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11. 发明申请

US20100171340A1 VEHICLE BODY FRAME STRUCTURE 有权
标题翻译：车身车身结构
公开(公告)号：US20100171340A1
公开(公告)日：2010-07-08
申请号：US12668596
申请日：2008-07-08
申请人： Shigeto Yasuhara , Yasuhisa Egawa , Ken Yasui
发明人： Shigeto Yasuhara , Yasuhisa Egawa , Ken Yasui
IPC分类号： B62D21/02
CPC分类号： B62D25/2018 , B62D21/11 , B62D25/082
摘要： An automobile vehicle compartment includes an octagonal frame having side sills that extend in the vehicle body fore-and-aft direction, a dashboard lower cross member and middle cross member that extend in the vehicle width direction, and four inclined members, and it is therefore possible to ensure that there is sufficient rigidity both for a collision load from the vehicle body fore-and-aft direction and from the side of the vehicle body, thereby minimizing deformation of the vehicle compartment. Furthermore, since front side frames and a front bumper beam form a U-shaped frame that curves in a U-shape toward the vehicle body fore-and-aft direction in front of the vehicle compartment, it is possible by crushing of the high rigidity U-shaped frame to absorb effectively a collision load from the vehicle body fore-and-aft direction, including an offset collision, thereby preventing more effectively deformation of the vehicle compartment.
摘要翻译：汽车车厢包括具有在车体前后方向上延伸的侧梁的八角形框架，沿车宽方向延伸的仪表板下横梁和中横梁，以及四个倾斜构件，因此可以确保对于来自车体前后方向和车体侧面的碰撞负载都具有足够的刚性，从而最小化车厢的变形。此外，由于前侧框架和前保险杠梁形成在车厢前方朝向车身前后方向呈U字形的U字形框架，因此可以通过破碎高刚性 U形框架有效地吸收来自车身前后方向的碰撞载荷，包括偏移碰撞，从而防止车厢更有效地变形。

12. 发明申请

US20100160290A1 PHARMACEUTICAL COMPOSITION FOR TREATING ALZHEIMER'S DISEASE 有权
标题翻译：用于治疗阿尔茨海默病的药物组合物
公开(公告)号：US20100160290A1
公开(公告)日：2010-06-24
申请号：US12597470
申请日：2008-04-23
申请人： Naotake Kobayashi , Kazuo Ueda , Naohiro Itoh , Shinji Suzuki , Gaku Sakaguchi , Akira Kato , Akira Yukimasa , Akihiro Hori , Yuuji Kooriyama , Hidekazu Haraguchi , Ken Yasui , Yasuhiko Kanda
发明人： Naotake Kobayashi , Kazuo Ueda , Naohiro Itoh , Shinji Suzuki , Gaku Sakaguchi , Akira Kato , Akira Yukimasa , Akihiro Hori , Yuuji Kooriyama , Hidekazu Haraguchi , Ken Yasui , Yasuhiko Kanda
IPC分类号： A61K31/554 , C07D417/02 , A61K31/541 , C07D279/06 , C07D277/18 , A61K31/426 , C07D239/02 , A61K31/506 , C07D281/02 , A61P25/28
CPC分类号： C07D471/04 , A61K9/0019 , A61K9/1623 , A61K9/2018 , A61K31/426 , A61K31/506 , A61K31/535 , A61K31/54 , A61K31/541 , A61K31/554 , C07D239/14 , C07D265/08 , C07D277/18 , C07D279/06 , C07D281/02 , C07D285/36 , C07D295/155 , C07D295/192 , C07D405/04 , C07D417/04 , C07D417/10 , C07D417/12 , A61K2300/00
摘要： A pharmaceutical composition for treating Alzheimer's disease containing a compound represented by the general formula (I); wherein ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; E is lower alkylene, etc.; X is S, O, or NR1; R1 is a hydrogen atom or lower alkyl; R2a, R2b, R3a, R3b, R4a and R4b are each independently a hydrogen atom, halogen, hydroxy, etc.; n and m are each independently an integer of 0 to 3; n+m is an integer of 1 to 3; and R5 is a hydrogen atom, optionally substituted lower alkyl, etc.; its pharmaceutically acceptable salt, or a solvate thereof as an active ingredient.
摘要翻译：一种用于治疗含有由通式（I）表示的化合物的阿尔茨海默病的药物组合物; 其中环A是任选取代的碳环基团或任选取代的杂环基团; E为低级亚烷基等; X是S，O或NR1; R1是氢原子或低级烷基; R2a，R2b，R3a，R3b，R4a和R4b各自独立地为氢原子，卤素，羟基等; n和m各自独立地为0〜3的整数， n + m为1〜3的整数， R5为氢原子，任意取代的低级烷基等; 其药学上可接受的盐或其溶剂合物作为活性成分。

