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11. 发明申请

US20070073271A1 Catheter for diagnostic imaging and therapeutic procedures 审中-公开
标题翻译：导管用于诊断成像和治疗程序
公开(公告)号：US20070073271A1
公开(公告)日：2007-03-29
申请号：US10575318
申请日：2004-11-15
申请人： Gregory Brucker , Steven Savage , John Gardner , Frederick Trombley, III
发明人： Gregory Brucker , Steven Savage , John Gardner , Frederick Trombley, III
IPC分类号： A61M25/16 , A61M25/18
CPC分类号： A61M25/0041 , A61M25/0043 , A61M25/0068 , A61M25/0069 , A61M25/007 , A61M25/0074 , A61M25/008 , A61M25/01 , A61M2025/0057 , A61M2025/0073 , A61M2025/0076
摘要： A catheter for use in introducing fluid into a vessel or other bodily structure. The catheter comprises a stem and a restrictor. The stem has approximate a distal end thereof a porous section that defines microholes distributed thereabout, which are inclined by a predetermined angle in the proximal direction. Affixed to the stem, the restrictor includes a conically-shaped valve with an apex thereof defining an opening and pointing in the proximal direction. The opening generally decreases in size as the conically-shaped valve flattens out distally as the pressure of the fluid within the tip increases. The forces of the fluid flowing out of the opening of the restrictor and out of the microholes of the stem substantially balance thereby substantially eliminating both recoil and whipping of the catheter, thus enabling its position to remain exceptionally stable while the fluid is finely dispersed therefrom in a cloud-like form.
摘要翻译：用于将流体引入血管或其他身体结构中的导管。导管包括杆和限流器。杆具有近端的远端，多孔部分限定分布在其周围的微孔，其沿近端方向倾斜预定角度。限流器被固定在杆上，该限流器包括一个圆锥形的阀，其顶点限定开口并指向近端方向。当锥形阀门在尖端内的流体的压力增加时，锥形阀门向远侧平坦化，开口的尺寸通常减小。从限流器的开口流出并离开杆的微孔的流体的力基本上平衡，从而基本上消除了导管的反冲和鞭打，从而使得其位置在流体从其中细分散而保持非常稳定的状态一个云状的形式。

12. 发明申请

US20050143721A1 Malleable energy wand for maze procedure 失效
标题翻译：用于迷宫程序的可塑性能量棒
公开(公告)号：US20050143721A1
公开(公告)日：2005-06-30
申请号：US11066941
申请日：2005-02-25
申请人： Gregory Brucker , Robert Svenson
发明人： Gregory Brucker , Robert Svenson
IPC分类号： A61B17/00 , A61B17/30 , A61B18/00 , A61B18/18 , A61B18/20 , A61B18/22 , A61B18/24
CPC分类号： A61B18/22 , A61B18/20 , A61B18/24 , A61B2017/00026 , A61B2017/00243 , A61B2017/00247 , A61B2017/306 , A61B2018/00196 , A61B2018/00392 , A61B2018/00636
摘要： A method and apparatus for treating in situ biologic tissue include identifying a patient with a condition susceptible to treatment by forming a lesion in the tissue and accessing a surface of the tissue. A lesion formation tool is positioned against the accessed surface. The tool includes an optical fiber for guiding a coherent waveform of a selected wavelength to a fiber tip for discharge of light energy from the fiber tip. The wavelength is selected for the light energy to penetrate a full thickness of the tissue to form a volume of necrosed tissue through the thickness of the tissue. The tool further includes a guide tip coupled to the fiber tip. The guide tip is adapted to have a discharge bore aligned with the fiber tip to define an unobstructed light pathway from the fiber tip to the tissue surface. The guide tip is further adapted to be placed against the tissue surface with the guide tip slidable along the tissue surface in atraumatic sliding engagement with the discharge bore opposing the tissue surface. The lesion formation tool is manipulated to draw the guide tip over the tissue surface in a pathway while maintaining the discharge bore opposing the tissue surface to form a transmural lesion in the tissue extending a length of the pathway.
摘要翻译：用于治疗原位生物组织的方法和装置包括通过在组织中形成病变并进入组织的表面来识别具有易于治疗的病症的患者。病变形成工具抵靠所访问的表面定位。该工具包括用于将所选波长的相干波形引导到光纤尖端的光纤，用于从光纤尖端排出光能。选择波长以使光能穿透组织的整个厚度，以通过组织的厚度形成一定数量的坏死组织。该工具还包括连接到纤维尖端的引导尖端。引导尖端适于具有与纤维末端对准的排出孔，以限定从纤维尖端到组织表面的无阻碍的光路径。引导尖端进一步适于放置在组织表面上，其中引导尖端沿组织表面滑动，与组织表面相对的排出孔以无创的方式滑动接合。操纵损伤形成工具以将引导尖端在通道中的组织表面上拉伸，同时保持排出孔与组织表面相对，以在组织中形成延伸通路长度的跨壁损伤。

