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    • 102. 发明申请
    • SYNTHESIS OF TRANS-TERT-BUTYL-2-AMINOCYCLOPENTYLCARBAMATE
    • 转化叔丁基-2-氨基环戊二烯酸的合成
    • US20100120031A1
    • 2010-05-13
    • US12441925
    • 2007-09-21
    • Daniel H. AppellaQun XuNing Zhang
    • Daniel H. AppellaQun XuNing Zhang
    • C12Q1/68C07C271/06C07C233/01C07C247/02C07K1/00G01N33/48C07K9/00
    • C07C271/24C07B2200/07C07C303/40C07C2601/08C07K14/003Y10T436/143333C07C311/20
    • The present invention concerns methods of synthesis of trans-tert-butyl-2-aminocylcopentylcarbamate comprising contacting 6-tosyl-6-azabicyclo[3.1.0]hexane with TMSN3 and TBAF to produce 2-azido-N-tosylcyclopentananiine; reducing the 2-azido-N-tosylcyclopentanamine to produce 2-amino-N-tosylcyclopentanamine; contacting the 2-amino-N-tosylcyclopentanamine with di-tert/-butyl dicarbonate to produce tert-butyl-2-(tosylamino)cyclopentylcarbamate; and detosylation of tert-butyl O(tosylamino) cyclopentylcarbamate to produce trans-tert-butyl-2-aminocyclopentylcarbamate. The invention also concerns PNAs comprising residues of the monomers of the invention in the backbone and uses of such PNAs. The PNAs of the invention can be used to detect DNAs of infectious agents or to suppress expression of protein associated with cancer.
    • 本发明涉及合成反式 - 叔丁基-2-氨基十八烷基戊基氨基甲酸酯的方法,其包括使6-甲苯磺酰基-6-氮杂双环[3.1.0]己烷与TMSN3和TBAF接触以产生2-叠氮基-N-甲苯磺酰基大环内酯; 还原2-叠氮-N-甲苯磺酰基环戊胺以制备2-氨基-N-甲苯磺酰基环戊胺; 使2-氨基-N-甲苯磺酰基环戊胺与二碳酸二叔丁酯接触以产生叔丁基-2-(甲苯磺酰氨基)环戊基氨基甲酸酯; 和叔丁基O(甲苯磺酰氨基)环戊基氨基甲酸酯的去甲苯基化,得到反式 - 叔丁基-2-氨基环戊基氨基甲酸酯。 本发明还涉及包含骨架中本发明的单体的残基的这些PNA的用途和这种PNA的用途。 本发明的PNA可用于检测感染因子的DNA或抑制与癌症相关的蛋白质的表达。
    • 103. 发明授权
    • Publishing interface for publishing content from a content-authoring application to a content server
    • 用于将内容从内容创作应用程序发布到内容服务器的发布界面
    • US07568003B2
    • 2009-07-28
    • US10401490
    • 2003-03-28
    • Ning ZhangShiu-Kai LeeArul Murugan KumaravelRajivk Kumar
    • Ning ZhangShiu-Kai LeeArul Murugan KumaravelRajivk Kumar
    • G06F15/16
    • G06F17/3089
    • A publishing interface is provided for a user to publish content to a content management server (CMS). The content is authored on a work station by way of an authoring application operating thereon and includes a main body and at least one linked object. Each linked object is linked to the main body by a local pointer therein. The CMS is for effectuating a web site including the published content. The publishing interface has a client-side component working with the application and a server-side component working with the CMS. The client-side component resolves each local pointer to a linked object in the main body, converts the main body into a pre-determined format as determined by the selected task, and forwards the converted main body and each linked object thereof to the server-side component. The server-side component stores the converted main body and the linked objects in the CMS.
