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    • 14. 发明申请
    • Methods and Systems for Sampling Heavy Oil Reservoirs
    • 重油藏采样方法与系统
    • US20080135239A1
    • 2008-06-12
    • US11609402
    • 2006-12-12
    • John Edwards
    • John Edwards
    • E21B49/08
    • E21B49/081E21B49/084
    • Methods and systems and are described for isolating or manipulating a sample of a heavy oil composition from a hydrocarbon reservoir. One method embodiment of the invention comprises circulating a heated fluid in a first region of a reservoir where a heavy oil composition is present or believed present using a surface pump and a well completion comprising a downhole pump for a time and flow rate sufficient to produce flowable heavy oil composition, the well completion comprising a sampling tool; and sampling the flowable heavy oil composition using the sampling tool. This abstract complies with rules requiring an abstract. It should not be used to limit the scope or meaning of the claims. 37 CFR 1.72(b).
    • 描述了用于从烃储存器中分离或操纵重油组合物的样品的方法和系统。 本发明的一个方法实施方案包括在储存器的第一区域中循环加热的流体,其中存在或认为存在的重油组合物使用表面泵和包括井下泵的井完井,其时间和流速足以产生可流动的 重油组成,完井完成包括采样工具; 并使用采样工具对可流动的重油组合物进行取样。 本摘要符合要求摘要的规则。 它不应用于限制权利要求的范围或含义。 37 CFR 1.72(b)。
    • 15. 发明授权
    • Space allocation in a write anywhere file system
    • 空间分配在写任意文件系统
    • US07290013B2
    • 2007-10-30
    • US10688070
    • 2003-10-17
    • Douglas P. DoucetteBlake LewisJohn Edwards
    • Douglas P. DoucetteBlake LewisJohn Edwards
    • G06F17/30G06F17/00
    • G06F3/0605G06F3/0608G06F3/0631G06F3/0643G06F3/0644G06F3/0689G06F17/30067Y10S707/99943Y10S707/99952Y10S707/99953Y10S707/99956
    • The invention provides a method and system for improving data access of a reliable file system. In a first aspect of the invention, the file system determines the relative vacancy of a collection of storage blocks, herein called an “allocation area”. This is accomplished by recording an array of binary numbers. Each binary number in the array describes the vacancy of a collection of storage blocks. The file system examines these binary numbers when attempting to record file blocks in relatively contiguous areas on a storage medium, such as a hard disk. When a request to write to disk occurs, the system determines the average vacancy of all the allocation areas and queries the allocation areas for individual vacancy rates such as sequentially. The system preferably writes file blocks to the allocation areas that are above a threshold related to the average storage block vacancy of the file system. If the file in the request to write is larger than the selected allocation area, the next allocation area above the threshold is preferably used to write the remaining blocks of the file.
    • 本发明提供了一种用于改善可靠文件系统的数据访问的方法和系统。 在本发明的第一方面,文件系统确定存储块集合的相对空位,这里称为“分配区域”。 这是通过记录二进制数字的数组来实现的。 阵列中的每个二进制数字描述了存储块集合的空位。 当尝试在诸如硬盘的存储介质上的相对连续的区域中记录文件块时,文件系统检查这些二进制数。 当写入磁盘的请求发生时,系统确定所有分配区域的平均空缺,并查询单个空缺率的分配区域,如顺序。 系统优选地将文件块写入高于与文件系统的平均存储块空缺相关的阈值的分配区域。 如果写入请求中的文件大于所选择的分配区域,则优选地使用高于阈值的下一个分配区域来写入文件的剩余块。
    • 17. 发明申请
    • Pharmaceutical compositions and methods to vaccinate against disseminated candidiasis and other infectious agents
    • 用于接种弥撒念珠菌病和其他感染因子的药物组合物和方法
    • US20070077256A1
    • 2007-04-05
    • US11327197
    • 2006-01-06
    • John EdwardsAshraf IbrahimBrad SpellbergYue FuScott FillerMichael Yeaman
