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91. 发明授权

US09636069B2 System and method for monitoring and classifying atrial fibrillations 有权
公开(公告)号：US09636069B2
公开(公告)日：2017-05-02
申请号：US14739399
申请日：2015-06-15
申请人： Medtronic Monitoring, Inc.
发明人： Niranjan Chakravarthy , Abhi Chavan
IPC分类号： A61B5/046 , A61B5/00 , A61B5/11 , A61B5/0205 , A61B5/0404 , A61B5/0408
CPC分类号： A61B5/7264 , A61B5/0006 , A61B5/0205 , A61B5/0404 , A61B5/0408 , A61B5/046 , A61B5/1118 , A61B5/6832 , A61B5/7278 , A61B5/7289 , A61B2562/04
摘要： A system and method of detecting and classifying atrial fibrillations (AFs) monitors an electro-cardiogram (ECG) signal of the patient. Based on the monitored ECG signals, AF episodes are detected. Monitored physiological parameters are utilized to determine an activity level of the patient at the time of the detected AF episode, wherein the activity level is associated with the detected AF episode. The etiology of the detected AF episodes is classified as adrenergic if the AF episodes occur while the patient is active, and classified as vagal if the AF episodes occur while the patient is at rest.

92. 发明授权

US09629554B2 Microscopy imaging device with advanced imaging properties 有权
公开(公告)号：US09629554B2
公开(公告)日：2017-04-25
申请号：US14857156
申请日：2015-09-17
申请人： The Board of Trustees of the Leland Stanford Junior University
发明人： Kunal Ghosh , Laurie Burns , Abbas El Gamal , Mark J. Schnitzer , Eric Cocker , Tatt Wei Ho
IPC分类号： A61B5/00 , G02B21/16 , G02B21/36 , G02B21/00 , G01N21/64 , G02B3/00 , G02B27/14 , G06T7/00 , H04N5/225 , H04N5/232 , A61B90/20 , A61B90/30
CPC分类号： A61B5/0071 , A61B5/0042 , A61B5/0082 , A61B5/489 , A61B90/20 , A61B2090/306 , A61B2503/40 , A61B2503/42 , A61B2562/0233 , A61B2562/04 , A61B2576/026 , G01N21/6458 , G02B3/0087 , G02B21/0008 , G02B21/008 , G02B21/16 , G02B21/36 , G02B21/361 , G02B21/362 , G02B21/365 , G02B27/141 , G06T7/0012 , G06T2207/30016 , G06T2207/30101 , H04N5/2254 , H04N5/2256 , H04N5/23296
摘要： Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.

93. 发明申请

US20170067856A1 TRANSDUCER UNIT, ACOUSTIC PROBE INCLUDING THE TRANSDUCER UNIT, AND PHOTOACOUSTIC APPARATUS INCLUDING THE ACOUSTIC PROBE 审中-公开
标题翻译：传感器单元，包括传感器单元的声学探头和包含声学探头的光电设备
公开(公告)号：US20170067856A1
公开(公告)日：2017-03-09
申请号：US15253419
申请日：2016-08-31
申请人： CANON KABUSHIKI KAISHA
发明人： Atsushi Kandori
IPC分类号： G01N29/24
CPC分类号： G01N29/2406 , A61B5/0095 , A61B5/4312 , A61B5/708 , A61B8/0825 , A61B8/4209 , A61B8/4488 , A61B2562/0204 , A61B2562/04 , G01H11/00 , G01N29/0654 , G01N29/2418 , G01N2291/101 , H01L2224/48091 , H01L2224/73265 , H01L2924/00014
摘要： A transducer unit includes a substrate, a capacitive transducer provided on the substrate and configured to receive an acoustic wave generated when a subject is irradiated with light from a light source and output an electric signal, a circuit substrate including a current/voltage conversion circuit configured to convert a current output from the capacitive transducer into a voltage, and a flexible printed wiring that electrically connects the capacitive transducer to the current/voltage conversion circuit, in which the circuit substrate is provided on a surface side opposite to a surface where the capacitive transducer is provided among surfaces of the substrate.
摘要翻译：传感器单元包括基板，设置在基板上的电容换能器，其被配置为接收当用物体照射来自光源的光并产生电信号时产生的声波，电路/电压转换电路构成的电路基板将电容式换能器的电流输出转换为电压，以及将电容式换能器电连接到电流/电压转换电路的柔性印刷布线，其中电路基板设置在与电容传感器设置在基板的表面之间。

