翻译：用于监测心脏活动的方法和装置，检测异常，以及心脏复苏心脏
公开(公告)号：US4202340A
公开(公告)日：1980-05-13
申请号：US878005
申请日：1978-02-15
申请人： Alois A. Langer , Marlin S. Heilman , Morton M. Mower , Mieczyslaw Mirowski
发明人： Alois A. Langer , Marlin S. Heilman , Morton M. Mower , Mieczyslaw Mirowski
IPC分类号： A61B5/046 , A61N1/362 , A61N1/39 , A61N1/36
CPC分类号： A61N1/3956 , A61B5/046 , A61N1/3621 , A61N1/3987
摘要： Disclosed is a method and an apparatus for monitoring heart activity, for indicating or detecting abnormalities in such activity, and for taking corrective measures to return an arrhythmic heart to normal sinus rhythm. In one embodiment, monitoring and detecting are accomplished by developing a probability density function from ECG signals, or by sampling at least two portions of a probability density function. In another embodiment, a phase lock loop circuit is utilized to indicate fibrillation by the loop's inability to lock onto R--R interval signals. And in still another embodiment, cardiac electrodes are used to sense pulsatile impedance changes, absent in the presence of fibrillation. Also disclosed is a two-stage detector whose second stage is brought out of a stand-by state only after an arrhythmic condition is indicated by the first stage.
摘要翻译：公开了一种用于监测心脏活动的方法和装置，用于指示或检测此类活动中的异常，并采取矫正措施使心律失常心脏恢复正常窦性心律。在一个实施例中，通过从ECG信号开发概率密度函数或通过对概率密度函数的至少两部分进行采样来实现监视和检测。在另一个实施例中，使用锁相环电路来指示环路无法锁定到R-R间隔信号上的原纤化。并且在另一个实施例中，心脏电极用于感测在存在原纤维化时不存在的脉动阻抗变化。还公开了两级检测器，其仅在第一级指示了心律不齐的状态之后，使其第二级脱离待用状态。

12. 发明授权

US4030509A Implantable electrodes for accomplishing ventricular defibrillation and pacing and method of electrode implantation and utilization 失效
标题翻译：用于实现心室除颤和起搏的植入式电极和电极植入和利用的方法
公开(公告)号：US4030509A
公开(公告)日：1977-06-21
申请号：US620026
申请日：1975-09-30
申请人： Marlin S. Heilman , Alois A. Langer , Mieczyslaw Mirowski , Morton M. Mower , David M. Reilly
发明人： Marlin S. Heilman , Alois A. Langer , Mieczyslaw Mirowski , Morton M. Mower , David M. Reilly
IPC分类号： A61N1/05 , A61N1/39 , A61N1/36
CPC分类号： A61N1/3918 , A61N1/0587
摘要： Disclosed are several embodiments of an electrode system for ventricular defibrillation, and the methods of using and implanting the electrode system. In one embodiment, the electrodes are in a generally base-apex configuration having a split conformal base electrode residing above the base of the ventricles (a transecting plane separating the atria from the ventricles) in the region of the atria and a conformal apex electrode in the form of a rotated conic section residing at the apex of the heart. In another embodiment, defibrillation is accomplished by the apex electrode acting against a catheter electrode situated high in the heart or in the superior vena cava.The electrodes themselves are in the form of planar metallic mesh elements adapted to lie in contact with body tissue on an active surface, insulated on the opposite surface. In another embodiment, the conductive portions of the respective electrodes are developed from metallic plates, exposed on one surface and insulated on the other. The electrodes may be split, or may entirely surround the base and apex of the heart.The disclosed electrode system is well adapted for easy implantation during an open heart surgery, or in a separate operation which can be performed in the mediastinal space without intrusion of the pleural space. The electrode system may be implanted for immediate stand-by defibrillation, or may be implanted during open heart surgery, used for post-operative monitoring, pacing and defibrillation, should the need arise, and then subcutaneously implanted for future association with an automatic defibrillating pulse generator. When employed after open heart surgery, the electrode system is preferably equipped with independent atrial and ventricular pacer electrodes.Also disclosed are techniques for fixing the electrode system to the surrounding body tissue, and electrode leads which may be removed after the implanted electrodes have served their desired function, without disturbing the electrodes themselves.
摘要翻译：公开了用于心室除颤的电极系统的几个实施例，以及使用和植入电极系统的方法。在一个实施例中，电极处于大致基部顶点形状，其具有位于心房的区域中的心室的基部（在心房与心室分开的截面）之上的分裂的适形基底电极，以及保形顶点电极居住在心脏顶点的旋转锥体部分的形式。在另一个实施例中，除颤是通过顶点电极来实现的，所述顶点电极作用在位于心脏高处或上腔静脉的导管电极上。

