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11. 发明授权

US08101244B2 Apparatus and method for producing or processing a product or sample 有权
标题翻译：用于生产或加工产品或样品的装置和方法
公开(公告)号：US08101244B2
公开(公告)日：2012-01-24
申请号：US11148822
申请日：2005-06-09
申请人： Allan J. Clarke , David George Doughty , Frederick H. Fiesser
发明人： Allan J. Clarke , David George Doughty , Frederick H. Fiesser
IPC分类号： B05C11/10
CPC分类号： B05C11/10 , G01N21/95684
摘要： An apparatus and method are provided for producing a plurality of products or processing a plurality of samples via dispensing. The apparatus and method provide real-time monitoring of the products/samples and can provide real-time control. The apparatus and method can monitor the liquid both before and after it has been added to a carrier substrate. The apparatus and method can provide monitoring of each product/sample that is processed.
摘要翻译：提供了用于生产多个产品或通过分配来处理多个样品的装置和方法。该设备和方法提供对产品/样品的实时监控，并可提供实时控制。该装置和方法可以在添加到载体基板之前和之后监测液体。该装置和方法可以提供对处理的每个产品/样品的监测。

12. 发明申请

US20080185121A1 HORIZONTAL, UNDERNEATH MOTORCYCLE HEAT EXCHANGER 审中-公开
标题翻译：水平，水下摩托车热交换器
公开(公告)号：US20080185121A1
公开(公告)日：2008-08-07
申请号：US11834351
申请日：2007-08-06
申请人： ALLAN J. CLARKE
发明人： ALLAN J. CLARKE
IPC分类号： F28F1/10 , B62K11/00 , F01M5/00
CPC分类号： F28D1/04 , B62K11/04 , F01M5/002 , F28D2001/028 , F28D2021/0089 , F28D2021/0092
摘要： The present invention is a heat exchanger for a motorcycle which is adapted to be installed on the motorcycle in a substantially horizontal orientation. Also, the present invention is a heat exchanger for a motorcycle which is adapted to be installed on the motorcycle beneath the engine and/or beneath the crankcase and/or beneath the oil pan and/or beneath the gearbox. Preferably, the heat exchanger is made with finned tubular core elements. At the location under the motorcycle, the thinness of the heat exchanger is important, so preferably it is made with thin hollow plates. Preferably, the heat exchanger is installed in a suspended maimer beneath the motorcycle, so that cooling air may pass effectively over its top and bottom surfaces. Preferably, the heat exchanger is an oil intercooler.
摘要翻译：本发明是一种用于摩托车的热交换器，其适于以基本上水平的方向安装在摩托车上。另外，本发明是一种用于摩托车的热交换器，其适于安装在发动机下方和/或曲轴箱下方的摩托车和/或油盘下方和/或齿轮箱下方。优选地，热交换器由翅片管状芯元件制成。在摩托车下的位置，热交换器的薄度是重要的，因此优选地由薄的中空板制成。优选地，热交换器被安装在摩托车下方的悬挂式破碎机中，使得冷却空气可以有效地在其顶部和底部表面上通过。优选地，热交换器是油中间冷却器。

13. 发明授权

US07163693B1 Multi-component pharmaceutical dosage form 失效
标题翻译：多组分药物剂型
公开(公告)号：US07163693B1
公开(公告)日：2007-01-16
申请号：US10049227
申请日：2000-07-27
申请人： Allan J Clarke , Teodoro Fonio , Geoffrey Arthur Harris , Ron Kift , Donald Lightfoot , Shane McGinley , Thomas Ofsharick , Margaret Mary Szymczack
发明人： Allan J Clarke , Teodoro Fonio , Geoffrey Arthur Harris , Ron Kift , Donald Lightfoot , Shane McGinley , Thomas Ofsharick , Margaret Mary Szymczack
IPC分类号： A61K9/48
CPC分类号： A61J3/07 , A61K9/4808
摘要： A multi-component pharmaceutical dosage form comprising a plurality of drug substance-containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form by a weld between parts of the assembled dosage form.
摘要翻译：一种多组分药物剂型，其包含多个含药物的子单元，为包含含有药物的聚合物的固体基质的胶囊隔室和/或固体亚单元，所述子单元连接在一起组装的剂型通过组装的剂型的部分之间的焊接。

