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151. 发明授权

US4963313A Balloon catheter 失效
标题翻译：气球导管
公开(公告)号：US4963313A
公开(公告)日：1990-10-16
申请号：US126769
申请日：1987-11-30
申请人： Richard A. Noddin , Arthur R. Madenjian , Ralph J. Barry, Jr.
发明人： Richard A. Noddin , Arthur R. Madenjian , Ralph J. Barry, Jr.
IPC分类号： A61L29/06 , A61M25/00 , A61M29/02
CPC分类号： A61M25/1029 , A61L29/06 , A61M25/104
摘要： An inflatable medical balloon is formed by fabricating a tubular preform having a tapered region at the end of the portion where the main body of the balloon will form to enable the corresponding transition section of the blown balloon to have a separately controllable thickness profile. The preferred method includes providing a tube of a selected resin of wall thickness and diameter suitable for being formed into a balloon, and selectively heating to drawing temperature a defined region of the tube at one or both ends of the portion of the tube from which the balloon is to be formed. Tension is applied in opposite directions to respective ends of the heated region to draw the region to a smaller diameter, thereby providing a preform having, at the end of the portion of the tube, a tapered, relatively small diameter region of material that has substantially no crystallization or molecular orientation. In preferred embodiments a tapered region is provided at both ends of the portion in which the main body of the balloon is to be formed. Thereafter the tubular preform is heated to blowing temperature and, while heated, a balloon is formed by drawing and blowing the preform including the tapered regions. The balloon is mounted to form a balloon catheter device. A dilatation balloon catheter, is also described having wall thickness in the transition region less than 0.001 inch.

152. 发明授权

US4283447A Radiopaque polyurethane resin compositions 失效
标题翻译：不透射线的聚氨酯树脂组合物
公开(公告)号：US4283447A
公开(公告)日：1981-08-11
申请号：US108393
申请日：1979-12-28
申请人： Vincent J. Flynn
发明人： Vincent J. Flynn
IPC分类号： A61B19/00 , A61F2/00 , A61L29/04 , A61L29/06 , A61L29/18 , A61M25/00 , A61M25/01 , B29C47/06 , C08K5/101 , C08L75/04 , F16L9/00 , F16L11/00
CPC分类号： A61L29/06 , A61L29/049 , A61L29/18 , A61M25/0009 , A61M25/0041 , A61M25/0045 , A61M25/0108 , B29C47/0023 , B29C47/065 , B29C47/261 , C08K5/101 , C08L75/04 , A61B90/39 , A61F2210/0019 , B29L2031/7542 , Y10T428/139
摘要： Radiopaque compositions are provided by formulating polyurethane resins, alone, or combined with vinyl resins, with alkyl or alkoxyalkyl 2,5-diiodobenzoates, 2,3,4,6-tetraiodobenzoates or mixtures thereof. The compositions are useful in the manufacture of X-ray opaque medical devices, particularly medical surgical tubing. Surgical tubing with excellent plastic memory is provided, well adapted to forming flares and curved tips necessary for selective renal and celial arteriography. Multi-wall and co-tapered multiwall tubing constructions are also disclosed.
摘要翻译：不透射线组合物通过单独或与乙烯基树脂组合的聚氨酯树脂与2,5-二碘苯甲酸烷基或烷氧基烷基酯，2,3,4,6-四碘苯甲酸酯或其混合物配制来提供。该组合物可用于制造X射线不透明医疗装置，特别是医用手术管。提供具有优异塑性记忆的手术管，适用于形成选择性肾和髂动脉造影所需的耀斑和弯曲的尖端。还公开了多壁和共锥形多壁管道结构。

153. 发明授权

US4250072A Radiopaque polyurethane resin compositions 失效
标题翻译：不透射线的聚氨酯树脂组合物
公开(公告)号：US4250072A
公开(公告)日：1981-02-10
申请号：US40278
申请日：1979-05-18
申请人： Vincent J. Flynn
发明人： Vincent J. Flynn
IPC分类号： A61B19/00 , A61F2/00 , A61L29/04 , A61L29/06 , A61L29/18 , A61M25/00 , A61M25/01 , B29C47/06 , C08K5/101 , C08L75/04 , C08K5/09 , C08K5/10
CPC分类号： A61L29/06 , A61L29/049 , A61L29/18 , A61M25/0009 , A61M25/0041 , A61M25/0045 , A61M25/0108 , B29C47/0023 , B29C47/065 , B29C47/261 , C08K5/101 , C08L75/04 , A61B90/39 , A61F2210/0019 , B29L2031/7542
摘要： Radiopaque compositions are provided by formulating polyurethane resins, alone, or combined with vinyl resins, with alkyl or alkoxyalkyl 2,5-diiodobenzoates, 2,3,4,6-tetraiodobenzoates or mixtures thereof. The compositions are useful in the manufacture of X-ray opaque medical devices, particularly medical surgical tubing. Surgical tubing with excellent plastic memory is provided, well adapted to forming flares and curved tips necessary for selective renal and celial arteriography. Multi-wall and co-tapered multiwall tubing contructions are also disclosed.
摘要翻译：不透射线组合物通过单独或与乙烯基树脂组合的聚氨酯树脂与2,5-二碘苯甲酸烷基或烷氧基烷基酯，2,3,4,6-四碘苯甲酸酯或其混合物配制来提供。该组合物可用于制造X射线不透明医疗装置，特别是医用手术管。提供具有优异塑性记忆的手术管，适用于形成选择性肾和髂动脉造影所需的耀斑和弯曲的尖端。还公开了多壁和共锥形多壁管道引导。

