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91. 发明授权

US08282565B2 Access needle pressure sensor device and method of use 有权
标题翻译：检针式压力传感器装置及使用方法
公开(公告)号：US08282565B2
公开(公告)日：2012-10-09
申请号：US12530830
申请日：2008-03-12
申请人： Srijoy Mahapatra , George T. Gillies
发明人： Srijoy Mahapatra , George T. Gillies
IPC分类号： A61B5/02
CPC分类号： A61B17/3401 , A61B5/0215 , A61B5/031 , A61B5/202 , A61B5/4887 , A61B5/6848 , A61B5/6869 , A61B5/7239 , A61B17/34 , A61B17/3403 , A61B2017/00243 , A61B2090/064 , A61B2562/0247
摘要： A tool and method of positioning and delivering medical devices and therapeutics within the pericardial space, as well as other body part or space. A needle is inserted into the chest through a sub-xiphoid puncture, and the pressure within the needle is monitored manometrically or otherwise sensed as the needle is advanced towards the pericardial space. By reading the pressure within the needle while it is advanced, the clinician is able to know that he or she is avoiding insertion of it into organs or spaces not intended to be the target location. In addition the retractable sharp edge allows the operator to access the space and cut tissue but do so safely by retracting the sharp edge.
摘要翻译：在心包空间以及其他身体部位或空间内定位和传送医疗装置和治疗剂的工具和方法。针穿刺穿刺胸部插入胸部，并且当针朝着心包空间前进时，针头内的压力被监测或者以其他方式感测。通过读取针头内的压力，临床医生能够知道他或她正在避免将其插入到不想成为目标位置的器官或空间中。此外，可伸缩的锋利边缘允许操作者访问空间并切割组织，但是通过缩回尖锐边缘来安全地进行。

92. 发明申请

US20120253211A1 SYSTEMS AND METHODS FOR VARYING BLOOD FLOW TO IDENTIFY AUTOREGULATORY RANGES IN A PATIENT 有权
标题翻译：改变血液流动的系统和方法，以确定患者的自动护理范围
公开(公告)号：US20120253211A1
公开(公告)日：2012-10-04
申请号：US13433348
申请日：2012-03-29
申请人： Ken M. Brady , Robert A. Baruch
发明人： Ken M. Brady , Robert A. Baruch
IPC分类号： A61B5/026 , A61M1/36
CPC分类号： A61B5/02028 , A61B5/021 , A61B5/026 , A61B5/031 , A61B5/14553 , A61M1/10 , A61M1/1086 , A61M1/3666 , A61M1/3667 , A61M2205/33 , A61M2205/3303 , A61M2205/3334
摘要： A method may include controlling a bypass pump to introduce blood flow variations to a patient. The method may also include analyzing blood volume in the brain of the patient with respect to the blood flow variations and determining, based on the analyzing, whether an autoregulatory mechanism associated with the brain is operating properly.
摘要翻译：方法可以包括控制旁路泵以向患者引入血流变化。所述方法还可以包括分析患者脑中相对于血液流动变化的血容量，并且基于分析确定与大脑相关的自动调节机制是否正常工作。

93. 发明授权

US08277385B2 Method and apparatus for non-invasive assessment of hemodynamic and functional state of the brain 有权
标题翻译：用于非侵入性评估脑血流动力学和功能状态的方法和装置
公开(公告)号：US08277385B2
公开(公告)日：2012-10-02
申请号：US12700619
申请日：2010-02-04
申请人： Chris Berka , Daniel J. Levendowski , Djordje Popovic , Philip R. Westbrook
发明人： Chris Berka , Daniel J. Levendowski , Djordje Popovic , Philip R. Westbrook
IPC分类号： A61B5/02 , A61B5/04 , A61B5/00
CPC分类号： A61B5/031 , A61B5/02433 , A61B5/048 , A61B5/4094
摘要： A method and apparatus for assessment of hemodynamic and functional state of the brain is disclosed. In one embodiment, the method and apparatus includes non-invasive measurement of intracranial pressure, assessment of the brain's electrical activity, and measurement of cerebral blood flow. In some embodiments, the method and apparatus include measuring the volume change in the intracranial vessels with a near-infrared spectroscopy or other optical method, measuring the volume change in the intracranial vessels with rheoencephalography or other electrical method, and measuring the brain's electrical activity using electroencephalography.
摘要翻译：公开了一种用于评估大脑血液动力学和功能状态的方法和装置。在一个实施例中，该方法和装置包括颅内压的非侵入性测量，脑电活动的评估和脑血流量的测量。在一些实施方案中，所述方法和装置包括用近红外光谱法或其他光学方法测量颅内血管的体积变化，通过脑电图或其他电气方法测量颅内血管的体积变化，并使用脑电图