13. 发明授权

US07380830B2 Vehicle front body structure 失效
标题翻译：车前体结构
公开(公告)号：US07380830B2
公开(公告)日：2008-06-03
申请号：US11345788
申请日：2006-02-02
申请人： Jun Mitsui , Shigeto Yasuhara , Ken Yasui
发明人： Jun Mitsui , Shigeto Yasuhara , Ken Yasui
IPC分类号： B62D21/00
CPC分类号： B60T17/046 , B62D21/02 , B62D21/152 , B62D25/16
摘要： A vehicle front body structure includes a hollow front side frame of closed cross-sectional structure having a wheel relief portion having a horizontal width reducing to allow swivel movement of a front wheel of the vehicle. The wheel relief portion has a pair of reinforcement beads extending in a longitudinal direction of the vehicle and projecting from an outer sidewall and an inner sidewall, respectively, of the front side frame into an internal space of the hollow front side frame. The reinforcement beads have top surfaces being in abutment with each other and firmly fixed together.
摘要翻译：一种车辆前体结构，包括具有减小水平宽度的车轮释放部分的闭合横截面结构的中空前侧框架，以允许车辆前轮的旋转运动。车轮释放部分具有沿着车辆的纵向方向延伸的一对加强珠，分别从前侧框架的外侧壁和内侧壁分别突出到中空前侧框架的内部空间中。加强珠具有彼此邻接并牢固地固定在一起的顶表面。

14. 发明申请

US20050077755A1 Front body structure of motor vehicle 失效
标题翻译：汽车前身体结构
公开(公告)号：US20050077755A1
公开(公告)日：2005-04-14
申请号：US10960359
申请日：2004-10-06
申请人： Ken Yasui
发明人： Ken Yasui
IPC分类号： B62D25/08 , B62D25/16
CPC分类号： B62D25/16 , B62D25/084
摘要： In a front body structure including a bulk head 25 for supporting the tip 24 of a hood 16 covering an engine room 18 of a motor vehicle 11 and fenders 27, 27 covering the upper part of front wheels 26, 26, the left and right ends 33, 34 of the bulk head 25, after bent backward of a vehicle body, are connected to the fenders 27, 27 to adjust the shape of the front of the vehicle body by the bulk head 25, and when viewed in a plan, V-shape portions are formed at connecting portions between the ends of the bulk head and the fenders so that each of the V-shape portions is covered with each of eaves 36 extended from the fender and bulk head.
摘要翻译：在包括用于支撑覆盖机动车辆11的发动机室18的罩16的顶端24和覆盖前轮26,26的上部的挡泥板27,27的前部体结构中，左右两端散装头25的后侧33,34与车挡体27,27连接，从而通过散装头25调整车身前部的形状，在平面图中看到V 在散装头和挡泥板的端部之间的连接部分形成有形状部分，以便每个V形部分被从挡泥板和散装头部延伸的每一个屋檐36覆盖。

