专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

US08075573B2 Single intubation, multi-stitch endoscopic suturing system 有权
标题翻译：单插管，多针内窥镜缝合系统
公开(公告)号：US08075573B2
公开(公告)日：2011-12-13
申请号：US10847190
申请日：2004-05-17
申请人： Richard A. Gambale , Peter J. Lukin , Paul C. DiCesare , Christopher A. Battles , Jeffrey P. Radziunas , Danial P. Ferreira
发明人： Richard A. Gambale , Peter J. Lukin , Paul C. DiCesare , Christopher A. Battles , Jeffrey P. Radziunas , Danial P. Ferreira
IPC分类号： A61B17/04 , A61B17/12
CPC分类号： A61B17/0469 , A61B17/0467 , A61B17/0487 , A61B2017/00827 , A61B2017/045 , A61B2017/0464 , A61B2017/047
摘要： Provided is an endoscopic suturing system for joining internal body tissues in a variety of procedures. The system comprises a suturing capsule releasably mountable to the distal end of an endoscope and capable of forming multiple stitches in tissue at a plurality of locations without requiring withdrawal of the capsule from the patient between stitches. Also enclosed is a suture lock to secure the placed stitch that is delivered by a device introduced through the working channel of the indwelling endoscope. Suitable control handles for the suturing capsule and for the suture lock delivery device positioned at the proximal end of the endoscope are provided to facilitate operation by the user.
摘要翻译：提供了一种用于以各种方法连接内部身体组织的内窥镜缝合系统。该系统包括可释放地安装到内窥镜的远端的缝合胶囊，并且能够在多个位置处在组织中形成多个线圈，而不需要在线圈之间从患者中取出胶囊。还包括缝合线锁，用于固定由通过留置内窥镜的工作通道引入的装置输送的放置针迹。提供用于缝合胶囊和位于内窥镜的近端处的缝线锁输送装置的合适的控制手柄，以便于使用者的操作。

12. 发明授权

US08992570B2 Suture clips, delivery devices and methods 有权
标题翻译：缝合夹，输送装置和方法
公开(公告)号：US08992570B2
公开(公告)日：2015-03-31
申请号：US11604944
申请日：2006-11-28
申请人： Richard A. Gambale , Michael F. Weiser , Edward Carlton Page , Alexander Kolnick
发明人： Richard A. Gambale , Michael F. Weiser , Edward Carlton Page , Alexander Kolnick
IPC分类号： A61B17/04
CPC分类号： A61B17/0487 , A61B17/0467 , A61B17/0469 , A61B2017/0417 , A61B2017/0424 , A61B2017/0445 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0459 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , Y10T24/3969
摘要： Suture clips and suture clip loading, delivery, locking and severing devices in both catheter and endoscopic embodiments are disclosed that permit the delivery and application of suture clips directly in contact with or in close approximation to sutured tissue. The catheter or endoscopic versions incorporate a collet cage with a plurality of flexible collet fingers that captivate a suture clip ring and a suture clip plug for assembly with a suture. An outer sliding sleeve constrains the collet fingers when distally advanced to minimize potential trauma during delivery and assembly of the suture clip in close proximity to the stitched tissue. Proximal retraction of the sliding sleeve coupled with the distal advancement of a pusher against cam surfaces on the inner walls of the collet fingers causes the collet fingers to open. The catheter is designed to hold and assemble the suture clip in a first position and release the suture clip and sever the suture ends proximal to the suture clip in a second position. Single pusher two-step embodiments and double pusher three-step embodiments are disclosed. Suture clip designs with plugs having heads for use with the suture clip delivery catheter are also disclosed. A suture clip loading device for loading suture clip components into the delivery system as well as a threader for threading sutures into the suture clip systems are also disclosed. A method of loading, delivering and deploying suture clips is further disclosed.
摘要翻译：公开了导管和内窥镜实施例中的缝合夹和缝合夹装载，递送，锁定和切断装置，其允许缝合夹直接与缝合组织接触或接近近似地递送和施加。导管或内窥镜版本包括具有多个柔性夹头的夹头保持器，其夹持缝合夹环和缝合夹塞以与缝合线组装。外滑动套筒在向远侧前进时约束夹头，以最小化缝合夹在紧靠缝合组织的递送和组装期间的潜在创伤。与推动器的远端前进部联接的滑动套筒的近端缩回抵靠夹头指状物的内壁上的凸轮表面使得夹头指状物打开。导管被设计成将缝合夹保持并组装在第一位置，并释放缝合夹并在第二位置将缝合线端部切割成缝合线夹。公开了单推杆两步实施例和双推动器三步实施例。还公开了具有插头的缝合夹设计，其具有用于缝合夹输送导管的头部。还公开了一种用于将缝合夹组件加载到输送系统中的缝线夹装载装置以及用于将缝线穿入缝合夹系统的穿线器。进一步公开了一种加载，递送和部署缝合夹的方法。

