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171. 发明申请

US20090311733A1 Enrichment Unit for Biological Components and an Enrichment Method 有权
标题翻译：生物成分富集单位及浓缩方法
公开(公告)号：US20090311733A1
公开(公告)日：2009-12-17
申请号：US12085898
申请日：2006-12-04
申请人： Matti Korpela , Tytti Miettinen , Tuija Tenhunen , Teemu Korpimäki , Pekka Mattsson , Mika Tuomola
发明人： Matti Korpela , Tytti Miettinen , Tuija Tenhunen , Teemu Korpimäki , Pekka Mattsson , Mika Tuomola
IPC分类号： C12Q1/02 , C12M1/00 , C12M1/34 , C12N1/20
CPC分类号： G01N33/54326 , B03C1/01 , B03C1/286 , C12M47/02 , C12M47/04 , G01N1/40 , G01N35/0098
摘要： A biological component enrichment unit for the isolation, purification and/or determination of a biological component using particles (3) and/or another solid phase, which enrichment unit comprises at least one sample container (1, 15, 26, 32, 39) for the realisation of the biological sample method. The enrichment unit comprises a lead-through structure (5), such as a bushing (21, 27) made up of one or several parts or a cover having one or several openings (25, 36). The lead-through structure and one or several sample containers can be brought into connection with one another so that, when the lead-through structure is placed on top of the sample container, a functional unit is formed for the realisation of the biological method, such as for the binding of the component, the growing, isolation, purification, enrichment of the bacteria or cell or for another similar method.
摘要翻译：一种用于使用颗粒（3）和/或另一种固相分离，纯化和/或测定生物组分的生物组分富集单元，所述富集单元包括至少一个样品容器（1,15,26,32,39）用于实现生物样本法。浓缩单元包括一个引导结构（5），例如由一个或多个部分构成的衬套（21,27）或具有一个或多个开口（25,36）的盖子。引线结构和一个或多个样品容器可以彼此连接，使得当引线结构放置在样品容器的顶部时，形成用于实现生物学方法的功能单元，例如组分的结合，细菌或细胞的生长，分离，纯化，富集或另外类似的方法。

172. 发明申请

US20090277834A1 RESIN CONTACTOR AND CONTAINMENT SYSTEM 有权
标题翻译：树脂接触器和容纳系统
公开(公告)号：US20090277834A1
公开(公告)日：2009-11-12
申请号：US11721430
申请日：2005-12-15
申请人： Gregory Mark Vero , Colin Bruce Ritchie , Abigail Holmquist
发明人： Gregory Mark Vero , Colin Bruce Ritchie , Abigail Holmquist
IPC分类号： C02F1/42
CPC分类号： B01J47/006 , B01J20/28009 , B01J47/016 , B01J47/10 , B01J49/00 , B03C1/286 , C02F1/42 , C02F1/488
摘要： The invention provides a method for contacting liquid with an ion exchange resin comprising introducing liquid into a process tank containing ion exchange resin at an inlet (2) and removing liquid that has been contacted with resin from the process tank at an outlet, the outlet being located above the inlet (2), the process tank including a resin containment region (7, 9) disposed between the inlet (2) and the outlet to impede the upward flow of the resin as it becomes entrained in the liquid flowing from the inlet to the outlet, and a contactor region for promoting contact between the resin and the liquid located below the containment region (7, 9), said containment region (7, 9) containing an array of settling members through which the liquid and resin upflow and which impede the flow of the resin to a sufficient extent that it is substantially contained within or below the containment region (7, 9). Apparatus for performing this method is also provided.
摘要翻译：本发明提供了一种使液体与离子交换树脂接触的方法，包括在入口（2）将含有离子交换树脂的液体引入到处理罐中，并且在出口处除去已经与处理罐接触树脂的液体，出口是位于入口（2）上方，处理罐包括设置在入口（2）和出口之间的树脂容纳区域（7,9），以阻止树脂在从入口流出的液体中夹带时向上流动以及用于促进树脂和位于容纳区域（7,9）下方的液体之间的接触的接触器区域，所述容纳区域包括沉降构件阵列，液体和树脂向上流动和这阻碍了树脂的流动到足以使其基本上包含在容纳区域（7,9）内或下方的流动。还提供了用于执行该方法的设备。