13. 发明授权

US5569181A Sterility assurance for contrast delivery system 失效
标题翻译：造影剂系统的无菌保证
公开(公告)号：US5569181A
公开(公告)日：1996-10-29
申请号：US144845
申请日：1993-10-28
申请人： Marlin S. Heilman , Arthur E. Uber, III
发明人： Marlin S. Heilman , Arthur E. Uber, III
IPC分类号： A61M5/14 , A61M5/00 , A61M5/142 , A61M5/168 , A61M5/172 , A61M31/00 , A61J3/00
CPC分类号： A61M5/142 , A61M5/007 , A61M5/16827 , A61M5/16886 , A61M5/172 , A61M2205/12
摘要： Apparatus and process for injection of a multiple number of patients with a sterile fluid while assuring sterility by providing devices which control the fluid flow in such ways that injection devices are isolated from each other, as well as from the source of sterile fluid, such as by use of selective valving devices and disposable dosing units.
摘要翻译：用于注射无菌液体的多个患者的装置和方法，同时通过提供以这样的方式控制流体流动的装置来确保无菌性，使得注射装置彼此分离，以及来自无菌流体源，例如通过使用选择性阀装置和一次性配量单元。

14. 发明授权

US08764621B2 Transcutaneous power transmission and communication for implanted heart assist and other devices 有权
标题翻译：用于植入心脏辅助和其他装置的经皮电力传输和通讯
公开(公告)号：US08764621B2
公开(公告)日：2014-07-01
申请号：US13546789
申请日：2012-07-11
申请人： Kurt D. Badstibner , Jonathan R. Speicher , Marlin S. Heilman , Richard A. Bates , Charles E. Greene
发明人： Kurt D. Badstibner , Jonathan R. Speicher , Marlin S. Heilman , Richard A. Bates , Charles E. Greene
IPC分类号： A61N1/362
CPC分类号： A61M1/1086 , A61M1/101 , A61M1/12 , A61M1/122 , A61M1/127 , A61M2205/3331 , A61M2205/3523 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/8206 , A61M2205/8243 , H01F38/14 , H02J5/005 , H02J7/025 , H02J50/12 , H02J50/80 , H02J50/90 , H04B5/0037 , H04B5/0062 , H04B5/0075
摘要： A system includes an implantable pump system for assisting blood flow in a patient including at least one movable valve. The movable valve is in a normally open state when the moveable valve is not being powered and a drive system in operative connection with the moveable valve to move the moveable valve under power. The system further includes an energy transfer system to provide energy to the drive system. The energy transfer system includes an external system including a power source and an external coil and an internal system including an internal coil adapted to receive transcutaneous energy transmitted from the external coil. The internal system has at least a first state wherein energy transmission from the external coil is required to provide operational power to the drive system.
摘要翻译：一种系统包括可植入泵系统，用于辅助包括至少一个活动阀在内的患者的血液流动。当可动阀未被供电时，可移动阀处于常开状态，以及与可移动阀操作连接的驱动系统以使可动阀在动力下移动。该系统还包括能量传递系统以向驱动系统提供能量。能量传递系统包括包括电源和外部线圈的外部系统以及包括适于接收从外部线圈传递的经皮能量的内部线圈的内部系统。内部系统具有至少第一状态，其中需要来自外部线圈的能量传输来向驱动系统提供操作功率。