13. 发明授权

US07996993B2 Temporary vascular filter guide wire 失效
标题翻译：临时血管过滤器导丝
公开(公告)号：US07996993B2
公开(公告)日：2011-08-16
申请号：US11699878
申请日：2007-01-30
申请人： William Gray , Richard A. Gambale
发明人： William Gray , Richard A. Gambale
IPC分类号： B23P15/16
CPC分类号： A61F2/01 , A61F2/013 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/0021 , A61F2230/005 , A61F2230/0067 , A61F2230/0086 , A61F2230/0093 , A61F2230/0097 , A61M25/09 , A61M2025/09183 , Y10T29/49604 , Y10T29/49801
摘要： A method of making a filter is disclosed including providing a mandrel, positioning a filter form on the mandrel, the filter form including a dissolvable compound, disposing a filter basket over the filter form, dissolving the filter form, and removing the mandrel from the filter basket.
摘要翻译：公开了一种制造过滤器的方法，包括提供心轴，将过滤器形状定位在心轴上，过滤器形式包括可溶解化合物，将过滤篮设置在过滤器形式上，溶解过滤器形式，以及从过滤器中移出心轴篮。

14. 发明授权

US06692520B1 Systems and methods for imbedded intramuscular implants 失效
标题翻译：嵌入肌内植入物的系统和方法
公开(公告)号：US06692520B1
公开(公告)日：2004-02-17
申请号：US09211332
申请日：1998-12-15
申请人： Richard A. Gambale , Mike Weiser , Stephen Forcucci , Chirag B. Shah
发明人： Richard A. Gambale , Mike Weiser , Stephen Forcucci , Chirag B. Shah
IPC分类号： A61F206
CPC分类号： A61F2/2493 , A61F2/02 , A61F2/064
摘要： The invention includes systems and methods for stimulating intramuscular angiogenesis by placing a biocompatible device within the tissue of a muscle. The biocompatible device is dimensionally adapted for placement within the tissue of a muscle. Placement of the biocompatible device within the muscle can take place according to the method of the invention by using techniques familiar to those of ordinary skill in the art. Illustrative techniques for placement of the device within the myocardium comprise one practice of the method of the invention.
摘要翻译：本发明包括通过将生物相容性装置放置在肌肉组织内来刺激肌肉内血管发生的系统和方法。生物相容性装置在尺寸上适于放置在肌肉组织内。通过使用本领域普通技术人员熟悉的技术，可以根据本发明的方法将生物相容性装置置于肌肉内。用于将装置放置在心肌内的说明性技术包括本发明方法的一个实践。

15. 发明授权

US07220266B2 Tissue capturing and suturing device and method 有权
标题翻译：组织捕获和缝合装置及方法
公开(公告)号：US07220266B2
公开(公告)日：2007-05-22
申请号：US10275534
申请日：2001-05-19
申请人： Richard A. Gambale
发明人： Richard A. Gambale
IPC分类号： A61B17/04 , A61B17/10 , A61B19/00
CPC分类号： A61B17/0469 , A61B17/0401 , A61B17/0482 , A61B17/0487 , A61B2017/0409 , A61B2017/0417 , A61B2017/0454 , A61B2017/0474 , A61B2017/0475 , A61B2017/0488 , A61B2017/06052 , A61B2017/306
摘要： A combination tissue apposition and suture capturing device (100) for performing endoscopic procedures typically in the gastro-esophageal tract. The device (100) is particularly adapted for forming multiple plications used in a gastroplasty procedure devised to cure or ameliorate gastro-esophageal reflux disease. The device includes a tissue sewing capsule (102) attached to the distal end of an endoscope having a needle (120) that is deposited in a capsule (102) distal tip cavity following the suturing of a tissue fold and retrieved to enable the suturing of a subsequent tissue fold without the need for multiple intubations. A suture clip delivery device (200) is also disclosed that is adapted to fit within the capsule (102) to enable suture (118) capture without the need for multiple intubations. The combination device eliminates the need for an overtube and maximizes the speed efficiency of the gastroplasty procedure. A method for using the combination device is also disclosed.
摘要翻译：一种用于通常在胃食管道内执行内窥镜手术的组合组合装置和缝合线捕获装置（100）。装置（100）特别适于形成用于治愈或改善胃食管反流疾病的胃成形术程序中使用的多种不适。该装置包括附着到内窥镜的远端的组织缝合胶囊（102），该内窥镜具有在缝合组织折叠之后沉积在胶囊（102）远侧末端腔中的针头（120），并且被检索以使缝合随后的组织折叠而不需要多个插管。还公开了缝线夹输送装置（200），其适于装配在胶囊（102）内以使得能够缝合（118）捕获而不需要多次插管。组合装置消除了对外套管的需要并使胃成形术程序的速度效率最大化。还公开了一种使用组合装置的方法。