13. 发明申请

US20050090846A1 Valvuloplasty devices and methods 有权
标题翻译：瓣膜成形术装置及方法
公开(公告)号：US20050090846A1
公开(公告)日：2005-04-28
申请号：US10856494
申请日：2004-05-27
申请人： Wesley Pedersen , Robert Van Tassel , Robert Schwartz , Gregory Brucker , Skott Greenhalgh
发明人： Wesley Pedersen , Robert Van Tassel , Robert Schwartz , Gregory Brucker , Skott Greenhalgh
IPC分类号： A61B17/00 , A61B17/22 , A61D1/02 , A61M20060101 , A61M25/10 , A61M29/00 , A61M29/02 , A61M31/00 , A61M37/00
CPC分类号： A61B17/22 , A61B17/3207 , A61B17/320725 , A61B2017/00783 , A61B2017/22051 , A61B2017/22061 , A61B2017/22098 , A61F2/013 , A61F2/2433 , A61M25/10 , A61M25/1002 , A61M25/104 , A61M29/02 , A61M2025/1059
摘要： The present invention provides an aortic valvuloplasty catheter which, in one preferred embodiment, has a tapered distal balloon segment that anchors within the left ventricle outflow track of the patient's heart and a rounded proximal segment which conforms to the aortic sinuses forcing the valve leaflets open. In addition, this embodiment of the valvuloplasty catheter includes a fiber-based balloon membrane, a distal pigtail end hole catheter tip, and a catheter sheath.
摘要翻译：本发明提供了一种主动脉瓣膜成形术导管，其在一个优选实施例中具有楔形的远侧气囊段，其锚定在患者心脏的左心室流出轨道内，并且圆形近端段符合主动脉窦，迫使瓣膜小叶开放。此外，瓣膜成形术导管的该实施例包括纤维基球囊膜，远端猪尾端孔导管末端和导管鞘。

14. 发明申请

US20070073281A1 Guided ablation with motion control 审中-公开
标题翻译：引导消融与运动控制
公开(公告)号：US20070073281A1
公开(公告)日：2007-03-29
申请号：US11385358
申请日：2006-03-20
申请人： Kevin Johnson , Dana Mester , Gregory Brucker , Paul Asselin , Robert Clapp , Adam Berman
发明人： Kevin Johnson , Dana Mester , Gregory Brucker , Paul Asselin , Robert Clapp , Adam Berman
IPC分类号： A61B18/18
CPC分类号： A61B18/24 , A61B18/02 , A61B18/1492 , A61B90/11 , A61B2017/00243 , A61B2018/00196 , A61B2018/2288
摘要： An apparatus for forming a lesion in tissue along a desired ablation path includes a guide member having a tissue-opposing surface for placement against a heart surface. A guide carriage is sized to be received within the guide member and moveable therein along a longitudinal axis. A flexible tubular member extends from a proximal end of said carriage and through a length of the guide member with the tubular member adapted to move the carriage within the guide member upon application of a force to the tubular member. A system urges the carriage to move in a path along an axis of the guide member by amount substantially identical to a displacement of a force application location on the flexible tubular member.
摘要翻译：用于沿着期望的消融路径在组织中形成病变的装置包括具有用于放置在心脏表面上的组织相对表面的引导构件。引导托架的尺寸被设计成被容纳在引导构件内并沿着纵向轴线在其中可移动。柔性管状构件从所述托架的近端延伸并且穿过引导构件的长度，其中管状构件适于在对管状构件施加力时将托架移动到引导构件内。系统促使滑架沿着引导构件的轴线的路径移动，其量基本上与柔性管状构件上的施力位置的位移相同。

