专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

111. 发明授权

US5480334A Nested automatically separable flying disk assembly 失效
标题翻译：嵌套自动可分离飞盘组件
公开(公告)号：US5480334A
公开(公告)日：1996-01-02
申请号：US231165
申请日：1994-04-22
申请人： James M. Wilson , Dean M. Wilson
发明人： James M. Wilson , Dean M. Wilson
IPC分类号： A63H33/18 , A63H27/00
CPC分类号： A63H33/18
摘要： The nested automatically separable flying disk assembly includes an outer or cover disk assembly enclosing a nested or inner disk assembly. The outer or cover disk assembly is of a generally cylinderical disk shape having an air space between itself and the nested or inner disk assembly provided by a central nub projection cooperating with flange nub projections. The nested or inner disk assembly is provided with an outer peripheral flange section extended downwardly and below a similar peripheral rim section on the outer or cover disk assembly for allowing air to flow therebetween to cause the desired separation between the nested disk assemblies. An adjustable central nub projection is provided to adjustably change separation between the outer or cover disk assembly and the nested or inner disk assembly. The nested or inner disk assembly is provided with a plurality of inclined concentric aerodynamic ridges to alter air flow and resultant turbulence of air flow between the nested disk assemblies to vary the aerodynamic flight characteristics thereof. Second and third embodiments provide different angular relationships, either inwardly or outwardly, of the outer adjacent peripheral rim section of the outer or cover disk assembly and the peripheral flange section of the nested or inner disk assembly to achieve an increase or decrease in the time of separation of the outer or cover disk assembly from the nested or inner disk assembly.
摘要翻译：嵌套的可自动分离的飞盘组件包括封闭嵌套或内部盘组件的外部或盖板组件。外盘或盖盘组件具有大致圆柱形盘形，在其与由与凸缘凸起突起配合的中心凸起突起提供的嵌套或内盘组件之间具有空气空间。嵌套或内盘组件设置有外周凸缘部分，该外周边凸缘部分在外盘盖组件或盖盘组件上向下延伸并位于类似的周边边缘部分下面，以允许空气在其间流动，从而在嵌套盘组件之间产生期望的间隔。提供可调节的中央凸起凸起以可调节地改变外部或盖盘组件与嵌套或内部盘组件之间的间隔。嵌套或内盘组件设置有多个倾斜的同心空气动力学脊，以改变空中流动，并导致嵌套圆盘组件之间的空气流动的湍流，以改变其空气动力学飞行特性。第二和第三实施例提供外部或覆盖盘组件的外部相邻外围边缘部分的内向或向外的不同的角度关系，以及嵌套或内部盘组件的周边凸缘部分以实现时间的增加或减少外部或盖盘组件与嵌套或内部盘组件的分离。

112. 发明授权

US5460959A Transduced fibroblasts 失效
标题翻译：转导成纤维细胞
公开(公告)号：US5460959A
公开(公告)日：1995-10-24
申请号：US70646
申请日：1993-06-01
申请人： Richard C. Mulligan , James M. Wilson
发明人： Richard C. Mulligan , James M. Wilson
IPC分类号： C12N15/09 , A61K38/00 , A61K48/00 , C07K14/635 , C12N15/65 , C12N15/867 , C12N5/10 , C12N15/86
CPC分类号： C07K14/635 , A61K48/00 , C12N15/65 , C12N15/86 , A61K38/00 , C12N2740/13043 , C12N2740/16043
摘要： Fibroblasts transduced with genetic material encoding a polypeptide or protein of interest and, optionally, a selectable marker, as well as methods for making and using the transduced fibroblasts. Such fibroblasts are useful in delivering the encoded polypeptide or protein, such as an enzyme, a hormone or a drug, to an individual who has had a graft or implant of the transduced cells.
摘要翻译：用编码目的多肽或蛋白质的遗传物质和任选的选择性标记物转导的成纤维细胞以及制备和使用转导的成纤维细胞的方法。这样的成纤维细胞可用于将经编码的多肽或蛋白质，例如酶，激素或药物递送至具有转导细胞的移植物或植入物的个体。