173. 发明申请

US20090277157A1 APPARATUS FOR IMPROVING FUEL EFFICIENCY AND REDUCING EMISSIONS IN FOSSIL-FUEL BURNING ENGINES 审中-公开
标题翻译：提高燃油效率和减少燃油燃烧发动机排放的装置
公开(公告)号：US20090277157A1
公开(公告)日：2009-11-12
申请号：US12116495
申请日：2008-05-07
申请人： Ken Martin , Lin Xiao
发明人： Ken Martin , Lin Xiao
IPC分类号： F01N3/00
CPC分类号： B03C1/286 , B03C1/0332 , B03C2201/18 , B03C2201/30 , F02M27/045 , F02M37/22
摘要： A system for realizing improved fuel efficiency and reduced fuel emissions in an internal combustion engine. The system comprises a nano-jet filter includes a fuel channeling chamber having a set of aligned magnetic members such that the flow of fuel passes through a magnetic field created by the set of aligned magnetic members. The system further comprises a nano-jet saver, having a chamber equipped with additional sets of magnets in order to magnetize larger fuel molecules and traverse hyper magnet gradients. The purpose of using a hyper magnetic field is to change conventional fuel into “nano” fuel. Having fuel particles with a smaller diameter, both better fuel efficiency and reduced emissions are achieved as the fuel burns more completely and more cleanly. With any fossil-fuel internal-combustion engine, an operator can expect to see a reduction in emissions to the environment, fuel savings, and better performance while using an apparatus that consumes no external energy.
摘要翻译：一种用于实现燃料效率提高和减少内燃机燃料排放的系统。该系统包括纳米喷射过滤器，其包括具有一组对准的磁性构件的燃料通道腔，使得燃料流通过由该组对准的磁性构件产生的磁场。该系统还包括纳米喷射保护器，其具有配备有额外的磁体组的室，以便磁化较大的燃料分子并穿过超磁体梯度。使用超磁场的目的是将常规燃料改变为“纳米”燃料。具有较小直径的燃料颗粒，当燃料更完全和更干净地燃烧时，实现更好的燃料效率和减少的排放。使用任何化石燃料内燃机，运营商可以期望在使用不消耗外界能量的设备的同时，减少对环境的排放，节省燃料和提高性能。

174. 发明申请

US20090272694A1 APPARATUS AND METHOD FOR SEPARATION MAGNETIC PARTICLES FROM A SOLUTION 审中-公开
标题翻译：从解决方案中分离磁性颗粒的装置和方法
公开(公告)号：US20090272694A1
公开(公告)日：2009-11-05
申请号：US12501676
申请日：2009-07-13
申请人： Steven T. Krueger
发明人： Steven T. Krueger
IPC分类号： B03C1/02
CPC分类号： B03C1/286 , B03C2201/18
摘要： A biological sample processing apparatus and method of use thereof. The biological sample processing apparatus includes a rod-shaped magnet having a north pole, a south pole, a length and a width, and a plunger covering the magnet. The north pole and the south pole of the rod-shaped magnet are substantially orthogonal to the length of the rod-shaped magnet. The apparatus separates magnetic particles from a solution containing, for example, a biological sample.
摘要翻译：一种生物样品处理装置及其使用方法。生物样品处理装置包括具有北极，南极，长度和宽度的棒状磁体和覆盖磁体的柱塞。棒状磁体的北极和南极基本上与棒状磁体的长度正交。该装置将磁性颗粒与含有例如生物样品的溶液分离。

175. 发明授权

US07611435B2 Power transfer assembly with gasket having magnet 有权
标题翻译：带磁铁的垫片的动力传递组件
公开(公告)号：US07611435B2
公开(公告)日：2009-11-03
申请号：US11804046
申请日：2007-05-16
申请人： Kevin R. Beutler
发明人： Kevin R. Beutler
IPC分类号： F16H57/04 , F01M11/03
CPC分类号： B03C1/286 , F16H48/08 , F16H57/02 , F16H57/029 , F16H57/031 , F16H57/0404 , F16H57/0483 , F16H2057/02052
摘要： An axle assembly for a vehicle includes a housing, a differential assembly rotatably supported within the housing, a differential cover and a gasket assembly positioned between the housing and the differential cover. The gasket assembly includes a body and a magnet coupled to the body. The magnet is positioned in communication with a lubricant located within the interior of the housing.
摘要翻译：用于车辆的车轴组件包括壳体，可旋转地支撑在壳体内的差速器组件，差速器盖和位于壳体和差速器盖之间的垫圈组件。垫圈组件包括主体和联接到主体的磁体。磁体定位成与位于壳体内部的润滑剂连通。