15. 发明申请

US20070073277A1 Controlled guided ablation treatment 审中-公开
标题翻译：受控引导消融治疗
公开(公告)号：US20070073277A1
公开(公告)日：2007-03-29
申请号：US11385317
申请日：2006-03-20
申请人： Kevin Johnson , Dana Mester , Gregory Brucker , Paul Asselin , Robert Clapp , Adam Berman
发明人： Kevin Johnson , Dana Mester , Gregory Brucker , Paul Asselin , Robert Clapp , Adam Berman
IPC分类号： A61B18/18
CPC分类号： A61B18/22 , A61B5/053 , A61B5/0538 , A61B5/117 , A61B18/20 , A61B18/24 , A61B2017/00026 , A61B2017/00084 , A61B2017/00115 , A61B2017/00243 , A61B2017/00247 , A61B2017/0243 , A61B2017/306 , A61B2017/3488 , A61B2018/00011 , A61B2018/00196 , A61B2018/00392 , A61B2018/00577 , A61B2018/00636 , A61B2018/2288 , A61B2090/064
摘要： An apparatus for forming a lesion in tissue along a desired ablation path includes a guide member having a tissue-opposing surface for placement against a heart surface. A guide carriage is sized to be received within the guide member and moveable along a longitudinal axis of the guide member. A tubular member extends from a proximal end of the carriage and out a proximal end of the guide member. An ablation element is carried in the carriage for movement. The ablation member is connected to a source of ablation energy through the tubular member. A sensor is provided for sensing a safety condition. The sensor is connected to a monitor external the guide member.
摘要翻译：用于沿着期望的消融路径在组织中形成病变的装置包括具有用于放置在心脏表面上的组织相对表面的引导构件。导向架的尺寸被设计成被容纳在引导构件内并且可以沿着引导构件的纵向轴线移动。管状构件从托架的近端延伸并且从引导构件的近端延伸出来。在滑架中携带消融元件用于移动。消融构件通过管状构件连接到消融能量源。提供传感器用于感测安全条件。传感器连接到引导构件外部的监视器。

16. 发明申请

US20060285793A1 Side-firing laser 失效
公开(公告)号：US20060285793A1
公开(公告)日：2006-12-21
申请号：US11155348
申请日：2005-06-17
申请人： John Brekke , Gregory Brucker
发明人： John Brekke , Gregory Brucker
IPC分类号： G02B6/42 , G02B6/26 , G02B6/02
CPC分类号： A61B18/24 , A61B2018/2272 , G02B6/241 , G02B6/262
摘要： An apparatus for transmitting laser light and redirecting the light laterally relative to an axis of the apparatus includes an optical fiber having both a core and a cladding surrounding the core. The optical fiber terminates at a distal tip having a surface inclined relative to the axis of the optical fiber. A tubular member surrounds the optical fiber at its distal end. The distal end of the optical fiber has a portion opposing the tubular member for being united to the tubular member. The distal portion is joined to the tubular member by an intermediate material selected to have an index of refraction matching that of the core and the tubular member.