113. 发明授权

US5135824A Coaxial terminal construction for a sealed pressurized battery 失效
标题翻译：密封式加压电池同轴端子结构
公开(公告)号：US5135824A
公开(公告)日：1992-08-04
申请号：US590005
申请日：1990-09-28
申请人： Kenneth R. Jones , James M. Wilson
发明人： Kenneth R. Jones , James M. Wilson
IPC分类号： H01M2/06 , H01M2/30 , H01M10/34
CPC分类号： H01M2/06 , H01M10/345 , H01M2/30
摘要： A coaxial terminal construction for a sealed pressurized battery. The battery includes a sealed vessel containing a series of battery cells and positive and negative poles are connected to the cells. A pre-assembled terminal unit extends through an annular mounting flange that is secured within an opening in the vessel wall and the pre-assembled unit includes an inner electode, an outer electrode, which is disposed concentrically outward of the inner electrode and insulated therefrom, and an annular mounting member which is located concentrically outward of the outer electrode and insulated therefrom. All three concentric members have external threads of the same pitch. The terminal unit is installed by threading the mounting member in the mounting flange of the vessel and simultaneously threading the outer electrode with a nut connected to one of the poles and threading the inner electrode with a second nut connected to the other of the poles. The mounting member can be crimped inwardly to provide a seal between the three concentric members.
摘要翻译：用于密封加压电池的同轴端子结构。电池包括含有一系列电池单元的密封容器，正极和负极连接到电池。预组装的端子单元延伸穿过固定在容器壁中的开口内的环形安装凸缘，并且预组装单元包括内电极，外电极，其同心地设置在内电极的外部并与其绝缘，以及环形安装构件，其同心地位于外部电极的外部并与其绝缘。所有三个同心构件具有相同间距的外螺纹。端子单元通过将安装构件穿过容器的安装凸缘而安装，同时用连接到一个极的螺母穿过外部电极，并用连接到另一个极的第二螺母穿过内部电极。安装构件可以向内压接以在三个同心构件之间提供密封。

114. 发明授权

US4670243A Method of precipitating metal titanate powders 失效
标题翻译：沉淀金属钛酸盐粉末的方法
公开(公告)号：US4670243A
公开(公告)日：1987-06-02
申请号：US880193
申请日：1986-06-30
申请人： James M. Wilson , Dana L. Coller , Subramaniam Venkataramani
发明人： James M. Wilson , Dana L. Coller , Subramaniam Venkataramani
IPC分类号： C01G23/00
CPC分类号： C01G23/006 , C01P2002/72 , C01P2002/76 , C01P2002/88 , C01P2004/03 , C01P2004/62 , C01P2006/12 , C01P2006/36
摘要： A titanium acylate solution is produced by adding glacial acetic acid to tetra-isopropyl titanate. Distilled water is then added until the solution clears, and a high grade alkaline-earth metal carbonate, such as BaCO.sub.3, SrCO.sub.3 or CaCO.sub.3, or a combination thereof, is added and agitated until the earth-metal dissolves and the solution again becomes clear. An alkaline hydroxide, such as NaOH, is added until the pH of the solution reaches 13 or 10 above, and causes crystals of an earth-metal titanate to form in the solution. The solution is thereafter filtered to produce an alkaline-earth metal titanate filter cake which is then dried and washed to produce the desired powder. At no time during the process is it necessary to apply any external heat to the solution. The heat of reaction is sufficient.
摘要翻译：通过将冰醋酸加入钛酸四异丙酯中来制备酰化钛酸溶液。然后加入蒸馏水直到溶液清除，并加入高等级的碱土金属碳酸盐如BaCO 3，SrCO 3或CaCO 3或其组合并搅拌直到土金属溶解并且溶液再次变得澄清。加入碱性氢氧化物如NaOH，直到溶液的pH达到13或10以上，并在溶液中形成土金属钛酸盐晶体。然后将溶液过滤以产生碱土金属钛酸盐滤饼，然后将其干燥并洗涤以产生所需的粉末。在此过程中，任何时候都不得不对溶液施加任何外部热量。反应热是足够的。