15. 发明授权

US06761532B2 Touch down of blood pump impellers 失效
标题翻译：触碰血泵叶轮
公开(公告)号：US06761532B2
公开(公告)日：2004-07-13
申请号：US10097731
申请日：2002-03-14
申请人： Christopher D. Capone , Ruey C. Dempsey , Marlin S. Heilman , Steve A. Kolenik , Daniel R. Moore , Carl M. Parisi , Edward K. Prem , Richard A. Sofranko , David C. Borzelleca , Greg Burgreen , John A. Holmes , Zhongjun Wu , Ralph Scott Hebbert , James Antaki
发明人： Christopher D. Capone , Ruey C. Dempsey , Marlin S. Heilman , Steve A. Kolenik , Daniel R. Moore , Carl M. Parisi , Edward K. Prem , Richard A. Sofranko , David C. Borzelleca , Greg Burgreen , John A. Holmes , Zhongjun Wu , Ralph Scott Hebbert , James Antaki
IPC分类号： F04D700
CPC分类号： F04D29/047 , A61M1/101 , A61M1/1015 , A61M1/1017 , A61M1/1031 , A61M1/1086 , A61M1/122 , F04D13/064
摘要： A blood pump having rotor and/or stator touch down zones to prevent pump failure or hemolysis which can occur if the rotor comes into contact with the stator due to power failure or mechanical shock. The touch down zones can include forming, or coating, portions of adjacent surfaces of the stator and rotor which can come into contact if a rotor touch down occurs. The materials used to form or coat the touch down zones can have properties which ensure that no consequential damage to the contacting surfaces occurs.
摘要翻译：具有转子和/或定子的血泵触屏，以防止由于电源故障或机械冲击而导致转子与定子接触时可能发生泵故障或溶血。触碰区域可以包括形成或涂覆定子和转子的相邻表面的部分，如果发生转子触碰，则其可以接触。用于形成或涂覆触摸区域的材料可以具有确保不会对接触表面造成相应损害的性质。

16. 发明授权

US4270549A Method for implanting cardiac electrodes 失效
标题翻译：植入心脏电极的方法
公开(公告)号：US4270549A
公开(公告)日：1981-06-02
申请号：US34733
申请日：1979-04-30
申请人： Marlin S. Heilman
发明人： Marlin S. Heilman
IPC分类号： A61N1/05 , A61N1/04
CPC分类号： A61N1/0587
摘要： A method for implanting an electrode adjacent the heart of a patient without requiring major surgery. A skin incision is made in the anterior thoracic region and/or in the abdominal wall, and by means of a specialized implantation tool tunnels are created through which the electrodes may be inserted and placed in contact with the heart. The implantation tool cooperates with the electrode such that after placement of the electrode the tool may be withdrawn from the patient with the electrode remaining in place.
摘要翻译：一种将电极植入邻近患者心脏而不需要大手术的方法。在前胸区和/或腹壁中形成皮肤切口，并且通过专门的植入工具产生隧道，通过该隧道可以将电极插入并放置成与心脏接触。植入工具与电极配合使得在电极放置之后，工具可以在电极保持就位的情况下从病人身上取出。

