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111. 发明申请

US20100243915A1 FLUORESCENCE DETECTION SYSTEM 有权
标题翻译：荧光检测系统
公开(公告)号：US20100243915A1
公开(公告)日：2010-09-30
申请号：US12438722
申请日：2008-02-20
申请人： Takashi Fukuzawa
发明人： Takashi Fukuzawa
IPC分类号： G01N21/64 , G01J1/58
CPC分类号： G01N21/645 , G01N2021/6484
摘要： A fluorescence detection system capable of detecting fluorescence with a high sensitivity even if a sample generating fluorescence is small in amount includes a light source emitting excitation light, a probe arranged in opposition to a sample unit, an optical multiplexer/demultiplexer, a detector, a first optical fiber connecting the light source to the optical multiplexer/demultiplexer, a second optical fiber connecting the probe to the optical multiplexer/demultiplexer, and a third optical fiber connecting the detector to the optical multiplexer/demultiplexer. An excitation filter, serving as a short-pass filter, is arranged on the first optical fiber and a detection filter serving as a long-pass filter is arranged on the third optical fiber. The optical multiplexer/demultiplexer includes a multiplexing/demultiplexing filter serving as a long-pass filter.
摘要翻译：即使产生荧光的样品量少的荧光检测系统也能够高灵敏度地检测荧光，包括发射激发光的光源，与样品单元相对布置的探针，光复用器/解复用器，检测器，将光源连接到光复用器/解复用器的第一光纤，将探针连接到光复用器/解复用器的第二光纤和将检测器连接到光复用器/解复用器的第三光纤。用作短路滤波器的激励滤波器布置在第一光纤上，并且在第三光纤上布置用作长通滤波器的检测滤波器。光复用器/解复用器包括用作长通滤波器的复用/解复用滤波器。

112. 发明授权

US07795600B2 Wavelength conversion chip for use with light emitting diodes and method for making same 有权
公开(公告)号：US07795600B2
公开(公告)日：2010-09-14
申请号：US11975406
申请日：2007-10-19
申请人： Karl W. Beeson , Scott M. Zimmerman , William R. Livesay
发明人： Karl W. Beeson , Scott M. Zimmerman , William R. Livesay
IPC分类号： G01J1/58
CPC分类号： H05B33/10 , H01L33/508 , H01L2924/0002 , H01L2933/0041 , H01L2924/00
摘要： A wavelength conversion chip is formed by depositing a wavelength conversion material on a substrate to form a layer, removing the resulting wavelength conversion layer from the substrate and then segmenting the wavelength conversion layer into a plurality of wavelength conversion chips. The wavelength conversion material can be annealed by thermal annealing or radiation annealing to increase the wavelength conversion efficiency of the chips or to sinter the wavelength conversion material to form a ceramic material. Optical coatings, vias, light extraction elements, electrical connections or electrical bond pads can be fabricated on the wavelength conversion chips.

113. 发明申请

US20100224796A1 Imaging System Using Dynamic Speckle Illumination 审中-公开
标题翻译：使用动态斑点照明的成像系统
公开(公告)号：US20100224796A1
公开(公告)日：2010-09-09
申请号：US11991772
申请日：2006-09-08
申请人： Jerome Mertz , Catherine Ventalon
发明人： Jerome Mertz , Catherine Ventalon
IPC分类号： G01N21/64 , G01J1/58
CPC分类号： G02B21/0076 , G02B21/0056 , G02B21/16
摘要： A versatile, imaging system that uses dynamic speckle illumination (DSI) is disclosed. The DSI microscope includes at least one light source for producing light to illuminate a target object in an object plane; an image recording device for recording a sequence of images of the target object; imaging optics for transmitting signal light from the target object as the sequence of images from the target object to the image recording device; and a dynamic speckle generating system for illuminating the target object with dynamic speckle.
摘要翻译：公开了一种使用动态斑点照明（DSI）的通用成像系统。 DSI显微镜包括至少一个用于产生光以照亮物体平面中的目标物体的光源; 用于记录目标对象的图像序列的图像记录装置; 用于将来自所述目标物体的信号光作为从所述目标物体到所述图像记录装置的图像序列的成像光学装置; 以及用动态斑点照射目标物体的动态斑点发生系统。

