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11. 发明申请

US20130289467A1 DRUG ELUTING OCULAR IMPLANT 有权
标题翻译：药物治疗OCOLAR IMPLANT
公开(公告)号：US20130289467A1
公开(公告)日：2013-10-31
申请号：US13989037
申请日：2011-11-22
申请人： David Haffner , Ken Curry , Harold Heitzmann , David Applegate
发明人： David Haffner , Ken Curry , Harold Heitzmann , David Applegate
IPC分类号： A61F9/00 , A61F9/007
CPC分类号： A61F9/0017 , A61F9/00781 , A61F2210/0061 , A61K9/0051 , A61K9/0092 , A61K9/2072
摘要： Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.
摘要翻译：本文公开了用于治疗眼部疾病的药物递送装置和方法，其需要靶向和受控地将药物施用于眼睛的内部以减少或预防病症的症状。这些装置能够控制释放一种或多种药物，并且还可以包括通过允许房水通过装置流出眼睛前房而允许治疗眼内压升高的结构。

12. 发明申请

US20120109040A1 COMBINED TREATMENT FOR CATARACT AND GLAUCOMA TREATMENT 有权
标题翻译：联合治疗卡拉OK和玻璃体治疗
公开(公告)号：US20120109040A1
公开(公告)日：2012-05-03
申请号：US13118338
申请日：2011-05-27
申请人： Gregory T. Smedley , David Haffner , Barbara Niksch , Hosheng Tu , Thomas W. Burns
发明人： Gregory T. Smedley , David Haffner , Barbara Niksch , Hosheng Tu , Thomas W. Burns
IPC分类号： A61F9/007
CPC分类号： A61F9/00781 , A61F9/0017 , A61F9/00736 , A61F9/00754
摘要： A method is provided for treatment of cataract in combination with a glaucoma procedure while maintaining the intraocular pressure by permitting aqueous to flow out of an anterior chamber of the eye through a surgically stented pathway. A trabecular stent is adapted for implantation within the trabecular meshwork of an eye such that intraocular liquid flows controllably from the anterior chamber of the eye to Schlemm's canal, bypassing the trabecular meshwork. Depending upon the specific treatment contemplated, pharmaceuticals may be utilized in conjunction with the trabecular stent enabling post-cataract healing processes.
摘要翻译：提供一种用于治疗与青光眼手术相结合的白内障的方法，同时通过允许水通过手术支架的通路从眼前房流出而保持眼内压。小梁支架适于植入眼睛的小梁网内，使眼内液体从眼睛前房流向Schlemm运河，绕过小梁网。根据预期的具体治疗，可以将药物与小梁支架结合使用，以实现白内障后愈合过程。

13. 发明授权

US08075511B2 System for treating ocular disorders and methods thereof 有权
标题翻译：用于治疗眼部疾病的系统及其方法
公开(公告)号：US08075511B2
公开(公告)日：2011-12-13
申请号：US12111033
申请日：2008-04-28
申请人： Hosheng Tu , Gregory T. Smedley , David Haffner , Barbara A. Niksch
发明人： Hosheng Tu , Gregory T. Smedley , David Haffner , Barbara A. Niksch
IPC分类号： A61M5/00
CPC分类号： A61M27/00 , A61F9/00781
摘要： Systems and methods for treating ocular disorders are disclosed. One system has an implant and a delivery device. The implant has inlet and outlet portions, a lumen extending therebetween and communicating with inlet and outlet ports. The implant is sized so that in use aqueous humor flows from an anterior chamber of an eye through the implant and into a uveal scleral outflow path of the eye. The delivery device is configured to advance the implant from within the anterior chamber, with the outlet portion leading the inlet portion, to a location where the outlet and inlet ports respectively communicate with the uveal scleral outflow path and the anterior chamber. One method involves advancing an implant from within the anterior chamber, and draining fluid from therein such that fluid flows into an implant inlet port and out through an implant outlet port and into the uveal scleral outflow path.
摘要翻译：公开了用于治疗眼部疾病的系统和方法。一个系统具有植入物和递送装置。植入物具有入口和出口部分，在其间延伸并与入口和出口连通的内腔。植入物的大小使得在使用中，房水从眼睛的前房通过植入物流入眼睛的葡萄膜巩膜流出道。输送装置构造成使得植入物从前室中前进，出口部分将入口部分引导到出口和入口分别与葡萄膜巩膜流出道和前房连通的位置。一种方法包括从前房中推进植入物，并从其中排出流体，使得流体流入植入物入口并通过植入物出口并流入葡萄膜巩膜流出道。