154. 发明授权

US3638649A Implantable prosthetic pass-through device 失效
标题翻译：可伸缩的前置通行设备
公开(公告)号：US3638649A
公开(公告)日：1972-02-01
申请号：US3638649D
申请日：1969-07-07
申请人： UNIV MINNESOTA
发明人： ERSEK ROBERT A
IPC分类号： A61L29/06 , A61M1/00 , A61M1/36 , A61M39/10 , A61M25/00
CPC分类号： A61M39/0247 , A61L29/06 , A61M1/3655 , A61M2039/0261 , C08L83/04
摘要： An implantable through-the-skin prosthetic device for the permanent entry into the body for passage of liquid, conductors or the like. The device includes a roughened synthetic resinous member that courses through the skin and subcutaneous tissues and into the body. This special roughening promotes tissue ingrowth and thus effects a firm mechanical seal. Animal experimentation and clinical success imply that the seal is also dry and germproof. One form of such a device is an arteriovenous shunt for use in artificial dialysis. A roughened plastic cannula passes through the skin into the blood vessel itself. A ball joint fitting for connection to the external circuits allows for one-handed operation by a trained patient. A special reamer is provided for use with the shunt.
摘要翻译：一种植入式皮肤修复装置，用于永久地进入体内以通过液体，导体等。该装置包括粗糙的合成树脂构件，其通过皮肤和皮下组织进入身体。这种特殊的粗糙度促进组织向内生长，从而影响机械密封。动物实验和临床成功意味着密封也是干燥和防菌的。这种装置的一种形式是用于人造透析的动静脉分流装置。粗糙的塑料套管穿过皮肤进入血管本身。用于连接到外部电路的球形接头配件允许受过训练的患者单手操作。提供一种特殊的铰刀用于分流器。

155. 发明授权

US3460975A Tack-free silicone rubber articles for medical use 失效
标题翻译：无医用硅橡胶制品
公开(公告)号：US3460975A
公开(公告)日：1969-08-12
申请号：US3460975D
申请日：1965-11-15
申请人： DOW CORNING
发明人： STEBLETON LEO F
IPC分类号： A61F2/00 , A61L27/28 , A61L29/06 , A61L29/08 , C07D311/08 , C08G77/58 , C08J7/04 , C09D185/00 , C09D185/02 , B44D1/22 , C09D3/36
CPC分类号： C08J7/047 , A61F2/00 , A61L27/28 , A61L29/06 , A61L29/08 , A61L29/085 , C07D311/08 , C08G77/58 , C08J2383/04 , C08J2483/00 , C09D185/00 , C09D185/02 , Y10S623/926 , C08L83/04

156. 发明公开

US20240382656A1 Drug Coatings for Medical Devices 审中-公开
公开(公告)号：US20240382656A1
公开(公告)日：2024-11-21
申请号：US18696308
申请日：2021-10-05
申请人： Bard Peripheral Vascular, Inc.
发明人： Jeffrey Wang , Cyal Lecy , Michaella Kavanagh , Logan Grace , Emily Goel , Dillon Mir
IPC分类号： A61L29/16 , A61L29/00 , A61L29/06 , A61L31/00 , A61L31/06 , A61L31/16
CPC分类号： A61L29/16 , A61L29/005 , A61L29/06 , A61L31/005 , A61L31/06 , A61L31/16 , A61L2300/204 , A61L2300/416 , A61L2300/63
摘要： The present disclosure concerns drug coating layers for medical devices that cover an exterior surface or portion thereof. The drug coating layers include a bioabsorbable material with a therapeutic or a polymer microparticle loaded with a therapeutic embedded therein. As the material is bioabsorbed the therapeutic is released and available to provide localized activity in a subject. In some aspects, the drug coating layer is of a material that due to the body temperature of the subject becomes tacky and allows for adhesion to the vessel wall.