17. 发明授权

US5383840A Biocompatible ventricular assist and arrhythmia control device including cardiac compression band-stay-pad assembly 失效
标题翻译：生物相容性心室辅助和心律失常控制装置，包括心脏压迫带 - 垫组件
公开(公告)号：US5383840A
公开(公告)日：1995-01-24
申请号：US920732
申请日：1992-07-28
申请人： Marlin S. Heilman , Steve A. Kolenik , Christopher D. Capone , Carl M. Parisi , Edward K. Prem , Vernon L. Speicher
发明人： Marlin S. Heilman , Steve A. Kolenik , Christopher D. Capone , Carl M. Parisi , Edward K. Prem , Vernon L. Speicher
IPC分类号： A61M1/10 , A61H31/00
CPC分类号： A61M1/1068 , A61M1/1046
摘要： A ventricular assist device for a heart includes a compression band-stay-pad assembly for encircling substantially the entire heart perimeter and comprising an elongated band member or chain disposed in a sealed protective structure filled with a lubricating medium. The band member may be fixed at one end and wound upon, or unwound from, a rotatable spool by a drive motor through a speed reducer. Force-transmitting support or stay assemblies are disposed in the protective structure between the band member and a resilient pad assembly for encircling the heart and promoting heart tissue ingrowth therein. The force-transmitting stay assemblies are biased circumferentially, and thus radially outward, by compression return springs disposed therebetween. The resilient pad assembly includes a corrugated surface provided with vertical coil springs, which help prevent damage to heart tissue and facilitate return of the pad assembly to an initial condition, embedded defibrillator electrodes and relatively soft portions to prevent damage to coronary arteries. The device may be constructed so that it can be surgically removed, except for a sealing film and an ingrown pad of the resilient pad assembly, which remain in situ on the heart. A net structure suspended below the device supports the apical portion of the heart.
摘要翻译：用于心脏的心室辅助装置包括用于围绕基本上整个心脏周边的压缩带状支架组件，并且包括设置在填充有润滑介质的密封保护结构中的细长带状构件或链条。带构件可以固定在一端，并通过驱动电动机通过减速器缠绕在可旋转的卷轴上或从其释放。力传递支撑件或支撑组件设置在带构件和弹性垫组件之间的保护结构中，用于环绕心脏并促进其中的心脏组织向内生长。力传递支柱组件通过设置在它们之间的压缩复位弹簧周向地偏置，并因此被径向向外偏压。弹性垫组件包括具有垂直螺旋弹簧的波纹表面，其有助于防止对心脏组织的损伤并且便于将垫组件返回到初始状态，嵌入的除颤器电极和相对较软的部分以防止损伤冠状动脉。除了保留在心脏上的弹性垫组件的密封膜和内衬垫之外，该装置可被构造成能够手术除去。悬挂在装置下面的网状结构支撑心脏的顶端部分。

18. 发明授权

US5098369A Biocompatible ventricular assist and arrhythmia control device including cardiac compression pad and compression assembly 失效
标题翻译：生物相容性心室辅助和心律失常控制装置，包括心脏压缩垫和压缩组件
公开(公告)号：US5098369A
公开(公告)日：1992-03-24
申请号：US522956
申请日：1990-05-14
申请人： Marlin S. Heilman , Steve A. Kolenik , Christopher D. Capone , Carl M. Parisi , Edward K. Prem , Vernon L. Speicher
发明人： Marlin S. Heilman , Steve A. Kolenik , Christopher D. Capone , Carl M. Parisi , Edward K. Prem , Vernon L. Speicher
IPC分类号： A61M1/10 , A61M1/12 , A61N1/362
CPC分类号： A61M1/1068 , A61M1/1046 , A61M1/127 , A61N1/3627
摘要： A ventricular assist device may include a cardiac compression assembly which comprises a gel-filled pad of generally concave configuration, mounted on a pressure plate with peripheral portions of the pad extending beyond the periphery of the plate, to preclude damage to the heart by the peripheral edges of the plate. The gel-filled pad may have undulating opposite sides formed by intersecting rows of raised dimples. The pad also includes portions for suturing the pad to a heart ventricle, and at least some of the dimples on the side of the pad facing the heart ventricle are provided with ventricle tissue growth-promoting islands. An electrode, in the form of a grid having intersecting strips which define dimple-receiving openings therebetween, also may be mounted on the venticle side of the pad. As many as eight circumferentially arranged cardiac compression assemblies, having lower ends pivotally mounted on a support member adapted to be located adjacent the apex of a heart ventricle, may be provided. Operating systems for operating the cardiac compression assemblies may include a motor-driven camming mechanism; a mechanism comprising a device for converting electrical energy to hydraulic fluid energy, two sealed fluid systems, a reversible pump, two bellows and a safety solenoid pump-bypass fluid return valve; or a closed loop system comprising a reversible pump in a fluid supply casing, a hydraulic fluid manifold including a plurality of miniature fluid actuators which may be of arcuate construction to conserve space, and a mechanism for collecting fluid leaking from the actuators and returning it to the fluid supply casing.
摘要翻译：心室辅助装置可以包括心脏压缩组件，该心脏压缩组件包括一个大致凹形构型的凝胶填充垫，安装在压板上，垫的周边部分延伸超过板的周边，以排除周边的心脏损伤板的边缘。凝胶填充的垫可以具有由凸起的凹坑的相交行形成的起伏的相对侧。衬垫还包括用于将垫缝合到心室的部分，并且面向心室的衬垫侧面上的至少一些凹窝设置有心室组织生长促进岛。具有在其间限定凹坑接收开口的相交条带的网格形式的电极也可以安装在垫的通气面上。可以提供多达八个周向布置的心脏压缩组件，其具有可枢转地安装在适于邻近心脏心尖的位置定位的支撑构件上的下端。用于操作心脏压缩组件的操作系统可以包括马达驱动的凸轮机构; 包括用于将电能转换成液压流体能量的装置的机构，两个密封流体系统，可逆泵，两个波纹管和安全螺线管泵旁通流体回流阀; 或包括流体供应壳体中的可逆泵的闭环系统，包括可以具有弓形结构以节省空间的多个微型流体致动器的液压流体歧管以及用于收集从致动器泄漏的流体并将其返回到流体供应套管。

