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111. 发明授权

US08702678B2 Assemblies, systems, and methods for infusing therapeutic agents into the body 有权
标题翻译：用于将治疗剂注入体内的装置，系统和方法
公开(公告)号：US08702678B2
公开(公告)日：2014-04-22
申请号：US13564608
申请日：2012-08-01
申请人： Anthony J. Comerota , Thomas J. Fogarty , Jonathan M. Olson , Richard A. Lotti
发明人： Anthony J. Comerota , Thomas J. Fogarty , Jonathan M. Olson , Richard A. Lotti
IPC分类号： A61M25/09 , A61M25/10 , A61M5/14
CPC分类号： A61M25/0074 , A61B5/4887 , A61M5/14 , A61M19/00 , A61M25/0023 , A61M25/0026 , A61M25/007 , A61M25/0108 , A61M25/09 , A61M2025/0004 , A61M2025/0018 , A61M2025/0057 , A61M2025/0079 , A61M2025/0175 , A61M2202/048
摘要： An infusion catheter assembly has the ability to infinitely titrate the length of a porous fluid distribution section in situ. The infusion catheter assembly thereby provides a length of infusion that can be infinitely varied over a prescribed range, to control the effective infusion length and the rate of infusion. Using the infusion catheter assembly, a physician has the capability to treat only the length of the vessel desired, thereby preventing excessive drug/patient exposures. The porous fluid distribution section can include an array of spaced apart apertures that vary in size and/or density along the length of the porous fluid distribution section, such that the flow rate remains essentially constant for a given inlet pressure independent of the effective infusion length.
摘要翻译：输液导管组件具有无限地滴定多孔流体分配部分的长度的能力。因此，输注导管组件提供可以在规定范围内无限变化的输注长度，以控制有效的输注长度和输注速率。使用输注导管组件，医师具有仅治疗期望血管长度的能力，从而防止药物/患者过度暴露。多孔流体分配部分可以包括沿着多孔流体分配部分的长度在尺寸和/或密度上变化的间隔开的孔的阵列，使得对于给定的入口压力而言，独立于有效输注长度的流速保持基本上恒定。

112. 发明授权

US08684963B2 Catheter with a dual lumen monolithic shaft 有权
标题翻译：导管与双腔单片轴
公开(公告)号：US08684963B2
公开(公告)日：2014-04-01
申请号：US13542129
申请日：2012-07-05
申请人： Hua Qiu , Tung-Liang Lin
发明人： Hua Qiu , Tung-Liang Lin
IPC分类号： A61M29/00
CPC分类号： A61M25/1025 , A61M25/0009 , A61M25/0026 , A61M25/0032 , A61M25/0045 , A61M25/10 , A61M2025/0183 , A61M2025/1061
摘要： Multi-lumen catheter having a monolithic elongate tubular shaft member having a proximal end, a distal end and a longitudinal length therebetween. The tubular shaft member has an outer cross-sectional dimension that varies along the length of the tubular shaft member. The tubular shaft member has an inner core made of a first material and an outer layer made of a second material. The inner core has a first lumen and a second lumen defined therein, the first lumen having a first lumen cross-section and a length extending at least along a portion of the length of the tubular shaft member. The first lumen cross-section is substantially uniform along the length of the first lumen. The second lumen has a second lumen cross-section and a length extending along the length of tubular shaft member. The second lumen cross-section is substantially uniform along the length of the second lumen.
摘要翻译：具有整体式细长管状轴构件的多腔导管具有近端，远端和其间的纵向长度。管状轴构件具有沿管状轴构件的长度变化的外侧横截面尺寸。管状轴构件具有由第一材料制成的内芯和由第二材料制成的外层。内芯具有限定在其中的第一内腔和第二腔，第一腔具有第一内腔横截面和至少沿着管状轴构件的长度的一部分延伸的长度。第一管腔横截面沿着第一管腔的长度基本均匀。第二腔具有第二管腔横截面和沿着管状轴构件的长度延伸的长度。第二管腔横截面沿第二内腔的长度基本均匀。