14. 发明授权

US08986777B2 Vapor sheath for liquid dispensing nozzle 有权
标题翻译：液体分配喷嘴的蒸气鞘
公开(公告)号：US08986777B2
公开(公告)日：2015-03-24
申请号：US13389457
申请日：2010-08-11
申请人： Allan J. Clarke , Frederick H. Fiesser , James A. McHugh
发明人： Allan J. Clarke , Frederick H. Fiesser , James A. McHugh
IPC分类号： B05D1/02 , B05D5/00 , B05B15/02 , A61M11/00
CPC分类号： B05B15/02 , A61M11/00 , B05B15/50 , B05B15/55 , B05D1/02
摘要： The present disclosure provides a device for preventing the fouling of a liquid dispensing nozzle. The end of the dispensing nozzle is placed in a hollow interior of a band carrying the same solvents that are dispensed by the nozzle. The solvent on the band evaporates into a gap between the ring and dispensing nozzle, thus providing a vapor sheath or environment that helps to prevent the fouling of the dispensing nozzle.
摘要翻译：本公开提供了一种用于防止液体分配喷嘴的结垢的装置。分配喷嘴的端部放置在携带由喷嘴分配的相同溶剂的带的中空内部。带上的溶剂蒸发到环和分配喷嘴之间的间隙中，从而提供有助于防止分配喷嘴结垢的蒸气鞘或环境。

15. 发明授权

US08967074B2 Vapor sheath for liquid dispensing nozzle 有权
标题翻译：液体分配喷嘴的蒸气鞘
公开(公告)号：US08967074B2
公开(公告)日：2015-03-03
申请号：US12854566
申请日：2010-08-11
申请人： Allan J. Clarke , Frederick H. Fiesser , James A. McHugh
发明人： Allan J. Clarke , Frederick H. Fiesser , James A. McHugh
IPC分类号： B05B7/00 , B05B15/02 , A61M11/00
CPC分类号： B05B15/02 , A61M11/00 , B05B15/50 , B05B15/55 , B05D1/02
摘要： The present disclosure provides a device for preventing the fouling of a liquid dispensing nozzle. The end of the dispensing nozzle is placed In a hollow interior of a band carrying the same solvents that are dispensed by the nozzle. The solvent on the band evaporates into a gap between the ring and the dispensing nozzle, thus providing a vapor sheath or environment that helps to prevent the fouling of the dispensing nozzle.
摘要翻译：本公开提供了一种用于防止液体分配喷嘴的结垢的装置。分配喷嘴的末端被放置在携带由喷嘴分配的相同溶剂的带的中空内部。带上的溶剂蒸发到环和分配喷嘴之间的间隙中，从而提供有助于防止分配喷嘴结垢的蒸气鞘或环境。

16. 发明授权

US07883721B2 Pharmaceutical formulation 有权
标题翻译：药物制剂
公开(公告)号：US07883721B2
公开(公告)日：2011-02-08
申请号：US10470438
申请日：2002-01-30
申请人： Stephen Mark McAllister , Ronald K. Raby, Jr. , Adrian Brown , Allan J. Clarke , Wayne Matthews , Daniel N. Margetson
发明人： Stephen Mark McAllister , Ronald K. Raby, Jr. , Adrian Brown , Allan J. Clarke , Wayne Matthews , Daniel N. Margetson
IPC分类号： A61K9/48
CPC分类号： A61K9/4808 , A61K9/4816
摘要： The present invention is directed to pharmaceutically acceptable polymeric compositions suitable for injection molding of single or multi-component pharmaceutical dosage forms comprising a plurality of drug substance containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form by a weld between parts of the assembled dosage form.
摘要翻译：本发明涉及适于注射模塑单组分或多组分药物剂型的药学上可接受的聚合物组合物，其包含多个含药物物质的子单元，包括胶囊隔室和/或包含固体基质的固体亚单元含有药物的聚合物，所述子单元通过组装的剂型的部分之间的焊接在组装的剂型中连接在一起。

17. 发明申请

US20100221292A1 INJECTION MOLDING PROCESS FOR THE PREPARATION OF AN ORAL DELIVERY DEVICE FOR THE PHARMACEUTICALLY ACTIVE AGENT 有权
标题翻译：用于制备药物活性剂的口服递送装置的注射成型方法
公开(公告)号：US20100221292A1
公开(公告)日：2010-09-02
申请号：US12627330
申请日：2009-11-30
申请人： Allan J. Clarke , Robert Glinecke , Ronald Raby , Chi Leung Li , Luigi Martini
发明人： Allan J. Clarke , Robert Glinecke , Ronald Raby , Chi Leung Li , Luigi Martini
IPC分类号： A61K9/00 , B29C45/00
CPC分类号： A61K9/2072 , A61K9/0004 , A61K9/284 , A61K9/2893 , B29C45/14065 , B29C45/14073 , B29C2045/14122 , B29C2045/14155 , B29K2105/0035
摘要： An injection moulding process for the preparation of an oral delivery device comprising a core which contains a pharmaceutically active agent, having a coating with one or more openings leading to such a core. The invention also relates to devices produced by the process, and to injection moulds suitable for performing the process.
摘要翻译：一种用于制备口服递送装置的注射模制方法，所述口腔递送装置包含含有药物活性剂的核心，所述药物活性剂具有具有通向所述核心的一个或多个开口的涂层。本发明还涉及通过该方法生产的装置，以及适用于执行该方法的注射模具。