    • John EdwardsAshraf IbrahimBrad SpellbergYue FuScott FillerMichael Yeaman
    • A61K39/02
    • A61K39/0002A61K39/085A61K2039/5156A61K2039/58C07K16/14C07K2317/76
    • The invention provides a vaccine including an isolated Als protein family member having cell adhesion activity, or an immunogenic fragment thereof, with an adjuvant in a pharmaceutically acceptable medium. The invention also provides a method of treating or preventing hematogenously disseminated or mucocutaneous candidiasis. The method includes administering an immunogenic amount of a vaccine an isolated Als protein family member having cell adhesion activity, or an immunogenic fragment thereof, in a pharmaceutically acceptable medium. A method of treating or preventing disseminated candidiasis also is provided that includes administering an effective amount of an isolated Als protein family member having cell adhesion activity, or an functional fragment thereof, to inhibit the binding or invasion of Candida to a host cell or tissue. The Als protein family member can be derived from a Candida strain selected from the group consisting of Candida albicans, Candida krusei, Candida tropicalis, Candida glabrata and Candida parapsilosis and the Als protein family member includes Als1p, Als3p, Als5p, Als6p, Als7p or Als9p. Also provided is a method of treating or preventing Staphylococcus aureus infections. The method includes administering an immunogenic amount of a vaccine an isolated Als protein family member having cell adhesion activity, or an immunogenic fragment thereof, in a pharmaceutically acceptable medium.
    • 本发明提供了包含具有细胞粘附活性的分离的Als蛋白家族成员或其免疫原性片段的疫苗,其在药学上可接受的培养基中与佐剂一起使用。 本发明还提供了治疗或预防血液弥漫性或粘膜皮肤念珠菌病的方法。 该方法包括在药学上可接受的培养基中施用免疫原性量的具有细胞粘附活性的分离的Als蛋白家族成员或其免疫原性片段的疫苗。 还提供了治疗或预防弥漫性念珠菌病的方法,其包括施用有效量的具有细胞粘附活性的分离的Als蛋白家族成员或其功能片段,以抑制念珠菌与宿主细胞或组织的结合或侵入。 Als蛋白家族成员可以衍生自选自白色念珠菌,克罗斯假丝酵母,热带假丝酵母,光滑假丝酵母和副假丝酵母的念珠菌菌株,Als蛋白家族成员包括Als1p,Als3p,Als5p,Als6p,Als7p或Als9p 。 还提供了治疗或预防金黄色葡萄球菌感染的方法。 该方法包括在药学上可接受的培养基中施用免疫原性量的具有细胞粘附活性的分离的Als蛋白家族成员或其免疫原性片段的疫苗。
    • 20. 发明申请
    • File folding technique
    • 文件折叠技术
    • US20060168409A1
    • 2006-07-27
    • US11393543
    • 2006-03-28
    • Andy KahnKayuri PatelRaymond ChenJohn Edwards
    • Andy KahnKayuri PatelRaymond ChenJohn Edwards
    • G06F12/00G06F12/14
    • G06F17/3015Y10S707/99931Y10S707/99942Y10S707/99952Y10S707/99953
    • A method for reducing duplicate data of an active file system, where the data is stored on a storage device of a storage system, is disclosed. A persistent image of the active file system is generated at a first point in time. At a later time, a sequence of steps to compare the active file system with the persistent image is initiated. Then, if a block of data of the active file system is identical to the data in the persistent image, the active file system is directed to refer to the persistent image for data of the file. Alternatively, if the block of data of the active file system is not identical to the data in the persistent image, the active file system is directed to refer to the data of the active file system. A file folding command may be issued to start the comparison.
    • 公开了一种用于减少存储在存储系统的存储设备上的活动文件系统的重复数据的方法。 在第一时间点生成活动文件系统的持久图像。 稍后,启动将活动文件系统与持久性映像进行比较的一系列步骤。 然后,如果活动文件系统的数据块与持久性图像中的数据相同,则活动文件系统被引导以引用文件数据的持久图像。 或者,如果活动文件系统的数据块与持久图像中的数据不相同,则活动文件系统被引导以参考活动文件系统的数据。 可以发出文件折叠命令来开始比较。