113. 发明申请

US20140066830A1 CEREBROSPINAL FLUID PURIFICATION SYSTEM 有权
标题翻译： CEREBROSPINAL流体净化系统
公开(公告)号：US20140066830A1
公开(公告)日：2014-03-06
申请号：US13801215
申请日：2013-03-13
申请人： Shivanand Lad , William C. Mobley , Karoly Nikolich , Thomas Saul
发明人： Shivanand Lad , William C. Mobley , Karoly Nikolich , Thomas Saul
IPC分类号： A61M27/00
CPC分类号： A61M27/006 , A61M1/3679 , A61M25/0026 , A61M2025/0007 , A61M2027/004 , A61M2202/0021 , A61M2202/0464 , A61M2202/203 , A61M2202/206 , A61M2206/16 , A61M2210/0693 , A61M2210/1003
摘要： The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a multilumen flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents.
摘要翻译：本发明提供了通过从CSF中除去目标化合物来调节脑脊髓液（CSF）的方法和系统。该系统提供多空间流动路径并在CSF空间中交换CSF的大部分体积部分。特定化合物的去除和/或递送可以针对特定疾病的病理学来定制。移除是针对性的，特异性的，例如通过使用特定的大小排除阈值，针对特定毒素的抗体和其他色谱技术，以及递送和/或去除靶向治疗剂。

114. 发明申请

US20140031742A1 CATHETER FOR TREATING ECTOPIC PREGNANCY, CATHETER GUIDE, AND CATHETER UNIT FOR TREATING ECTOPIC PREGNANCY, INCLUDING THE CATHETER AND THE CATHETER GUIDE 有权
标题翻译：用于治疗经济性怀孕的导管，导管导管和用于治疗心律失常的导管单元，包括电导管和导管指南
公开(公告)号：US20140031742A1
公开(公告)日：2014-01-30
申请号：US13982928
申请日：2011-11-25
申请人： Sun Haeng Kim , Yong Tae Kim , Kig Hoon Ahn
发明人： Sun Haeng Kim , Yong Tae Kim , Kig Hoon Ahn
IPC分类号： A61M25/00
CPC分类号： A61M25/0026 , A61B17/3478 , A61B17/42 , A61B17/435 , A61B2017/00318 , A61B2017/00323 , A61B2017/00867 , A61M25/0032 , A61M25/007 , A61M25/01 , A61M31/00 , A61M2025/0031 , A61M2025/0037
摘要： The present invention relates to a catheter for treating ectopic pregnancy, of which one end is inserted into the fallopian tube through the vaginal cavity, and the other end is exposed to the outside of the body, wherein the catheter comprises: at least one passage portion forming a liquid passage entering through the one end or the other end; a penetrative portion connected to the one end, and including a foremost end for penetrating the gestational sac; and a connecting portion connected to the other end, and capable of being coupled to at least one syringe tool for injecting or suctioning the liquid. Accordingly, side effects from open surgery can be prevented, and excellent treatment effects can be obtained by more safely and quickly treating ectopic pregnancy.
摘要翻译：本发明涉及一种用于治疗异位妊娠的导管，其中一端通过阴道腔插入输卵管，另一端暴露在体外，其中导管包括：至少一个通道部分形成通过一端或另一端进入的液体通道; 连接到所述一端的穿透部分，并且包括用于穿透所述妊娠囊的最前端; 以及连接部分，其连接到另一端，并且能够联接到至少一个注射器工具以用于注入或抽吸液体。因此，可以防止开放手术的副作用，通过更安全，快速地治疗异位妊娠，可以获得优异的治疗效果。