115. 发明授权

US4500942A Temperature stable monolithic capacitors and ceramic compositions for producing same 失效
标题翻译：温度稳定的单片电容器和用于制造其的陶瓷组合物
公开(公告)号：US4500942A
公开(公告)日：1985-02-19
申请号：US440804
申请日：1982-11-12
申请人： James M. Wilson
发明人： James M. Wilson
IPC分类号： C04B35/462 , H01G4/12 , C04B35/46
CPC分类号： H01G4/1227 , C04B35/462
摘要： Multilayer ceramic capacitors, and in particular NPO class capacitors are produced from dielectric compositions comprising a mixture of BaO, PbO, Nd.sub.2 O.sub.3, Bi.sub.2 O.sub.3, TiO.sub.2 and one of the rare earth oxides selected from the group consisting of Pr.sub.6 O.sub.11 and Sm.sub.2 O.sub.3, the selected rare earth oxide being present in an amount ranging from approximately 10 to 100 wt. % of the amount of Nd.sub.2 O.sub.3 in the mixture. In one embodiment an acrylic binder is added to the mixture to produce ceramic sheets which are screen printed with a Pt-Pd-Au electrode, and then cut into thin layers, stacked, laminated, sintered and terminated to produce a multilayer capacitor having an extremely stable TC and effective dielectric constant as high as 120. A high bismuth glass frit composition may be mixed with the dielectric ceramic mixture to produce a low sintering temperature mixture which is processed as above and then screen printed with a Ag-Pd alloy and laminated to produce a multilayer capacitor which can be sintered at a temperature as low as 1100.degree. C.
摘要翻译：多层陶瓷电容器，特别是NPO类电容器由包含BaO，PbO，Nd 2 O 3，Bi 2 O 3，TiO 2和选自Pr 6 O 11和Sm 2 O 3中的一种稀土氧化物的混合物的介电组合物制备，所选择的稀土氧化物存在量为约10至100重量％。混合物中Nd2O3的量的百分比。在一个实施方案中，将丙烯酸粘合剂加入到混合物中以产生丝网印刷Pt-Pd-Au电极的陶瓷片，然后切成薄层，堆叠，层压，烧结和终止，以产生具有极高的稳定的TC和高达120的有效介电常数。可将高铋玻璃料组合物与介电陶瓷混合物混合以产生低烧结温度混合物，其如上所述进行处理，然后用Ag-Pd合金丝网印刷并层压至生产可在低至1100℃的温度下烧结的多层电容器。

116. 发明授权

US09529974B2 System and method for detecting, collecting, analyzing, and communicating event-related information 有权
标题翻译：用于检测，收集，分析和传送事件相关信息的系统和方法
公开(公告)号：US09529974B2
公开(公告)日：2016-12-27
申请号：US13192160
申请日：2011-07-27
申请人： Peter C. Li , Jeffrey R. Collmann , Jane W. Blake , James M. Wilson , Jae I. Yoon , Manabu Torii , Carla S. Thomas
发明人： Peter C. Li , Jeffrey R. Collmann , Jane W. Blake , Mark G. Polyak , James M. Wilson , Jae I. Yoon , Manabu Torii , Carla S. Thomas
IPC分类号： G06F15/16 , G06F19/00 , H04L29/08 , G06F17/30 , G06Q10/04 , G06Q50/22 , G06Q50/26 , G06F12/00
CPC分类号： G06F19/3493 , G06F17/30616 , G06F19/00 , G06Q10/04 , G06Q50/22 , G06Q50/26 , G16H50/80 , H04L29/08072 , Y02A90/22 , Y02A90/24
摘要： A system and method involves detecting operational social disruptive events on a global scale, assigning event staging and warnings to express data in more simplistic terms, modeling data in conjunction with linguistics analysis to establish responsive actions, generating visualization and modeling capabilities for communicating information, and modeling propagation of events for containment and forecasting purposes.
摘要翻译：一种系统和方法涉及在全球范围内检测运营的社会破坏性事件，分配事件分段和警告以更简单的术语表达数据，结合语言学分析建模数据以建立响应动作，生成用于传达信息的可视化和建模能力，以及用于遏制和预测目的的事件建模传播。

