专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

US20220057406A1 CHEMICAL DETECTION ASSAYS 有权
公开(公告)号：US20220057406A1
公开(公告)日：2022-02-24
申请号：US17271077
申请日：2019-08-22
申请人： Richard C. Willson , Victoria M. Hlavinka , Binh V. Vu , Federico Augusto Ruiz-Ruiz , Marco Antonio Rito Palomares , Mary A. Crum
发明人： Richard C. Willson , Victoria M. Hlavinka , Binh V. Vu , Federico Augusto Ruiz-Ruiz , Marco Antonio Rito Palomares , Mary A. Crum
IPC分类号： G01N33/66 , C12Q1/32 , G01N33/72 , C12Q1/54 , G01N21/76
摘要： Disclosed are methods and kits for analyzing a sample comprising 1,5-anhydroglucitol and a possible first analyte via one or more chemiluminescent reactions. Certain embodiments include measuring a first light response resulting from a first chemiluminescent reaction and measuring a second light response resulting from a second chemiluminescent reaction. Certain embodiments also include comparing the first light response to the second light response to determine a ratio of 1,5-anhydroglucitol and the first analyte. Also provided are kits including reagents for practicing the claimed methods.

12. 发明申请

US20150324518A1 Genetic Affinity of Microorganisms and Viruses 审中-公开
标题翻译：微生物和病毒的遗传亲和力
公开(公告)号：US20150324518A1
公开(公告)日：2015-11-12
申请号：US13532001
申请日：2012-06-25
申请人： George E. Fox , Richard C. Willson, III , Zhengdong Zhang
发明人： George E. Fox , Richard C. Willson, III , Zhengdong Zhang
IPC分类号： G06F19/14 , H01J49/16
CPC分类号： G16B10/00 , G16B20/00 , G16B25/00 , H01J49/164
摘要： Selecting which sub-sequences in a database of nucleic acid such as 16S rRNA are highly characteristic of particular groupings of bacteria, microorganisms, fungi, etc. on a substantially phylogenetic tree. Also applicable to viruses comprising viral genomic RNA or DNA. A catalogue of highly characteristic sequences identified by this method is assembled to establish the genetic identity of an unknown organism. The characteristic sequences are used to design nucleic acid hybridization probes that include the characteristic sequence or its complement, or are derived from one or more characteristic sequences. A plurality of these characteristic sequences is used in hybridization to determine the phylogenetic tree position of the organism(s) in a sample. Those target organisms represented in the original sequence database and sufficient characteristic sequences can identify to the species or subspecies level. Oligonucleotide arrays of many probes are especially preferred. A hybridization signal can comprise fluorescence, chemiluminescence, or isotopic labeling, etc.; or sequences in a sample can be detected by direct means, e.g. mass spectrometry. The method's characteristic sequences can also be used to design specific PCR primers. The method uniquely identifies the phylogenetic affinity of an unknown organism without requiring prior knowledge of what is present in the sample. Even if the organism has not been previously encountered, the method still provides useful information about which phylogenetic tree bifurcation nodes encompass the organism.
摘要翻译：选择核酸数据库（如16S rRNA）中的哪些子序列在基本系统发育树上是细菌，微生物，真菌等的特定分组的高度特征。也适用于包含病毒基因组RNA或DNA的病毒。组合通过该方法鉴定的高度特征性序列的目录，以确定未知生物体的遗传特性。特征序列用于设计核酸杂交探针，其包括特征序列或其补体，或衍生自一个或多个特征序列。在杂交中使用多个这些特征序列来确定样品中生物的系统发生树位置。在原始序列数据库中表示的目标生物体和足够的特征序列可以鉴定物种或亚种水平。许多探针的寡核苷酸阵列是特别优选的。杂交信号可以包括荧光，化学发光或同位素标记等; 或样品中的序列可以通过直接方式检测，例如，质谱。该方法的特征序列也可用于设计特异性PCR引物。该方法唯一地识别未知生物的系统发生亲和力，而不需要事先了解样品中存在的内容。即使生物体以前没有遇到，该方法仍然提供关于哪个系统发生树分叉节点包含有机体的有用信息。