18. 发明申请

US20120141655A1 VAPOR SHEATH FOR LIQUID DISPENSING NOZZLE 有权
标题翻译：用于液体分配喷嘴的蒸气浴
公开(公告)号：US20120141655A1
公开(公告)日：2012-06-07
申请号：US13389457
申请日：2010-08-11
申请人： Allan J. Clarke , Frederick H. Fiesser , James A. McHugh
发明人： Allan J. Clarke , Frederick H. Fiesser , James A. McHugh
IPC分类号： B05D1/02 , B05D5/00
CPC分类号： B05B15/02 , A61M11/00 , B05B15/50 , B05B15/55 , B05D1/02
摘要： The present disclosure provides a device for preventing the fouling of a liquid dispensing nozzle. The end of the dispensing nozzle is placed in a hollow interior of a band carrying the same solvents that are dispensed by the nozzle. The solvent on the band evaporates into a gap between the ring and dispensing nozzle, thus providing a vapor sheath or environment that helps to prevent the fouling of the dispensing nozzle.
摘要翻译：本公开提供了一种用于防止液体分配喷嘴的结垢的装置。分配喷嘴的端部放置在携带由喷嘴分配的相同溶剂的带的中空内部。带上的溶剂蒸发到环和分配喷嘴之间的间隙中，从而提供有助于防止分配喷嘴结垢的蒸气鞘或环境。

19. 发明授权

US08123509B2 Injection molding process for the preparation of an oral delivery device for the pharmaceutically active agent 有权
标题翻译：用于制备用于药物活性剂的口服递送装置的注射成型方法
公开(公告)号：US08123509B2
公开(公告)日：2012-02-28
申请号：US12627330
申请日：2009-11-30
申请人： Allan J. Clarke , Robert Glinecke , Ronald Raby , Chi Leung Li , Luigi Martini
发明人： Allan J. Clarke , Robert Glinecke , Ronald Raby , Chi Leung Li , Luigi Martini
IPC分类号： B29C45/14
CPC分类号： A61K9/2072 , A61K9/0004 , A61K9/284 , A61K9/2893 , B29C45/14065 , B29C45/14073 , B29C2045/14122 , B29C2045/14155 , B29K2105/0035
摘要： An injection molding process for the preparation of an oral delivery device comprising a core which contains a pharmaceutically active agent, having a coating with one or more openings leading to such a core. The invention also relates to devices produced by the process, and to injection molds suitable for performing the process.
摘要翻译：一种用于制备口服递送装置的注射模制方法，所述口腔递送装置包含含有药物活性剂的核心，所述药物活性剂具有具有通向所述核心的一个或多个开口的涂层。本发明还涉及通过该方法生产的装置，以及适用于执行该方法的注射模具。

20. 发明授权

US08122849B2 Apparatus and method for producing a pharmaceutical product 有权
标题翻译：用于生产药物的装置和方法
公开(公告)号：US08122849B2
公开(公告)日：2012-02-28
申请号：US11148894
申请日：2005-06-09
申请人： Allan J. Clarke , David George Doughty , Frederick H Fiesser , David Tainsh , Dwight Walker , David Wagner
发明人： Allan J. Clarke , David George Doughty , Frederick H Fiesser , David Tainsh , Dwight Walker , David Wagner
IPC分类号： C23C16/52 , B05C11/10 , A61K9/28
CPC分类号： B05C11/10 , A61J3/00 , A61J3/005 , A61J3/007 , A61J3/10 , B41P2200/00 , B41P2200/31 , C23C16/52 , G01N21/3563 , G01N21/359 , G01N21/64 , G01N21/93 , G01N21/9508 , G01N2021/6417 , Y10T436/11 , Y10T436/113332 , Y10T436/12 , Y10T436/2575
摘要： An apparatus and method are provided for producing pharmaceutical and pharmaceutical-like products. The apparatus and method provide real-time monitoring of the pharmaceutical product and can provide real-time control. The apparatus and method can monitor the dosage both before and after it has been added to a carrier substrate. The apparatus and method can provide monitoring of each pharmaceutical product that is processed.
摘要翻译：提供了用于生产药物和药物样产品的装置和方法。该装置和方法提供药物产品的实时监测并可提供实时控制。该装置和方法可以在添加到载体基质之前和之后监测剂量。该装置和方法可以提供对所加工的每种药物的监测。

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