15. 发明授权

US08653067B2 Pharmaceutical composition for treating Alzheimer's disease 有权
标题翻译：用于治疗阿尔茨海默病的药物组合物
公开(公告)号：US08653067B2
公开(公告)日：2014-02-18
申请号：US12597470
申请日：2008-04-23
申请人： Naotake Kobayashi , Kazuo Ueda , Naohiro Itoh , Gaku Sakaguchi , Akira Kato , Akihiro Hori , Hidekazu Haraguchi , Ken Yasui
发明人： Naotake Kobayashi , Kazuo Ueda , Naohiro Itoh , Gaku Sakaguchi , Akira Kato , Akihiro Hori , Hidekazu Haraguchi , Ken Yasui
IPC分类号： A61K31/554 , A61K31/541 , A61K31/426 , A61K31/506 , C07D417/02 , C07D279/06 , C07D277/18 , C07D239/02
CPC分类号： C07D471/04 , A61K9/0019 , A61K9/1623 , A61K9/2018 , A61K31/426 , A61K31/506 , A61K31/535 , A61K31/54 , A61K31/541 , A61K31/554 , C07D239/14 , C07D265/08 , C07D277/18 , C07D279/06 , C07D281/02 , C07D285/36 , C07D295/155 , C07D295/192 , C07D405/04 , C07D417/04 , C07D417/10 , C07D417/12 , A61K2300/00
摘要： A pharmaceutical composition for treating Alzheimer's disease containing a compound represented by the general formula (I); wherein ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; E is lower alkylene, etc.; X is S, O, or NR1; R1 is a hydrogen atom or lower alkyl; R2a, R2b, R3a, R3b, R4a and R4b are each independently a hydrogen atom, halogen, hydroxy, etc.; n and m are each independently an integer of 0 to 3; n+m is an integer of 1 to 3; and R5 is a hydrogen atom, optionally substituted lower alkyl, etc.; its pharmaceutically acceptable salt, or a solvate thereof as an active ingredient.
摘要翻译：一种用于治疗含有由通式（I）表示的化合物的阿尔茨海默病的药物组合物; 其中环A是任选取代的碳环基团或任选取代的杂环基团; E为低级亚烷基等; X是S，O或NR1; R1是氢原子或低级烷基; R2a，R2b，R3a，R3b，R4a和R4b各自独立地为氢原子，卤素，羟基等; n和m各自独立地为0〜3的整数， n + m为1〜3的整数， R5为氢原子，任意取代的低级烷基等; 其药学上可接受的盐或其溶剂合物作为活性成分。

16. 发明申请

US20120022249A1 AMINODIHYDROTHIAZINE DERIVATIVES 有权
公开(公告)号：US20120022249A1
公开(公告)日：2012-01-26
申请号：US13243971
申请日：2011-09-23
申请人： Naotake KOBAYASHI , Kazuo UEDA , Naohiro ITOH , Shinji SUZUKI , Gaku SAKAGUCHI , Akira KATO , Akira YUKIMASA , Akihiro HORI , Yuji KORIYAMA , Hidekazu HARAGUCHI , Ken YASUI , Yasuhiko KANDA
发明人： Naotake KOBAYASHI , Kazuo UEDA , Naohiro ITOH , Shinji SUZUKI , Gaku SAKAGUCHI , Akira KATO , Akira YUKIMASA , Akihiro HORI , Yuji KORIYAMA , Hidekazu HARAGUCHI , Ken YASUI , Yasuhiko KANDA
IPC分类号： C07D281/02 , C07D417/14 , C07D417/04 , C07D417/12 , C07D279/08 , C07D279/06
CPC分类号： C07D417/14 , A61K9/0019 , A61K9/1623 , A61K9/2018 , A61K31/426 , A61K31/505 , A61K31/506 , A61K31/535 , A61K31/54 , A61K31/541 , A61K31/5415 , A61K31/55 , A61K31/551 , A61K31/554 , C07D239/14 , C07D239/24 , C07D239/42 , C07D265/08 , C07D277/18 , C07D279/06 , C07D279/08 , C07D279/12 , C07D281/02 , C07D405/04 , C07D405/10 , C07D417/04 , C07D417/10 , C07D417/12 , C07D471/04
摘要： A composition having BACE 1 inhibitory activity containing a compound represented by the general formula (I): wherein ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; E is lower alkylene; X is S, O, or NR1; R1 is a hydrogen atom or lower alkyl; R2a, R2b, R3a, R3b, R4a and R4b is each independently a hydrogen atom, halogen, or hydroxy etc.; n and m are each independently an integer of 0 to 3; n+m is an integer of 0 to 3; R5 is a hydrogen atom or substituted lower alkyl; its pharmaceutically acceptable salt, or a solvate thereof.