94. 发明申请

US20170065228A1 BIOLOGICAL INFORMATION MEASUREMENT APPARATUS AND BIOLOGICAL INFORMATION MEASUREMENT METHOD 审中-公开
标题翻译：生物信息测量装置和生物信息测量方法
公开(公告)号：US20170065228A1
公开(公告)日：2017-03-09
申请号：US15123402
申请日：2015-03-17
申请人： KYOCERA Corporation
发明人： Asao HIRANO
IPC分类号： A61B5/00 , A61B5/024
CPC分类号： A61B5/721 , A61B5/02416 , A61B5/11 , A61B5/6803 , A61B5/6817 , A61B5/7221 , A61B5/742 , A61B2562/04
摘要： A biological information measurement apparatus includes a plurality of biological sensors of the same type (111a and 111b) and a controller (120) that measures biological information based on biological measurement outputs obtained from the biological sensors (111a and 111b).
摘要翻译：一种生物信息测量装置，包括多个相同类型的生物传感器（111a和111b）和根据从生物传感器（111a和111b）获得的生物测量输出来测量生物信息的控制器（120）。

95. 发明授权

US09572984B2 System and method for coupling burst and tonic stimulation 有权
标题翻译：用于联合突发和强直刺激的系统和方法
公开(公告)号：US09572984B2
公开(公告)日：2017-02-21
申请号：US14563895
申请日：2014-12-08
申请人： PACESETTER, INC.
发明人： Wenbo Hou , Xiaoyi Min , Stuart Rosenberg
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36071 , A61B5/04001 , A61B5/4005 , A61B5/4824 , A61B5/4848 , A61B5/686 , A61B2562/04 , A61N1/0551 , A61N1/06 , A61N1/36057 , A61N1/36178
摘要： A system and method for delivering coupled burst and tonic stimulation of nervous tissue is provided. The system and method includes providing a lead with at least one stimulation electrode configured to be implanted at a target position proximate to nervous tissue of interest. The system and method further includes coupling the lead to an implantable pulse generator (IPG). The method delivers a first current pulse configured as a tonic stimulation waveform to the at least one electrode. The tonic stimulation waveform is configured to excite A-beta fibers of the nervous tissue. After a tonic-burst delay, the IPG delivers second current pulses configured as a burst stimulation waveform to at least one electrode. The burst stimulation waveform is configured to excite C-fibers of the nervous tissue.
摘要翻译：提供了一种用于输送神经组织的偶发爆发和强直刺激的系统和方法。该系统和方法包括提供具有至少一个刺激电极的引线，该至少一个刺激电极配置成植入靠近感兴趣的神经组织的目标位置。该系统和方法还包括将引线耦合到可植入脉冲发生器（IPG）。该方法将配置为补音刺激波形的第一电流脉冲传送到至少一个电极。滋补刺激波形被配置为激发神经组织的A-β纤维。在紧急突发延迟之后，IPG将配置为突发刺激波形的第二电流脉冲提供给至少一个电极。爆发刺激波形被配置为激发神经组织的C纤维。