13. 发明申请

US20140141175A1 VIBRATION DAMPING COATING 审中-公开
标题翻译：振动阻尼涂料
公开(公告)号：US20140141175A1
公开(公告)日：2014-05-22
申请号：US13925072
申请日：2013-06-24
申请人： Robert W. Willson , Michael C. Willson , John P. Henderson
发明人： Robert W. Willson , Michael C. Willson , John P. Henderson
IPC分类号： C23D5/00 , B05D1/10
CPC分类号： C23D5/00 , B05D1/10 , C03C8/20 , C04B35/486 , C04B2235/3225 , C04B2235/36 , C04B2235/365 , C23C4/02 , C23C4/06 , C23C4/11 , C23C4/134 , C23C28/3215 , C23C28/324 , C23C28/3455 , Y02T50/67
摘要： A method is disclosed for applying a vibration-damping surface to an article. The method includes providing a coating material comprising a ceramic, metallic or cermet material and a viscoelastic glass frit and plasma spraying the coating material onto an article. The coating material forms a plurality of ceramic, metallic or cermet microstructures having voids with the viscoelastic glass frit distributed to interact with the voids to provide vibration damping. Also disclosed are plasma spray coatings for damping vibrations that includes a ceramic-glass frit composite coating capable of reducing resonant vibrations in a substrate at temperatures between 700° F. to 1500° F. and said plasma spray coating as a coating on a substrate.
摘要翻译：公开了一种将减振表面施加到制品上的方法。该方法包括提供包括陶瓷，金属或金属陶瓷材料和粘弹性玻璃料的涂层材料和等离子体将涂层材料喷涂到制品上。涂层材料形成多个具有空隙的陶瓷，金属或金属陶瓷微结构，其中分布有粘弹性玻璃料以与空隙相互作用以提供振动阻尼。还公开了用于阻尼振动的等离子体喷涂涂层，其包括陶瓷 - 玻璃料复合涂层，其能够在700°F至1500°F之间的温度下降低衬底中的共振振动，并将所述等离子喷涂涂层作为衬底上的涂层。

14. 发明授权

US07727775B2 Optical microlabels: shapes and reflectors 失效
标题翻译：光学微标签：形状和反射镜
公开(公告)号：US07727775B2
公开(公告)日：2010-06-01
申请号：US11257566
申请日：2005-10-25
申请人： Richard C. Willson , Paul Ruchhoeft
发明人： Richard C. Willson , Paul Ruchhoeft
IPC分类号： G01N15/06 , G01N21/00 , G01N21/76 , G01N33/53 , G01N33/543 , G01N33/551 , G01N33/553 , C12Q1/00 , C12M1/34 , C12M3/00
CPC分类号： G01N33/54373 , B82Y5/00 , C12Q1/6837 , Y10S436/805 , Y10S977/701 , Y10S977/702 , Y10S977/704 , Y10S977/705 , Y10S977/773 , Y10S977/774 , Y10S977/834 , Y10S977/92 , C12Q2563/155
摘要： Labels and methods of producing labels for use in clinical, analytical and pharmaceutical development assays are provided. Labels may comprise shape-encoded particles which may be coupled to ligands such as DNA, RNA and antibodies, where different shapes are used to identify which ligand(s) are present. Labels may also comprise reflectors, including retroreflectors and retroreflectors susceptible to analyte-dependent assembly for efficient homogeneous assays.
摘要翻译：提供了生产用于临床，分析和药物开发测定的标签的标签和方法。标签可以包括可以与诸如DNA，RNA和抗体的配体偶联的形状编码的颗粒，其中使用不同的形状来鉴定哪些配体存在。标签还可以包括反射器，包括对分析物依赖性装配易于进行有效均匀测定的后向反射器和后向反射器。

