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11. 发明授权

US07319905B1 Passive fixation mechanism for epicardial sensing and stimulation lead placed through pericardial access 有权
公开(公告)号：US07319905B1
公开(公告)日：2008-01-15
申请号：US11121881
申请日：2005-05-03
申请人： Kevin L. Morgan , Michael Yang , Sheldon Williams , Andrew W. McGarvey
发明人： Kevin L. Morgan , Michael Yang , Sheldon Williams , Andrew W. McGarvey
IPC分类号： A61N1/05
CPC分类号： A61N1/0587
摘要： An implantable lead having an elongated lead body that includes an electrical conductor extending between a distal end of the lead body and a proximal end of the lead body is disclosed. The lead further includes an electrode formed at the distal end of the lead body, the electrode being coupled to the electrical conductor and one or more passive fixation mesh sections coupled to the distal end of the lead body that promotes tissue over growth.

12. 发明授权

US08538555B1 Cardiac access methods and apparatus 有权
标题翻译：心脏存取方法和装置
公开(公告)号：US08538555B1
公开(公告)日：2013-09-17
申请号：US12973810
申请日：2010-12-20
申请人： Yougandh Chitre , Gene A. Bornzin , John R. Helland , Eric Falkenberg , Kevin L. Morgan , Sheldon Williams , Michael Yang , Andrew W. McGarvey
发明人： Yougandh Chitre , Gene A. Bornzin , John R. Helland , Eric Falkenberg , Kevin L. Morgan , Sheldon Williams , Michael Yang , Andrew W. McGarvey
IPC分类号： A61N1/00
CPC分类号： A61F2/2478 , A61B17/00 , A61B17/0057 , A61N1/0587
摘要： A chamber or vasculature of a heart may be accessed via the pericardial space of the heart. Initially, the pericardial space may be accessed via a transmyocardial approach or a subxiphoid approach. A lead or other implantable apparatus may thus be routed into the pericardial space, through myocardial tissue and into the chamber or vasculature. The lead or other apparatus may be used to sense activity in or provide therapy to the heart.
摘要翻译：可以通过心脏的心包空间访问心脏的腔室或脉管系统。最初，心包空间可以通过心肌的方法或亚型的方法进行。因此，引线或其它可植入装置可通过心肌组织进入心包空间并进入腔室或脉管系统。铅或其他装置可用于感测心脏的活动或提供对心脏的治疗。

13. 发明授权

US08311648B1 Cardiac access methods and apparatus 有权
标题翻译：心脏存取方法和装置
公开(公告)号：US08311648B1
公开(公告)日：2012-11-13
申请号：US12973800
申请日：2010-12-20
申请人： Yougandh Chitre , Gene A. Bornzin , John R. Helland , Eric Falkenberg , Kevin L. Morgan , Sheldon Williams , Michael Yang , Andrew W. McGarvey
发明人： Yougandh Chitre , Gene A. Bornzin , John R. Helland , Eric Falkenberg , Kevin L. Morgan , Sheldon Williams , Michael Yang , Andrew W. McGarvey
IPC分类号： A61N1/05
CPC分类号： A61F2/2478 , A61B17/00 , A61B17/0057 , A61N1/0587
摘要： A delivery apparatus for accessing the pericardial space of a heart including an elongated body defining a lumen and a piercing member that extends from a distal portion of the elongated body for piercing tissue of the heart. A spring expands from a distal end of the piercing member in response to the distal end of the piercing member passing through the tissue and into the pericardial space. An electrode located on the spring in order to sense signals indicative of a distal end of the spring passing through the tissue and into the pericardial space.
摘要翻译：一种用于进入心脏的心包空间的输送装置，包括限定内腔的细长主体和从细长主体的远端部分延伸以刺穿心脏的组织的穿刺构件。响应于刺穿构件的远端穿过组织并进入心包空间，弹簧从穿刺构件的远端膨胀。位于弹簧上的电极，用于感测指示穿过组织并进入心包空间的弹簧的远端的信号。

14. 发明申请

US20110106233A1 INTRAPERICARDIAL LEAD 有权
标题翻译：国内领先
公开(公告)号：US20110106233A1
公开(公告)日：2011-05-05
申请号：US13005448
申请日：2011-01-12
申请人： Kevin L. Morgan , Steven R. Conger , Anna Barlow , Stuart Rosenberg , Wenbo Hou , Michael Yang , Sheldon Williams
发明人： Kevin L. Morgan , Steven R. Conger , Anna Barlow , Stuart Rosenberg , Wenbo Hou , Michael Yang , Sheldon Williams
IPC分类号： A61N1/05
CPC分类号： A61N1/059 , A61N1/057 , A61N1/0587 , A61N2001/058
摘要： The intrapericardial lead includes a lead body having a proximal portion and a flexible, pre-curved distal end portion. The distal end portion carries at least one electrode assembly containing an electrode adapted to engage pericardial tissue. The distal end portion further carries a pre-curved flexible wire member having ends attached to spaced apart points along the distal end portion of the lead body, the flexible wire member having a normally expanded state wherein an intermediate portion of the wire member is spaced apart from the distal end portion, and a generally straightened state wherein the wire member and the distal end portion are disposed in a more parallel, adjacent relationship so as to present a small frontal area to facilitate delivery into the pericardial space. The wire member re-expands to its normal state after delivery into the pericardial space to anchor the distal end portion of the lead body relative to the pericardial tissue.
摘要翻译：心包内引线包括具有近端部分和柔性的预弯曲远端部分的引线体。远端部分携带至少一个电极组件，其包含适于接合心包组织的电极。远端部分还承载预弯曲的柔性线构件，其具有沿着引线本体的远端部附接到间隔开的点的端部，柔性线构件具有正常膨胀状态，其中线构件的中间部分间隔开以及大致直线状态，其中所述线构件和所述远端部分布置成更平行的相邻关系，以便呈现小的前部区域以便于输送到心包空间中。导线部件在输送到心包空间之后再膨胀至正常状态，以相对于心包组织锚固引线主体的远端部分。