96. 发明授权

US09572524B2 Method and apparatus for assay of electrochemical properties 有权
标题翻译：电化学性质测定方法和装置
公开(公告)号：US09572524B2
公开(公告)日：2017-02-21
申请号：US14919935
申请日：2015-10-22
申请人： AGAMATRIX, INC.
发明人： Sridhar G. Iyengar , Ian S. Harding
IPC分类号： G01N27/327 , G01N27/30 , A61B5/1495 , G01N27/26 , A61B5/1468 , G01N17/02 , A61B5/1473 , A61B5/00
CPC分类号： A61B5/1495 , A61B5/1468 , A61B5/1473 , A61B5/7203 , A61B2562/04 , G01N17/02 , G01N27/26 , G01N27/3273 , G01N27/3274
摘要： A method for monitoring a select analyte in a sample in an electrochemical system. The method includes applying to the electrochemical system a time-varying potential superimposed on a DC potential to generate a signal; and discerning from the signal a contribution from the select analyte by resolving an estimation equation based on a Faradaic signal component and a nonfaradaic signal component.
摘要翻译：一种用于监测电化学系统中样品中选择分析物的方法。该方法包括向电化学系统施加叠加在DC电位上的时变电位以产生信号; 并且通过基于法拉第信号分量和非法拉第信号分量来解析估计方程，从信号中识别来自选择分析物的贡献。

97. 发明申请

US20170006950A1 WIRELESS MONITORING OF SAFETY HELMETS 有权
标题翻译：无线监控安全卫士
公开(公告)号：US20170006950A1
公开(公告)日：2017-01-12
申请号：US15215989
申请日：2016-07-21
申请人： AT&T Intellectual Property I, L.P.
发明人： Robert R. Miller, II
IPC分类号： A42B3/04 , A61B5/11 , G08B21/04 , A61B5/00
CPC分类号： A42B3/046 , A61B5/0004 , A61B5/0022 , A61B5/11 , A61B5/1122 , A61B5/4064 , A61B5/6803 , A61B5/6898 , A61B5/7246 , A61B5/7264 , A61B5/7282 , A61B5/742 , A61B5/746 , A61B5/747 , A61B2562/0219 , A61B2562/0247 , A61B2562/028 , A61B2562/04 , A61B2562/043 , G08B21/043
摘要： Remote monitoring of a subject wearing a sports helmet is enabled. In one aspect, an example system includes a safety helmet and a sensor integrated with the helmet for continuously gathering head acceleration force data, the head acceleration force data associated with the head movements of a subject. The system can also include a wireless transceiver coupled to the sensor for transmitting the head acceleration force data and a mobile device for receiving the head acceleration force data from the wireless transceiver. The system can further include a database engine for displaying the head acceleration force data to a user.
摘要翻译：启用运动头盔受试者的远程监控。在一个方面，示例性系统包括安全头盔和与头盔集成的传感器，用于连续收集头部加速力数据，头部加速力数据与被摄体的头部运动相关联。该系统还可以包括耦合到传感器的无线收发器，用于发送头部加速力数据，以及用于从无线收发器接收头部加速力数据的移动装置。该系统还可以包括用于向用户显示头部加速力数据的数据库引擎。

98. 发明申请

US20170000389A1 BIOMECHANICAL INFORMATION DETERMINATION 审中-公开
标题翻译：生物力学信息测定
公开(公告)号：US20170000389A1
公开(公告)日：2017-01-05
申请号：US15199087
申请日：2016-06-30
申请人： Colorado Seminary, which owns and operates the University of Denver
发明人： Bradley Davidson , Michael Decker , Craig Simons , Kevin Shelburne , Daniel Jung Kim
IPC分类号： A61B5/11 , A61B5/00
CPC分类号： A61B5/1127 , A61B5/0022 , A61B5/0024 , A61B5/021 , A61B5/024 , A61B5/0488 , A61B5/1038 , A61B5/1112 , A61B5/1114 , A61B5/112 , A61B5/1122 , A61B5/1123 , A61B5/1126 , A61B5/14542 , A61B5/6804 , A61B5/6807 , A61B5/6828 , A61B5/6829 , A61B5/6843 , A61B5/7267 , A61B5/743 , A61B5/744 , A61B2562/0219 , A61B2562/028 , A61B2562/04
摘要： Systems and methods of the present disclosure may include initializing a first plurality of inertial measurement units (IMUs) and a second plurality of IMUs, and attaching the first plurality of IMUs to a first segment of a subject and the second plurality of IMUs to a second segment of the subject. Such a method may also include obtaining data from the first plurality of IMUs and the second plurality of IMUs as the subject performs a motion, and determining an absolute position of the first segment and the second segment based on the data.
摘要翻译：本公开的系统和方法可以包括初始化第一多个惯性测量单元（IMU）和第二多个IMU，以及将第一多个IMU附接到被摄体的第一段并将第二多个IMU附接到第二个主题段。这种方法还可以包括当对象执行运动时从第一多个IMU和第二多个IMU获得数据，以及基于该数据确定第一段和第二段的绝对位置。

