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1. 发明授权

US10278802B2 Self-adherent implants and methods of preparation 有权
公开(公告)号：US10278802B2
公开(公告)日：2019-05-07
申请号：US14970701
申请日：2015-12-16
申请人： Covidien LP
发明人： Brian Nentwick , Ahmad Robert Hadba
IPC分类号： A61F2/00 , B65D81/24 , A61B17/04 , A61B17/08 , A61F2/30
摘要： Implants are described herein which contain an activated adhesive on at least a portion of the surface of the implant. A release sheet may be positioned over at least a portion of the adhesive. Packages which contain the implants and methods of preparing the implants are also described.

2. 发明申请

US20170073486A1 Medical Devices Having Activated Surfaces 审中-公开
标题翻译：激活表面的医疗器械
公开(公告)号：US20170073486A1
公开(公告)日：2017-03-16
申请号：US15342488
申请日：2016-11-03
申请人： Covidien LP
发明人： Nadya Belcheva , Ferass Abuzaina , Amin Elachchabi , Mbiya Kapiamba , Ahmad Robert Hadba
IPC分类号： C08J7/12 , A61L31/04 , A61L31/16 , A61L31/06
CPC分类号： C08J7/12 , A61L31/04 , A61L31/042 , A61L31/043 , A61L31/044 , A61L31/048 , A61L31/06 , A61L31/14 , A61L31/148 , A61L31/16 , A61L33/06 , A61L2400/18 , C08J7/14 , C08J2300/16 , Y10T442/20
摘要： Implantable biocompatible polymeric medical devices include a substrate with an acid or base-modified surface which is subsequently modified to include click reactive members.
摘要翻译：植入式生物相容性聚合物医疗装置包括具有酸或碱改性表面的基底，其随后被修改以包括点击反应性构件。

3. 发明授权

US09017379B2 Knotted suture end effector 有权
标题翻译：打结缝合末端执行器
公开(公告)号：US09017379B2
公开(公告)日：2015-04-28
申请号：US13677625
申请日：2012-11-15
申请人： Covidien LP
发明人： Nicholas Maiorino , Ahmad Robert Hadba , Gerald Hodgkinson
IPC分类号： A61B17/04 , A61B17/06 , A61B17/00 , A61B17/064
CPC分类号： A61B17/06166 , A61B17/0401 , A61B2017/00526 , A61B2017/00867 , A61B2017/00871 , A61B2017/00893 , A61B2017/0403 , A61B2017/0417 , A61B2017/0427 , A61B2017/0464 , A61B2017/0477 , A61B2017/06176 , A61B2017/0647
摘要： A suture including a knotted end effector is provided. The suture includes a body portion defining a longitudinal axis and an end effector formed from the body portion. The end effector includes first and second extensions which extend outwardly from the longitudinal axis in opposite directions when the end effector is in a permanent configuration. The extensions of the end effector extend substantially along the longitudinal axis when the end effector is in a temporary position. In embodiments, at least a portion of the end effector includes a shape memory material.
摘要翻译：提供包括打结末端执行器的缝合线。缝合线包括限定纵向轴线的主体部分和由主体部分形成的端部执行器。末端执行器包括第一和第二延伸部，当末端执行器处于永久构型时，第一和第二延伸部在相反方向上从纵向轴线向外延伸。当末端执行器处于临时位置时，末端执行器的延伸部基本上沿着纵向轴线延伸。在实施例中，端部执行器的至少一部分包括形状记忆材料。

4. 发明申请

US20140236199A1 REVERSIBLE STIFFENING OF LIGHT WEIGHT MESH 有权
标题翻译：轻量重锤的可逆加强
公开(公告)号：US20140236199A1
公开(公告)日：2014-08-21
申请号：US14345810
申请日：2012-10-01
申请人： Sofradim Production , Covidien LP
发明人： Ahmad Robert Hadba , Olivier Lefranc , Jennifer Buffinton
IPC分类号： A61L31/14 , A61F2/00 , A61L31/10
CPC分类号： A61F2/0063 , A61L31/10 , A61L31/148 , A61L2420/06 , C08L67/04 , C08L71/02
摘要： An implant and a process for preparing such an implant are disclosed. The implant includes a mesh including a biodegradable polymeric coating having glass transition temperature of about 26° C. to about 36° C. The polymeric coating includes a first polymeric component including a lactone and a second polymeric component including a polyether. The first polymeric component is present in an amount from about 90% to about 99% of the polymeric coating and the second polymeric component is present in an amount from about 1% to about 10% of the polymeric coating.
摘要翻译：公开了一种植入物和用于制备这种植入物的方法。植入物包括具有约26℃至约36℃的玻璃化转变温度的可生物降解的聚合物涂层的网。聚合物涂层包括包含内酯的第一聚合物组分和包含聚醚的第二聚合物组分。第一聚合物组分以聚合物涂层的约90％至约99％的量存在，而第二聚合物组分以聚合物涂层的约1％至约10％的量存在。