115. 发明授权

US08591497B2 Stretch valve balloon catheter and methods for producing and using same 有权
标题翻译：弹力气囊导管及其制造和使用方法
公开(公告)号：US08591497B2
公开(公告)日：2013-11-26
申请号：US13707752
申请日：2012-12-07
申请人： Mayser, LLC
发明人： Leonard Pinchuk , Gary A. Kalser , Gregory L. Mayback , James Leone
IPC分类号： A61M31/00 , A61M37/00 , A61M27/00
CPC分类号： A61M25/0017 , A61M25/0026 , A61M25/10185 , A61M25/10186 , A61M25/1027 , A61M2025/1093 , A61M2210/1085
摘要： A safety catheter includes a flexible, multi-lumen shaft having an outer diameter, a distal tip, a proximal catheter end with a drain end and a proximal inflation end. The multi-lumen shaft defines a drain lumen, a distal hollow balloon portion, at least one inflation lumen, and a drainage port. A hollow stretch valve is coaxially disposed in the inflation or drainage lumen, or both, has a fixed portion within the inflation or drainage lumen, or both, and prevents fluid from passing through the drainage port in a steady state and has a sliding portion slidably disposed within the inflation or drainage lumen, or both, such that, in a stretched state when the proximal catheter end is stretched, the sliding portion slides within the inflation or drainage lumen, or both to permit fluid to pass through the balloon drainage port and/or wall of the catheter.
摘要翻译：安全导管包括具有外径，远侧末端，具有排水端和近侧充气端的近侧导管端的柔性多腔轴。多腔轴限定排水腔，远端中空球囊部分，至少一个充气腔和排水口。中空拉伸阀同轴地设置在充气或排水腔或两者中，在充气或排水腔或两者内具有固定部分，并且防止流体在稳定状态下通过排水口，并且滑动部分可滑动地设置在充气或排液腔内或两者之间，使得当拉伸近端导管端时处于拉伸状态，滑动部分在充气或排液腔内或两者内滑动以允许流体通过气囊排出口和 /或导管壁。

116. 发明授权

US08579882B1 Cannula system 有权
标题翻译：插管系统
公开(公告)号：US08579882B1
公开(公告)日：2013-11-12
申请号：US13914664
申请日：2013-06-11
申请人： Covidien LP
发明人： Ferass Abuzaina , Ahmad Robert Hadba
IPC分类号： A61M25/00
CPC分类号： A61M25/0026 , A61B17/00491 , A61B2017/00495 , A61M2025/0039
摘要： The present disclosure provides a cannula useful for introducing a thermally responsive polymer in situ. In embodiments, the cannula possesses more than one cannula, with the thermally responsive polymer introduced in one cannula, and a material such as a coolant in a second cannula which prevents premature gelling of the thermally responsive polymer.
摘要翻译：本公开提供了可用于在原位引入热响应性聚合物的插管。在实施例中，插管具有多于一个插管，其中热响应聚合物引入一个插管中，以及诸如第二套管中的冷却剂的材料，其防止热响应聚合物过早凝胶化。

117. 发明申请

US20130296781A1 DEFLECTABLE CATHETER SHAFT SECTION, CATHETER INCORPORATING SAME, AND METHOD OF MANUFACTURING SAME 有权
标题翻译：不可预知的导管片部分，与其同时进入的导体及其制造方法
公开(公告)号：US20130296781A1
公开(公告)日：2013-11-07
申请号：US13838124
申请日：2013-03-15
申请人： ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC.
发明人： Troy T. Tegg , Salome A. Gonzalez
IPC分类号： A61M25/01
CPC分类号： A61M25/0147 , A61B5/01 , A61B5/042 , A61B5/6852 , A61B18/14 , A61B18/1492 , A61B2018/00821 , A61B2018/00839 , A61B2217/007 , A61M25/0009 , A61M25/0026 , A61M25/0136 , A61M25/0144 , A61M2025/0059 , A61M2025/015 , Y10T29/49863
摘要： A deflectable catheter shaft section is disclosed comprising an elongated body extending along a longitudinal axis and comprising a distal end and a proximal end; and a plurality of lumens extending along the longitudinal axis of the elongated body, wherein at least one of the lumens is abutting at least another one of the lumens. A catheter comprising the deflectable catheter shaft section and a method of manufacturing the deflectable catheter shaft section are also disclosed. A catheter incorporating a deflectable catheter shaft section can further comprise first and second compression coils disposed over pull wires located within the catheter, wherein the compression coils are unattached to the catheter or components thereof, but can be constrained by a shaft coupler at a distal end of each of the compression coils and by at least a portion of a handle assembly at a proximal end of each of the compression coils.
摘要翻译：公开了一种可偏转的导管轴部分，其包括沿着纵向轴线延伸并且包括远端和近端的细长主体; 以及沿着细长主体的纵向轴线延伸的多个腔，其中至少一个管腔邻接至少另一个管腔。还公开了一种包括可偏转导管轴部分的导管和制造可偏转导管轴部分的方法。包括可偏转导管轴部分的导管还可以包括布置在位于导管内的拉线上的第一和第二压缩线圈，其中压缩线圈未附接到导管或其部件，但是可以由远端的轴联接器约束每个压缩线圈的近端处的至少一部分手柄组件。

