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    • 16. 发明授权
    • Hydrophilic polymer blends used for dry cow therapy
    • 用于干牛治疗的亲水性聚合物混合物
    • US06440442B1
    • 2002-08-27
    • US09706677
    • 2000-11-06
    • Joseph EhrhardMichael EknoianAlfredo Vinci
    • Joseph EhrhardMichael EknoianAlfredo Vinci
    • A01N2524
    • A01N31/16A01N25/24A01N35/08A01N47/44A01N59/12A61K9/0041A61K9/7015A61K31/047A61K31/09A61K31/155A61K33/18A01N2300/00
    • The present invention provides a mammalian teat dip composition capable of being used during a mammal's dry period comprising a solution of a film-forming polymer blend comprising a first polymer component which is an organic, solvent-soluble, preformed, thermoplastic polyurethane having no reactive isocyanate groups and a second polymer component which is a hydrophilic poly(N-vinyl lactam), said blend capable of withstanding exposure to water without significant loss of said hydrophilic poly(N-vinyl lactam) in an amount sufficient to form a water-resistant film upon topical application to mammalian skin; and wherein said blend comprises from about 10 to about 80 weight percent of said first polymer in combination with said solvent and from about 1 to about 20 weight percent of said second polymer; and at least one antimicrobial agent in an amount sufficient to treat and protect mammalian skin from infection; wherein said composition is capable of being removed by peeling.
    • 本发明提供一种能够在哺乳动物的干燥期间使用的哺乳动物乳头浸渍组合物,其包含成膜聚合物共混物的溶液,该共混物包含第一聚合物组分,其是具有无反应性异氰酸酯的有机溶剂可溶性预成型热塑性聚氨酯 基团和第二聚合物组分,其是亲水性聚(N-乙烯基内酰胺),所述共混物能够耐受暴露于水,而不会显着损失所述亲水性聚(N-乙烯基内酰胺),其量足以形成耐水膜 局部应用于哺乳动物皮肤; 并且其中所述共混物包含约10至约80重量%的所述第一聚合物与所述溶剂和约1至约20重量%的所述第二聚合物; 和至少一种抗微生物剂,其量足以治疗和保护哺乳动物皮肤免受感染; 其中所述组合物能够通过剥离除去。