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11. 发明授权

US08428398B2 Hand-held portable microarray reader for biodetection 有权
标题翻译：手持便携式微阵列读取器，用于生物检测
公开(公告)号：US08428398B2
公开(公告)日：2013-04-23
申请号：US12826215
申请日：2010-06-29
申请人： Deanna Lynn Thompson , Matthew A. Coleman , Stephen M. Lane , Dennis L. Matthews , Joanna Albala , Sebastian Wachsmann-Hogiu
发明人： Deanna Lynn Thompson , Matthew A. Coleman , Stephen M. Lane , Dennis L. Matthews , Joanna Albala , Sebastian Wachsmann-Hogiu
IPC分类号： G06K9/22
CPC分类号： G06K9/22 , H04N5/335
摘要： A hand-held portable microarray reader for biodetection includes a microarray reader engineered to be small enough for portable applications. The invention includes a high-powered light-emitting diode that emits excitation light, an excitation filter positioned to receive the excitation light, a slide, a slide holder assembly for positioning the slide to receive the excitation light from the excitation filter, an emission filter positioned to receive the excitation light from the slide, a lens positioned to receive the excitation light from the emission filter, and a CCD camera positioned to receive the excitation light from the lens.
摘要翻译：用于生物检测的手持便携式微阵列读取器包括被设计为足够小以用于便携式应用的微阵列读取器。本发明包括发射激发光的大功率发光二极管，定位成接收激发光的激发滤光器，滑块，用于定位滑块以接收来自激发滤光器的激发光的滑块保持器组件，发射滤光片定位成接收来自滑块的激发光，定位成接收来自发射滤光器的激发光的透镜，以及定位成接收来自透镜的激发光的CCD照相机。

12. 发明申请

US20110188782A1 Hand-Held Portable Microarray Reader For Biodetection 有权
标题翻译：手持式便携式微阵列读取器，用于生物检测
公开(公告)号：US20110188782A1
公开(公告)日：2011-08-04
申请号：US12826215
申请日：2010-06-29
申请人： Deanna Lynn Thompson , Matthew A. Coleman , Stephen M. Lane , Dennis L. Matthews , Joanna Albala , Sebastian Wachsmann-Hogiu
发明人： Deanna Lynn Thompson , Matthew A. Coleman , Stephen M. Lane , Dennis L. Matthews , Joanna Albala , Sebastian Wachsmann-Hogiu
IPC分类号： G06K9/22 , H04N5/335
CPC分类号： G06K9/22 , H04N5/335
摘要： A hand-held portable microarray reader for biodetection includes a microarray reader engineered to be small enough for portable applications. The invention includes a high-powered light-emitting diode that emits excitation light, an excitation filter positioned to receive the excitation light, a slide, a slide holder assembly for positioning the slide to receive the excitation light from the excitation filter, an emission filter positioned to receive the excitation light from the slide, a lens positioned to receive the excitation light from the emission filter, and a CCD camera positioned to receive the excitation light from the lens.
摘要翻译：用于生物检测的手持便携式微阵列读取器包括被设计为足够小以用于便携式应用的微阵列读取器。本发明包括发射激发光的大功率发光二极管，定位成接收激发光的激发滤光器，滑块，用于定位滑块以接收来自激发滤光器的激发光的滑块保持器组件，发射滤光片定位成接收来自滑块的激发光，定位成接收来自发射滤光器的激发光的透镜，以及定位成接收来自透镜的激发光的CCD照相机。