17. 发明授权

US07048326B2 Front body structure of motor vehicle 失效
标题翻译：汽车前身体结构
公开(公告)号：US07048326B2
公开(公告)日：2006-05-23
申请号：US10960359
申请日：2004-10-06
申请人： Ken Yasui
发明人： Ken Yasui
IPC分类号： B60K7/00
CPC分类号： B62D25/16 , B62D25/084
摘要： In a front body structure including a bulk head 25 for supporting the tip 24 of a hood 16 covering an engine room 18 of a motor vehicle 11 and fenders 27, 27 covering the upper part of front wheels 26, 26, the left and right ends 33, 34 of the bulk head 25, after bent backward of a vehicle body, are connected to the fenders 27, 27 to adjust the shape of the front of the vehicle body by the bulk head 25, and when viewed in a plan, V-shape portions are formed at connecting portions between the ends of the bulk head and the fenders so that each of the V-shape portions is covered with each of eaves 36 extended from the fender and bulk head.
摘要翻译：在包括用于支撑覆盖机动车辆11的发动机室18的罩16的顶端24和覆盖前轮26,26的上部的挡泥板27,27的前部体结构中，左右两端散装头25的后侧33,34与车挡体27,27连接，从而通过散装头25调整车身前部的形状，在平面图中看到V 在散装头和挡泥板的端部之间的连接部分形成有形状部分，以便每个V形部分被从挡泥板和散装头部延伸的每一个屋檐36覆盖。

18. 发明授权

US08585133B2 Vehicle body frame structure 有权
标题翻译：车体框架结构
公开(公告)号：US08585133B2
公开(公告)日：2013-11-19
申请号：US12668596
申请日：2008-07-08
申请人： Shigeto Yasuhara , Yasuhisa Egawa , Ken Yasui
发明人： Shigeto Yasuhara , Yasuhisa Egawa , Ken Yasui
IPC分类号： B62D21/02
CPC分类号： B62D25/2018 , B62D21/11 , B62D25/082
摘要： An automobile vehicle compartment includes an octagonal frame having side sills that extend in the vehicle body fore-and-aft direction, a dashboard lower cross member and middle cross member that extend in the vehicle width direction, and four inclined members, and it is therefore possible to ensure that there is sufficient rigidity both for a collision load from the vehicle body fore-and-aft direction and from the side of the vehicle body, thereby minimizing deformation of the vehicle compartment. Furthermore, since front side frames and a front bumper beam form a U-shaped frame that curves in a U-shape toward the vehicle body fore-and-aft direction in front of the vehicle compartment, it is possible by crushing of the high rigidity U-shaped frame to absorb effectively a collision load from the vehicle body fore-and-aft direction, including an offset collision, thereby preventing more effectively deformation of the vehicle compartment.
摘要翻译：汽车车厢包括具有在车体前后方向上延伸的侧梁的八角形框架，沿车宽方向延伸的仪表板下横梁和中横梁，以及四个倾斜构件，因此可以确保对于来自车体前后方向和车体侧面的碰撞负载都具有足够的刚性，从而最小化车厢的变形。此外，由于前侧框架和前保险杠梁形成在车厢前方朝向车身前后方向呈U字形的U字形框架，因此可以通过破碎高刚性 U形框架有效地吸收来自车身前后方向的碰撞载荷，包括偏移碰撞，从而防止车厢更有效地变形。