16. 发明授权

US06629987B1 Catheter positioning systems 失效
标题翻译：导管定位系统
公开(公告)号：US06629987B1
公开(公告)日：2003-10-07
申请号：US09364520
申请日：1999-07-30
申请人： Richard A. Gambale , Stephen J. Forcucci , Chirag B. Shah , Michael F. Weiser , Sean Forde
发明人： Richard A. Gambale , Stephen J. Forcucci , Chirag B. Shah , Michael F. Weiser , Sean Forde
IPC分类号： A61M2900
CPC分类号： A61M25/04 , A61B2017/3488 , A61M25/0084 , A61M2025/0087
摘要： The present invention provides a catheter positioning system which serves to control and stabilize a distal end of a catheter at a treatment site within a patient so that a medical procedure can be performed with accuracy. Generally, the positioning system operates by providing a deformable mechanical members at the distal end of the catheter which can be operated from the proximal end of the catheter to extend radially outward to engage surrounding tissue adjacent to treatment site. In one embodiment of the invention a flexible superstructure comprising the plurality of flexible veins extending longitudinally along the distal end of the catheter can be deformed to bow radially outward to engage surrounding tissue. The distal tip of the catheter joined to one of the veins was correspondingly displaced or rotated angularly as the veins bow outward. In another embodiment radially projecting fingers are joined to the distal end of the catheter, which remain retracted during navigation of the catheter to the treatment site then are extended outward to penetrate the tissue and secure the catheter at the treatment site upon being actuated from the proximal end of the catheter by a physician. Methods of positioning a catheter are also disclosed. The inventive device and method are particularly useful in catheter based procedures carried out in large body lumens or in cavities of body organs. In particular, the invention may be useful in delivering implants percutaneously through the left ventricle into the myocardium of the heart.
摘要翻译：本发明提供了一种导管定位系统，其用于控制和稳定患者内的治疗部位处的导管的远端，使得可以精确地执行医疗程序。通常，定位系统通过在导管的远端处提供可变形的机械构件来操作，该可变形机械构件可以从导管的近端操作以径向向外延伸以接合邻近治疗部位的周围组织。在本发明的一个实施例中，包括沿着导管的远端纵向延伸的多个柔性静脉的柔性上部结构可以变形以径向向外弯曲以接合周围的组织。当静脉向外弯曲时，连接到静脉中的一个静脉的导管的远端相应地位移或旋转。在另一个实施例中，径向突出的指状物连接到导管的远端，导管的远端在导管导航到治疗部位期间保持缩回，然后向外延伸以穿透组织，并且在从近端致动时将导管固定在治疗部位导管的末端由医师。还公开了定位导管的方法。本发明的装置和方法特别适用于在大体腔或身体器官腔中进行的基于导管的程序。特别地，本发明可用于将植入物通过左心室经皮穿入心脏心肌。

17. 发明授权

US06331185B1 Flexible vascular inducing implants 失效
公开(公告)号：US06331185B1
公开(公告)日：2001-12-18
申请号：US09164163
申请日：1998-09-30
申请人： Richard A. Gambale , Stephen J. Forcucci , Michael F. Weiser , Richard T. Choh , Sean Forde
发明人： Richard A. Gambale , Stephen J. Forcucci , Michael F. Weiser , Richard T. Choh , Sean Forde
IPC分类号： A61F206
摘要： Implants and associated delivery systems for promoting angiogenesis in ischemic tissue are provided. The implants may be delivered percutaneously, thoracically or surgically and are particularly well suited for implantation into the myocardium of the heart. The implants are configured to be flexible so that they compress and expand with corresponding movement of the surrounding tissue into which they are implanted. The flow of blood into the implant and pooling of the blood in and around the implant leads to thrombosis and fibrin growth, a healing process that leads to angiogenesis in the tissue surrounding the implant. Additionally, the implants may contain an angiogenic substance or a thrombus of blood, preloaded or injected after implantation to aid in initiating angiogenesis.