5. 发明授权

US08679157B2 Bioactive substance in a barbed suture 有权
标题翻译：生物活性物质在有刺的缝合线
公开(公告)号：US08679157B2
公开(公告)日：2014-03-25
申请号：US13690614
申请日：2012-11-30
申请人： Covidien LP
发明人： Joshua B. Stopek , Matthew D. Cohen , Ahmad Robert Hadba , Gerald Hodgkinson
IPC分类号： A61B17/04
CPC分类号： A61L17/005 , A61B17/06166 , A61B2017/00336 , A61B2017/00867 , A61B2017/00871 , A61B2017/00889 , A61B2017/00893 , A61B2017/06057 , A61B2017/06176 , A61L17/06 , A61L2300/404 , A61L2300/41 , A61L2300/412 , A61L2300/416 , A61L2300/602 , A61L2400/16
摘要： Barbed surgical sutures are provided which include an elongated body and a plurality of barbs extending therefrom. A bioactive agent is disposed within barb angles formed between the barbs and the elongated body. The barbs may be made from a shape memory polymer having a permanent shape which may be deformed to a temporary shape, such that barbs of the suture extend at different barb angles in the different shape configurations. The barb angles of the permanent shape may be greater than the barb angles of the temporary shape, thereby exposing and/or releasing a bioactive agent after placement in tissue.
摘要翻译：提供了带刺的外科缝合线，其包括细长主体和从其延伸的多个倒钩。生物活性剂设置在倒钩和细长体之间形成的倒钩角内。倒钩可以由具有永久形状的形状记忆聚合物制成，其可以变形为临时形状，使得缝线的倒钩在不同形状构造中以不同的倒钩角度延伸。永久形状的倒刺角可以大于临时形状的倒钩角，从而在放置在组织中之后暴露和/或释放生物活性剂。

6. 发明申请

US20130281976A1 CANNULA SYSTEM 有权
公开(公告)号：US20130281976A1
公开(公告)日：2013-10-24
申请号：US13914664
申请日：2013-06-11
申请人： Covidien LP
发明人： Ferass Abuzaina , Ahmad Robert Hadba
IPC分类号： A61M25/00
CPC分类号： A61M25/0026 , A61B17/00491 , A61B2017/00495 , A61M2025/0039
摘要： The present disclosure provides a cannula useful for introducing a thermally responsive polymer in situ. In embodiments, the cannula possesses more than one cannula, with the thermally responsive polymer introduced in one cannula, and a material such as a coolant in a second cannula which prevents premature gelling of the thermally responsive polymer.

7. 发明授权

US09554782B2 Medical devices incorporating functional adhesives 有权
标题翻译：配有功能性粘合剂的医疗器械
公开(公告)号：US09554782B2
公开(公告)日：2017-01-31
申请号：US14309930
申请日：2014-06-20
申请人： Covidien LP , Sofradim Production
发明人： Ahmad Robert Hadba , Jack Kennedy , Sèbastien Ladet
IPC分类号： A61B17/08 , A61B17/00 , A61B17/34 , A61L29/14 , A61B17/02 , A61F2/00
CPC分类号： A61B17/00491 , A61B17/0218 , A61B17/3421 , A61B17/3423 , A61B2017/00495 , A61B2017/00884 , A61B2017/3419 , A61F2/0063 , A61F2002/0072 , A61L29/14
摘要： A method for treating a wound or defect at a surgical target site using a minimally invasive surgical procedure is provided which includes utilizing a surgical access device such as a port or a catheter having a plurality of reactive members of a specific binding pair releasably contained on a surface of the access device, the reactive members having affinity for binding a cellular component of tissue cells located at the target site; contacting the surface of the access device with the tissue cells, wherein upon contact of the reactive members on the surface of the access device with the tissue cells, the reactive members are released from the surface of the access device and bind to the tissue; providing a tissue repair member having secured thereto a plurality of complementary reactive members of the specific binding pair; and applying the tissue repair member to the tissue, wherein upon contact of the complementary reactive members on the surface of the tissue repair member with the reactive members on the tissue, covalent bonds are formed between the reactive members and the complementary reactive members, thus bonding the tissue repair member to the tissue. A surgical access device for use in minimally invasive surgery is provided which includes a plurality of reactive members of a specific binding pair releasably contained on a surface of the access device, the reactive members having an affinity for binding a cellular component of tissue cells and another affinity for binding complementary members of the specific binding pair.
摘要翻译：提供了一种使用微创外科手术来治疗外科手术对象部位的伤口或缺损的方法，其包括利用外科进入装置，例如端口或导管，其具有可释放地包含在所述反应性成员对位于所述靶位点处的组织细胞的细胞组分的结合具有亲和力; 使进入装置的表面与组织细胞接触，其中当接触装置的表面上的反应性构件与组织细胞接触时，反应构件从进入装置的表面释放并结合到组织; 提供组织修复构件，其固定有多个所述特异性结合对的互补反应性成员; 以及将组织修复构件施加到组织，其中当组织修复构件的表面上的互补反应性构件与组织上的反应性构件接触时，在反应构件和互补反应构件之间形成共价键，从而结合组织修复构件到组织。提供了一种用于微创手术的手术进入装置，其包括可释放地包含在进入装置的表面上的特异性结合对的多个反应性成员，所述反应性成员具有结合组织细胞的细胞组分和另一种的亲和力对特异性结合对的互补成员的结合的亲合力。