15. 发明授权

US09002478B1 Passive fixation for epicardial lead 有权
标题翻译：被动固定为心外膜导联
公开(公告)号：US09002478B1
公开(公告)日：2015-04-07
申请号：US13036821
申请日：2011-02-28
申请人： Michael Yang , Wenbo Hou , Sheldon Williams
发明人： Michael Yang , Wenbo Hou , Sheldon Williams
IPC分类号： A61N1/00 , A61N1/05
CPC分类号： A61N1/0587
摘要： An epicardial lead is passively fixed in a pericardial space by a passive fixation member. The passive fixation member extends from a distal portion of an epicardial lead and acts against a pericardial layer and an epicardial layer to hold the lead in place. The epicardial lead may include an electrode that is connected to a conductor that extends from a distal portion of the lead. In some embodiments the epicardial lead includes a material that promotes fibrosis to fix the lead to heart tissue. The passive fixation member may include a shocking coil.
摘要翻译：心外膜由被动固定构件被动地固定在心包空间中。被动固定构件从心外膜引导件的远端部分延伸并作用于心包层和心外膜层以将引线保持在适当位置。心外膜引线可以包括连接到从引线的远端部分延伸的导体的电极。在一些实施方案中，心外膜引线包括促进纤维化以将引线固定到心脏组织的材料。被动固定构件可包括震动线圈。

16. 发明授权

US07922648B1 Myocardial infarction patch for minimally invasive implant 有权
标题翻译：用于微创植入物的心肌梗死贴片
公开(公告)号：US07922648B1
公开(公告)日：2011-04-12
申请号：US11354698
申请日：2006-02-14
申请人： Wenbo Hou , Sheldon Williams
发明人： Wenbo Hou , Sheldon Williams
IPC分类号： A61F2/00 , A61F2/02
CPC分类号： A61F2/2481
摘要： A fixation section and a rim form a myocardial patch for implant in the pericardial space. The fixation section is adapted to promote fibrosis to secure the patch in place. The rim is secured to and surrounds at least a portion of the fixation section and has a lumen. The patch is adapted to transition between a collapsed state and an expanded state. A stylet is passed through the lumen to force the patch into a collapsed state and is removed when the patch is positioned to allow the patch to expand and engage the epicardial surface.
摘要翻译：固定部分和边缘形成用于在心包空间中植入的心肌贴片。固定部分适于促进纤维化以将贴片固定到位。轮缘被固定到并围绕固定部分的至少一部分并且具有内腔。贴片适于在折叠状态和展开状态之间转换。探针通过管腔以迫使贴片处于折叠状态，并且当贴片被定位以允许贴片膨胀并接合心外膜表面时被移除。

17. 发明授权

US07920928B1 Passive fixation for epicardial lead 有权
标题翻译：被动固定为心外膜导联
公开(公告)号：US07920928B1
公开(公告)日：2011-04-05
申请号：US11669797
申请日：2007-01-31
申请人： Michael Yang , Wenbo Hou , Sheldon Williams
发明人： Michael Yang , Wenbo Hou , Sheldon Williams
IPC分类号： A61N1/00
CPC分类号： A61N1/0587
摘要： An epicardial lead is passively fixed in a pericardial space by a passive fixation member. The passive fixation member extends from a distal portion of an epicardial lead and acts against a pericardial layer and an epicardial layer to hold the lead in place. The epicardial lead may include an electrode that is connected to a conductor that extends from a distal portion of the lead. In some embodiments the epicardial lead includes a material that promotes fibrosis to fix the lead to heart tissue. The passive fixation member may include a shocking coil.
摘要翻译：心外膜由被动固定构件被动地固定在心包空间中。被动固定构件从心外膜引导件的远端部分延伸并作用于心包层和心外膜层以将引线保持在适当位置。心外膜引线可以包括连接到从引线的远端部分延伸的导体的电极。在一些实施方案中，心外膜引线包括促进纤维化以将引线固定到心脏组织的材料。被动固定构件可包括震动线圈。