118. 发明申请

US20130289528A1 THERAPEUTIC DELIVERY DEVICES, SYSTEMS, AND METHODS 有权
公开(公告)号：US20130289528A1
公开(公告)日：2013-10-31
申请号：US13859395
申请日：2013-04-09
申请人： Grifols, S.A.
发明人： Dean Chamberlain , Valery Novokhatny , David Fineberg
IPC分类号： A61M25/10
CPC分类号： A61M25/10 , A61B17/1204 , A61B17/12109 , A61B17/12136 , A61B17/12172 , A61M25/00 , A61M25/0026 , A61M25/0043 , A61M25/0082 , A61M25/104 , A61M2025/0004 , A61M2025/0018 , A61M2025/0057 , A61M2025/0096 , A61M2025/105 , A61M2025/1052 , A61M2025/1081 , A61M2025/1097
摘要： Devices, systems, and methods for delivery of therapeutics, in particular thrombolytic agents, in particular plasmin, are provided. The devices, systems, and methods also provide for occlusion of a vessel or graft distal and/or proximal to a treatment zone. Also provided are devices, systems, and methods that trap emboli.

119. 发明申请

US20130281926A1 CANNULA FOR CARRYING OUT A REGIONAL EXTRACORPOREAL CIRCULATION 审中-公开
标题翻译：用于执行区域性超声波循环的肛门
公开(公告)号：US20130281926A1
公开(公告)日：2013-10-24
申请号：US13806492
申请日：2011-06-22
申请人： Maxime Raux , Armelle Nicolas-Robin
发明人： Maxime Raux , Armelle Nicolas-Robin
IPC分类号： A61M1/36 , A61B17/12 , A61M25/00
CPC分类号： A61M1/3653 , A61B17/12109 , A61B17/12136 , A61M1/3613 , A61M1/3659 , A61M25/0026 , A61M25/007 , A61M25/1002 , A61M2025/1052 , A61M2025/1097
摘要： The invention relates to a cannula for medical use, which is obstructed at the distal end thereof and which has an occlusion balloon enabling regionalization of the extracorporeal circulation, it being possible for said cannula to be multiperforated.
摘要翻译：本发明涉及一种用于医疗用途的套管，其在其远端处被阻塞并且具有能够使体外循环区分化的闭塞球囊，所述插管可以多孔穿孔。

120. 发明申请

US20130261605A1 Multi-Lumen Catheter with Enhanced Flow Features 有权
标题翻译：具有增强流量特征的多流明导管
公开(公告)号：US20130261605A1
公开(公告)日：2013-10-03
申请号：US13902488
申请日：2013-05-24
申请人： C. R. Bard, Inc.
发明人： Colin S. Gregersen , Ryan C. Patterson , Daniel H. Brittingham
IPC分类号： A61M25/00
CPC分类号： A61M25/0026 , A61M25/0009 , A61M25/0012 , A61M25/0021 , A61M25/0023 , A61M25/0032 , A61M25/0043 , A61M2025/0025 , A61M2025/0034 , A61M2025/0035 , A61M2025/0037
摘要： A multi-lumen catheter including an elliptical cross-sectional profile configuration that enhances fluid flow rate while minimizing the average diameter of the catheter body is disclosed. In one embodiment the catheter includes an elongate catheter tube defining a plurality of lumens. At least a portion of the longitudinal length of the catheter tube may define an elliptical cross section, in turn defined by a major axis and a minor axis. In one embodiment, a ratio of the major axis to the minor axis of the elliptical cross section is between about 1.3 and about 1.4. The catheter body can define two, three, or more lumens. In one embodiment, a dual-lumen catheter tube includes an aspect ratio of about 1.1:1, and each lumen thereof includes an inner surface defined by a plurality of radii and an hourglass-shaped septum.
摘要翻译：公开了一种包括椭圆形截面轮廓构造的多腔导管，其增加流体流速同时使导管体的平均直径最小化。在一个实施例中，导管包括限定多个内腔的细长导管。导管的纵向长度的至少一部分可以限定椭圆形横截面，又由长轴和短轴限定。在一个实施例中，椭圆截面的长轴与短轴的比率在约1.3和约1.4之间。导管主体可以限定两个，三个或更多流明。在一个实施例中，双腔导管包括约1.1:1的纵横比，并且其每个内腔包括由多个半径和沙漏形隔膜限定的内表面。

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