13. 发明申请

US20080200342A1 Device, Array, And Methods For Disease Detection And Analysis 审中-公开
标题翻译：设备，阵列和疾病检测和分析方法
公开(公告)号：US20080200342A1
公开(公告)日：2008-08-21
申请号：US12031625
申请日：2008-02-14
申请人： Rupa S. Rao , Stephen M. Lane , Dennis L. Matthews , Matthew A. Coleman
发明人： Rupa S. Rao , Stephen M. Lane , Dennis L. Matthews , Matthew A. Coleman
IPC分类号： C40B30/04 , C40B60/12 , C40B30/00
CPC分类号： G01N33/543 , B01J19/0046 , B01J2219/00385 , B01J2219/00549 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00725 , B01L3/5025 , B01L3/5027 , B01L3/50273 , C40B60/12
摘要： A device and array coupled to capture molecules are provided. Specifically, the device and array can be used for detecting the presence and concentration of biomarkers in a sample from a subject. The device and array can also allow the use of a method for scoring a sample for, e.g., the purpose of diagnosing a disease. The method can also be advantageous to applications where there is a need to accurately determine the disease stage of a subject for the purpose of making therapeutic decisions.
摘要翻译：提供耦合到捕获分子的装置和阵列。具体地，该装置和阵列可用于检测来自受试者的样品中生物标志物的存在和浓度。装置和阵列还可以使用用于评估样品的方法，例如用于诊断疾病的目的。该方法对于需要准确地确定受试者的疾病阶段以进行治疗决定的应用也是有利的。

14. 发明授权

US06740094B2 Shape memory polymer actuator and catheter 有权
公开(公告)号：US06740094B2
公开(公告)日：2004-05-25
申请号：US09761023
申请日：2001-01-16
申请人： Duncan J. Maitland , Abraham P. Lee , Daniel L. Schumann , Dennis L. Matthews , Derek E. Decker , Charles A. Jungreis
发明人： Duncan J. Maitland , Abraham P. Lee , Daniel L. Schumann , Dennis L. Matthews , Derek E. Decker , Charles A. Jungreis
IPC分类号： A61F1100
CPC分类号： A61B17/32075 , A61B17/22031 , A61B17/221 , A61B17/320725 , A61B2017/00398 , A61B2017/00867 , A61B2017/00871 , A61B2017/22034 , A61B2017/320064 , A61M25/0158 , A61M2025/0064
摘要： An actuator system is provided for acting upon a material in a vessel. The system includes an optical fiber and a shape memory polymer material operatively connected to the optical fiber. The shape memory polymer material is adapted to move from a first shape for moving through said vessel to a second shape where it can act upon said material.

15. 发明授权

US5016250A X-ray lasers and methods utilizing two component driving illumination provided by optical laser means of relatively low energy and small physical size 失效
标题翻译： X射线激光器和利用由相对较低能量和小物理尺寸的光学激光装置提供的双分量驱动照明的方法
公开(公告)号：US5016250A
公开(公告)日：1991-05-14
申请号：US423165
申请日：1989-10-18
申请人： Mordecai D. Rosen , Dennis L. Matthews
发明人： Mordecai D. Rosen , Dennis L. Matthews
IPC分类号： H01S4/00
CPC分类号： H01S4/00
摘要： An X-ray laser (10), and related methodology, are disclosed wherein an X-ray laser target (12) is illuminated with a first pulse of optical laser radiation (14) of relatively long duration having scarcely enough energy to produce a narrow and linear cool plasma of uniform composition (38). A second, relatively short pulse of optical laser radiation (18) is uniformly swept across the length, from end to end, of the plasma (38), at about the speed of light, to consecutively illuminate continuously succeeding portions of the plasma (38) with optical laser radiation having scarcely enough energy to heat, ionize, and invert them into the continuously succeeding portions of an X-ray gain medium. This inventive double pulse technique results in a saving of more than two orders of magnitude in driving optical laser energy, when compared to the conventional single pulse approach.
摘要翻译：公开了一种X射线激光器（10）和相关方法，其中用相对长的持续时间的第一脉冲光学激光辐射（14）照射X射线激光靶（12），其具有几乎不足够的能量以产生狭窄的和均匀组成的线性冷等离子体（38）。光束激光辐射的第二个相对较短的脉冲（18）以大约光速从头端到末端均匀地扫过等离子体（38）的长度，以连续地照亮等离子体（38）的连续后续部分），其具有几乎不足够的能量以加热，电离和将它们转换成X射线增益介质的连续后续部分的光学激光辐射。与传统的单脉冲方法相比，本发明的双脉冲技术在驱动光学激光能量方面节省了两个以上的数量级。

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