14. 发明申请

US20080015488A1 GLAUCOMA IMPLANT WITH DOUBLE ANCHOR MECHANISM 有权
标题翻译：具有双重锚固机构的GLAUCOMA植入物
公开(公告)号：US20080015488A1
公开(公告)日：2008-01-17
申请号：US11860785
申请日：2007-09-25
申请人： Hosheng Tu , Gregory Smedley , Barbara Niksch , David Haffner
发明人： Hosheng Tu , Gregory Smedley , Barbara Niksch , David Haffner
IPC分类号： A61M1/00
CPC分类号： A61F2/16 , A61F9/00781 , A61K9/0048
摘要： The invention relates generally medical devices and methods for the treatment of glaucoma in an animal eye and, more particularly, to medical devices and methods for treating tissue of the trabecular meshwork and/or Schlemm's canal of the eye to restore or rejuvenate a portion or all of the normal physiological function of directing aqueous outflow for maintaining a normal intraocular pressure in the eye.
摘要翻译：本发明一般涉及用于治疗动物眼睛中的青光眼的医疗装置和方法，更具体地，涉及用于治疗小梁网和/或眼睛的施莱姆氏管的组织以恢复或恢复一部分或全部的医疗装置和方法引导水流出的正常生理功能，以维持眼中正常的眼内压。

15. 发明申请

US20070276316A1 DEVICES AND METHODS FOR GLAUCOMA TREATMENT 有权
公开(公告)号：US20070276316A1
公开(公告)日：2007-11-29
申请号：US11836112
申请日：2007-08-08
申请人： David Haffner , Gregory Smedley , Hosheng Tu
发明人： David Haffner , Gregory Smedley , Hosheng Tu
IPC分类号： A61M1/00
CPC分类号： A61F9/00781
摘要： Intraocular stents and applicators are disclosed for treating glaucoma. The stents are configured to extend between the anterior chamber of the eye and Schlemm's canal for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The stents can have features for anchoring the stent into Schlemm's canal as well as preventing the walls of Schlemm's canal from closing the outlet of the stents. The applicators can be steerable so as to make implantation easier. Additionally, the applicators can be configured to hold a plurality of stents so that multiple stents can be implanted through one incision without removing the applicator from the incision between serial implantations.

16. 发明申请

US20070276315A1 DEVICES AND METHODS FOR GLAUCOMA TREATMENT 有权
标题翻译： GLAUCOMA治疗的装置和方法
公开(公告)号：US20070276315A1
公开(公告)日：2007-11-29
申请号：US11836106
申请日：2007-08-08
申请人： David Haffner , Gregory Smedley , Hosheng Tu
发明人： David Haffner , Gregory Smedley , Hosheng Tu
IPC分类号： A61M1/00
CPC分类号： A61F9/00781
摘要： Intraocular stents and applicators are disclosed for treating glaucoma. The stents are configured to extend between the anterior chamber of the eye and Schlemm's canal for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The stents can have features for anchoring the stent into Schlemm's canal as well as preventing the walls of Schlemm's canal from closing the outlet of the stents. The applicators can be steerable so as to make implantation easier. Additionally, the applicators can be configured to hold a plurality of stents so that multiple stents can be implanted through one incision without removing the applicator from the incision between serial implantations.
摘要翻译：公开了用于治疗青光眼的眼内支架和敷贴器。支架构造成在眼前房和施乐姆氏管之间延伸，以增强从前房的水流出，以便降低眼内压。支架可以具有用于将支架锚定到施乐姆运河中的特征，以及阻止施莱姆运河的墙壁关闭支架的出口。施加器可以是可操纵的，以便使植入更容易。此外，施用器可以被配置成保持多个支架，使得可以通过一个切口植入多个支架，而不会从串联注入之间的切口移除施加器。