117. 发明授权

US09250410B2 Optical fiber cable and interconnect assembly 有权
标题翻译：光纤电缆和互连组件
公开(公告)号：US09250410B2
公开(公告)日：2016-02-02
申请号：US13421463
申请日：2012-03-15
申请人： Terry L. Cooke , Christopher S. Houser , William C. Hurley , Samuel D. Navé , James M. Wilson
发明人： Terry L. Cooke , Christopher S. Houser , William C. Hurley , Samuel D. Navé , James M. Wilson
IPC分类号： G02B6/36 , G02B6/44 , G02B6/38
CPC分类号： G02B6/4472 , G02B6/3885 , Y10T29/49826 , Y10T29/49863
摘要： An optical fiber cable includes a jacket and modules including optical fibers. The jacket has an interior that forms an elongate conduit between proximal and distal ends. The modules extend lengthwise through the conduit without being bound together in a pattern of twisting or wound together in a pattern of stranding. Also, the jacket and modules are sized such that free space is provided within the conduit between the modules and the jacket. The jacket is at least ten meters long, and the orientation, alignment, and size of the modules allow individual modules to slide lengthwise relative to one another through the conduit. Pulling one of the modules from the proximal end of the jacket while holding the other modules fixed at the distal end of the jacket draws the one module further into the jacket on the distal end of the jacket.
摘要翻译：光纤电缆包括护套和包括光纤的模块。护套具有在近端和远端之间形成细长导管的内部。这些模块纵向延伸穿过导管，而不会以绞合的形式以扭曲或缠绕在一起的方式结合在一起。此外，护套和模块的尺寸使得在模块和护套之间的导管内提供自由空间。护套长度至少为十米，模块的取向，对准和尺寸允许各个模块通过导管相对于彼此纵向滑动。在夹持固定在护套的远端的其他模块的同时从护套的近端拉出模块中的一个将另一个模块进一步拉入护套的远端上的护套。

118. 发明授权

US08962330B2 Adeno-associated virus (AAV) serotype 8 sequences, vectors containing same, and uses therefor 有权
公开(公告)号：US08962330B2
公开(公告)日：2015-02-24
申请号：US11981022
申请日：2007-10-31
申请人： Guangping Gao , James M. Wilson , Mauricio R. Alvira
发明人： Guangping Gao , James M. Wilson , Mauricio R. Alvira
IPC分类号： C12N15/63 , C12N15/85 , A61K35/76 , C07K14/005 , C07K14/755 , C12N7/00 , C12N15/86 , A61K48/00
CPC分类号： C12N15/86 , A61K9/0019 , A61K35/761 , A61K38/177 , A61K38/45 , A61K38/4846 , A61K48/00 , C07K14/005 , C07K14/705 , C07K14/755 , C12N7/00 , C12N9/1018 , C12N9/644 , C12N2750/14122 , C12N2750/14143 , C12N2750/14152 , C12N2830/008 , C12N2830/48 , C12N2830/85 , C12Y201/03003 , C12Y304/21021 , C12Y304/21022
摘要： Sequences of a serotype 8 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such host cells and vectors in production of rAAV particles.