18. 发明授权

US07433739B1 Passive fixation mechanism for epicardial sensing and stimulation lead placed through pericardial access 有权
标题翻译：被动心脏传导和刺激的被动固定机制通过心包通路进行放置
公开(公告)号：US07433739B1
公开(公告)日：2008-10-07
申请号：US11001374
申请日：2004-11-30
申请人： Scott Salys , Chris Parrillo , Matt Phillips , Luz Padilla , Jnyan Patel , Kevin L. Morgan , Michael Yang , Sheldon Williams , Andrew W. McGarvey
发明人： Scott Salys , Chris Parrillo , Matt Phillips , Luz Padilla , Jnyan Patel , Kevin L. Morgan , Michael Yang , Sheldon Williams , Andrew W. McGarvey
IPC分类号： A61N1/05
CPC分类号： A61N1/0587
摘要： An implantable lead having an elongated lead body that includes an electrical conductor extending between a distal end of the lead body and a proximal end of the lead body is disclosed. The lead further includes an electrode formed at the distal end of the lead body, the electrode being coupled to the electrical conductor and one or more passive fixation mesh sections coupled to the distal end of the lead body that promotes tissue over growth.
摘要翻译：公开了一种具有细长引线主体的可植入引线，其包括在引线主体的远端和引线主体的近端之间延伸的电导体。引线还包括形成在引线主体的远端处的电极，电极耦合到电导体和耦合到引线主体的远端的一个或多个被动固定网孔部分，其促进组织过度生长。

19. 发明授权

US07369901B1 Myocardial lead and lead system 有权
标题翻译：心肌铅和铅系统
公开(公告)号：US07369901B1
公开(公告)日：2008-05-06
申请号：US11056666
申请日：2005-02-10
申请人： Kevin L. Morgan , John R. Helland , Sheldon Williams , Yougandh Chitre , Andrew W. McGarvey , Christopher Fleck , Jnyan Patel , Scott Salys , Kerwyn Schimke
发明人： Kevin L. Morgan , John R. Helland , Sheldon Williams , Yougandh Chitre , Andrew W. McGarvey , Christopher Fleck , Jnyan Patel , Scott Salys , Kerwyn Schimke
IPC分类号： A61N1/362 , A61N1/05
CPC分类号： A61N1/059
摘要： An implantable myocardial stimulation lead comprises a lead body having a distal end and a proximal end, and an electrical connector carried by the proximal end of the lead body. An electrode header carried by the distal end of the lead body has an axis and includes a helical fixation element extending along the axis, the electrode header having a surface configured to receive a driver for rotating the electrode header to screw the helical fixation element into the tissue of the heart. The lead body carries along its length a strain relief member resisting excessive bending of the lead body.
摘要翻译：植入式心肌刺激引线包括具有远端和近端的引线主体和由引线主体的近端承载的电连接器。由引线主体的远端承载的电极头具有轴线并且包括沿着轴线延伸的螺旋固定元件，电极头具有被配置为接收驱动器的表面，该驱动器用于旋转电极头以将螺旋固定元件拧入心脏的组织引线体沿其长度方向承载抵抗引线体的过度弯曲的应变消除部件。

20. 发明申请

US20070239244A1 INTRAPERICARDIAL LEAD 有权
标题翻译：国内领先
公开(公告)号：US20070239244A1
公开(公告)日：2007-10-11
申请号：US11691335
申请日：2007-03-26
申请人： Kevin L. Morgan , Steven R. Conger , Anna Barlow , Stuart Rosenberg , Wenbo Hou , Michael Yang , Sheldon Williams
发明人： Kevin L. Morgan , Steven R. Conger , Anna Barlow , Stuart Rosenberg , Wenbo Hou , Michael Yang , Sheldon Williams
IPC分类号： A61N1/05
CPC分类号： A61N1/059 , A61N1/057 , A61N1/0587 , A61N2001/058
摘要： The intrapericardial lead includes a lead body having a proximal portion and a flexible, pre-curved distal end portion. The distal end portion carries at least one electrode assembly containing an electrode adapted to engage pericardial tissue. The distal end portion further carries a pre-curved flexible wire member having ends attached to spaced apart points along the distal end portion of the lead body, the flexible wire member having a normally expanded state wherein an intermediate portion of the wire member is spaced apart from the distal end portion, and a generally straightened state wherein the wire member and the distal end portion are disposed in a more parallel, adjacent relationship so as to present a small frontal area to facilitate delivery into the pericardial space. The wire member re-expands to its normal state after delivery into the percaridal space to anchor the distal end portion of the lead body relative to the pericardial tissue.
摘要翻译：心包内引线包括具有近端部分和柔性的预弯曲远端部分的引线体。远端部分携带至少一个电极组件，其包含适于接合心包组织的电极。远端部分还承载预弯曲的柔性线构件，其具有沿着引线本体的远端部附接到间隔开的点的端部，柔性线构件具有正常膨胀状态，其中线构件的中间部分间隔开以及大致直线状态，其中所述线构件和所述远端部分布置成更平行的相邻关系，以便呈现小的前部区域以便于输送到心包空间中。导线部件在输送到大面积空间之后，再膨胀至其正常状态，以相对于心包组织锚固引线主体的远端部分。

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