19. 发明授权

US4080706A Method of manufacturing catheter guidewire 失效
标题翻译：制造导管导丝的方法
公开(公告)号：US4080706A
公开(公告)日：1978-03-28
申请号：US739016
申请日：1976-11-04
申请人： Marlin S. Heilman , Seid W. Waddell
发明人： Marlin S. Heilman , Seid W. Waddell
IPC分类号： A61M25/00 , A61M25/09 , B23P13/00 , B21F35/00
CPC分类号： C25F3/00 , A61M25/09 , A61M25/09033 , B23P13/00 , A61M2025/09075 , A61M2025/09083 , A61M2025/09108 , Y10T29/49
摘要： There is disclosed a catheter guidewire and a method for manufacturing the guidewire. In one embodiment, the guidewire is developed from a coiled semi-rectangular flatwire which has been coated with a surface lubricant such as Teflon prior to winding. In another embodiment, the flatwire is wound, polished by abrasion and then electropolished. A combination safety core wire extends longitudinally within the coiled guidewire and is welded to the respective ends of the guidewire. The safety core wire is a cylindrical wire whose uniform main body is smoothly tapered into an ultra-flexible flattened distal tip by means of combined mechanical metal forming and electro-etching techniques.
摘要翻译：公开了一种导管导丝及其制造方法。在一个实施例中，导丝从卷绕的半矩形扁平线显影，其在卷绕之前已经涂覆有表面润滑剂（例如特氟隆）。在另一个实施例中，扁丝被磨损，磨光抛光，然后进行电抛光。组合安全芯线在线圈导丝内纵向延伸并焊接到导丝的相应末端。安全芯线是通过组合的机械金属成形和电蚀刻技术将均匀的主体平滑地锥形成超柔性扁平末端的圆柱形线。

20. 发明授权

US4928690A Portable device for sensing cardiac function and automatically delivering electrical therapy 失效
标题翻译：用于感应心脏功能和自动递送电疗的便携式设备
公开(公告)号：US4928690A
公开(公告)日：1990-05-29
申请号：US185781
申请日：1988-04-25
申请人： Marlin S. Heilman , Arlan J. Brandt , Larry D. Bowling , Joseph F. Russial
发明人： Marlin S. Heilman , Arlan J. Brandt , Larry D. Bowling , Joseph F. Russial
IPC分类号： A61N1/365 , A61B5/00 , A61N1/04 , A61N1/08 , A61N1/39
CPC分类号： A61B5/6831 , A61N1/39 , A61B5/0006 , A61N2001/083
摘要： A patient-worn harness or vest protects at-risk patients from the possibly fatal results of heart arrhythmias. The harness or vest incorporates sensing electrodes for monitoring heart condition, a microprocessor and memory for processing signals received from the sending electrodes and comparing same with patient's data, and skin-contacting pulsing electrodes for applying electrical pulses to the patient's chest wall responsive to signals received from the microprocessor. The electrodes include automatic tightening and electrolyte gel release mechanisms for reducing impedance at the electrode-skin interface. A servicing subsystem is provided for the harness or vest and may be used to interface with the harness or vest and also to communicate with remote health care personnel through a suitable telephone link.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式