157. 发明授权

US12054564B2 Medical device and method for manufacturing same 有权
公开(公告)号：US12054564B2
公开(公告)日：2024-08-06
申请号：US17674891
申请日：2022-02-18
申请人： TERUMO KABUSHIKI KAISHA
发明人： Masanori Kuramoto , Narumi Yokote
IPC分类号： C08F16/30 , A61L29/04 , A61L29/06 , A61L29/14 , A61L31/04 , A61L31/06 , A61L31/14 , A61M25/00
CPC分类号： C08F16/30 , A61L29/041 , A61L29/06 , A61L29/14 , A61L31/048 , A61L31/06 , A61L31/14 , A61M25/0009 , A61L2400/10
摘要： A medical device includes: a substrate layer; an adhesive layer on at least a part of the substrate layer and containing a hydrophilic copolymer (1) containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group; and a surface lubricious layer formed on at least a part of the adhesive layer and containing a hyaluronic acid or a salt thereof and a hydrophilic copolymer (2).

158. 发明授权

US11998663B2 Polytetrafluoroethylene tube and medical tube using same 有权
公开(公告)号：US11998663B2
公开(公告)日：2024-06-04
申请号：US18222174
申请日：2023-07-14
申请人： Junkosha Inc.
发明人： Masamichi Takahashi , Ayumi Matsuda , Koichiro Yoshioka
IPC分类号： A61L29/06 , A61L29/04
CPC分类号： A61L29/06 , A61L29/041
摘要： The present invention provides a thin-walled PTFE tube with appropriate elongation, sufficient strength, and good uniformity during stretching and a medical tube with excellent flexibility and dimensional accuracy. The polytetrafluoroethylene tube according to the present invention is a polytetrafluoroethylene tube having a wall thickness of about 0.04 mm or less, wherein the wetting tension of either of or both outer and inner surfaces of the polytetrafluoroethylene tube is 46 mN/m or more, and in a stress-strain curve obtained by a tensile test performed under an atmosphere of 200° C., tensile stress at 20% strain σ20 (N/mm2) of the polytetrafluoroethylene tube and tensile stress at 50% strain σ50 (N/mm2) of the polytetrafluoroethylene tube satisfy 2.0≤0.1×σ20+0.3×σ50

159. 发明授权

US11992635B2 Medical balloon assembly 有权
公开(公告)号：US11992635B2
公开(公告)日：2024-05-28
申请号：US16794766
申请日：2020-02-19
申请人： MEDTRONIC VASCULAR, INC.
发明人： Risa Tom Egerter
IPC分类号： A61M25/10 , A61L29/04 , A61L29/06 , A61M25/00 , B29C48/00
CPC分类号： A61M25/1029 , A61L29/049 , A61L29/06 , A61M25/0045 , A61M25/1006 , A61M25/1025 , A61M25/1034 , A61M25/1036 , B29C48/00 , A61M2025/1031 , A61M2025/1056 , A61M2025/1075 , A61M2025/1093
摘要： In one aspect, a medical balloon assembly includes a tip sleeve secured to the distal end portion of a balloon catheter that includes the distal neck of a balloon. The tip sleeve has at least an inner layer and an outer layer. The inner layer is formed from a bondable material that is directly bondable to the exterior of the distal neck portion of the balloon. The tip sleeve is bonded directly to the distal neck of the balloon. The outer layer is formed from a lubricious polymer. Such a medical balloon assembly is made by receiving the distal neck inside the proximal end portion of the tip sleeve and directly bonding the distal neck of the balloon to the inner layer of the tip sleeve.

160. 发明公开

US20240131221A1 IONIC COMPOUNDS FOR MEDICAL DEVICE APPLICATIONS 审中-公开
公开(公告)号：US20240131221A1
公开(公告)日：2024-04-25
申请号：US18367131
申请日：2023-09-12
申请人： Becton, Dickinson and Company
发明人： He Bai , James Joseph Semler
IPC分类号： A61L27/26 , A61L27/54 , A61L29/06 , A61L29/08 , A61L29/16
CPC分类号： A61L27/26 , A61L27/54 , A61L29/06 , A61L29/085 , A61L29/16 , A61L2300/206 , A61L2300/406 , A61L2300/42 , A61L2300/602 , A61L2300/606
摘要： Medical articles formed from ionically bonding an ionic compound and an active agent provide enhanced properties. The ionic compound comprises an ionic additive incorporated into a base polymer. The ionic additive may be one or more of an anionic additive, a cationic additive, and a zwitterionic additive. Medical articles herein have antimicrobial, anti-fouling, and/or antithrombotic characteristics.

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