8. 发明授权

US09526603B2 Reversible stiffening of light weight mesh 有权
标题翻译：轻质网状物的可逆硬化
公开(公告)号：US09526603B2
公开(公告)日：2016-12-27
申请号：US14345810
申请日：2012-10-01
申请人： Covidien LP , Sofradim Production
发明人： Ahmad Robert Hadba , Olivier Lefranc , Jennifer Buffinton
IPC分类号： A61F2/00 , A61L31/14 , A61L31/10 , C08L67/04 , C08L71/02
CPC分类号： A61F2/0063 , A61L31/10 , A61L31/148 , A61L2420/06 , C08L67/04 , C08L71/02
摘要： An implant and a process for preparing such an implant are disclosed. The implant includes a mesh including a biodegradable polymeric coating having glass transition temperature of about 26° C. to about 36° C. The polymeric coating includes a first polymeric component including a lactone and a second polymeric component including a polyether. The first polymeric component is present in an amount from about 90% to about 99% of the polymeric coating and the second polymeric component is present in an amount from about 1% to about 10% of the polymeric coating.
摘要翻译：公开了一种植入物和用于制备这种植入物的方法。植入物包括具有约26℃至约36℃的玻璃化转变温度的可生物降解的聚合物涂层的网。聚合物涂层包括包含内酯的第一聚合物组分和包含聚醚的第二聚合物组分。第一聚合物组分以聚合物涂层的约90％至约99％的量存在，而第二聚合物组分以聚合物涂层的约1％至约10％的量存在。

9. 发明申请

US20160100927A1 Self-Adherent Implants and Methods of Preparation 审中-公开
标题翻译：自粘植入物及其制备方法
公开(公告)号：US20160100927A1
公开(公告)日：2016-04-14
申请号：US14970701
申请日：2015-12-16
申请人： Covidien LP
发明人： Brian Nentwick , Ahmad Robert Hadba
IPC分类号： A61F2/00 , B65D81/24
CPC分类号： A61F2/0095 , A61B17/0401 , A61B17/085 , A61F2/0063 , A61F2/0077 , A61F2002/0072 , A61F2002/30448 , A61F2220/005 , B65D81/245
摘要： Implants are described herein which contain an activated adhesive on at least a portion of the surface of the implant. A release sheet may be positioned over at least a portion of the adhesive. Packages which contain the implants and methods of preparing the implants are also described.
摘要翻译：本文描述了植入物，其在植入物表面的至少一部分上含有活化的粘合剂。剥离片可以位于粘合剂的至少一部分上方。还描述了包含植入物和制备植入物的方法的包装。

10. 发明申请

US20150157769A1 MEDICAL DEVICES HAVING ACTIVATED SURFACES 有权
标题翻译：具有活化表面的医疗装置
公开(公告)号：US20150157769A1
公开(公告)日：2015-06-11
申请号：US14621493
申请日：2015-02-13
申请人： Covidien LP
发明人： Nadya Belcheva , Ferass Abuzaina , Amin Elachchabi , Mbiya Kapiamba , Ahmad Robert Hadba
IPC分类号： A61L31/06 , A61L31/14 , A61L31/04
CPC分类号： C08J7/12 , A61L31/04 , A61L31/042 , A61L31/043 , A61L31/044 , A61L31/048 , A61L31/06 , A61L31/14 , A61L31/148 , A61L31/16 , A61L33/06 , A61L2400/18 , C08J7/14 , C08J2300/16 , Y10T442/20
摘要： Implantable biocompatible polymeric medical devices include a substrate with an acid or base-modified surface which is subsequently modified to include click reactive members.
摘要翻译：植入式生物相容性聚合物医疗装置包括具有酸或碱改性表面的基底，其随后被修改以包括点击反应性构件。

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