94. 发明申请

US20120238885A1 METHOD AND APPARATUS FOR CONTINUOUSLY MONITORING INTRACRANIAL PRESSURE 有权
标题翻译：连续监测压力的方法和装置
公开(公告)号：US20120238885A1
公开(公告)日：2012-09-20
申请号：US13487619
申请日：2012-06-04
申请人： Arminas Ragauskas , Gediminas Daubaris , Vytautas Petkus , Renaldas Raisutis
发明人： Arminas Ragauskas , Gediminas Daubaris , Vytautas Petkus , Renaldas Raisutis
IPC分类号： A61B5/0205
CPC分类号： A61B8/10 , A61B5/031 , A61B5/6843 , A61B8/06 , A61B8/4209 , A61B8/4227
摘要： A method and apparatus for continuously measuring the absolute intracranial pressure in a non-invasive manner is described by using an ultrasonic Doppler device which detects the pulsatility indexes of the blood flow inside the eye artery for both intracranial and extracranial eye artery portions. The eye in which the blood flow is monitored is subjected to a small pressure, sufficient to equalize the pulsatility index measurements of the internal and external portions of the eye artery. The pressure at which such equalization occurs is used as a reference for autocalibration of the apparatus so that continuous absolute intracranial pressure measurements may be taken over a particular sampling period.
摘要翻译：通过使用检测颅内和颅外动脉部分的眼动脉内的血流的搏动指数的超声多普勒装置来描述以非侵入性方式连续测量绝对颅内压的方法和装置。监测血流的眼睛经受足够小的压力，以均衡眼动脉的内部和外部的搏动指数测量值。将这种均衡发生的压力用作装置的自动校准的参考，使得可以在特定采样周期上进行连续的绝对颅内压测量。

95. 发明授权

US08108033B2 Techniques for data retention upon detection of an event in an implantable medical device 有权
标题翻译：检测植入式医疗设备中的事件时的数据保留技术
公开(公告)号：US08108033B2
公开(公告)日：2012-01-31
申请号：US11264974
申请日：2005-11-02
申请人： Touby A. Drew , Jonathon E. Giftakis , David L. Carlson , Eric J. Panken , Jonathan C. Werder , Nina M. Graves
发明人： Touby A. Drew , Jonathon E. Giftakis , David L. Carlson , Eric J. Panken , Jonathan C. Werder , Nina M. Graves
IPC分类号： A61B5/04
CPC分类号： A61B5/4094 , A61B5/0006 , A61B5/0031 , A61B5/02055 , A61B5/021 , A61B5/024 , A61B5/031 , A61B5/04001 , A61B5/04012 , A61B5/0402 , A61B5/0476 , A61B5/0816 , A61B5/1118 , A61B5/165 , A61B5/4082 , A61B5/686 , A61B5/7232 , A61B5/7282 , A61N1/36132 , A61N1/36135 , A61N1/36521 , A61N1/36585 , A61N1/3702 , A61N1/37252 , A61N1/37282 , G06F17/30336 , G06F19/00 , G06F19/3418 , G16H10/60 , G16H40/63
摘要： Methods and apparatus for storing data records associated with a medical monitoring event in a data structure. Upon detection of a possible occurrence of a physiological event by one group of monitoring elements, an implanted device records data received from another group of monitoring elements. The implanted device obtains and stores the data in the data record in a first data structure that is age-based. Before an oldest data record is lost, the oldest data record may be stored in a second data structure that is priority index-based. The priority index may be determined by a severity level and may be further determined by associated factors. The implanted device may organize, off-load, report, and/or display a plurality of data records based on an associated priority index. Additionally, the implanted device may select a subset or composite of physiologic channels from the available physiologic channels based on a selection criterion.
摘要翻译：用于存储与数据结构中的医疗监视事件相关联的数据记录的方法和装置。在通过一组监测元件检测到生理事件的可能发生时，植入装置记录从另一组监测元件接收的数据。植入装置以基于年龄的第一数据结构获得并存储在数据记录中的数据。在最旧的数据记录丢失之前，最早的数据记录可以存储在基于优先级索引的第二数据结构中。优先权索引可以由严重性级别确定，并且可以由相关因素进一步确定。植入的装置可以基于相关联的优先级索引来组织，卸载，报告和/或显示多个数据记录。另外，植入装置可以基于选择标准从可用生理通道中选择生理通道的子集或复合物。