17. 发明申请

US20060200113A1 Liquid jet for glaucoma treatment 审中-公开
标题翻译：液体射流青光眼治疗
公开(公告)号：US20060200113A1
公开(公告)日：2006-09-07
申请号：US11353854
申请日：2006-02-13
申请人： David Haffner , Hosheng Tu , Gregory Smedley
发明人： David Haffner , Hosheng Tu , Gregory Smedley
IPC分类号： A61B18/18
CPC分类号： A61F9/00781 , A61M5/14
摘要： Methods of treating glaucoma are described including treatment of an eye with a liquid jet. The liquid jet can be generated by a laser-induced liquid jet instrument which is inserted through an incision in an eye. A stent can also be used, the stent having an inflow portion that is in fluid communication with an outflow portion. The stent can be inserted into the eye and transported from the incision through the anterior chamber of the eye toward the trabecular meshwork of the eye. In some embodiments, the stent can be advanced through the anterior chamber of the eye and provide fluid communication between the anterior chamber and Schlemm's canal. The method includes infusing fluid into an aqueous cavity and increasing the pressure of the fluid within the aqueous cavity.
摘要翻译：描述治疗青光眼的方法，包括用液体射流治疗眼睛。液体射流可以通过激光诱导的液体喷射器产生，其通过眼睛中的切口插入。还可以使用支架，所述支架具有与流出部分流体连通的流入部分。支架可以插入眼睛，并从切口通过眼睛的前房转移到眼睛的小梁网。在一些实施例中，支架可以推进穿过眼睛的前房并且在前房和施莱姆氏管之间提供流体连通。该方法包括将流体输入水腔并增加水腔内的流体的压力。

18. 发明申请

US20050266047A1 Injectable glaucoma implants with multiple openings 有权
公开(公告)号：US20050266047A1
公开(公告)日：2005-12-01
申请号：US11083713
申请日：2005-03-18
申请人： Hosheng Tu , Jason Artof , David Haffner
发明人： Hosheng Tu , Jason Artof , David Haffner
IPC分类号： A61F2/00 , A61F9/007 , A61K31/215
CPC分类号： A61F9/00781 , A61F9/0017 , A61F2220/0008 , A61F2230/0069 , A61F2250/0067 , A61K31/215
摘要： Intraocular stents and applicators are disclosed for treating glaucoma. The stents are configured to extend between the anterior chamber of the eye and Schlemm's canal for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The stents can have features for anchoring the stent into Schlemm's canal as well as preventing the walls of Schlemm's canal from closing the outlet of the stents. The applicators can be steerable so as to make implantation easier. Additionally, the applicators can be configured to hold a plurality of stents so that multiple stents can be implanted through one incision without removing the applicator from the incision between serial implantations.

19. 发明授权

US08506515B2 Uveoscleral shunt and methods for implanting same 有权
标题翻译：血管巩膜分流术及其植入方法
公开(公告)号：US08506515B2
公开(公告)日：2013-08-13
申请号：US11938238
申请日：2007-11-09
申请人： Thomas W. Burns , David Haffner , Harold A. Heitzmann , Todd N. Fjield , Richard A. Hill
发明人： Thomas W. Burns , David Haffner , Harold A. Heitzmann , Todd N. Fjield , Richard A. Hill
IPC分类号： A61M5/00
CPC分类号： A61F9/00781
摘要： Devices and methods for treating intraocular pressure are disclosed. The devices include shunts for draining aqueous humor from the anterior chamber to the uveoscleral outflow pathway, including the supraciliary space and the suprachoroidal space. The shunts are preferably implanted by ab interno procedures.
摘要翻译：公开了用于治疗眼内压的装置和方法。这些装置包括用于将房水从前房排出至经视神经流出途径的分流器，包括上腔空间和脉络膜上空间。分流器优选通过ab内部程序植入。

20. 发明申请

US20120078362A1 DRUG ELUTING OCULAR IMPLANT 审中-公开
标题翻译：药物治疗OCOLAR IMPLANT
公开(公告)号：US20120078362A1
公开(公告)日：2012-03-29
申请号：US13321144
申请日：2010-05-18
申请人： David Haffner , Ken Curry , Harold Heitzmann , David Applegate
发明人： David Haffner , Ken Curry , Harold Heitzmann , David Applegate
IPC分类号： A61F2/16
CPC分类号： A61F9/0017 , A61F9/00781 , A61F2210/0004 , A61F2250/0068 , A61K9/0051
摘要： Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allows for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.
摘要翻译：本文公开了用于治疗眼部疾病的药物递送装置和方法，其需要靶向和受控地将药物施用于眼睛的内部以减少或预防病症的症状。该装置能够控制释放一种或多种药物，并且还可以包括允许通过使装置从眼睛前房流出房水来治疗眼内压升高的结构。

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