15. 发明申请

US20080095878A1 Imprint Lithography Template Having a Feature Size Under 250 nm 审中-公开
标题翻译：具有250nm以下特征尺寸的版画光刻模板
公开(公告)号：US20080095878A1
公开(公告)日：2008-04-24
申请号：US11760855
申请日：2007-06-11
申请人： Todd Bailey , Byung Choi , Matthew Colburn , S.V. Sreenivasan , C. Willson , John Ekerdt
发明人： Todd Bailey , Byung Choi , Matthew Colburn , S.V. Sreenivasan , C. Willson , John Ekerdt
IPC分类号： B29C59/02
CPC分类号： G11B5/855 , B29C35/0888 , B29C37/0053 , B29C43/003 , B29C2035/0827 , B29C2043/025 , B82Y10/00 , B82Y40/00 , G03F7/0002 , G03F9/00 , Y10S977/887
摘要： The present invention includes a template comprising a plurality of protrusions and a plurality of recessions with a distance between a zenith of any of the plurality of protrusions and a nadir of any one of the plurality of recessions being less than 250 nm.
摘要翻译：本发明包括一个模板，其包括多个突起和多个凹陷，多个凹陷之间的距离在多个突起中的任一个的顶点之间的距离和多个凹陷中的任一个的最低点之间小于250nm。

16. 发明申请

US20060261518A1 Use of step and flash imprint lithography for direct imprinting of dielectric materials for dual damascene processing 失效
标题翻译：使用步进和闪光压印光刻技术直接刻印用于双镶嵌加工的介质材料
公开(公告)号：US20060261518A1
公开(公告)日：2006-11-23
申请号：US11363071
申请日：2006-02-27
申请人： C. Willson , Frank Palmieri , Yukio Nishimura , Stephen Johnson , Michael Stewart
发明人： C. Willson , Frank Palmieri , Yukio Nishimura , Stephen Johnson , Michael Stewart
IPC分类号： B29C59/02 , B29C35/08 , B28B11/08
CPC分类号： H01L21/76817 , B82Y10/00 , B82Y40/00 , G03F7/0002 , H01L21/76807 , H01L21/76828
摘要： In some embodiments, the present invention is directed to methods that involve the combination of step-and-flash imprint lithography (SFIL) with a multi-tier template to simultaneously pattern multiple levels of, for example, an integrated circuit device. In such embodiments, the imprinted material generally does not serve or act as a simple etch mask or photoresist, but rather serves as the insulation between levels and lines, i.e., as a functional dielectric material. After imprinting and a multiple step curing process, the imprinted pattern is filled with metal, as in dual damascene processing. Typically, the two printed levels will comprise a “via level,” which is used to make electrical contact with the previously patterned under-level, and a “wiring level.” The present invention provides for the direct patterning of functional materials, which represents a significant departure from the traditional approach to microelectronics manufacturing.
摘要翻译：在一些实施例中，本发明涉及涉及步进和快速压印光刻（SFIL）与多层模板的组合以同时对例如集成电路器件的多个级别进行图案化的方法。在这样的实施例中，压印材料通常不起到或用作简单的蚀刻掩模或光致抗蚀剂的作用，而是用作层和线之间的绝缘，即功能介电材料。在印迹和多步固化过程之后，印刷图案充满金属，如在双镶嵌加工中。通常，两个印刷电平将包括用于与先前图案化的欠电平进行电接触的“通孔电平”和“接线电平”。本发明提供了功能材料的直接图案化，其代表了与传统的微电子制造方法的显着不同。

17. 发明授权

US06630111B1 Apparatus for testing catalysts using spectroscopy 有权
标题翻译：使用光谱测试催化剂的装置
公开(公告)号：US06630111B1
公开(公告)日：2003-10-07
申请号：US09613879
申请日：2000-07-10
申请人： Richard C. Willson, III
发明人： Richard C. Willson, III
IPC分类号： G01N3110
CPC分类号： G01N31/10 , B01J19/0046 , B01J2219/00286 , B01J2219/00315 , B01J2219/00364 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00659 , B01J2219/00691 , B01J2219/00704 , B01J2219/00745 , B01J2219/00747 , C40B30/08 , C40B40/18 , Y10T436/214 , Y10T436/24
摘要： Apparatus for evaluating catalysts, including a multicell holder, e.g., a honeycomb or plate, or a collection of individual support particles, is treated with solutions/suspensions of catalyst ingredients to produce cells, spots or pellets holding each of a variety of combinations of the ingredients, is dried, calcined or treated as necessary to stabilize the ingredients in the cells, spots or pellets, then is contacted with a potentially reactive feed stream or batch, e.g., biochemical, gas oil, hydrogen plus oxygen, propylene plus oxygen, CCl2F2 and hydrogen, etc. The reaction occurring in each cell can be measured, e.g., by infrared thermography, spectroscopic detection of products or residual reactants, or by sampling, e.g., multistreaming through low volume tubing, from the vicinity of each combination, followed by analysis, e.g., spectral analysis, chromatography, etc., or by observing temperature change in the vicinity of the catalyst, e.g., by thermographic techniques, to determine the relative efficacy of the catalysts in each combination. Robotic techniques can be employed in producing the cells, spots, pellets, etc.
摘要翻译：用于评价催化剂的装置，包括多单元保持器，例如蜂窝或板，或各个支撑颗粒的集合，用催化剂成分的溶液/悬浮液处理，以产生保持各种各样的组合的细胞，斑点或颗粒成分，干燥，煅烧或处理以稳定细胞，斑点或丸粒中的成分，然后与潜在的反应性进料流或批次接触，例如生化，瓦斯油，氢加氧，丙烯加氧，CCl 2 F 2 和氢气等。可以测量每个电池中发生的反应，例如通过红外热成像，产物或残余反应物的光谱检测，或通过从每个组合的附近采样，例如通过低体积管进行多流，然后是分析，例如光谱分析，色谱等，或通过观察催化剂附近的温度变化，例如通过热成像技术来阻止在每种组合中我们的催化剂的相对功效。机器人技术可用于生产细胞，斑点，丸粒等。