99. 发明申请

US20160374585A1 THREE-DIMENSIONAL BIO-MEDICAL PROBE SENSING AND CONTACTING STRUCTURES WITH ADDRESSIBILITY AND TUNABILITY 审中-公开
标题翻译：三维生物医学探针和接触结构具有可接受性和可操作性
公开(公告)号：US20160374585A1
公开(公告)日：2016-12-29
申请号：US14901243
申请日：2014-06-26
申请人： THE PENN STATE RESEARCH FOUNDATION
发明人： Stephen J. Fonash , Wook Jun Nam
IPC分类号： A61B5/053
CPC分类号： A61B5/053 , A61B5/685 , A61B2562/028 , A61B2562/0285 , A61B2562/04
摘要： A three dimensional biomedical probe device is provided that includes a planar substrate. A probe structure is supported on the planar substrate. The probe structure has a base and a portion essentially perpendicular to the base extending along a length to a tip and has a linear dimension at the tip of said probe structure of between 5 nanometers (nm) and 5 microns thereby defining an AC, DC, or transient current, charge, or voltage sensing probe. In one variation, this probe is the electrical contact to the biomedical medium. In another variation this probe is the gate electrode of a field effect transistor (FET). An array of selectively electrically addressable such devices is also provided giving the ability to sample the physiological activity at many positions within cells, fluids and intercellular regions without the need for mechanical motion and inducing cellular lysis.
摘要翻译：提供了一种三维生物医学探针装置，其包括平面基底。探针结构支撑在平面基板上。探针结构具有基部和基本上垂直于基部的部分，该部分沿着长度延伸到尖端，并且在所述探针结构的尖端处具有在5纳米（nm）和5微米之间的线性尺寸，由此限定AC，DC，或瞬态电流，充电或电压感测探头。在一个变体中，该探针是与生物医学介质的电接触。在另一个变型中，该探针是场效应晶体管（FET）的栅电极。还提供了一组选择性可电寻址的这样的装置，其提供了在细胞，流体和细胞间区域内的许多位置上对生理活性进行采样的能力，而不需要机械运动并诱导细胞裂解。

100. 发明申请

US20160360978A1 Interferometric focusing beam optical cardiovascular sensor 审中-公开
标题翻译：干涉聚焦光束心血管传感器
公开(公告)号：US20160360978A1
公开(公告)日：2016-12-15
申请号：US15146354
申请日：2016-05-04
申请人： Omnisensing Photonics LLC
发明人： Wei Chen , Jin Zhang , Shan Zhong , Zhonghua Zhu
IPC分类号： A61B5/026 , A61B5/00 , A61B5/021
CPC分类号： A61B5/0261 , A61B5/02125 , A61B5/681 , A61B5/7278 , A61B2090/306 , A61B2562/0238 , A61B2562/04
摘要： This application discloses a potable, easy-to-use miniature cardiovascular sensor that is capable of monitoring heart rate, blood flow and blood pressure 24/7, using optical non-invasive method. It utilizes interferometric detection to improve signal to noise ratio. It also utilizes phase controlled focusing beam to reduce the optical power needed and therefore minimizing the power consumption, making it practical for continuous monitoring. The integrated optical chip assembly shrinks the total sensor size and makes it suitable for wearable devices, hence, this device will be portable and removable.
摘要翻译：该应用公开了一种使用光学非侵入性方法能够监测心率，血流量和血压的便携式易于使用的微型心血管传感器。它利用干涉检测来提高信噪比。它还采用相位控制聚焦光束来减少所需的光功率，从而最大限度地降低功耗，使其可以实现连续监测。集成的光学芯片组件缩小了传感器的总体尺寸，使其适合于可穿戴设备，因此该设备将是便携式和可移动的。

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