96. 发明授权

US08088074B2 Cerebral vascular reactivity monitoring 有权
标题翻译：脑血管反应性监测
公开(公告)号：US08088074B2
公开(公告)日：2012-01-03
申请号：US12781105
申请日：2010-05-17
申请人： Robert A. Baruch , Ken M. Brady
发明人： Robert A. Baruch , Ken M. Brady
IPC分类号： A61B5/00
CPC分类号： A61B5/02007 , A61B5/02028 , A61B5/021 , A61B5/031 , A61B5/14546 , A61B5/14553 , A61B5/4076
摘要： A monitoring device may include logic to receive arterial blood pressure data associated with a patient and receive tissue hemoglobin data associated with the patient. The logic may also calculate a linear correlation between the arterial blood pressure data and the tissue hemoglobin data. The correlation may be used to assess vascular reactivity.
摘要翻译：监测装置可以包括用于接收与患者相关联的动脉血压数据并接收与患者相关联的组织血红蛋白数据的逻辑。逻辑还可以计算动脉血压数据和组织血红蛋白数据之间的线性相关性。相关性可用于评估血管反应性。

97. 发明授权

US08024045B2 Multi-functional burr hole assembly 有权
标题翻译：多功能毛刺孔组件
公开(公告)号：US08024045B2
公开(公告)日：2011-09-20
申请号：US12028085
申请日：2008-02-08
申请人： Keith Carlton , Alan Greszler , Scott Kokones
发明人： Keith Carlton , Alan Greszler , Scott Kokones
IPC分类号： A61N1/36
CPC分类号： A61N1/0529 , A61B5/01 , A61B5/031 , A61B5/0476 , A61B5/6864 , A61B2562/0219 , A61N1/0534 , A61N1/0539 , A61N1/086 , A61N1/36082 , A61N1/3718
摘要： A burr hole assembly for use in neurosurgery. In one aspect, the burr hole assembly comprises a burr hole portion and one or more sensors, such as EEG sensors, temperature sensors, intracranial pressure sensors, or motion sensors. In certain embodiments, an input/output unit, which may include a multiplexer, provides a coupling between the sensors and a brain stimulation system which operates in cooperation with the burr hole assembly. In another aspect, the burr hole assembly comprises a burr hole portion and a rotation mechanism which operates in cooperation with an electrode lead. In certain embodiments, the burr hole assembly includes a control system for controlling the rotation mechanism. Also disclosed are systems comprising a burr hole assembly and various components of a brain stimulation system, such as pulse generators, electrode leads, lead extension, or external control systems.
摘要翻译：用于神经外科的钻孔组件。一方面，毛刺孔组件包括毛刺孔部分和一个或多个传感器，例如EEG传感器，温度传感器，颅内压力传感器或运动传感器。在某些实施例中，可包括多路复用器的输入/输出单元提供传感器与与钻孔组件协作操作的脑刺激系统之间的耦合。另一方面，毛刺孔组件包括与电极引线配合操作的毛刺孔部分和旋转机构。在某些实施例中，钻孔组件包括用于控制旋转机构的控制系统。还公开了包括钻孔组件和脑刺激系统的各种部件的系统，例如脉冲发生器，电极引线，引线延伸或外部控制系统。

98. 发明申请

US20110137182A1 METHODS AND DEVICES FOR ASSESSING INTRACRANIAL PRESSURE 有权
标题翻译：用于评估内压的方法和装置
公开(公告)号：US20110137182A1
公开(公告)日：2011-06-09
申请号：US12959821
申请日：2010-12-03
申请人： Anthony Bellezza , William Lai
发明人： Anthony Bellezza , William Lai
IPC分类号： A61B5/021
CPC分类号： A61B5/031 , A61B5/4029 , A61B6/03 , A61B6/504 , A61B8/04 , A61B8/06 , A61B8/0808 , A61B8/10 , A61B8/4472
摘要： Provided are methods for noninvasively assessing intracranial pressure (“ICP”) based on optic nerve sheath diameter (“ONSD”) and a blood velocity metric, such as pulsatility or resistivity index. Also provided are related devices and systems for performing the claimed methods.
摘要翻译：提供了基于视神经鞘直径（“ONSD”）和血液速度度量（例如搏动性或电阻率指数）的非侵入性评估颅内压（“ICP”）的方法。还提供了用于执行所要求保护的方法的相关设备和系统。