114. 发明授权

US07791046B2 High efficiency fiber-optic scintillator radiation detector 有权
标题翻译：高效光纤闪烁体辐射探测器
公开(公告)号：US07791046B2
公开(公告)日：2010-09-07
申请号：US12154061
申请日：2008-05-20
申请人： Juha-Pekka J. Laine , Peter Miraglia , H. Charles Tapalian, Jr.
发明人： Juha-Pekka J. Laine , Peter Miraglia , H. Charles Tapalian, Jr.
IPC分类号： G01J1/58
CPC分类号： G01T1/20
摘要： A fiber-optic scintillation radiation detector includes: a cladding; a core extending within the cladding; and a scintillator contiguous with the core within the cladding responsive to particle and/or photon radiation by providing scintillation photons, which are then primarily propagated in the core.
摘要翻译：光纤闪烁放射线检测器包括：包层; 在包层内延伸的芯; 以及通过提供闪烁光子（其随后在核心中主要传播）的内部响应于颗粒和/或光子辐射而与包层内的芯连接的闪烁体。

115. 发明申请

US20100213389A1 METHOD, SYSTEM, AND COMPUTER PROGRAM PRODUCT FOR LOCALIZING PHOTONS AND A LIGHT SOURCE EMITTING THE PHOTONS 失效
标题翻译：用于定位光子的方法，系统和计算机程序产品以及发射光子的光源
公开(公告)号：US20100213389A1
公开(公告)日：2010-08-26
申请号：US12709908
申请日：2010-02-22
申请人： Josh Larkin , Nelson Publicover , John Sutko
发明人： Josh Larkin , Nelson Publicover , John Sutko
IPC分类号： G01N21/64 , G01J1/58
CPC分类号： G01N21/6458 , G01J1/58 , G01N15/1429 , G01N15/1434
摘要： Localization methods and methods for localizing a light source using multivariate statistical analysis. In particular, a multi-variate distribution, such as a multi-variate normal distribution, may be used to localize photons originating from a light source and, in particular, may be used to analyze photon position maps acquired by Photon Event Distribution Sampling (PEDS). The multi-variate distribution assigned to each of the photons in the photon position map may be summed to predict a most probable location for the light source.
摘要翻译：使用多变量统计分析来定位光源的本地化方法和方法。特别地，可以使用诸如多变量正态分布的多变量分布来定位源自光源的光子，并且特别地可以用于分析由光子事件分布采样（PEDS）获取的光子位置图）。分配给光子位置图中的每个光子的多变量分布可以相加以预测光源的最可能的位置。

116. 发明申请

US20100213387A1 PORTABLE CORROSION DETECTION APPARATUS 有权
标题翻译：便携式腐蚀检测装置
公开(公告)号：US20100213387A1
公开(公告)日：2010-08-26
申请号：US12390965
申请日：2009-02-23
申请人： Morteza Safai , Gary E. Georgeson
发明人： Morteza Safai , Gary E. Georgeson
IPC分类号： G01J1/58 , G01N21/00
CPC分类号： G01N21/88 , B82Y15/00 , G01N17/006 , G01N2201/0221
摘要： A method and apparatus comprising a housing, an excitation unit, and a detector. The housing is portable and capable of being positioned relative to a location on an object. Quantum dots are present in the location. The excitation unit is mounted to the housing. The excitation unit is capable of sending energy into the location in which the energy is capable of causing a response from the quantum dots. The detector is mounted to the housing. The detector is capable of detecting the response from the quantum dots in the location.
摘要翻译：一种包括壳体，激励单元和检测器的方法和装置。外壳是便携式的并且能够相对于物体上的位置定位。量子点存在于该位置。励磁单元安装在壳体上。激发单元能够将能量发送到能量能够引起来自量子点的响应的位置。检测器安装在外壳上。检测器能够检测位置上量子点的响应。