176. 发明授权

US07597520B2 Apparatus and method for transferring samples from a source to a target 失效
标题翻译：将样本从源传送到目标的装置和方法
公开(公告)号：US07597520B2
公开(公告)日：2009-10-06
申请号：US11311558
申请日：2005-12-19
申请人： Hans-Jörg Zobel , Gerard William Leeman , Amir Porat , Moshe Gombinsky
发明人： Hans-Jörg Zobel , Gerard William Leeman , Amir Porat , Moshe Gombinsky
IPC分类号： G01N37/497
CPC分类号： G01N35/10 , B03C1/286 , G01N35/04
摘要： A transfer unit for transferring a sample from a source vessel to a target vessel. The transfer unit includes a transfer device having a pin tip with a central bore terminating at a bottom wall, an actuating element movably disposed in the pin tip bore, an actuator rod for moving the actuating element and a compensating device connected between the actuating element and the actuator rod. The actuator rod moves the actuating element between a first position adjacent the tip bottom wall and a second position away from the bottom wall. Movement of the actuating element causes a sample in proximity to the pin tip to be alternately collected and released from the pin tip. Such movement also defines a stroke length for the actuator rod, wherein the compensating device compensates for any variations in the actuator rod stroke length. The transfer unit further includes a tip ejector for removing the disposable tips from the transfer device and a tip loading station for applying the tips to the transfer device.
摘要翻译：用于将样品从源容器转移到目标容器的转移单元。传送单元包括具有销末端的传送装置，其中心孔终止在底壁处，可移动地设置在销尖孔中的致动元件，用于移动致动元件的致动杆和连接在致动元件和执行器杆。致动器杆将致动元件移动到与尖端底壁相邻的第一位置和远离底壁的第二位置之间。致动元件的运动导致靠近销尖的样品交替地从销尖收集和释放。这种运动还限定了致动器杆的行程长度，其中补偿装置补偿致动器杆行程长度中的任何变化。传送单元还包括用于从传送装置移除一次性尖端的尖端喷射器和用于将尖端施加到传送装置的尖端装载站。

177. 发明申请

US20090181359A1 METHOD OF PERFORMING ULTRA-SENSITIVE IMMUNOASSAYS 审中-公开
标题翻译：执行超敏感免疫法的方法
公开(公告)号：US20090181359A1
公开(公告)日：2009-07-16
申请号：US11923828
申请日：2007-10-25
申请人： Sheng C. Lou , Kurt H. Chau
发明人： Sheng C. Lou , Kurt H. Chau
IPC分类号： C12Q1/70 , G01N33/553 , G01N33/53
CPC分类号： C12Q1/6804 , B03C1/01 , B03C1/286 , B03C2201/18 , B03C2201/26 , C12Q1/703 , C12Q2563/143 , C12Q2563/131 , C12Q2563/125
摘要： A method for improving the sensitivity of an immunoassay by a factor of at least 10 to about 25, and perhaps greater. Furthermore, in addition to increasing the sensitivity of the assay, the method of this invention also improves assay specificity. In order to match or improve upon sensitivity of 0.2 pg/mL for an analyte, this invention provides an immunoassay involving amplification of a signal, e.g., a chemiluminescent signal, a specific binding member, e.g., a monoclonal antibody, and microparticle separation, e.g., magnetic microparticle separation, from large volumes of sample (e.g., from about 0.2 to about 3 mL). Such an immunoassay can be carried out with an automated immunoassay analyzers, e.g., an automated immunoassay analyzer in the ARCHITECT® family of analyzers.
摘要翻译：将免疫测定的灵敏度提高至少10至25，甚至更大的方法。此外，除了增加测定的灵敏度之外，本发明的方法还提高了测定特异性。为了匹配或提高分析物的0.2pg / mL的灵敏度，本发明提供了涉及扩增信号的免疫测定，例如化学发光信号，特异性结合成员，例如单克隆抗体和微粒分离，例如，磁性微粒分离，从大量样品（例如，约0.2至约3mL）。这样的免疫测定可以用自动化免疫分析仪进行，例如在分析仪系列中的自动化免疫测定分析仪。

178. 发明授权

US07504032B2 Filter device 有权
标题翻译：过滤装置
公开(公告)号：US07504032B2
公开(公告)日：2009-03-17
申请号：US11812847
申请日：2007-06-22
申请人： Minoru Tashiro
发明人： Minoru Tashiro
IPC分类号： B03C1/02
CPC分类号： B01D35/06 , B03C1/032 , B03C1/286 , B03C2201/18
摘要： A filter device has a filter tank into which a contaminated fluid is introduced, a magnetic ball filter medium using a large number of metal balls, magnets, and lift rods. The magnetic ball filter medium is formed of an aggregate of a large number of spherical metal balls of a magnetic material and is held in a filter medium storage portion in a manner such that the metal balls are movable relatively to one another. The magnets are movable between a first position and a second position. When in the first position, the magnets apply a magnetic field to the metal balls, thereby causing the metal balls magnetically to attract one another and so that the metal balls are fixed to one another. When in the second position, the magnetic attraction between the metal balls is canceled so that the metal balls are movable.
摘要翻译：过滤装置具有被引入污染流体的过滤罐，使用大量金属球，磁铁和提升杆的磁球过滤介质。磁球过滤器介质由大量的磁性材料的球形金属球的聚集体形成，并且以使得金属球相对于彼此移动的方式被保持在过滤介质存储部中。磁体可在第一位置和第二位置之间移动。当处于第一位置时，磁体对金属球施加磁场，从而使金属球磁力相互吸引，使得金属球彼此固定。当处于第二位置时，金属球之间的磁吸引力被消除，使得金属球是可移动的。

