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    • 13. 发明授权
    • Method for making a biodegradable adhesive for soft living tissue
    • 制造软生物体组织的生物降解性粘合剂的方法
    • US4804691A
    • 1989-02-14
    • US90861
    • 1987-08-28
    • James P. EnglishGerald W. McNeelyRichard L. Dunn
    • James P. EnglishGerald W. McNeelyRichard L. Dunn
    • A61L24/04C08G18/42C09J175/06C08G18/30
    • C09J175/06A61L24/046C08G18/4277C08G18/428C08G2230/00Y10S528/905
    • A method for making an adhesive for use in joining soft living tissue including the steps of preparing a hydroxyl-terminated polyester by reacting a biodegradable monomer with a polyhydroxy polymerization initiator in the presence of an amount up to about 2.0 weight percent of a catalyst, and then preparing a diisocyanate-terminated prepolymer adhesive by reacting about 24 to 92 weight percent of the hydroxy-terminated polyester with about 8 to 76 weight percent excess aromatic diisocyante. The polyester and the diisocyanate are preferably dissolved in an organic solvent prior to the mixture thereof in a ratio of solids to solvent of about 60:40. The polyester is a polymer or copolymer of lactide, glycolide or .epsilon.-caprolactone. The initiator is ethylene glycol, diethylene glycol, pentaerythritol or 1,1,1-tris (hydroxymethyl) ethane. The catalyst is stannous octoate, a zinc compound, an aliphatic tertiary amine, dibutyltin diacetate or 1,4-diazabicyclo [2,2,2] octane.
    • 一种制造用于连接软性生物体组织的粘合剂的方法,其包括通过使可生物降解的单体与多羟基聚合引发剂在至多约2.0重量%的催化剂的量存在下反应制备羟基封​​端的聚酯的步骤,以及 然后通过使约24至92重量%的羟基封端的聚酯与约8至7​​6重量%的过量芳族二异氰酸酯反应制备二异氰酸酯封端的预聚物粘合剂。 聚酯和二异氰酸酯优选在固体与溶剂的比例为约60:40的混合物之前溶解在有机溶剂中。 聚酯是丙交酯,乙交酯或ε-己内酯的聚合物或共聚物。 引发剂是乙二醇,二甘醇,季戊四醇或1,1,1-三(羟甲基)乙烷。 催化剂为辛酸亚锡,锌化合物,脂族叔胺,二乙酸二丁基锡或1,4-二氮杂双环[2,2,2]辛烷。
    • 15. 发明授权
    • Ventilation tube permitting two-way gaseous communication with one-way
liquid valve
    • 通气管允许与单向液体阀双向气体连通
    • US4568337A
    • 1986-02-04
    • US601310
    • 1984-04-17
    • Richard W. Treharne, IIIAnthony D. Prescott
    • Richard W. Treharne, IIIAnthony D. Prescott
    • A61F11/00A61B19/00
    • A61F11/002Y10T137/791
    • A myringotomy tube allowing two-way gaseous communication between an external ear canal and a middle ear cavity and only one-way liquid communication from the middle ear cavity to the external ear canal includes a ball mounted within the tube to move freely into and out of contact with a valve seat for preventing liquid from flowing into the middle ear cavity. When fluid is present in the external ear canal, fluid pressure operates to move the ball into contact with the valve seat to provide a positive seal against ingress of fluid. In the absence of fluid within the external ear canal, the ball is free to move away from the seat to permit pressure equalization and liquid drainage from the middle ear to the outer ear. Longitudinal openings are provided in the portion of the tube within the external ear canal to facilitate free passage of fluid past the ball.
    • 允许在外耳道和中耳腔之间进行双向气体连通并且仅从中耳腔到外耳道的单向液体连通的鼓膜切开管包括安装在管内以自由进入和离开 与阀座接触以防止液体流入中耳腔。 当流体存在于外耳道中时,流体压力操作以将球移动到与阀座接触以提供抵抗流体进入的正密封。 在外耳道内没有液体的情况下,球可自由移动离开座椅,以允许压力平衡和从中耳到外耳的液体排液。 在外耳道内的管部分提供纵向开口以便于流体自由通过球。
    • 17. 发明授权
    • Middle ear ventilating tube
    • 中耳通气管
    • US4744792A
    • 1988-05-17
    • US693155
    • 1985-01-22
    • Thomas W. SanderKaren Krygier
    • Thomas W. SanderKaren Krygier
    • A61F11/00A61F2/18
    • A61F11/002
    • A ventilation tube is provided for permitting gaseous communication between the middle ear and the outer ear canal of a recipient. The tube is formed of a material that resists extrusion from the tympanic membrane such as titanium or a titanium alloy or others, and includes an outer end portion which is adapted to communicate with the outer ear canal and an inner ear portion adapted to communicate with the middle ear. A pair of spaced apart flanges are mounted respectively on the outer end portion and the inner end portion of the tube. A coating or insert formed of a material that resists tissue adherence such as a fluoroplastic polymer (e.g., Teflon) or others lines at least the portion of the opening in the tube adjacent to the middle ear and the flange on the middle ear side of the tympanic membrane.
    • 提供通气管,用于允许接受者的中耳和外耳道之间的气体连通。 管由抗体从诸如钛或钛合金等的鼓膜挤出的材料形成,并且包括适于与外耳道连通的外端部和适于与外耳道连通的内耳部 中耳。 一对间隔开的凸缘分别安装在管的外端部分和内端部分上。 由抵抗组织粘附的材料形成的涂层或插入物,例如氟塑料聚合物(例如,特氟纶)或其它管线至少与中耳相邻的管中的开口的部分和中耳的中耳侧的凸缘 鼓膜。