99. 发明申请

US20110112460A1 ADJUSTABLE VALVE SETTING WITH MOTOR CONTROL 有权
标题翻译：可调节阀门设置与电机控制
公开(公告)号：US20110112460A1
公开(公告)日：2011-05-12
申请号：US12614580
申请日：2009-11-09
申请人： John Murdock Murphy
发明人： John Murdock Murphy
IPC分类号： A61M39/22 , F16K31/02
CPC分类号： A61M27/006 , A61B5/0031 , A61B5/031 , A61B2560/0219 , F16K31/0675 , F16K37/0041 , Y10T137/7878
摘要： An implantable medical device is disclosed that includes a valve body and a valve rotor adjustable with respect to the valve body. A tool can be utilized to determine and control a position of the valve rotor with respect to the valve body. The tool can include a valve body position reader, a valve rotor position reader and a valve rotor position controller to determine a valve setting for the device and adjust the valve setting as desired.
摘要翻译：公开了一种植入式医疗装置，其包括阀体和相对于阀体可调节的阀转子。可以使用工具来确定和控制阀转子相对于阀体的位置。该工具可以包括阀体位置读数器，阀转子位置读数器和阀转子位置控制器，以确定装置的阀设置并根据需要调节阀设置。

100. 发明申请

US20110060245A1 DEVICE FOR MEASURING INTRACRANIAL PRESSURE IN NEWBORNS AND BABIES AND A SUPPORTING MEMBER FOR SAID DEVICE 审中-公开
标题翻译：用于测量新生儿和婴幼儿体内压力的装置以及用于装置的支撑构件
公开(公告)号：US20110060245A1
公开(公告)日：2011-03-10
申请号：US12736773
申请日：2009-03-27
申请人： Gennadiy Konstantinovich Piletskiy , Nikolai Gennadyevich Piletskiy
发明人： Gennadiy Konstantinovich Piletskiy , Nikolai Gennadyevich Piletskiy
IPC分类号： A61B5/03
CPC分类号： A61B5/031
摘要： The invention relates to medicine. The inventive device for measuring intracranial pressure in newborns and babies comprises a body, a supporting member with a leveling surface on the end face thereof, a movable bush which is provided with the supporting member coaxially attached thereto and which bush is arranged in the body so as to be capable of carrying out a limited reciprocating motion to produce a static load on the bregmatic fontanel, a rod with a flat base which is accommodated in the movable bush cavity so as to be capable of moving with respect to the supporting member and producing an impact action for deforming the bregmatic fontanel, a rod moving system provided with a measuring coil which is connected to a control, processing and display unit for converting a signal received from the measuring coil in order to determine the intracranial pressure and display the obtained results. The supporting member is designed in the form of a bush with a leveling surface on the end face and is provided on the outer side with a limiter of the deformation produced by the static load on the bregmatic fontanel, the leveling surface of the supporting member is projected beyond the contact surface of the limiter, wherein said contact surface is inclined to a plane which is tangent to the leveling surface in such a way that a distance between the contact surface and the tangent plane increases in the direction towards the periphery of the limiter of the deformation produced by the static load on the bregmatic fontanel.
摘要翻译：本发明涉及药物。用于测量新生儿和婴儿颅内压的本发明的装置包括：身体，在其端面具有平整表面的支撑构件;可动衬套，其设置有同轴地附接到其上的支撑构件，并且衬套布置在主体中为了能够进行有限的往复运动以在主体囟体上产生静态载荷，具有平坦的底座的杆，容纳在可动衬套腔中，以便能够相对于支撑构件移动并产生用于使凸起的囟门变形的冲击动作，设置有测量线圈的杆移动系统，其连接到用于转换从测量线圈接收的信号的控制，处理和显示单元，以便确定颅内压力并显示所获得的结果。支撑构件被设计成具有在端面上的平整表面的衬套的形式，并且在外侧上设置有限制器，该限制器由侧壁囟门上的静载荷产生，变形表面是支撑构件的平整表面突出超过限制器的接触表面，其中所述接触表面倾斜于与调平表面相切的平面，使得接触表面和切平面之间的距离朝向限制器的周边的方向增加的静态载荷产生的变形。

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