17. 发明申请

US20050209589A1 Assessment of lesion transmurality 失效
标题翻译：病变透壁性评估
公开(公告)号：US20050209589A1
公开(公告)日：2005-09-22
申请号：US11133900
申请日：2005-05-19
申请人： Adam Berman , Gregory Brucker , Robert Svenson
发明人： Adam Berman , Gregory Brucker , Robert Svenson
IPC分类号： A61B17/00 , A61B17/30 , A61B18/00 , A61B18/18 , A61B18/20 , A61B18/22 , A61B18/24
CPC分类号： A61B18/22 , A61B18/20 , A61B18/24 , A61B2017/00026 , A61B2017/00243 , A61B2017/00247 , A61B2017/306 , A61B2018/00029 , A61B2018/00196 , A61B2018/00392 , A61B2018/00636
摘要： A method and apparatus for treating a body tissue in situ (e.g., an atrial tissue of a heart to treat) atrial fibrillation include a lesion formation tool is positioned against the heart surface. The lesion formation tool includes a guide member having a tissue-opposing surface for placement against a heart surface. An ablation member is coupled to the guide member to move in a longitudinal path relative to the guide member. The ablation member has an ablation element for directing ablation energy in an emitting direction away from the tissue-opposing surface. The guide member may be flexible to adjust a shape of the guide member for the longitudinal path to approximate the desired ablation path while maintaining the tissue-opposing surface against the heart surface. In one embodiment, the ablation member includes at least one radiation-emitting member disposed to travel in the longitudinal pathway. Transmurality can be assessed to approximate a location of non-transmurality in a formed lesion.
摘要翻译：一种用于原位处理身体组织（例如，心脏的心房组织以治疗）心房颤动的方法和装置包括将病变形成工具定位在心脏表面上。损伤形成工具包括具有用于放置在心脏表面上的组织相对表面的引导构件。消融构件联接到引导构件以相对于引导构件在纵向路径中移动。消融构件具有消融元件，用于将发射方向上的消融能量远离组织相对表面。引导构件可以是柔性的，以调节用于纵向路径的引导构件的形状以接近所需的消融路径，同时将组织相对表面保持抵靠心脏表面。在一个实施例中，消融构件包括设置成在纵向通路中行进的至少一个辐射发射构件。透视性可以被评估以在形成的病变中近似非透壁的位置。

18. 发明申请

US20050159734A1 Atraumatic laser tip for atrial fibrillation treatment 失效
标题翻译：无创激光尖端用于房颤治疗
公开(公告)号：US20050159734A1
公开(公告)日：2005-07-21
申请号：US11080855
申请日：2005-03-15
申请人： Gregory Brucker , Robert Svenson
发明人： Gregory Brucker , Robert Svenson
IPC分类号： A61B17/00 , A61B17/30 , A61B18/00 , A61B18/18 , A61B18/20 , A61B18/22 , A61B18/24
CPC分类号： A61B18/22 , A61B18/20 , A61B18/24 , A61B2017/00026 , A61B2017/00243 , A61B2017/00247 , A61B2017/306 , A61B2018/00196 , A61B2018/00392 , A61B2018/00636
摘要： A method and apparatus for treating in situ biologic tissue include identifying a patient with a condition susceptible to treatment by forming a lesion in the tissue and accessing a surface of the tissue. A lesion formation tool is positioned against the accessed surface. The tool includes an optical fiber for guiding a coherent waveform of a selected wavelength to a fiber tip for discharge of light energy from the fiber tip. The wavelength is selected for the light energy to penetrate a full thickness of the tissue to form a volume of necrosed tissue through the thickness of the tissue. The tool further includes a guide tip coupled to the fiber tip. The guide tip is adapted to have a discharge bore aligned with the fiber tip to define an unobstructed light pathway from the fiber tip to the tissue surface. The guide tip is further adapted to be placed against the tissue surface with the guide tip slidable along the tissue surface in atraumatic sliding engagement with the discharge bore opposing the issue surface. The lesion formation tool is manipulated to draw the guide tip over the tissue surface in a pathway while maintaining the discharge bore opposing the tissue surface to form a transmural lesion in the tissue extending a length of the pathway.
摘要翻译：用于治疗原位生物组织的方法和装置包括通过在组织中形成病变并进入组织的表面来识别具有易于治疗的病症的患者。病变形成工具抵靠所访问的表面定位。该工具包括用于将所选波长的相干波形引导到光纤尖端的光纤，用于从光纤尖端排出光能。选择波长以使光能穿透组织的整个厚度，以通过组织的厚度形成一定数量的坏死组织。该工具还包括连接到纤维尖端的引导尖端。引导尖端适于具有与纤维末端对准的排出孔，以限定从纤维尖端到组织表面的无阻碍的光路径。引导尖端进一步适于被放置在组织表面上，其中引导尖端可沿组织表面滑动，与与检查表面相对的排出孔无创伤滑动接合。操纵损伤形成工具以将引导尖端在通道中的组织表面上拉伸，同时保持排出孔与组织表面相对，以在组织中形成延伸通路长度的跨壁损伤。