18. 发明授权

US06333196B1 Catalyst testing process and apparatus 有权
标题翻译：催化剂测试过程和设备
公开(公告)号：US06333196B1
公开(公告)日：2001-12-25
申请号：US09499956
申请日：2000-02-08
申请人： Richard C. Willson, III
发明人： Richard C. Willson, III
IPC分类号： G01N3110
CPC分类号： G01N31/10 , B01J19/0046 , B01J2219/00286 , B01J2219/00315 , B01J2219/00364 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00659 , B01J2219/00691 , B01J2219/00704 , B01J2219/00745 , B01J2219/00747 , C40B30/08 , C40B40/18 , Y10T436/214 , Y10T436/24
摘要： Apparatus for testing catalyst candidates including a multicell holder e.g. a honeycomb or plate, or a collection of individual support particles that have been treated with solutions/suspensions of catalyst ingredients to produce cells, spots or pellets holding each of a variety of combinations of the ingredients and dried, calcined or treated as necessary to stabilize the ingredients in the cells, spots or pellets. The apparatus also includes structure for contacting the catalyst candidates with a potentially reactive feed stream or batch e.g., biochemical, gas oil, hydrogen plus oxygen, propylene plus oxygen, CCl2F2 and hydrogen, etc. The reaction occurring in each cell can be measured, e.g. by infrared thermography, spectroscopic detection of products or residual reactants, or by sampling, e.g. by multistreaming through low volume tubing, from the vicinity of each combination, followed by analysis e.g. spectral analysis, chromatography etc, or by observing temperature change in the vicinity of the catalyst e.g. by thermographic techniques, to determine the relative efficacy of the catalysts in each combination. Robotic techniques can be employed in producing the cells, spots, pellets, etc.
摘要翻译：用于测试催化剂候选物的装置，包括多单元载体蜂窝或板，或已经用催化剂成分的溶液/悬浮液处理的单独的载体颗粒的集合，以产生保持成分的各种组合的各种组分的细胞，斑点或颗粒，并根据需要进行干燥，煅烧或处理以稳定细胞中的成分，斑点或颗粒。该装置还包括使催化剂候选物与潜在的反应性进料流或批料例如生化，瓦斯油，氢加氧，丙烯加氧，CCl 2 F 2和氢等接触的结构。通过红外热像仪，产物或残余反应物的光谱检测，或通过采样，例如，通过低体积管道从每个组合的附近进行多流，然后进行分析。光谱分析，色谱分析等，或者通过观察催化剂附近的温度变化。通过热成像技术确定催化剂在每种组合中的相对功效。机器人技术可用于生产细胞，斑点，丸粒等。