117. 发明申请

US20100207037A1 SYSTEM, METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR PROVIDING WIDE-FIELD SUPERRESOLUTION MICROSCOPY 失效
标题翻译：系统，方法和计算机可访问介质，用于提供广域超滤镜显微镜
公开(公告)号：US20100207037A1
公开(公告)日：2010-08-19
申请号：US12693563
申请日：2010-01-26
申请人： Guillermo J. Tearney , Brett E. Bouma , Jing Yuan
发明人： Guillermo J. Tearney , Brett E. Bouma , Jing Yuan
IPC分类号： G01N21/64 , G01J1/58
CPC分类号： G01N21/6458 , G02B21/0032 , G02B21/0072 , G02B21/0076 , G02B21/16 , G02B27/48
摘要： Exemplary embodiments of apparatus, system, method and computer-accessible medium using which at least one first pulsed electro-magnetic radiation is generated. Such radiation depletes at least one excited state of at least one molecule. Further, it is possible to generate at least one second electro-magnetic radiation based on the first pulsed electro-magnetic radiation(s). For example, the second electro-magnetic radiation(s) can have a pattern with a plurality of spots.
摘要翻译：产生至少一个第一脉冲电磁辐射的装置，系统，方法和计算机可访问介质的示例性实施例。这种辐射消耗至少一种分子的至少一种激发态。此外，可以基于第一脉冲电磁辐射产生至少一个第二电磁辐射。例如，第二电磁辐射可以具有具有多个点的图案。

118. 发明申请

US20100181496A1 IN-SITU PLANT ANALYSIS APPARATUS, METHOD FOR TRACKING THE STATE OR EVOLUTION OF A CULTURE AND METHOD FOR MANAGING VEGETABLE PROCESSING 有权
标题翻译：现场设备分析装置，跟踪文化状态或演变的方法和管理植物加工的方法
公开(公告)号：US20100181496A1
公开(公告)日：2010-07-22
申请号：US12602582
申请日：2008-05-29
申请人： Nicolae Moise , Gwendal Latouche , Zoran Cerovic , Yves Goulas , Jean-Luc Ayral
发明人： Nicolae Moise , Gwendal Latouche , Zoran Cerovic , Yves Goulas , Jean-Luc Ayral
IPC分类号： G01N21/64 , G01J1/58
CPC分类号： G01N21/645 , G01N2021/1736 , G01N2021/6419 , G01N2021/6421 , G01N2021/6493 , G01N2021/8466 , G01N2201/0221 , G01N2201/062 , G01N2201/0627 , G01N2201/0696
摘要： A device for analyzing plants, by luminous excitation and fluorescence measurement, can be used on site without preparation of the plants. The device evaluates the content of a compound in the skin or epidermis of a plant. The geometry of the device is characterized by a direction of the excitation light rays and a direction of the fluorescence light rays which are non-collinear with each other. The device includes several sets of emitters of different wavelengths, each including several emitters, and makes it possible to measure a plurality of excitation-fluorescence combinations. A method for evaluating and monitoring the development and maturity of a crop, as well as a method for monitoring and controlling plant treatment are also described.
摘要翻译：用于通过发光激发和荧光测量分析植物的装置可以在现场使用而不需要植物的准备。该装置评估化合物在植物的皮肤或表皮中的含量。器件的几何形状的特征在于激发光线的方向和彼此不共线的荧光光线的方向。该装置包括不同波长的几组发射器，每组包括几个发射器，并且可以测量多个激发荧光组合。还描述了评估和监测作物的发育和成熟的方法以及监测和控制植物处理的方法。