19. 发明申请

US20050143722A1 Laser-based maze procedure for atrial fibrillation 失效
标题翻译：用于心房颤动的基于激光的迷宫程序
公开(公告)号：US20050143722A1
公开(公告)日：2005-06-30
申请号：US11067131
申请日：2005-02-25
申请人： Gregory Brucker , Robert Svenson
发明人： Gregory Brucker , Robert Svenson
IPC分类号： A61B17/00 , A61B17/30 , A61B18/00 , A61B18/18 , A61B18/20 , A61B18/22 , A61B18/24
CPC分类号： A61B18/22 , A61B18/20 , A61B18/24 , A61B2017/00026 , A61B2017/00243 , A61B2017/00247 , A61B2017/306 , A61B2018/00196 , A61B2018/00392 , A61B2018/00636
摘要： A method and apparatus for treating in situ biologic tissue include identifying a patient with a condition susceptible to treatment by forming a lesion in the tissue and accessing a surface of the tissue. A lesion formation tool is positioned against the accessed surface. The tool includes an optical fiber for guiding a coherent waveform of a selected wavelength to a fiber tip for discharge of light energy from the fiber tip. The wavelength is selected for the light energy to penetrate a full thickness of the tissue to form a volume of necrosed tissue through the thickness of the tissue. The tool further includes a guide tip coupled to the fiber tip. The guide tip is adapted to have a discharge bore aligned with the fiber tip to define an unobstructed light pathway from the fiber tip to the tissue surface. The guide tip is further adapted to be placed against the tissue surface with the guide tip slidable along the tissue surface in atraumatic sliding engagement with the discharge bore opposing the tissue surface. The lesion formation tool is manipulated to draw the guide tip over the tissue surface in a pathway while maintaining the discharge bore opposing the tissue surface to form a transmural lesion in the tissue extending a length of the pathway.
摘要翻译：用于治疗原位生物组织的方法和装置包括通过在组织中形成病变并进入组织的表面来识别具有易于治疗的病症的患者。病变形成工具抵靠所访问的表面定位。该工具包括用于将所选波长的相干波形引导到光纤尖端的光纤，用于从光纤尖端排出光能。选择波长以使光能穿透组织的整个厚度，以通过组织的厚度形成一定数量的坏死组织。该工具还包括连接到纤维尖端的引导尖端。引导尖端适于具有与纤维末端对准的排出孔，以限定从纤维尖端到组织表面的无阻碍的光路径。引导尖端进一步适于放置在组织表面上，其中引导尖端沿组织表面滑动，与组织表面相对的排出孔以无创的方式滑动接合。操纵损伤形成工具以将引导尖端在通道中的组织表面上拉伸，同时保持排出孔与组织表面相对，以在组织中形成延伸通路长度的跨壁损伤。

20. 发明授权

US06425894B1 Ablation catheter with electrode temperature monitoring 有权
标题翻译：消融导管与电极温度监测
公开(公告)号：US06425894B1
公开(公告)日：2002-07-30
申请号：US09614362
申请日：2000-07-12
申请人： Gregory Brucker , William Penny
发明人： Gregory Brucker , William Penny
IPC分类号： A61B1818
CPC分类号： A61B18/1492 , A61B18/14 , A61B2018/00214 , A61B2018/00654 , A61B2018/00797 , A61B2018/00821 , A61B2018/00898 , A61B2018/124
摘要： An ablation catheter is provided which comprises an elongated catheter body, a plurality of electrodes, and a thermal monitoring circuit. The thermal monitoring circuit is comprised of a plurality of thermocouples joined in series. The thermocouples thermoconductively coupled to the electrodes. The thermal monitoring circuit will require only two wires to travel through the elongated catheter body in order to monitor a plurality of electrodes.
摘要翻译：提供消融导管，其包括细长的导管主体，多个电极和热监测电路。热监测电路由串联连接的多个热电偶组成。热电偶热电耦合到电极。热监测电路将仅需要两条电线穿过细长的导管体，以便监测多个电极。

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