119. 发明授权

US08770863B2 Multi-fiber fiber-optic connector with switchable polarity key 有权
标题翻译：具有可切换极性的多光纤光纤连接器
公开(公告)号：US08770863B2
公开(公告)日：2014-07-08
申请号：US13487734
申请日：2012-06-04
申请人： Terry L. Cooke , Christopher S. Houser , Ronald A. Leonard , James M. Wilson
发明人： Terry L. Cooke , Christopher S. Houser , Ronald A. Leonard , James M. Wilson
IPC分类号： G02B6/36 , G02B6/38
CPC分类号： G02B6/3831 , G02B6/3851 , G02B6/3885 , G02B6/3895 , G02B6/3897
摘要： A multi-fiber fiber optic connector is configured to include a switchable polarity key that can be used to define first and second polarity configurations for the connector. The connector has a multi-fiber ferrule surrounded by an inner housing. The inner housing has top and bottom recesses sized to accommodate the polarity key. The polarity key is removably secured in either a top or bottom recess using a latching feature. The polarity of the connector can be switched by moving the polarity key from one position in the connector to the other rather than having to disassemble the connector.
摘要翻译：多光纤光纤连接器被配置为包括可切换的极性键，其可以用于限定连接器的第一和第二极性配置。连接器具有被内壳包围的多纤维套圈。内壳具有尺寸适应极性键的顶部和底部凹槽。使用锁定特征，极性键可拆卸地固定在顶部或底部凹部中。可以通过将极性键从连接器中的一个位置移动到另一个而不必拆卸连接器来切换连接器的极性。

120. 发明申请

US20130323226A1 Compositions and Methods for Altering Tissue Specificity and Improving AAV9-Mediated Gene Transfer 有权
标题翻译：改变组织特异性和改善AAV9介导的基因转移的组合物和方法
公开(公告)号：US20130323226A1
公开(公告)日：2013-12-05
申请号：US13985630
申请日：2012-02-17
申请人： James M. Wilson , Christie L. Bell , Luc H. Vandenberghe
发明人： James M. Wilson , Christie L. Bell , Luc H. Vandenberghe
IPC分类号： A61K31/7088 , A61K31/685 , A61K38/47
CPC分类号： A61K31/7088 , A61K31/685 , A61K38/47 , C12N15/86 , C12N2750/14043 , C12N2750/14045 , C12N2810/6027
摘要： A method of altering the targeting and/or cellular uptake efficiency of an adeno-associated virus (AAV) viral vector having a capsid containing an AAV9 cell surface binding domain is described. The method involves modifying a clade F cell surface receptor which comprises a glycan having a terminal sialic acid residue and a penultimate β-galactose residue. The modification may involve retargeting the vector by temporarily functionally ablate AAV9 binding in a subset of cells, thereby redirecting the vector to another subset of cells. Alternatively, the modification may involve increasing cellular update efficiency by treating the cells with a neuraminidase to expose cell surface β-galactose. Also provided are compositions containing the AAV9 vector and a neuraminidase. Also provided is a method for purifying AAV9 using β-galactose linked to solid support. Also provided are mutant vectors which have been modified to alter their targeting specificity, including mutant AAV9 in which the galactose binding domain is mutated and AAV in which an AAV9 galactose binding domain is engineered.
摘要翻译：描述了改变具有包含AAV9细胞表面结合结构域的衣壳的腺相关病毒（AAV）病毒载体的靶向和/或细胞摄取效率的方法。该方法包括修饰进化枝F细胞表面受体，其包含具有末端唾液酸残基的聚糖和倒数第二半乳糖残基。该修饰可能涉及通过临时功能地消融细胞子集中的AAV9结合来重新定向载体，从而将载体重定向到另一个细胞亚群。或者，修饰可以涉及通过用神经氨酸酶处理细胞以暴露细胞表面β-半乳糖来增加细胞更新效率。还提供了含有AAV9载体和神经氨酸酶的组合物。还提供了使用与固体支持物连接的β-半乳糖来纯化AAV9的方法。还提供已被修饰以改变其靶向特异性的突变载体，包括其中半乳糖结合结构域突变的突变AAV9和其中AAV9半乳糖结合结构域被工程化的AAV。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式