119. 发明申请

US20100148073A1 System and Method for Structured Illumination and Collection for Improved Optical Confocality of Raman Fiber Array Spectral Translator Imaging and Interactive Raman Probing 有权
标题翻译：用于拉曼光纤阵列光谱转换成像和交互式拉曼探测的改进光学谐振的结构照明和采集系统和方法
公开(公告)号：US20100148073A1
公开(公告)日：2010-06-17
申请号：US12632187
申请日：2009-12-07
申请人： Matthew P. Nelson , Patrick J. Treado
发明人： Matthew P. Nelson , Patrick J. Treado
IPC分类号： G01T1/28 , G01J1/58 , G01N21/65 , G01N21/64 , G01J3/44
CPC分类号： G01J3/2803 , G01J3/0221 , G01J3/44 , G01N21/474 , G01N21/55 , G01N21/645 , G01N21/6456 , G01N21/65 , G01N2021/6423 , G01N2021/6484 , G01N2201/0833 , G01N2201/0846 , G02B6/06
摘要： The disclosure relates generally to methods and apparatus for using telescope optics and a fiber array spectral translator-based (“FAST”) spectroscopic system for improved imaging, spectral analysis, and interactive probing of a sample. In an embodiment, the confocality of a fiber array spectral translator-based spectroscopic system is improved through the use of structured illumination and/or structured collection of photons. User input may be received and acted upon to allow a user to interactively in real time and/or near real time view and analyze specific regions of the sample.
摘要翻译：本公开一般涉及用于使用望远镜光学器件的方法和装置以及用于改进样品的成像，光谱分析和交互式探测的光纤阵列光谱转换器（“FAST”）光谱系统。在一个实施例中，通过使用结构化照明和/或光子的结构化收集来提高基于光纤阵列光谱转换器的光谱系统的共焦度。可以接收用户输入并执行操作以允许用户以实时和/或接近实时的方式进行交互式查看和分析样本的特定区域。

120. 发明申请

US20100140460A1 DEVICE FOR THE EXALTED DETECTION OF THE EMISSION OF A TARGET PARTICLE 有权
标题翻译：用于显着检测目标颗粒的排放的装置
公开(公告)号：US20100140460A1
公开(公告)日：2010-06-10
申请号：US12515664
申请日：2007-11-21
申请人： Hervé Rigneault , Pierre-Francois Lenne , Jerome Wenger , Evgueni Popov , Thomas Ebbesen
发明人： Hervé Rigneault , Pierre-Francois Lenne , Jerome Wenger , Evgueni Popov , Thomas Ebbesen
IPC分类号： G01J3/50 , G01J1/58
CPC分类号： G01N21/6428 , G01N21/6452
摘要： The invention relates to a device (1) for detecting the emission of a target particle (6) at an emission wavelength, said device comprising: a photo-detector (2, 2A, 2B) comprising a sensitive detection surface having a high optical index; wherein said target particle (6) can be positioned in the vicinity of said sensitive surface in an analysis medium (13) having a low optical index; said device being characterised in that it further comprises: a mask (3) covering said sensitive surface, said mask including at least one area (4) opaque at said emission wavelength and at least one hole (5), said hole being capable of receiving the target particle; and in that the mask includes at least one interface; 7 said device further comprising at least one groove (10, 10A, 10B) provided at said interface, each of said at least one groove surrounding each of said at least one hole.
摘要翻译：本发明涉及一种用于检测发射波长的目标颗粒（6）的发射的装置（1），所述装置包括：光检测器（2,2A，2B），包括具有高光学指数的敏感检测表面 ; 其中所述目标颗粒（6）可以位于具有低光学指数的分析介质（13）中的所述敏感表面附近; 所述装置的特征在于，其还包括：覆盖所述敏感表面的掩模（3），所述掩模包括至少一个在所述发射波长处不透明的区域（4）和至少一个孔（5），所述孔能够接收目标粒子; 并且所述掩模包括至少一个界面; 7，所述装置还包括设置在所述界面处的至少一个凹槽（10,10A，10B），每个所述至少一个凹槽围绕所述至少一个孔的每一个。

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