19. 发明申请

US20130200653A1 VEHICLE BODY STRUCTURE 有权
标题翻译：车身结构
公开(公告)号：US20130200653A1
公开(公告)日：2013-08-08
申请号：US13878853
申请日：2011-10-26
申请人： Ken Yasui , Hitoshi Mizohata , Eisei Higuchi
发明人： Ken Yasui , Hitoshi Mizohata , Eisei Higuchi
IPC分类号： B62D21/15 , B62D25/20
CPC分类号： B62D21/15 , B62D21/11 , B62D21/155 , B62D25/20
摘要： A vehicle body body includes: left and right floor frames for supporting a floor panel; left and right side-frames extending from the vicinities of ends of the left and right floor frames in the front-rear direction so as to be separated in the front-rear direction of the vehicle body from the left and right floor frames; and a subframe provided below the left and right side-frames. Left and right bulkheads and left and right collar sections of a hollow shape, which are provided to the left and right bulkheads, are provided within the left and right floor frames. The subframe has left and right subframe end sections extending toward end sections of the left and right floor frames. The left and right subframe end sections are connected to the left and right collar sections by left and right connection members so as to be able to swing vertically.
摘要翻译：车体主体包括：用于支撑地板的左右地板框架; 所述左右侧框架从所述左右地板框架的前后方向的端部附近延伸，以使其与所述左右地板框架在所述车体的前后方向上分离; 以及设置在左右侧框架下方的子帧。设置在左右舱壁上的中空形状的左右隔板和左右两个环形部分设置在左右地板框架内。子框架具有向左和右侧地板框架的端部延伸的左右子框架端部部分。左右副车架端部通过左右连接部件与左右的轴环部分连接，以便能够垂直摆动。

20. 发明申请

US20120248820A1 VEHICLE BODY FRONT STRUCTURE 有权
标题翻译：车身身体前部结构
公开(公告)号：US20120248820A1
公开(公告)日：2012-10-04
申请号：US13433899
申请日：2012-03-29
申请人： Ken Yasui , Eisei Higuchi
发明人： Ken Yasui , Eisei Higuchi
IPC分类号： B62D25/08 , B60R19/26
CPC分类号： B62D25/082 , B60R19/34 , B62D21/152
摘要： A vehicle front part structure efficiently absorbs collision energy upon a narrow offset collision in which a collision object, such as an oncoming vehicle, makes a front collision with a vehicle outer side outer than a front side frame, and thereby inhibits the vehicle body front part from moving rearward to the vehicle interior side. The vehicle front part includes a pair of left/right front side frames extending along the longitudinal direction of the vehicle, and a power unit disposed at the longitudinal center between the left/right front side frames. The left/right front side frames beside the power unit include branch frames extending toward the vehicle laterally outer side. The rear end portions of the branch frames penetrate the outer surface of the left/right front side frames and extend along an inner wall. Connection members are provided at the front portions of the left/right front side frames.
摘要翻译：车辆前部结构在碰撞物体（例如迎面而来的车辆）与前侧车架外部的车辆外侧形成前方碰撞的狭窄偏移碰撞时有效地吸收碰撞能量，从而抑制车身前部从向后移动到车辆内侧。车辆前部包括沿着车辆的纵向方向延伸的一对左/右前侧框架和设置在左/右前侧框架之间的纵向中心处的动力单元。动力单元旁边的左/右前侧框架包括向车辆横向外侧延伸的分支框架。分支框架的后端部分穿过左/右前侧框架的外表面并沿着内壁延伸。连接构件设置在左/右前侧框架的前部。

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