18. 发明授权

US06231564B1 Storable guidewire system 失效
标题翻译：可存储的导丝系统
公开(公告)号：US06231564B1
公开(公告)日：2001-05-15
申请号：US08536954
申请日：1995-09-29
申请人： Richard A. Gambale
发明人： Richard A. Gambale
IPC分类号： A61M2501
CPC分类号： A61M25/104 , A61M25/0113 , A61M25/09041
摘要： A method and apparatus are provided for releasably storing the additional exchange length of a medical guidewire within a housing, in a compacted configuration until it is needed by the physician to perform a catheter exchange. This guidewire has a distal portion which is similar to a traditional guidewire in length and construction and is used throughout the catheterization procedure much like a conventional guidewire. A proximal portion of the guidewire provides added length to effect a catheter exchange in the manner of a conventional exchange wire but may be tightly compacted and stored out of the way within a storage receptacle until the moment that the added length is needed for an exchange. The storage receptacle enables the physician to utilize the distal portion of the guidewire wire much like a conventional guidewire, then release the proximal portion quickly to effect a catheter exchange. The readily available additional length of wire offers the physician all the advantages of a traditional exchange wire while avoiding the handling problems associated with an uncontained exchange length that is unneeded during much of the procedure. The guidewire wire containment system of the present invention simplifies catheterization procedures by enabling the physician to maintain wire position during an exchange while keeping the exchange length of wire conveniently contained until it is needed to complete the procedure.
摘要翻译：提供了一种方法和装置，用于将医疗导线的附加交换长度可释放地存储在壳体内，处于压缩构型，直到医师需要进行导管交换。该导丝具有远端部分，其长度和结构类似于传统的导丝，并且在整个导管插入过程中使用得非常像传统的导丝。导线的近端部分以常规交换线的方式提供增加的长度以实现导管交换，但是可以紧紧地压实并存储在存储容器内，直到交换所需的增加长度的时刻。存储容器使得医生能够像传统的导丝一样利用导丝线的远端部分，然后快速地释放近端部分以实现导管交换。随时可用的额外长度的电线为医生提供传统交换线的所有优点，同时避免了在大部分过程中不需要的不受限制的交换长度的处理问题。本发明的导丝线收容系统通过使医师在交换期间保持线位置而简化了导管插入程序，同时保持线的交换长度方便地包含直到需要完成该过程。

19. 发明授权

US5031636A Guide wire extension 失效
标题翻译：导线延伸
公开(公告)号：US5031636A
公开(公告)日：1991-07-16
申请号：US458908
申请日：1989-12-29
申请人： Richard A. Gambale , James F. Crittenden , James P. Ryan
发明人： Richard A. Gambale , James F. Crittenden , James P. Ryan
IPC分类号： A61M25/01 , B21F15/06
CPC分类号： A61M25/0169 , A61M25/0905 , B21F15/06 , A61M25/09041
摘要： A guide wire system for use in catheter exchanges avoids the need for a separate exchange wire. Instead of the conventional practice in which the initial guide wire is removed and replaced with a longer exchange wire, a guide wire extension is attached to the proximal end of the initial guide wire thereby increasing its effective length so that it may be used to perform a catheter exchange. The initial guide wire remains in place in the patient's vasculature. The proximal end of the guide wire and the distal end of the exchange wire are formed to define a connection which may be crimped to effect the connection between the two wires. A crimping tool is provided to hold the mating ends of the guide wire and extension wire together while effecting the crimp.
摘要翻译：用于导管交换的引导线系统避免了对单独的交换线的需要。替代常规做法，其中移除初始导丝并用较长的交换线代替，导线延伸部附接到初始导丝的近端，从而增加其有效长度，使得其可用于执行导管交换。初始导丝保留在患者的脉管系统中。引导线的近端和交换线的远端形成为限定可以被压接以实现两条线之间的连接的连接。提供压接工具以将导丝和延长线的配合端保持在一起，同时实现卷曲。

20. 发明授权

US07862577B2 Temporary vascular filter guide wire 有权
标题翻译：临时血管过滤器导丝
公开(公告)号：US07862577B2
公开(公告)日：2011-01-04
申请号：US10255232
申请日：2002-09-25
申请人： William Gray , Richard A. Gambale
发明人： William Gray , Richard A. Gambale
IPC分类号： A61F2/01
CPC分类号： A61F2/01 , A61F2/013 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/0021 , A61F2230/005 , A61F2230/0067 , A61F2230/0086 , A61F2230/0093 , A61F2230/0097 , A61M25/09 , A61M2025/09183 , Y10T29/49604 , Y10T29/49801
摘要： A temporary filter is described for use in percutaneous intravascular procedures for the treatment of diseased blood vessels, such as angioplasty or stent placement procedures. The guide wire which is used to direct a catheter (such as a balloon catheter) to a treatment site contains a deployable filter. The guide wire is moveable independently of the catheter and can be used to position the filter at a desired location downstream of the treatment site. The guide wire includes parts moveable with respect to each other and the filter is connected to these parts in such a way that it can be deployed and collapsed by relative movement of the parts.
摘要翻译：描述了用于经皮血管内手术治疗患病血管的临时过滤器，例如血管成形术或支架置入程序。用于将导管（例如气囊导管）引导到治疗部位的引导线包含可部署的过滤器。引导线可以独立于导管移动，并且可以用于将过滤器定位在治疗部位下游的期望位置处。引导线包括可相对于彼此移动的部件，并且过滤器以这样的方式连接，使得其可以通过部件的相对移动来展开和折叠。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式