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    • 11. 发明授权
    • Identification of pacing site
    • 鉴定起搏部位
    • US08620432B2
    • 2013-12-31
    • US13171952
    • 2011-06-29
    • Sven-Erik HedbergNils HolmströmJohn GustafssonAndreas BlomqvistAndreas Karlsson
    • Sven-Erik HedbergNils HolmströmJohn GustafssonAndreas BlomqvistAndreas Karlsson
    • A61N1/00
    • A61N1/3686A61N1/36521
    • An implantable medical device applies an electric signal over two electrodes and measures the resulting electric signal over a candidate pair of neighboring electrodes on a lead for a first heart ventricle or over a candidate electrode of the lead and a case electrode. An impedance signal is determined for each candidate pair or electrode based on the applied signal and the measured resulting signal. A time difference between start of contraction in a second ventricle and the timing of local myocardial contraction as identified from the impedance signal at the site of the candidate pair or electrode is determined for each candidate pair or electrode. An optimal pacing electrode is selected to correspond to one of the electrodes of the candidate pair having the largest time difference or the candidate electrode having largest time difference.
    • 可植入医疗装置在两个电极上施加电信号,并且通过在第一心室的引线上或在引线的候选电极和外壳电极上的相邻电极的候选对测量所得到的电信号。 基于所施加的信号和测得的结果信号,为每个候选对或电极确定阻抗信号。 针对每个候选对或电极确定从候选对或电极的位置处的阻抗信号识别的第二心室的收缩开始与局部心肌收缩的定时之间的时间差。 选择最佳起搏电极以对应于具有最大时间差的候选对的电极之一或具有最大时间差的候选电极。
    • 13. 发明申请
    • IDENTIFICATION OF PACING SITE
    • 鉴定场地
    • US20120004700A1
    • 2012-01-05
    • US13171952
    • 2011-06-29
    • Sven-Erik HedbergNils HolmströmJohn GustafssonAndreas BlomqvistAndreas Karlsson
    • Sven-Erik HedbergNils HolmströmJohn GustafssonAndreas BlomqvistAndreas Karlsson
    • A61N1/368
    • A61N1/3686A61N1/36521
    • An implantable medical device applies an electric signal over two electrodes and measures the resulting electric signal over a candidate pair of neighboring electrodes on a lead for a first heart ventricle or over a candidate electrode of the lead and a case electrode. An impedance signal is determined for each candidate pair or electrode based on the applied signal and the measured resulting signal. A time difference between start of contraction in a second ventricle and the timing of local myocardial contraction as identified from the impedance signal at the site of the candidate pair or electrode is determined for each candidate pair or electrode. An optimal pacing electrode is selected to correspond to one of the electrodes of the candidate pair having the largest time difference or the candidate electrode having largest time difference.
    • 可植入医疗装置在两个电极上施加电信号,并且通过在第一心室的引线上或在引线的候选电极和外壳电极上的相邻电极的候选对测量所得到的电信号。 基于所施加的信号和测得的结果信号,为每个候选对或电极确定阻抗信号。 针对每个候选对或电极确定从候选对或电极的位置处的阻抗信号识别的第二心室的收缩开始与局部心肌收缩的定时之间的时间差。 选择最佳起搏电极以对应于具有最大时间差的候选对的电极之一或具有最大时间差的候选电极。
    • 20. 发明授权
    • Biventricular stimulation device with shortened inter-ventricular delay
    • 双心室刺激装置具有缩短的心室间延迟
    • US07353061B2
    • 2008-04-01
    • US10573281
    • 2003-09-25
    • Sven-Erik HedbergAnders BjörlingPer Lagercrantz
    • Sven-Erik HedbergAnders BjörlingPer Lagercrantz
    • A61N1/00
    • A61N1/371A61N1/368A61N1/3684
    • A biventricular cardiac stimulation device has a pulse generator for delivering stimulation pulses at least to the ventricles of a patient's heart. An evoked response detector has independent first and second ventricular sensing channels for ventricular evoked response detection in the ventricles. The pulse generator is controlled to deliver stimulation pulses to the second ventricle with a VV time delay after delivery of a stimulation pulse to the first-stimulated ventricle, the VV time delay being shorter than an evoked response detection time window that follows delivery of the stimulation pulse to the first-stimulated ventricle. An evoked response detector closes the evoked response detection window, or discards detections therein, in response to the emission of a stimulation pulse to the second-stimulated ventricle during the evoked response detection time window of the first-stimulated ventricle.
    • 双心室心脏刺激装置具有脉冲发生器,用于至少向患者心脏的心室输送刺激脉冲。 诱发反应检测器具有独立的第一和第二心室感应通道,用于心室中的心室诱发反应检测。 脉冲发生器被控制以在将刺激脉冲递送到第一刺激心室之后以VV时间延迟将刺激脉冲递送到第二心室,VV时间延迟短于在刺激递送之后的诱发响应检测时间窗口 脉冲到第一刺激的心室。 响应于在第一刺激的心室的诱发响应检测时间窗口期间向第二刺激的心室发射刺激脉冲,诱发响应检测器关闭诱发响应检测窗口或丢弃其中的检测。