    • 为用户提供发布界面,以将内容发布到内容管理服务器(CMS)。 内容通过在其上操作的创作应用程序在工作站上创作,并且包括主体和至少一个链接的对象。 每个链接的对象通过其中的本地指针链接到主体。 CMS用于实现包含已发布内容的网站。 发布界面有一个客户端组件与应用程序一起工作,一个服务器端组件与CMS一起工作。 客户端组件将每个本地指针解析为主体中的链接对象,将主体转换为由所选任务确定的预定格式,并将转换的主体及其每个链接对象转发到服务器端, 侧面组件。 服务器端组件将已转换的主体和链接的对象存储在CMS中。
    • 104. 发明申请
    • Method for Making Alkali Resistant Ultra Pure Colloidal Silica
    • 制备耐碱超纯胶体硅石的方法
    • US20080170979A1
    • 2008-07-17
    • US11965342
    • 2007-12-27
    • Yuhu WangNing Zhang
    • Yuhu WangNing Zhang
    • C01B33/14
    • C01B33/141
    • This patent disclose a method for making ultra pure colloidal silica having metal impurities except potassium of less than about 1 ppm, at a pH of greater than about 6, with an average particle size of less than about 200 nm. Hydrolyzable silanes that can be purified by distillation, or their oligomers, are used as raw materials which are first dissolved in water with organic or inorganic acids. This acidic solution is slowly mixed with a basic solution with or without silicate at a temperature range 50-105° C. to form colloidal silica. The colloidal silica can be further concentrated to higher concentrations, greater than about 20% by evaporation or by ultrafiltration, or a combination thereof.
    • 该专利公开了一种在大于约6的pH下制备具有低于约1ppm的除金属杂质以外的金属杂质的平均粒径小于约200nm的超纯胶体二氧化硅的方法。 可以通过蒸馏纯化的可水解硅烷或其低聚物用作原料,其首先用有机或无机酸溶解在水中。 将该酸性溶液与含有或不含硅酸盐的碱性溶液在50-105℃的温度范围内缓慢混合以形成胶体二氧化硅。 胶体二氧化硅可以进一步浓缩至更高的浓度,通过蒸发或通​​过超滤或其组合大于约20%。
    • 107. 发明申请
    • SKU determination mechanism and API
    • SKU决定机制和API
    • US20070083860A1
    • 2007-04-12
    • US11249118
    • 2005-10-12
    • Ajay BhaveNing Zhang
    • Ajay BhaveNing Zhang
    • G06F9/44
    • G06F9/445G06F9/44536
    • Applications or operating system components requiring a SKU, or other indicator of an operating system, make a call to an API. The calling application passes an indicator of the most current version of an operating system known at the time of the application creation as an argument. This argument may be an indictor of the operating system version, build number, and service pack version, for example. The called API may reference a table of operating system SKUs with the indicator of the most current operating system known to the calling application. If found, the API returns the corresponding SKU to the calling application. If not found, the API returns the SKU corresponding to the closest sequential match to the passed in indicator. The calling application may then execute believing it is using the operating system corresponding to the returned SKU.
    • 需要SKU或操作系统的其他指示器的应用程序或操作系统组件拨打API。 呼叫应用程序将作为应用程序创建时已知的最新版本的操作系统的指示符传递给参数。 例如,该参数可能是操作系统版本,版本号和Service Pack版本的指示符。 所呼叫的API可以引用具有呼叫应用程序已知的最新操作系统的指示符的操作系统SKU表。 如果找到,则API将相应的SKU返回给调用应用程序。 如果没有找到,则API将对应于最接近的顺序匹配的SKU返回给传入的指示符。 然后,呼叫应用程序可以执行,相信它正在使用对应于返回的SKU的操作系统。
    • 110. 发明授权
    • Method for safety non-arcing electric connection and the device using
the same
    • 安全无电弧电连接方法及其使用方法
    • US5259778A
    • 1993-11-09
    • US911626
    • 1992-07-10
    • Ning Zhang
    • Ning Zhang
    • H01R13/213H01R13/453H01R13/707H01R13/71
    • H01R13/707H01R13/4532
    • A method for safety non-arcing electric connection and the device using the same, which are adapted to complete the electric connection of common domestic appliances with power supply. The device comprises a socket unit which consists of a socket cover, a socket case, an insertion element and a connection element, and a plug which has a position means. The method is performed by means of insertion and turning. Three positions are defined by several pairs of pillar shaped teeth which cooperate with a pair of pillar shaped projections on the inside of the socket case. Also, electrical contact is established and broken by rotation of the insertion element relative to the socket unit. The device has advantages of safety, simple structure, convenient operation and no arcing.
    • 一种用于安全无电弧电连接的方法和使用该方法的装置,其适于完成普通家用电器与电源的电连接。 该装置包括由插座盖,插座壳体,插入元件和连接元件组成的插座单元和具有位置装置的插头。 该方法通过插入和转动来执行。 三个位置由几对支柱形齿组成,与支架壳体内侧的一对柱形突起配合。 此外,通过插入元件相对于插座单元的旋转建立和断开电接触。 该装置安全,结构简单,操作方便,无电弧等优点。