19. 发明授权

US5185585A Crystal oscillator and method with amplitude and phase control 失效
标题翻译：晶体振荡器和幅度和相位控制方法
公开(公告)号：US5185585A
公开(公告)日：1993-02-09
申请号：US756847
申请日：1991-09-10
申请人： Gerald R. Newell , Michael W. Nootbaar , Pradeep Bhardwaj , Robert C. Willson
发明人： Gerald R. Newell , Michael W. Nootbaar , Pradeep Bhardwaj , Robert C. Willson
IPC分类号： H03B5/38 , H03L5/00
CPC分类号： H03L5/00 , H03B5/38
摘要： Crystal oscillator and method which in one embodiment have a crystal element connected in a positive feedback loop with a charge amplifier and an integrator, with the gain of the loop being maintained at a level of unity. Compensation is provided to offset the effects of shunt capacitance in the crystal element, and precise phase control is maintained around the loop. In other embodiments, a crystal element is connected in a series feedback loop with a buffer amplifier, and operation is provided by maintaining the oscillation signal at level at which distortion, clipping, and saturation do not occur. Compensation for shunt capacitance across the crystal element is provided by applying a compensation signal which is equal in amplitude but opposite in phase to the signal passing through the shunt capacitance to the input terminal of the buffer amplifier to cancel the effect of the shunt capacitance. Compensation is also provided to cancel interfering crosstalk signals between oscillators in systems with more than one oscillator.
摘要翻译：在一个实施例中，晶体振荡器和方法具有以正反馈环路与电荷放大器和积分器连接的晶体元件，其中环路的增益保持在一个一致的水平。提供补偿以抵消晶体元件中分流电容的影响，并且在环路周围保持精确的相位控制。在其他实施例中，晶体元件与缓冲放大器串联反馈环路连接，并且通过将振荡信号保持在不发生失真，限幅和饱和的电平来提供操作。通过施加一个补偿信号来提供晶体元件两端的分流电容的补偿，该补偿信号的幅度相等，与通过分流电容的信号相反地与缓冲放大器的输入端相反，以消除并联电容的影响。还提供补偿以消除具有多个振荡器的系统中的振荡器之间的干扰串扰信号。

20. 发明授权

US4136662A Wood burning stove 失效
标题翻译：木燃烧炉
公开(公告)号：US4136662A
公开(公告)日：1979-01-30
申请号：US836502
申请日：1977-09-26
申请人： Allan C. Willson
发明人： Allan C. Willson
IPC分类号： F24B1/02 , F24B5/02 , F24B7/02 , F24B13/00 , F24C1/14
CPC分类号： F24B13/004 , F24B1/02 , F24B5/023 , F24B7/02
摘要： A wood burning stove is formed with double front and rear side walls of heat conductive metal interconnected by heat conductive spacer fins and providing air passageways by which room air is heated by conduction from the walls which are heated by the burning of wood deposited on a firebox grate made up of spaced bricks supported by metal holders secured in heat conducting relation to said inner side walls. The rear side air passageway is divided into central and outer vertical sections the central one of which is closed at the bottom end and communicates with the atmosphere through an opening in the outer wall intermediate its vertical ends and with the stove interior above the firebox and below the grate through openings in the inner wall intermediate its vertical ends and adjacent its bottom end, respectively. A vertical baffle between these inner and outer walls separates said intermediate openings from each other, and a thermostatically controlled damper associated with the opening in the outer wall controls the amount of room air delivered either under the firebox grate or above it. The front side air passageway is divided into upper and lower sections separated by a viewing box closed at its outer end by a glass window and removably closed at its inner end by a pair of hinged doors.
摘要翻译：木燃烧炉形成有导热金属的双前壁和后侧壁，其通过导热间隔件翅片相互连接，并提供空气通道，室内空气通过壁传导而被加热，这些壁被沉积在火箱上的木材的燃烧加热格栅由隔开的砖支撑，金属支架被固定成与所述内侧壁导热的热量。后侧空气通道被分成中部和外部垂直部分，其中心部分在底部处封闭，并通过位于其垂直端部之间的外壁中的开口与火炉内部的炉内部以及下方连通内壁上的格栅通过开口分别位于其垂直端部和其底端附近。这些内壁和外壁之间的垂直挡板将所述中间开口彼此隔开，并且与外壁中的开口相关联的恒温控制的阻尼器控制在火箱格栅或其上方输送的室内空气的量。前侧空气通道被分为上部和下部，它们由在其外端由玻璃窗封闭的观察箱分开，并且在其内端由一对铰链门可拆卸地封闭。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式