179. 发明申请

US20080296237A1 FLUID PROCESSING APPARATUS AND METHODS 审中-公开
标题翻译：流体加工装置及方法
公开(公告)号：US20080296237A1
公开(公告)日：2008-12-04
申请号：US12189264
申请日：2008-08-11
申请人： John M. Hammond
发明人： John M. Hammond
IPC分类号： B01D36/00 , B01D37/04
CPC分类号： B01D35/06 , B03C1/286 , B03C2201/18
摘要： A fluid processing apparatus and method are provided for filtering a fluid from a source and delivering a filtrate derived therefrom to a first destination, and delivering a decantate derived therefrom to a second destination. The fluid separation and delivery apparatus for the method comprises a filter device having an inlet port for connecting to a fluid source, a first outlet port for directing filtrate to a first destination, and a second outlet port for directing decantate to a second destination.
摘要翻译：提供了一种流体处理装置和方法，用于过滤来自源的流体并将其产生的滤液输送到第一目的地，并将从其获得的倾析物输送到第二目的地。用于该方法的流体分离和输送装置包括具有用于连接到流体源的入口端口和用于将滤液引导到第一目的地的第一出口端口和用于引导滗向第二目的地的第二出口端口的过滤装置。

180. 发明申请

US20080277348A1 Liquid Exchange Method, Ingredient Extraction Method Using the Same, Composite Container and Autoanalyzer 审中-公开
标题翻译：液体交换方法，使用它的成分萃取方法，复合容器和自动分析仪
公开(公告)号：US20080277348A1
公开(公告)日：2008-11-13
申请号：US11886188
申请日：2006-05-22
申请人： Yuji Izumizawa
发明人： Yuji Izumizawa
IPC分类号： B03C1/02 , G01N33/20
CPC分类号： B03C1/286 , B01L3/502 , B01L2200/0647 , B01L2300/0803 , B01L2300/0809 , B01L2300/087 , B01L2400/043 , B03C1/284 , B03C2201/18 , G01N33/54333 , G01N35/0098
摘要： A liquid exchange method of exchanging liquids present around a magnetic substance is provided. The method serves to prevent a remaining liquid from transferring to a next step and a loss of the magnetic substance. Even when the liquid exchange method is applied to an autoanalyzer, the device structure will not be complicated. A vessel 11 in which a liquid 16 containing a magnetic substance 15, a vessel 12 containing a liquid 17, a magnetic substance move-mediating member 13 and also a magnet 18 are prepared. The magnet 18 is disposed at the exterior of the vessel 11, and the magnet 18 is moved to move the magnetic substance 15 on the inner wall face of the vessel 11 in order to take out the magnetic substance 15 from the magnetic substance containing liquid 16, to move the magnetic substance 15 from the inner wall face of the vessel 11 to the surface of the magnetic substance move-mediating member 13, and to move to the inner wall face of the other vessel 12 via the magnetic substance move-mediating member 13 so as to introduce the magnetic substance 15 into the liquid 17 in the vessel 12, thereby exchanging the liquids present around the magnetic substance 15.
摘要翻译：提供了一种交换存在于磁性物质周围的液体的液体交换方法。该方法用于防止剩余液体转移到下一步骤和磁性物质的损失。即使将液体交换方法应用于自动分析仪，装置结构也不复杂。制备容器11，其中容纳有磁性物质15的液体16，容纳液体17的容器12，磁性物质移动介质构件13和磁体18。磁体18设置在容器11的外部，磁体18被移动以将磁性物质15移动到容器11的内壁面上，以便从含磁性物质的液体16中取出磁性物质15 将磁性物质15从容器11的内壁面移动到磁性物质移动介质构件13的表面，并且经由磁性物质移动介质构件移动到另一容器12的内壁面以便将磁性物质15引入容器12中的液体17中，从而交换存在于磁性物质15周围的液体。

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